SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Revision Date 08.06.2010

1. Identification of the substance/mixture and of the company/undertaking

Product Information
Catalogue No.: 104864
Product name: Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur
Use of the Reagent for analysis, Chemical production, Pharmaceutical production
Substance/Mixture and analysis

Company: Merck KGaA * 64271 Darmstadt * Germany * Phone:+49 6151 72-0

Emergency telephone: Please contact the regional Merck representation in your country.
Responsible/issuing person: EQ-EPS * e-mail: prodsafe@merck.de

2. Hazards identification
GHS Classification
Carcinogenicity, Category 1B H350: May cause cancer.
Germ cell mutagenicity, Category 1B H340: May cause genetic defects.
Reproductive toxicity, Category 1B H360FD: May damage fertility. May damage the
unborn child.
Oxidizing solid, Category 2 H272: May intensify fire; oxidiser.
Acute toxicity, Category 2, Inhalation H330: Fatal if inhaled.
Acute toxicity, Category 3, Oral H301: Toxic if swallowed.
Acute toxicity, Category 4, Dermal H312: Harmful in contact with skin.
Specific target organ toxicity - repeated H372: Causes damage to organs through
exposure, Category 1 prolonged or repeated exposure.
Skin corrosion, Category 1B H314: Causes severe skin burns and eye damage.
Respiratory sensitization, Category 1 H334: May cause allergy or asthma symptoms or
breathing difficulties if inhaled.
Skin sensitization, Category 1 H317: May cause an allergic skin reaction.
Acute aquatic toxicity, Category 1 H400: Very toxic to aquatic life.
Chronic aquatic toxicity, Category 1 H410: Very toxic to aquatic life with long lasting
effects.
EC Classification
Carc.Cat.2; R45
Mut.Cat.2; R46
Repr.Cat.2; R60 - 61
O; R8
Xn; R21
T+; R26
T; R25 - 48/23
C; R34
R42/43
N; R50/53
For the full text of the R-phrases mentioned in this Section, see Section 16.

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Page 1 of 10
Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 104864

Product name: Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

3. Composition/information on ingredients
Formula K₂Cr₂O₇ Cr₂K₂O₇ (Hill)
CAS-No. 7778-50-9
Index-No. 024-002-00-6
EC-No. 231-906-6
Molar mass 294,19 g/mol

4. First aid measures

General advice
First aider needs to protect himself.
After inhalation: fresh air. If breathing stops: immediately apply mechanical ventilation, if
necessary oxygen mask. Immediately call in physician.
After skin contact: wash off with plenty of water. Remove contaminated clothing. Call a physician
immediately.
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist.
If swallowed: give water to drink (two glasses at the most). Seek medical advice immediately. In
exceptional cases only, if medical care is not available within one hour, induce vomiting (only in
persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a
10% slurry) and consult a doctor as quickly as possible.

Notes to physician
Treatment
Carefully clean wounds and cover with sterile dressing material.

5. Fire-fighting measures

Suitable extinguishing media

Use extinguishing measures that are appropriate to local circumstances and the surrounding
environment.
Specific hazards during fire fighting
Not combustible.
Has a fire-promoting effect due to release of oxygen.
Special protective equipment for fire-fighters
Do not stay in dangerous zone without self-contained breathing apparatus. In order to
avoid contact with skin, keep a safety distance and wear suitable protective clothing.
Further information
Prevent fire extinguishing water from contaminating surface water or the ground water system.

6. Accidental release measures

Personal precautions
Avoid inhalation of dusts in all circumstances. Avoid substance contact. Ensure adequate
ventilation.
Environmental precautions
Do not empty into drains.
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Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 104864

Product name: Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Methods for cleaning up

Take up carefully. Forward for disposal. Clean up affected area. Avoid generation of dusts.

7. Handling and storage

Handling
Advice on safe handling
Work under hood. Do not inhale substance.
Observe label precautions.

Storage
Further information on storage conditions
Tightly closed. Dry. Away from combustible materials and sources of ignition and heat. Keep
locked up or in an area accessible only to qualified or authorised persons.
Store at +5°C to +30°C.

8. Exposure controls/personal protection

Personal protective equipment

Protective clothing should be selected specifically for the working place, depending on
concentration and quantity of the hazardous substances handled. The resistance of the
protective clothing to chemicals should be ascertained with the respective supplier.
Respiratory protection
required when dusts are generated.
Recommended Filter type: Filter P 3 (acc. to DIN 3181) for solid and liquid particles of toxic
and very toxic substances
Hand protection
full contact:
Glove material: Nitrile rubber
Glove thickness: 0,11 mm
Break through time: > 480 min
splash contact:
Glove material: Nitrile rubber
Glove thickness: 0,11 mm
Break through time: > 480 min
The protective gloves to be used must comply with the specifications of EC irective 89/686/EEC
and he resultant standard EN374, for example. KCL 741 Dermatril® L (full contact), KCL 741
Dermatril® L (splash contact).
The breakthrough times stated above were determined by KCL in laboratory tests acc. to
EN374 with samples of the recommended glove types.
This recommendation applies only to the product stated in the safety data sheet and supplied by
us as well as to the purpose specified by us. When dissolving in or mixing with other substances
and under conditions deviating from those stated in EN374 please contact the supplier of CE-
approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Eye protection
Tightly fitting safety goggles
Protective measures
Protective suit

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Page 3 of 10
Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 104864

Product name: Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Hygiene measures
Immediately change contaminated clothing. Apply skin- protective barrier cream. Wash hands
and face after working with substance. Work under hood. Do not inhale substance.

9. Physical and chemical properties

Form solid

Colour orange

Odour odourless

pH 3,6
at 100 g/l

Viscosity, dynamic no data available

Melting point 398 °C

Boiling point/boiling range > 500 °C

at 1.013 hPa

Ignition temperature not applicable

Flash point not applicable

Oxidizing properties May intensify fire; oxidiser.

Flammability no data available

Lower explosion limit not applicable

Upper explosion limit not applicable

Vapour pressure not applicable

Relative vapour density no data available

Density 2,69 g/cm3

at 20 °C

Bulk density 1.250 kg/m3

Solubility/qualitative no data available

Water solubility 130 g/l

at 20 °C

Partition coefficient: n- no data available

octanol/water
Evaporation rate no data available

The Safety Data Sheets for catalog items are also available at www.merck-chemicals.com
Page 4 of 10
Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 104864

Product name: Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

10. Stability and reactivity

Conditions to avoid
Strong heating.
Materials to avoid
Risk of explosion with:
Iron, magnesium, hydrazine and derivatives, hydroxylamine, organic combustible substances
Exothermic reaction with:
Boron, anhydrides, Reducing agents, phosphides
A risk of explosion and/or of toxic gas formation exists with the folllowing substances:
organic combustible substances, glycerol, Sulphides, Acetone, conc. sulfuric acid
Hazardous decomposition products
no information available
Thermal decomposition
ca.500 °C

11. Toxicological information

Acute oral toxicity
LD50 rat
Dose: 25 mg/kg
(RTECS)
Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation
of the oesophagus and the stomach.
absorption

Acute inhalation toxicity

LC50 rat
Dose: 0,094 mg/l, 4 h
(IUCLID)
Symptoms: mucosal irritations, Cough, Shortness of breath, absorption, Possible damages:,
damage of respiratory tract
Acute dermal toxicity
LD50 rat
Dose: 1.170 mg/kg
(IUCLID)

absorption

Skin irritation
Causes severe burns.
Eye irritation
Causes serious eye damage. Risk of blindness!

The Safety Data Sheets for catalog items are also available at www.merck-chemicals.com
Page 5 of 10
Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 104864

Product name: Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Sensitisation
Sensitisation test (Magnusson and Kligman):
Result: positive
(IUCLID)
Patch test: human
Result: positive
(IUCLID)
May cause an allergic skin reaction.
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Specific target organ toxicity - repeated exposure
Causes damage to organs through prolonged or repeated exposure.

CMR effects
Carcinogenicity:
May cause cancer.
Mutagenicity:
May cause genetic defects.
Teratogenicity:
May damage the unborn child.
Reproductive toxicity:
May damage fertility.

Further information
Chromium (VI) is highly toxic. It is absorbed via both the lungs as well as the
gastrointestinal tract. Being strong oxidants, chromates/ bichromates can cause burns and
ulcerations on the skin and mucous membranes and also irritations in the upper respiratory
tract. Poor tendency for ulcers to heal following penetration of substance into the wound. In
predisposed persons the substance rapidly leads to sensitization and allergic reactions of
the respiratory tract (risk of pneumonia!) and damage to nasal mucous membranes (under
given circumstances perforation of the septum). After swallowing severe symptoms in the
gastrointestinal tract such as bloody diarrhoea, vomiting (aspiration pneumonia!) spasms,
circulatory collapse, unconsciousness, formation of methaemoglobin. Absorption may result
in hepatic and renal damage. Inhalable chromium(VI) compounds have clearly shown
themselves to be carcinogenic in animal experiments. Lethal dose (man): 0.5 g. Antidotes:
chelating agents such as EDTA, DMPS (Demaval(R)).
Further data:
This substance should be handled with particular care.

12. Ecological information

Ecotoxicity
Toxicity to fish
LC50
Species: Pimephales promelas (fathead minnow)
Dose: 26,13 mg/l
Exposure time: 96 h
(IUCLID)

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Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 104864

Product name: Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Toxicity to daphnia and other aquatic invertebrates.

EC50
Species: Daphnia magna (Water flea)
Dose: 0,77 mg/l
Exposure time: 48 h
(in soft water) (IUCLID)
Toxicity to algae
IC50
Species: Chlorella vulgaris (Fresh water algae)
Dose: 0,16 - 0,59 mg/l
Exposure time: 96 h
(IUCLID)
Toxicity to bacteria
MICROTOX-TEST EC50
Species: Photobacterium phosphoreum
Dose: 58 mg/l
Exposure time: 30 min

Persistence and degradability

Biodegradability
The methods for determining the biological degradability are not applicable to inorganic
substances.
Additional ecological information
Do not allow to enter waters, waste water, or soil!

13. Disposal considerations

Product
Chemicals must be disposed of in compliance with the respective national regulations. Under
www.retrologistik.de you will find country- and substance-specific information as well as contact
partners.
Packaging
Merck product packaging must be disposed of in compliance with the country-specific
regulations or must be passed to a packaging return system. Under www.retrologistik.de you will
find special information on the respective national conditions as well as contact partners.

14. Transport information

ADR/RID
UN 3086 TOXIC SOLID, OXIDIZING, N.O.S. (POTASSIUM DICHROMATE), 6.1 (5.1), II
IATA
UN 3086 TOXIC SOLID, OXIDIZING, N.O.S. (POTASSIUM DICHROMATE), 6.1 (5.1), II
IMDG
UN 3086 TOXIC SOLID, OXIDIZING, N.O.S. (POTASSIUM DICHROMATE), 6.1 (5.1), II
EmS F-A S-Q
The transport regulations re cited according to international regulations and in the form applicable
in Germany. Possible national deviations in other countries are not considered.

The Safety Data Sheets for catalog items are also available at www.merck-chemicals.com
Page 7 of 10
Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 104864

Product name: Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

15. Regulatory information

GHS-Labelling
Hazard pictograms

Signal word
Danger

Hazard statements
H350: May cause cancer.
H340: May cause genetic defects.
H360FD: May damage fertility. May damage the unborn child.
H272: May intensify fire; oxidiser.
H330: Fatal if inhaled.
H301: Toxic if swallowed.
H312: Harmful in contact with skin.
H372: Causes damage to organs through prolonged or repeated exposure.
H314: Causes severe skin burns and eye damage.
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H317: May cause an allergic skin reaction.
H410: Very toxic to aquatic life with long lasting effects.

Precautionary statements
P201: Obtain special instructions before use.
P280: Wear protective gloves.
P301 + P330 + P331: IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P304 + P341: IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a
position comfortable for breathing.
P308 + P313: IF exposed or concerned: Get medical advice/attention.

Reduced labelling (≤125 ml)

Hazard pictograms

Signal word
Danger

Hazard statements
H350: May cause cancer.
H340: May cause genetic defects.
H360FD: May damage fertility. May damage the unborn child.
H330: Fatal if inhaled.
H301: Toxic if swallowed.
H372: Causes damage to organs through prolonged or repeated exposure.
H314: Causes severe skin burns and eye damage.
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H317: May cause an allergic skin reaction.

Precautionary statements
The Safety Data Sheets for catalog items are also available at www.merck-chemicals.com
Page 8 of 10
Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 104864

Product name: Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

P201: Obtain special instructions before use.

P280: Wear protective gloves.
P301 + P330 + P331: IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if
present and easy to do. Continue rinsing.
P304 + P341: IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position
comfortable for breathing.
P308 + P313: IF exposed or concerned: Get medical advice/attention.

Index-No. 024-002-00-6
Labelling according to EC Directives
Symbol(s): T+ Very toxic
N Dangerous for the environment
O Oxidising
R-phrase(s): 45-46-60-61-8-21- May cause cancer. May cause heritable genetic
25-26-34-42/43- damage. May impair fertility. May cause harm to the
48/23-50/53 unborn child. Contact with combustible material may
cause fire. Also harmful in contact with skin. Also toxic if
swallowed. Also very toxic by inhalation. Causes burns.
May cause sensitization by inhalation and skin contact.
Also toxic: danger of serious damage to health by
prolonged exposure through inhalation. Very toxic to
aquatic organisms, may cause long-term adverse
effects in the aquatic environment.
S-phrase(s): 53-45-60-61 Avoid exposure - obtain special instructions before use.
In case of accident or if you feel unwell, seek medical
advice immediately (show the label where possible).
This material and its container must be disposed of as
hazardous waste. Avoid release to the environment.
Refer to special instructions/ Safety data sheets.
EC-No. 231-906-6 EC Label
Reduced labelling (≤125 ml)
Symbol(s): T+ Very toxic
N Dangerous for the environment
O Oxidising
R-phrase(s): 45-46-60-61-21-25-26- May cause cancer. May cause heritable genetic damage. May impair
34-42/43-48/23 fertility. May cause harm to the unborn child. Also harmful in contact
with skin. Also toxic if swallowed. Also very toxic by inhalation.
Causes burns. May cause sensitization by inhalation and skin contact.
Also toxic: danger of serious damage to health by prolonged exposure
through inhalation.
S-phrase(s): 53-45 Avoid exposure - obtain special instructions before use. In case of
accident or if you feel unwell, seek medical advice immediately (show
the label where possible).

National legislation
Storage class VCI: 5.1 B Oxidizing agents (TRG 515 Group 2+3)
Major Accident Hazard 96/82/EC Update: 2003
Legislation: Very toxic
1
Quantity 1: 5 t
Quantity 2: 20 t

The Safety Data Sheets for catalog items are also available at www.merck-chemicals.com
Page 9 of 10
Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 104864

Product name: Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

96/82/EC Update: 2003

Oxidising
3
Quantity 1: 50 t
Quantity 2: 200 t
96/82/EC Update: 2003
Dangerous for the environment
9a
Quantity 1: 100 t
Quantity 2: 200 t
Other regulations: Take note of Dir 94/33/EC on the protection of young people at
work. Take note of Dir 92/85/EEC on the safety and health at work
of pregnant workers.

16. Other information

Full text of R-phrases referred to under sections 2 and 3
R8 Contact with combustible material may cause fire.
R21 Harmful in contact with skin.
R25 Toxic if swallowed.
R26 Very toxic by inhalation.
R34 Causes burns.
R42/43 May cause sensitization by inhalation and skin contact.
R45 May cause cancer.
R46 May cause heritable genetic damage.
R48/23 Toxic: danger of serious damage to health by prolonged exposure
through inhalation.
R50/53 Very toxic to aquatic organisms, may cause long-term adverse
effects in the aquatic environment.
R60 May impair fertility.
R61 May cause harm to the unborn child.

Regional representation: This information is given on the authorised Safety Data Sheet for
your country.

The information contained herein is based on the present state of our knowledge. It characterizes the product with
regard to the appropriate safety precautions. It does not represent a guarantee of the properties of the product.

The Safety Data Sheets for catalog items are also available at www.merck-chemicals.com
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