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The Benefits of B Complex Vitamins

By Cathy Wong, ND | Reviewed by Richard N. Fogoros, MD
Updated June 10, 2018

A B complex vitamin usually delivers eight of the B vitamins: B1 (thiamine ), B2

(riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine ), B7 (biotin), B9 (folic
acid), and B12 (cobalamin). Found naturally in meat, leafy greens, dairy, beans, peas, and
whole or fortified grains, B complex vitamins help your body make energy from the food you
eat, form red blood cells, and play an essential role in certain bodily functions. Take a closer
look at the benefits, signs of deficiency, and food sources for each of these B complex
vitamins.

B1 (Thiamine)
Health Benefits

Helps the body use carbohydrates from food to produce energy

Needed for the health of the brain, muscles, and nervous system
Critical for the growth, development, and function of cells in the body

Symptoms of Deficiency

Weight loss
Short-term memory loss
Weakness
Fatigue
Cardiovascular symptoms
Irritability
Beriberi

Food Sources

Common food sources of vitamin B1 include fortified breakfast cereal, enriched and whole
grain products (bread, breakfast cereals, rice, noodles, and flour), wheat germ, pork, trout,
black beans, mussels, and tuna.

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B2 (Riboflavin)
Health Benefits

Works with other B vitamins (helps convert B6 into a usable form and aids in niacin
production)
Helps convert food into energy
Needed for red blood cell production and growth
Keeps the eyes, nervous system, and skin healthy

Symptoms of Deficiency

Skin disorders

Swelling of the mouth and throat

Cracks at the corners of the mouth
Swollen, cracked lips
Hair loss
Sore throat
Sensitivity to light.

Food Sources

Common food sources of vitamin B2 include milk and dairy products, fortified breakfast
cereals, beef liver, clams, portobello mushrooms, almonds, and chicken.

B3 (Niacin)
Health Benefits

Aids in the conversion of food into energy

Helps enzymes in the body function properly by helping the body use other B vitamins
and make and repair DNA (the genetic material found in all body cells)
Needed for the production of hormones, such as sex and stress hormones
Helps with the function of the digestive and nervous systems and skin

Symptoms of Deficiency

Digestive problems
Canker sores
Fatigue
Inflamed skin
Poor circulation
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Depression
Vomiting
Pellagra

Food Sources

Common food sources of vitamin B3 include eggs, fish, fortified bread and cereal, rice, nuts,
milk and dairy, chicken, beef, turkey, lamb, organ meats, peanuts.

B5 (Pantothenic Acid)
Health Benefits

Breaks down fats and carbohydrates for energy

Plays a role in the production of sex and stress hormones in the adrenal glands and
neurotransmitters
Helps the body use other vitamins, such as riboflavin
Vitamin B5 is needed for the production of red blood cells and cholesterol

Symptoms of Deficiency

Burning feet
Depression
Fatigue
Insomnia

Irritability
Stomach pains
Upper respiratory tract infections
Vomiting

Food Sources

Common food sources of vitamin B5 include meat, avocado, broccoli, kale, eggs, milk,
mushrooms, fortified cereals, organ meats, poultry, potatoes, and legumes.

B6 (Pyridoxine)
Health Benefits

Needed by the body to use and store protein and carbohydrates from food (in the form
of glycogen, a stored energy in the muscles and liver)
Required for more than 100 enzyme reactions in the body. It aids in the formation of
hemoglobin (a substance in red blood cells that carries oxygen through blood) and
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neurotransmitters and hormones that influence mood and regulate the body's clock
Involved in immune function and brain development and function

Symptoms of Deficiency

Depression
Difficulty concentrating
Irritability
Muscle weakness
Nervousness
Short-term memory loss

Food Sources

Common food sources of vitamin B6 include chickpeas, beef liver, tuna, salmon, chicken
breast, fortified breakfast cereal, potatoes, turkey, fruits (except citrus), and beef.

B7 (Biotin)
Health Benefits

Helps the body convert the fats, carbohydrates, and proteins in the food that you eat
into energy
Needed to make fatty acids
Promotes growth and bone and hair health

Symptoms of Deficiency

Hair thinning or loss

Skin rashes around the eyes, nose, mouth, or other mucus membranes
Dry eyes
Brittle nails
Muscle pain

Food Sources

Common food sources of vitamin B7 include beef liver, egg yolk, wheat germ, pork, beef,
sunflower seeds, sweet potato, almonds, whole grain foods, sardines, spinach, and broccoli.

B9 (Folic Acid)
Health Benefits

Helps your body make red blood cells

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Needed to help cells make and maintain DNA

Reduces the risk of birth defects in the brain and spine, such as spina bifida

Symptoms of Deficiency

Diarrhea
Forgetfulness
Gingivitis
Loss of appetite
Shortness of breath
Irritability
Tongue inflammation
Poor growth

Food Sources

Common food sources of vitamin B9 (folate) include spinach, beef liver, broccoli, Brussels
sprouts, beans and legumes, asparagus, orange juice, peanuts, avocado, dark leafy greens,
fortified cereals, and salmon.

B12 (Cobalamin)
Health Benefits

Helps keep the nervous system and red blood cells healthy
Required for the formation of red blood cells and DNA
Important for protein metabolism

Symptoms of Deficiency

Fatigue
Weakness
Constipation
Lack of appetite
Weight loss
A type of anemia known as megaloblastic anemia
Numbness and tingling in the fingers and toes
Nerve damage

Food Sources

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Common food sources of vitamin B12 are found primarily in animal foods, such as beef liver
(and other organ meats), clams and other shellfish, beef, chicken, fish, eggs, milk and other
dairy products, and some fortified cereals.

Uses 
With a key role in converting food into fuel, proponents claim that B complex vitamins can
help with a variety of conditions, including anxiety, depression, heart
disease, and premenstrual syndrome (PMS).

In addition, some people take a vitamin B complex to increase energy, enhance mood,
improve memory, boost skin and hair health and stimulate the immune system.

While most people who eat a varied diet get enough B vitamins from food, some people are
at an increased risk of deficiency, particularly those who are over the age of 50, take antacid
medication, or have celiac disease, Crohn's disease, gastritis, or other digestive disorders.

If you have had stomach or weight loss surgery, drink alcohol regularly, or follow a vegetarian
or vegan diet, you may be more prone to a deficiency.

Pregnant and breastfeeding women may need more of vitamins B6, B12, and folic acid.

Possible Side Effects

Although B complex supplements are water-soluble and do not stay in the body for long,
large doses of the vitamins in supplement form can cause certain side effects:

B3 (niacin): Skin flushing or pain, elevated blood sugar levels, and liver toxicity.
B6 (pyridoxine): Nerve damage, skin lesions, worsening of kidney function, and
increased risk of heart attack, stroke, and death in people with diabetes and advanced
kidney disease. Recent studies have found that high doses of vitamin B6 were
associated with a slightly increased risk of hip fracture and increased risk of lung
cancer (when taken with vitamin B12).
B9 (folic acid): Kidney damage, increased insulin resistance in offspring, lower natural
killer cell activity in older women, and may be associated with increased risk of some
cancers. Can mask the diagnosis of a vitamin B12 deficiency.
B12 (cobalamin): Acne and rosacea in some people. Vitamin B12 has been found to
speed the decline in kidney function and increase the risk of cardiovascular events in
people with impaired kidney function. High doses of vitamin B12 taken with folic acid
have been associated with a greater risk of cancer and mortality.

There is a daily tolerable intake level (UL) for each B vitamin, which is above what most
people need. Getting more than the UL increases your chances of side effects.

A Word From Verywell

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To stay healthy, most people can get what they need by eating a varied, balanced diet filled
with delicious foods naturally rich in B vitamins, such as leafy greens, nuts, beans and
legumes, whole grains, lean protein, mushrooms, and eggs. There isn't solid evidence to
support taking excessive amounts of B vitamins if you're not deficient in them.

If you're not getting enough of a B vitamin from your diet, taking a vitamin B supplement may
be beneficial for some people. Deficiency in B vitamins can cause a number of symptoms,
including tiredness, anemia, loss of appetite, depression, abdominal pain, muscle cramps,
hair loss, and eczema.

Just be sure to consult your health care provider to find out whether a B complex
supplement is right for you (and if so, the appropriate amount considering the total daily
amount you are getting from food and supplements). 

Disclaimer: The information contained on this site is intended for educational purposes only and is not a
substitute for advice, diagnosis or treatment by a licensed physician. It is not meant to cover all possible
precautions, drug interactions, circumstances or adverse effects. You should seek prompt medical care for
any health issues and consult your doctor before using alternative medicine or making a change to your
regimen.

Sources:

Afriyie-Gyawu E, Ifebi E, Ampofo-Yeboah A, Kyte B, Shrestha S, Zhang J. Serum folate levels and fatality
among diabetic adults: A 15-y follow-up study of a national cohort. Nutrition. 2016 Apr;32(4):468-73. 

Kim SJ, Zuchniak A, Sohn KJ, et al. Plasma folate, vitamin B-6, and vitamin B-12 and breast cancer risk in
BRCA1- and BRCA2-mutation carriers: a prospective study. Am J Clin Nutr. 2016 Sep;104(3):671-7. 

Tio M, Andrici J, Cox MR, Eslick GD. Folate intake and the risk of prostate cancer: a systematic review and
meta-analysis. Prostate Cancer Prostatic Dis. 2014 Sep;17(3):213-9. 

Wang R, Zheng Y, Huang JY, Zhang AQ, Zhou YH, Wang JN. Folate intake, serum folate levels, and prostate
cancer risk: a meta-analysis of prospective studies. BMC Public Health. 2014 Dec 29;14:1326.

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