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neurprotective - Mandukaparni

Glycyrrhiza glabra

Guduchi

Shankhapushpi

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459457/

developmental disorders

OA is the most common type of degenerative joint disease. It is the major cause of pain and disability
affecting the elderly

long established roots in ethnopharmacology

There is currently no effective pharmacotherapy capable of restoring the original structure and function
of the damaged cartilage and other synovial tissues in OA

PRoblems- only a temp relief, no permanant cure, side effects of drugs , safer and more “natural”;
causes frustration

treating the root cause and correcting at the root level

Mesenchymal stem cells

Adult MSCs can be isolated from bone marrow, marrow aspirates, skeletal muscle, adipose tissue,
synovium and many other connective tissues

Growth factors and a three-dimensional high-density culture environment are important for the
differentiation of MSCs into chondrocytes,

Some of our recent work suggests that curcumin and resveratrol have the potential to promote
chondrogenic and osteogenic differentiation of MSCs by targeting NF-κB

The use of this strategy in-vitro may support the regeneration of articular cartilage in cell-based
cartilage-repair techniques, for example autologous chondrocyte implantation (ACI), because cell-based
repair of lesions in articular cartilage will be compromised in already inflamed joints.
Revestrol and curcumin to enhance cartilage regeneration by inducing stem cells,

brain development

Cognitive deficits that present with many of neuropsychiatric conditions and/or alone as developmental
deficit demand use of nootropics to boost cognitive abilities. Recently there is a tremendous urge to
explore medicinal plants globally for improving cognitive function owing to their less adverse effects

Some of our recent work suggests that curcumin and resveratrol have the potential to promote
chondrogenic and osteogenic differentiation of MSCs by targeting NF-κB

rigorous graduate curriculum

t is with gratitude that I have always looked toward the esteemed Literature department at [university
name] as a source of inspiration throughout my undergraduate and graduate education;

shadowing doctors in all major decipline of surgery in clinical attachment programs, it would touch a
raw nerve of me to see a chronically disabled child

goal is to help the most needy, which also directed me in the path of volunteering from volunteering at
the red cross as a frist aid provider to teaching science and english for underprivillaged students free of
charge.

that all humans should have an improved quality of life

I have worked within a wide variety of primary care settings including general medicine and surgery,
theatre, A&E and psychiatry.Each clinical discipline has brought new challenges, allowing me to form
working relationships with a large number of healthcare professionals and their patients.

Throughout my time at university I accumulated over 450 hours of direct patient contact, working in a
complementary medicine clinic.

stem cell is without limits, fascinating even to imagine what could be done

it was a question to me how patients who had surgery as the last resort with severely destroyed
cartilage along with the joint. the only possibility i could imagine was. If stem cells inducing properties of
the above mentioned is proven, it could also be tested for mesenchymal stem cells into differentiation
into any other organs of the body.

Mesenchymal stem cells from umbilical cord are considered to be universal donor cells

Currently, there is no cure for cerebral palsy. Research is mostly aimed at


finding ways to make life more manageable. stimulate repair of damaged nervous
tissue in both the brain a

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