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Endocrinology at a glance

Early diagnosis for endocrine disorder

The generic term thyrotoxicosis refers to the clinical syndrome in which serum
total and free triiodothyronine (T3) or free thyroxine (T4) concentrations or both
are elevated and the peripheral tissues are hypermetabolic, irrespective of the
source of the excess hormones. Hyperthyroidism is one cause of thyrotoxicosis
and is defined as increased endogenous thyroid hormone synthesis and release.
Another cause of thyrotoxicosis is excess outpouring of hormone from a damaged
thyroid in the absence of excess production, including the various causes
of thyroiditis. A third cause is excess thyroid hormone ingestion. Subclinical
thyrotoxicosis is defined as the presence of a low serum TSH level with normal
total and free T3 and T4 concentrations.