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A tzank smear is used to confirm a viral infection by identifying multinucleated giant cells from a vesicle. To perform the test, the debris from a freshly ruptured vesicle is gently scraped onto a microscope slide. The slide is heated, stained using Giemsa, Pap, or Wright's stain, rinsed, and a cover slip applied. Under the microscope at 10x and 43x power, multinucleated giant cells indicate a positive result for infection by herpes simplex virus or varicella zoster virus.
A tzank smear is used to confirm a viral infection by identifying multinucleated giant cells from a vesicle. To perform the test, the debris from a freshly ruptured vesicle is gently scraped onto a microscope slide. The slide is heated, stained using Giemsa, Pap, or Wright's stain, rinsed, and a cover slip applied. Under the microscope at 10x and 43x power, multinucleated giant cells indicate a positive result for infection by herpes simplex virus or varicella zoster virus.
A tzank smear is used to confirm a viral infection by identifying multinucleated giant cells from a vesicle. To perform the test, the debris from a freshly ruptured vesicle is gently scraped onto a microscope slide. The slide is heated, stained using Giemsa, Pap, or Wright's stain, rinsed, and a cover slip applied. Under the microscope at 10x and 43x power, multinucleated giant cells indicate a positive result for infection by herpes simplex virus or varicella zoster virus.
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