PROPOSAL PENELITIAN

FORMULASI SEDIAAN TOPIKAL KRIM YANG MENGANDUNG

EKSTAK LIDAH BUAYA DAN EKSTRAK IKAN GABUS SEBAGAI
OBAT UNTUK MEMPERCEPAT PENYEMBUHAN LUKA BAKAR

Oleh :
DORA ROSALINA SAMOSIR
1501011

PROGRAM STUDI S1 FARMASI

SEKOLAH TINGGI ILMU FARMASI RIAU
YAYASAN UNIVERSITAS RIAU
2018
 DAFTAR ISI

DAFTAR ISI............................................................................................................................... i
BAB I PENDAHULUAN .......................................................................................................... 1
1.1. Latar Belakang .................................................................................................................... 1
1.2. Rumusan Masalah .............................................................................................................. 3
1.3 Tujuan Penelitian ................................................................................................................. 3
1.4 Mamfaat Penelitian ............................................................................................................. 3
BAB II TINJAUAN PUSTAKA ............................................................................................... 4
2.1. Uraian Ekstrak .................................................................................................................. 4
2.1.1. Lidah Buaya ............................................................................................................... 4
2.1.1.1. Klasifikasi Lidah buaya ...................................................................................... 5
2.1.1.2 Kandungan Senyawa Lidah Buaya ...................................................................... 5
2.1.2 Ikan Gabus ................................................................................................................. 7
2.1.2.1 Klasifikasi Ikan Gabus ......................................................................................... 8
2.1.2.2 Komponen Senyawa Bioakif Ikan Gabus ............................................................ 8
2.2 Krim ..................................................................................................................................... 10
2.3 Luka Bakar ........................................................................................................................... 11
2.4 Penyembuhan Luka Bakar ................................................................................................. 15
2.5 Data Preformulasi ................................................................................................................ 15
BAB III METODOLOGI PENELITIAN ................................................................................ 17
3.1 Waktu dan Tempat Penelitian ........................................................................................... 17
3.2 Alat dan Bahan.................................................................................................................... 17
3.3 Cara Kerja ............................................................................................................................ 18
3.3.1 Ekstraksi ........................................................................................................................ 18
3.3.2 Identifikasi Fitokimia Senyawa Ekstrak ....................................................................... 19
3.3.3 Pembuatan Krim ........................................................................................................... 20
3.3.3 Pembuatan Krim ........................................................................................................... 20
3.3.4 Daya Cuci Krim ............................................................................................................ 20
3.3.5 Pengujian Efek Krim .................................................................................................... 21
DAFTAR PUSTAKA ................................................................................................................. 22
LAMPIRAN SKEMA