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Practice Test—Cell Division, Molecular Genetics and Natural Selection

Name: ____________________ ( ) Class: 4F / 4H


35
Answer all questions.

1 The following drawing was made of a cell undergoing mitosis.

a In which stage of mitosis is the cell shown in this drawing? [1]

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b Describe one piece of evidence, visible in the drawing, which could be used to confirm
that this cell is not in the first division of meiosis. [1]

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[Total = 2 marks]

2 In the table below, compare the processes of mitosis and meiosis. [6]

Mitosis Meiosis
Number of cytoplasmic divisions

Number of daughter cells


produced

Number of chromosomes in
daughter cells

Crossing over of homologous


chromosomes?
(Write yes / no) If yes, name the
stage in which this occurs.
Separation of Sister Chromatids?
(Write yes / no) If yes, name the
stage in which this occurs.

Function

[Total = 6 marks]
Practice Test—Cell Division, Molecular Genetics and Natural Selection

Name: ____________________ ( ) Class: 4F / 4H

3a In the space below, draw a diagram to illustrate the basic structure of a nucleotide.
Label all parts of the nucleotide you have drawn. [3]

b 38% of the bases in a DNA molecule was found to be Thymine. Write down the
percentages of Adenine, Cytosine and Guanine in the space provided below. [3]

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c During DNA replication, an error occurred, resulting in a change in one of the


nucleotide bases of the DNA molecule. What is the word that best describes this
change? [1]

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[Total = 7 marks]
Practice Test—Cell Division, Molecular Genetics and Natural Selection

Name: ____________________ ( ) Class: 4F / 4H

4 The diagrams below show normal red blood cells and sickle red blood cells in
humans.

normal red blood cells

sickle red blood cells

Normal red blood cells contain normal haemoglobin A controlled by the allele HbA. A
mutant allele HbS makes a slightly different haemoglobin S. If a person is homozygous
(HbsHbs), the person suffers from sickle cell anaemia.

a What is the main function of red blood cells? [1]

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b Suggest one disadvantage for people having sickle red blood cells. Explain your
answer. [2]

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c A man with sickle cell anaemia (heterozygous condition) has a child with this disease.
What might be the genotype of his wife who does not have the disease? Explain your
answer without a genetic diagram. [2]

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Practice Test—Cell Division, Molecular Genetics and Natural Selection

Name: ____________________ ( ) Class: 4F / 4H

d Is it possible for the couple to have children who do not have the disease?
(Explain your answer with a genetic diagram.) [3]

[Total = 8 marks (SMSS)]

5 The diagram shows the chromosomes of the foetus formed after fertilization.

a Is the foetus a boy or a girl? Support your answer with information from the diagram. [2]
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Practice Test—Cell Division, Molecular Genetics and Natural Selection

Name: ____________________ ( ) Class: 4F / 4H

b What abnormality can be detected from the diagram? [1]

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c What causes this abnormality? [1]

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d Explain how the process of meiosis can lead to this abnormality. [3]

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[Total = 7 marks]
Practice Test—Cell Division, Molecular Genetics and Natural Selection

Name: ____________________ ( ) Class: 4F / 4H

6 Industrial Melanism is a term used to describe the adaptation of a population in


response to pollution. One example of this occurred in populations of peppered moths
in the area of Manchester, England from 1845 to 1890.

Before the industrial revolution, the trunks of the trees in the forest around
Manchester were light grayish-green due to the presence of lichens. Most of the
peppered moths in the area were light colored with dark spots. As the industrial
revolution progressed, the tree trunks became covered with soot and turned dark.

Over a period of 45 years, the dark variety of the peppered moth became more
common than the light coloured variety. Explain how this change could have occurred. [5]

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[Total = 5 marks]