Вы находитесь на странице: 1из 13

The clock drawing test as a screening

tool in mild cognitive impairment and


very mild dementia: a new brief
method of scoring and normative data
in the elderly
Neurological Sciences

June 2016, Volume 37, Issue 6, pp 867–873 | Cite as

Original Article
First Online: 10 February 2016

2 Shares
1.2k Downloads
9 Citations

Abstract

many studies sustained that the clock drawing test (CDT) was not able to
accurately detect people with CDR = 0.5. Other researchers have promoted the
use of scoring approaches with multiple scales that rate quantitative and
qualitative features of the production. Nevertheless, these scoring systems are
complex and time-consuming. We propose a new brief CDT’ scoring system in
order to find a good measure for mild cognitive decline which is at the same time
easy to administer. we enrolled 719 subjects: n. 181 with mild Alzheimer’s disease
(AD); n. 200 with amnesic mild cognitive impairment (MCI) and n. 338 healthy
elderly subjects (C). our CDT-three-cluster scoring system demonstrated a good
sensitivity and an excellent specificity to discriminate MCI subjects from normal
elderly (76 and 84 %, respectively) and an excellent sensitivity and specificity to
discriminate patients affected by mild Alzheimer disease (CDR: 1) from normal
elderly (91 and 90 %, respectively). We found that CDT’ score = 1.30 discriminate
people with MCI, whereas a score = 4.38 discriminate AD patients. The three-
cluster-scoring-system demonstrated a good diagnostic accuracy, taking into
account those error-items more predictive of cognitive decline: omission of
numbers or hands, writing numbers or hands in a wrong position and writing
numbers or hands in a different code. Our CDT’ scoring system is very short and
easy method which can be used also by non-specialist.

Keywords
mild Alzheimer’s disease mild cognitive impairment clock drawing test
scoring system
Electronic supplementary material
The online version of this article (doi: 10.1007/s10072-016-2480-6
(https://doi.org/10.1007/s10072-016-2480-6)) contains supplementary
material, which is available to authorized users.

This is a preview of subscription content, log in to check access.

Notes

Compliance with ethical standards

Conflict of interest

The authors report no conflict of interests.

Supplementary material
10072_2016_2480_MOESM1_ESM.docx (17 kb)
Supplementary material 1 (DOCX 16 kb)

References
1. Shulman KI, Pushkar Gold D, Cohen CA, Zucchero CA (1993) Clock-
drawing and dementia in the community: A longitudinal study. Int J
Geriatr Psychiatry 8:487–496
CrossRef (https://doi.org/10.1002/gps.930080606)
Google Scholar (http://scholar.google.com/scholar_lookup?title=Clock-
drawing%20and%20dementia%20in%20the%20community%3A%20A%2
0longitudinal%20study&author=KI.%20Shulman&author=D.%20Pushkar
%20Gold&author=CA.%20Cohen&author=CA.%20Zucchero&journal=Int
%20J%20Geriatr%20Psychiatry&volume=8&pages=487-
496&publication_year=1993)
2. Ferrucci L, Cecchi F, Guralnik JM, Giampaoli S, Lo Noce C, Salani B,
Bandinelli S, Baroni A 1996 Does the Clock Drawing Test predict cognitive
decline in older persons independent of the Mini-Mental State
Examination? The FINE Study Group. Finland, Italy, The Netherlands
Elderly. J Am Geriatr Soc 44:1326–1331
Google Scholar (https://scholar.google.com/scholar?
q=Ferrucci%20L%2C%20Cecchi%20F%2C%20Guralnik%20JM%2C%20G
iampaoli%20S%2C%20Lo%20Noce%20C%2C%20Salani%20B%2C%20Ba
ndinelli%20S%2C%20Baroni%20A%201996%20Does%20the%20Clock%2
0Drawing%20Test%20predict%20cognitive%20decline%20in%20older%2
0persons%20independent%20of%20the%20Mini-
Mental%20State%20Examination%3F%20The%20FINE%20Study%20Gr
oup.%20Finland%2C%20Italy%2C%20The%20Netherlands%20Elderly.%
20J%20Am%20Geriatr%20Soc%2044%3A1326%E2%80%931331)
3. Shulman KI (2000) Clock-drawing: is it the ideal cognitive screening test?
Int J Geriatr Psychiatry 15:548–561
CrossRef (https://doi.org/10.1002/1099-
1166(200006)15%3A6<548%3A%3AAID-GPS242>3.0.CO%3B2-U)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10861923)
Google Scholar (http://scholar.google.com/scholar_lookup?title=Clock-
drawing%3A%20is%20it%20the%20ideal%20cognitive%20screening%20t
est%3F&author=KI.%20Shulman&journal=Int%20J%20Geriatr%20Psych
iatry&volume=15&pages=548-561&publication_year=2000)
4. Libon DJ, Malamut BL, Swenson R, Sands LP, Cloud BS (1996) Further
analyses of clock drawings among demented and nondemented older
subjects. Arch Clin Neuropsychol 11:193–205
CrossRef (https://doi.org/10.1016/0887-6177(95)00026-7)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14588923)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Further%20analyses%20of%20clock%20drawings%20among%20de
mented%20and%20nondemented%20older%20subjects&author=DJ.%20
Libon&author=BL.%20Malamut&author=R.%20Swenson&author=LP.%2
0Sands&author=BS.%20Cloud&journal=Arch%20Clin%20Neuropsychol&
volume=11&pages=193-205&publication_year=1996)
5. Mendez MF, Ala T, Underwood KL (1992) Development of scoring criteria
for the clock drawing task in Alzheimer’s disease. J Am Geriatr Soc
40:1095–1099
CrossRef (https://doi.org/10.1111/j.1532-5415.1992.tb01796.x)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=1401692)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Development%20of%20scoring%20criteria%20for%20the%20clock
%20drawing%20task%20in%20Alzheimer%E2%80%99s%20disease&auth
or=MF.%20Mendez&author=T.%20Ala&author=KL.%20Underwood&jour
nal=J%20Am%20Geriatr%20Soc&volume=40&pages=1095-
1099&publication_year=1992)
6. Rouleau I, Salmon DP, Butters N, Kennedy C, McGuire K (1992)
Quantitative and qualitative analyses of clock drawings in Alzheimer’s and
Huntington’s disease. Brain Cogn 18:70–87
CrossRef (https://doi.org/10.1016/0278-2626(92)90112-Y)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=1543577)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Quantitative%20and%20qualitative%20analyses%20of%20clock%20
drawings%20in%20Alzheimer%E2%80%99s%20and%20Huntington%E2
%80%99s%20disease&author=I.%20Rouleau&author=DP.%20Salmon&a
uthor=N.%20Butters&author=C.%20Kennedy&author=K.%20McGuire&jo
urnal=Brain%20Cogn&volume=18&pages=70-
87&publication_year=1992)
7. Sunderland T, Hill JL, Mellow AM, Lawlor BA, Gundersheimer J,
Newhouse PA, Grafman JH (1989) Clock drawing in Alzheimer’s disease. A
novel measure of dementia severity. J Am Geriatr Soc 37:725–729
CrossRef (https://doi.org/10.1111/j.1532-5415.1989.tb02233.x)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=2754157)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Clock%20drawing%20in%20Alzheimer%E2%80%99s%20disease.%2
0A%20novel%20measure%20of%20dementia%20severity&author=T.%20
Sunderland&author=JL.%20Hill&author=AM.%20Mellow&author=BA.%
20Lawlor&author=J.%20Gundersheimer&author=PA.%20Newhouse&aut
hor=JH.%20Grafman&journal=J%20Am%20Geriatr%20Soc&volume=37
&pages=725-729&publication_year=1989)
8. Tuokko H, Hadjistavropoulos T, Miller JA, Beattie BL (1992) The Clock
Test: a sensitive measure to differentiate normal elderly from those with
Alzheimer disease. J Am Geriatr Soc 40:579–584
CrossRef (https://doi.org/10.1111/j.1532-5415.1992.tb02106.x)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=1587974)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=The%20Clock%20Test%3A%20a%20sensitive%20measure%20to%2
0differentiate%20normal%20elderly%20from%20those%20with%20Alzh
eimer%20disease&author=H.%20Tuokko&author=T.%20Hadjistavropoul
os&author=JA.%20Miller&author=BL.%20Beattie&journal=J%20Am%20
Geriatr%20Soc&volume=40&pages=579-584&publication_year=1992)
9. Cahn DA, Salmon DP, Monsch AU, Butters N, Wiederholt WC, Corey-
Bloom J, Barrett-Connor E (1996) Screening for dementia of the alzheimer
type in the community: the utility of the Clock Drawing Test. Arch Clin
Neuropsychol 11:529–539
CrossRef (https://doi.org/10.1016/0887-6177(95)00041-0)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14588458)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Screening%20for%20dementia%20of%20the%20alzheimer%20type
%20in%20the%20community%3A%20the%20utility%20of%20the%20Clo
ck%20Drawing%20Test&author=DA.%20Cahn&author=DP.%20Salmon&
author=AU.%20Monsch&author=N.%20Butters&author=WC.%20Wieder
holt&author=J.%20Corey-Bloom&author=E.%20Barrett-
Connor&journal=Arch%20Clin%20Neuropsychol&volume=11&pages=529
-539&publication_year=1996)
10. Borson S, Scanlan J, Brush M, Vitaliano P, Dokmak A (2000) The mini-
cog: a cognitive ‘vital signs’ measure for dementia screening in multi-
lingual elderly. Int J Geriatr Psychiatry 15:1021–1027
CrossRef (https://doi.org/10.1002/1099-
1166(200011)15%3A11<1021%3A%3AAID-GPS234>3.0.CO%3B2-6)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11113982)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=The%20mini-
cog%3A%20a%20cognitive%20%E2%80%98vital%20signs%E2%80%99%
20measure%20for%20dementia%20screening%20in%20multi-
lingual%20elderly&author=S.%20Borson&author=J.%20Scanlan&author
=M.%20Brush&author=P.%20Vitaliano&author=A.%20Dokmak&journal
=Int%20J%20Geriatr%20Psychiatry&volume=15&pages=1021-
1027&publication_year=2000)
11. Scanlan JM, Brush M, Quijano C, Borson S (2002) Comparing clock tests
for dementia screening: naive judgments vs formal systems–what is
optimal? Int J Geriatr Psychiatry 17:14–21
CrossRef (https://doi.org/10.1002/gps.516)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11802225)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Comparing%20clock%20tests%20for%20dementia%20screening%3
A%20naive%20judgments%20vs%20formal%20systems%E2%80%93wha
t%20is%20optimal%3F&author=JM.%20Scanlan&author=M.%20Brush&
author=C.%20Quijano&author=S.%20Borson&journal=Int%20J%20Geria
tr%20Psychiatry&volume=17&pages=14-21&publication_year=2002)
12. Freund B, Gravenstein S, Ferris R, Burke BL, Shaheen E (2005) Drawing
clocks and driving cars. J Gen Intern Med 20:240–244
CrossRef (https://doi.org/10.1111/j.1525-1497.2005.40069.x)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15836527)
PubMedCentral
(http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1490081)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Drawing%20clocks%20and%20driving%20cars&author=B.%20Freu
nd&author=S.%20Gravenstein&author=R.%20Ferris&author=BL.%20Bur
ke&author=E.%20Shaheen&journal=J%20Gen%20Intern%20Med&volum
e=20&pages=240-244&publication_year=2005)
13. Shulman KI, Herrmann N, Brodaty H, Chiu H, Lawlor B, Ritchie K,
Scanlan JM (2006) IPA survey of brief cognitive screening instruments.
Int Psychogeriatr 18:281–294
CrossRef (https://doi.org/10.1017/S1041610205002693)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16466586)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=IPA%20survey%20of%20brief%20cognitive%20screening%20instru
ments&author=KI.%20Shulman&author=N.%20Herrmann&author=H.%2
0Brodaty&author=H.%20Chiu&author=B.%20Lawlor&author=K.%20Ritc
hie&author=JM.%20Scanlan&journal=Int%20Psychogeriatr&volume=18&
pages=281-294&publication_year=2006)
14. Ben-Yehuda A, Bentur N, Friedman G (1995) The clock drawing test as a
cognitive screening tool for elderly patients in an acute-care hospital.
Aging (Milano) 7:188–190
Google Scholar (http://scholar.google.com/scholar_lookup?
title=The%20clock%20drawing%20test%20as%20a%20cognitive%20scre
ening%20tool%20for%20elderly%20patients%20in%20an%20acute-
care%20hospital&author=A.%20Ben-
Yehuda&author=N.%20Bentur&author=G.%20Friedman&journal=Aging
%20%28Milano%29&volume=7&pages=188-190&publication_year=1995)
15. Brodaty H, Moore CM (1997) The clock drawing test for dementia of the
Alzheimer’s type: a comparison of three scoring methods in a memory
disorders clinic. Int J Geriatr Psychiatry 12:619–627
CrossRef (https://doi.org/10.1002/(SICI)1099-
1166(199706)12%3A6<619%3A%3AAID-GPS554>3.0.CO%3B2-H)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9215942)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=The%20clock%20drawing%20test%20for%20dementia%20of%20th
e%20Alzheimer%E2%80%99s%20type%3A%20a%20comparison%20of%
20three%20scoring%20methods%20in%20a%20memory%20disorders%2
0clinic&author=H.%20Brodaty&author=CM.%20Moore&journal=Int%20
J%20Geriatr%20Psychiatry&volume=12&pages=619-
627&publication_year=1997)
16. Lam LCW, Chiu HFK, Ng KO, Chan C, Chan WF, Li SW, Wong M (1998)
Clock-face drawing, reading and setting tests in the screening of dementia
in chinese elderly adults. J Gerontol Series B Psychol Sci Social Sci
53B:P353–P357
CrossRef (https://doi.org/10.1093/geronb/53B.6.P353)
Google Scholar (http://scholar.google.com/scholar_lookup?title=Clock-
face%20drawing%2C%20reading%20and%20setting%20tests%20in%20t
he%20screening%20of%20dementia%20in%20chinese%20elderly%20adu
lts&author=LCW.%20Lam&author=HFK.%20Chiu&author=KO.%20Ng&a
uthor=C.%20Chan&author=WF.%20Chan&author=SW.%20Li&author=M
.%20Wong&journal=J%20Gerontol%20Series%20B%20Psychol%20Sci%
20Social%20Sci&volume=53B&pages=P353-
P357&publication_year=1998)
17. Watson YI, Arfken CL, Birge SJ (1993) Clock completion: an objective
screening test for dementia. J Am Geriatr Soc 41:1235–1240
CrossRef (https://doi.org/10.1111/j.1532-5415.1993.tb07308.x)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8227899)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Clock%20completion%3A%20an%20objective%20screening%20test
%20for%20dementia&author=YI.%20Watson&author=CL.%20Arfken&au
thor=SJ.%20Birge&journal=J%20Am%20Geriatr%20Soc&volume=41&pa
ges=1235-1240&publication_year=1993)
18. Wolf-Klein GP, Silverstone FA, Levy AP, Brod MS (1989) Screening for
Alzheimer’s disease by clock drawing. J Am Geriatr Soc 37:730–734
CrossRef (https://doi.org/10.1111/j.1532-5415.1989.tb02234.x)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=2754158)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Screening%20for%20Alzheimer%E2%80%99s%20disease%20by%2
0clock%20drawing&author=GP.%20Wolf-
Klein&author=FA.%20Silverstone&author=AP.%20Levy&author=MS.%20
Brod&journal=J%20Am%20Geriatr%20Soc&volume=37&pages=730-
734&publication_year=1989)
19. Chiu YC, Li CL, Lin KN, Chiu YF, Liu HC (2008) Sensitivity and specificity
of the Clock Drawing Test, incorporating Rouleau scoring system, as a
screening instrument for questionable and mild dementia: scale
development. Int J Nurs Stud 45:75–84
CrossRef (https://doi.org/10.1016/j.ijnurstu.2006.09.005)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17123533)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Sensitivity%20and%20specificity%20of%20the%20Clock%20Drawin
g%20Test%2C%20incorporating%20Rouleau%20scoring%20system%2C
%20as%20a%20screening%20instrument%20for%20questionable%20and
%20mild%20dementia%3A%20scale%20development&author=YC.%20Ch
iu&author=CL.%20Li&author=KN.%20Lin&author=YF.%20Chiu&author
=HC.%20Liu&journal=Int%20J%20Nurs%20Stud&volume=45&pages=75
-84&publication_year=2008)
20. Seigerschmidt E, Mosch E, Siemen M, Forstl H, Bickel H (2002) The clock
drawing test and questionable dementia: reliability and validity. Int J
Geriatr Psychiatry 17:1048–1054
CrossRef (https://doi.org/10.1002/gps.747)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12404654)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=The%20clock%20drawing%20test%20and%20questionable%20dem
entia%3A%20reliability%20and%20validity&author=E.%20Seigerschmidt
&author=E.%20Mosch&author=M.%20Siemen&author=H.%20Forstl&aut
hor=H.%20Bickel&journal=Int%20J%20Geriatr%20Psychiatry&volume=1
7&pages=1048-1054&publication_year=2002)
21. Paganini-Hill A, Clark LJ (2007) Preliminary assessment of cognitive
function in older adults by clock drawing, box copying and narrative
writing. Dement Geriatr Cogn Disord 23:74–81
CrossRef (https://doi.org/10.1159/000097097)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17114883)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Preliminary%20assessment%20of%20cognitive%20function%20in%
20older%20adults%20by%20clock%20drawing%2C%20box%20copying%
20and%20narrative%20writing&author=A.%20Paganini-
Hill&author=LJ.%20Clark&journal=Dement%20Geriatr%20Cogn%20Dis
ord&volume=23&pages=74-81&publication_year=2007)
22. von Gunten A, Ostos-Wiechetek M, Brull J, Vaudaux-Pisquem I, Cattin S,
Duc R (2008) Clock-drawing test performance in the normal elderly and
its dependence on age and education. Eur Neurol 60:73–78
CrossRef (https://doi.org/10.1159/000131895)
Google Scholar (http://scholar.google.com/scholar_lookup?title=Clock-
drawing%20test%20performance%20in%20the%20normal%20elderly%2
0and%20its%20dependence%20on%20age%20and%20education&author
=A.%20Gunten&author=M.%20Ostos-
Wiechetek&author=J.%20Brull&author=I.%20Vaudaux-
Pisquem&author=S.%20Cattin&author=R.%20Duc&journal=Eur%20Neur
ol&volume=60&pages=73-78&publication_year=2008)
23. Hubbard EJ, Santini V, Blankevoort CG, Volkers KM, Barrup MS, Byerly L,
Chaisson C, Jefferson AL, Kaplan E, Green RC, Stern RA (2008) Clock
drawing performance in cognitively normal elderly. Arch Clin
Neuropsychol 23:295–327
CrossRef (https://doi.org/10.1016/j.acn.2007.12.003)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18243644)
PubMedCentral
(http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752157)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Clock%20drawing%20performance%20in%20cognitively%20normal
%20elderly&author=EJ.%20Hubbard&author=V.%20Santini&author=CG.
%20Blankevoort&author=KM.%20Volkers&author=MS.%20Barrup&auth
or=L.%20Byerly&author=C.%20Chaisson&author=AL.%20Jefferson&auth
or=E.%20Kaplan&author=RC.%20Green&author=RA.%20Stern&journal=
Arch%20Clin%20Neuropsychol&volume=23&pages=295-
327&publication_year=2008)
24. Pinto E, Peters R (2009) Literature review of the clock drawing test as a
tool for cognitive screening. Dement Geriatr Cogn Disord 27:201–213
CrossRef (https://doi.org/10.1159/000203344)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19225234)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Literature%20review%20of%20the%20clock%20drawing%20test%2
0as%20a%20tool%20for%20cognitive%20screening&author=E.%20Pinto
&author=R.%20Peters&journal=Dement%20Geriatr%20Cogn%20Disord
&volume=27&pages=201-213&publication_year=2009)
25. Ehreke L, Luck T, Luppa M, Konig HH, Villringer A, Riedel-Heller SG
(2011) Clock drawing test—screening utility for mild cognitive impairment
according to different scoring systems: results of the Leipzig Longitudinal
Study of the Aged (LEILA 75 +). Int Psychogeriatr 23:1592–1601
CrossRef (https://doi.org/10.1017/S104161021100144X)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21813037)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Clock%20drawing%20test%E2%80%94screening%20utility%20for%
20mild%20cognitive%20impairment%20according%20to%20different%2
0scoring%20systems%3A%20results%20of%20the%20Leipzig%20Longit
udinal%20Study%20of%20the%20Aged%20%28LEILA%2075%C2%A0%
2B%29&author=L.%20Ehreke&author=T.%20Luck&author=M.%20Luppa
&author=HH.%20Konig&author=A.%20Villringer&author=SG.%20Riedel
-Heller&journal=Int%20Psychogeriatr&volume=23&pages=1592-
1601&publication_year=2011)
26. Parsey CM, Schmitter-Edgecombe M (2011) Quantitative and qualitative
analyses of the clock drawing test in mild cognitive impairment and
Alzheimer disease: evaluation of a modified scoring system. J Geriatr
Psychiatry Neurol 24:108–118
CrossRef (https://doi.org/10.1177/0891988711402349)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21546651)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Quantitative%20and%20qualitative%20analyses%20of%20the%20cl
ock%20drawing%20test%20in%20mild%20cognitive%20impairment%20
and%20Alzheimer%20disease%3A%20evaluation%20of%20a%20modifie
d%20scoring%20system&author=CM.%20Parsey&author=M.%20Schmitt
er-
Edgecombe&journal=J%20Geriatr%20Psychiatry%20Neurol&volume=24
&pages=108-118&publication_year=2011)
27. Morris JC (1993) The Clinical Dementia Rating (CDR): current version and
scoring rules. Neurology 43:2412–2414
CrossRef (https://doi.org/10.1212/WNL.43.11.2412-a)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8232972)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=The%20Clinical%20Dementia%20Rating%20%28CDR%29%3A%20c
urrent%20version%20and%20scoring%20rules&author=JC.%20Morris&j
ournal=Neurology&volume=43&pages=2412-
2414&publication_year=1993)
28. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM
(1984) Clinical diagnosis of Alzheimer’s disease: report of the NINCDS-
ADRDA Work Group under the auspices of Department of Health and
Human Services Task Force on Alzheimer’s Disease. Neurology 34:939–
944
CrossRef (https://doi.org/10.1212/WNL.34.7.939)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=6610841)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Clinical%20diagnosis%20of%20Alzheimer%E2%80%99s%20disease
%3A%20report%20of%20the%20NINCDS-
ADRDA%20Work%20Group%20under%20the%20auspices%20of%20De
partment%20of%20Health%20and%20Human%20Services%20Task%20
Force%20on%20Alzheimer%E2%80%99s%20Disease&author=G.%20Mc
Khann&author=D.%20Drachman&author=M.%20Folstein&author=R.%2
0Katzman&author=D.%20Price&author=EM.%20Stadlan&journal=Neuro
logy&volume=34&pages=939-944&publication_year=1984)
29. Petersen RC, Doody R, Kurz A, Mohs RC, Morris JC, Rabins PV, Ritchie K,
Rossor M, Thal L, Winblad B (2001) Current concepts in mild cognitive
impairment. Arch Neurol 58:1985–1992
CrossRef (https://doi.org/10.1001/archneur.58.12.1985)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11735772)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Current%20concepts%20in%20mild%20cognitive%20impairment&a
uthor=RC.%20Petersen&author=R.%20Doody&author=A.%20Kurz&auth
or=RC.%20Mohs&author=JC.%20Morris&author=PV.%20Rabins&author
=K.%20Ritchie&author=M.%20Rossor&author=L.%20Thal&author=B.%2
0Winblad&journal=Arch%20Neurol&volume=58&pages=1985-
1992&publication_year=2001)
30. Magni E, Binetti G, Bianchetti A, Rozzini R, Trabucchi M (1996) Mini-
mental State Examination: a normative study in italian elderly population.
Eur J Neurol 3:198–202
CrossRef (https://doi.org/10.1111/j.1468-1331.1996.tb00423.x)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21284770)
Google Scholar (http://scholar.google.com/scholar_lookup?title=Mini-
mental%20State%20Examination%3A%20a%20normative%20study%20i
n%20italian%20elderly%20population&author=E.%20Magni&author=G.
%20Binetti&author=A.%20Bianchetti&author=R.%20Rozzini&author=M.
%20Trabucchi&journal=Eur%20J%20Neurol&volume=3&pages=198-
202&publication_year=1996)
31. Lee AY, Kim JS, Choi BH, Sohn EH (2009) Characteristics of clock
drawing test (CDT) errors by the dementia type: quantitative and
qualitative analyses. Arch Gerontol Geriatr 48:58–60
CrossRef (https://doi.org/10.1016/j.archger.2007.10.003)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18037511)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Characteristics%20of%20clock%20drawing%20test%20%28CDT%2
9%20errors%20by%20the%20dementia%20type%3A%20quantitative%20
and%20qualitative%20analyses&author=AY.%20Lee&author=JS.%20Kim
&author=BH.%20Choi&author=EH.%20Sohn&journal=Arch%20Gerontol
%20Geriatr&volume=48&pages=58-60&publication_year=2009)
32. Lessig MC, Scanlan JM, Nazemi H, Borson S (2008) Time that tells:
critical clock-drawing errors for dementia screening. Int Psychogeriatr
20:459–470
CrossRef (https://doi.org/10.1017/S1041610207006035)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17908348)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Time%20that%20tells%3A%20critical%20clock-
drawing%20errors%20for%20dementia%20screening&author=MC.%20Le
ssig&author=JM.%20Scanlan&author=H.%20Nazemi&author=S.%20Bors
on&journal=Int%20Psychogeriatr&volume=20&pages=459-
470&publication_year=2008)
33. Juby A, Tench S, Baker V (2002) The value of clock drawing in identifying
executive cognitive dysfunction in people with a normal Mini-Mental State
Examination score. CMAJ 167:859–864
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12406943)
PubMedCentral
(http://www.ncbi.nlm.nih.gov/pmc/articles/PMC128397)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=The%20value%20of%20clock%20drawing%20in%20identifying%20
executive%20cognitive%20dysfunction%20in%20people%20with%20a%2
0normal%20Mini-
Mental%20State%20Examination%20score&author=A.%20Juby&author=
S.%20Tench&author=V.%20Baker&journal=CMAJ&volume=167&pages=
859-864&publication_year=2002)
34. van der Burg M, Bouwen A, Stessens J, Ylieff M, Fontaine O, de Lepeleire
J, Buntinx F (2004) Scoring clock tests for dementia screening: a
comparison of two scoring methods. Int J Geriatr Psychiatry 19:685–689
CrossRef (https://doi.org/10.1002/gps.1143)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15254925)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Scoring%20clock%20tests%20for%20dementia%20screening%3A%2
0a%20comparison%20of%20two%20scoring%20methods&author=M.%2
0Burg&author=A.%20Bouwen&author=J.%20Stessens&author=M.%20Yli
eff&author=O.%20Fontaine&author=J.%20Lepeleire&author=F.%20Bunt
inx&journal=Int%20J%20Geriatr%20Psychiatry&volume=19&pages=685-
689&publication_year=2004)
35. Samton JB, Ferrando SJ, Sanelli P, Karimi S, Raiteri V, Barnhill JW (2005)
The clock drawing test: diagnostic, functional, and neuroimaging
correlates in older medically ill adults. J Neuropsychiatry Clin Neurosci
17:533–540
CrossRef (https://doi.org/10.1176/jnp.17.4.533)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16387994)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=The%20clock%20drawing%20test%3A%20diagnostic%2C%20functi
onal%2C%20and%20neuroimaging%20correlates%20in%20older%20me
dically%20ill%20adults&author=JB.%20Samton&author=SJ.%20Ferrand
o&author=P.%20Sanelli&author=S.%20Karimi&author=V.%20Raiteri&au
thor=JW.%20Barnhill&journal=J%20Neuropsychiatry%20Clin%20Neuro
sci&volume=17&pages=533-540&publication_year=2005)
36. Caffarra P, Gardini S, Zonato F, Concari L, Dieci F, Copelli S, Freedman M,
Stracciari A, Venneri A (2011) Italian norms for the Freedman version of
the Clock Drawing Test. J Clin Exp Neuropsychol 33:982–988
CrossRef (https://doi.org/10.1080/13803395.2011.589373)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22082081)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Italian%20norms%20for%20the%20Freedman%20version%20of%2
0the%20Clock%20Drawing%20Test&author=P.%20Caffarra&author=S.%
20Gardini&author=F.%20Zonato&author=L.%20Concari&author=F.%20
Dieci&author=S.%20Copelli&author=M.%20Freedman&author=A.%20Str
acciari&author=A.%20Venneri&journal=J%20Clin%20Exp%20Neuropsyc
hol&volume=33&pages=982-988&publication_year=2011)
37. Babins L, Slater ME, Whitehead V, Chertkow H (2008) Can an 18-point
clock-drawing scoring system predict dementia in elderly individuals with
mild cognitive impairment? J Clin Exp Neuropsychol 30:173–186
CrossRef (https://doi.org/10.1080/13803390701336411)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18938669)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Can%20an%2018-point%20clock-
drawing%20scoring%20system%20predict%20dementia%20in%20elderly
%20individuals%20with%20mild%20cognitive%20impairment%3F&auth
or=L.%20Babins&author=ME.%20Slater&author=V.%20Whitehead&auth
or=H.%20Chertkow&journal=J%20Clin%20Exp%20Neuropsychol&volum
e=30&pages=173-186&publication_year=2008)
38. Caffarra P, Gardini S, Zonato F, Concari L, Dieci F, Copelli S, Freedman M,
Stracciari A, Venneri A (2011) Italian norms for the Freedman version of
the Clock Drawing Test. J Clin Exp Neuropsychol 33:982–988
CrossRef (https://doi.org/10.1080/13803395.2011.589373)
PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22082081)
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Italian%20norms%20for%20the%20Freedman%20version%20of%2
0the%20Clock%20Drawing%20Test&author=P.%20Caffarra&author=S.%
20Gardini&author=F.%20Zonato&author=L.%20Concari&author=F.%20
Dieci&author=S.%20Copelli&author=M.%20Freedman&author=A.%20Str
acciari&author=A.%20Venneri&journal=J%20Clin%20Exp%20Neuropsyc
hol&volume=33&pages=982-988&publication_year=2011)
39. Freedman A, Leach A, Kaplan E, Winocur G, Shulman KJ, Delis DC (1994)
Clock drawing. Oxford University Press, A neuropsychological analysis.
New York
Google Scholar (http://scholar.google.com/scholar_lookup?
title=Clock%20drawing&author=A.%20Freedman&author=A.%20Leach&
author=E.%20Kaplan&author=G.%20Winocur&author=KJ.%20Shulman
&author=DC.%20Delis&publication_year=1994)
Copyright information
© Springer-Verlag Italia 2016

About this article


Cite this article as:
Ricci, M., Pigliautile, M., D’Ambrosio, V. et al. Neurol Sci (2016) 37: 867.
https://doi.org/10.1007/s10072-016-2480-6

Received 17 September 2015


Accepted 09 January 2016
First Online 10 February 2016
DOI https://doi.org/10.1007/s10072-016-2480-6
Publisher Name Springer Milan
Print ISSN 1590-1874
Online ISSN 1590-3478

About this journal


Reprints and Permissions

Published in cooperation with

the Italian Neurological Society

Personalised recommendations

1. The clock-drawing test: normative data in adult and elderly Israeli Arabs
Merims, Doron… Boguslavsky, Tania
Psychogeriatrics (2018)

2. Normative data for the Clock Drawing Test for French-Quebec mid- and
older aged healthy adults
Turcotte, Valérie… Hudon, Carol
The Clinical Neuropsychologist (2018)

3. Predictors of cognitive impairment assessed by Mini Mental State


Examination in community-dwelling older adults: relevance of the step
test
Muscari, Antonio… Zoli, Marco
Experimental Gerontology (2018)

Want recommendations via email? Sign up now Powered by:


© 2018 Springer Nature Switzerland AG. Part of Springer Nature.

Not logged in Not affiliated 118.136.114.134

Вам также может понравиться