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Of all the lousy things that can happen, this has to be one of the worst.
Imagine: You’ve just completed the most successful bulking cycle (http://www.romanfitnesssystems.com/blog/from-novembeard-to-
decembulk-muscle-gaining-information-qa-and-my-dog/) of your life, adding twenty pounds of mass; you’re on top of the world. Now, all
you have to do is train properly and eat plentifully (http://www.romanfitnesssystems.com/blog/basic-muscle-building-hardgainers/) in
order to solidify your gains.
Your girlfriend is so proud of you for making such great gains and transforming your physique that she can’t keep her hands off you.
The day before, she had taken a sip from the water fountain at the gym and accidentally touched her lips to the spout. Ten minutes
earlier, that skanky “human sweat gland” guy who spends five hours on the elliptical each day had just made out with that same water
fountain. That morning, he had kissed his wife goodbye before leaving for the gym. She teaches a kindergarten class that, incidentally,
happens to be riddled with the flu…
So here you are. Home sick from work, pitying yourself as you watch the same episode of Sportscenter eight times in a row. All the
while, you’re thinking about how you would much rather be deadlifting (www.romanfitnesssystems.com/blog/how-i-fixed-lower-back-
pain/) like a madman and showing off your gains at the gym!
But you need to focus on the task at hand: beating the flu*. Whether you’re a bodybuilder
(http://www.romanfitnesssystems.com/blog/bodybuilding/), powerlifter, or a different athlete
(http://www.romanfitnesssystems.com/blog/guest-post-a-multifaceted-approach-for-a-multipurpose-body/), you need to take into
account how sickness affects performance and physical appearance, whereas normal folks just worry about “getting rid of their sniffles.”
They might make you feel all warm and toasty on the inside, but they’ll quickly make you soft and fluffy on the outside.
This decrease should account for the extra time spent on the couch or in bed.
(https://i0.wp.com/romanfitnesssystems.com/wp-
content/uploads/2011/02/2186673560_48880bccc8_z.jpg)
Photo: Mike
(https://www.flickr.com/photos/anotherpintplease/)
You’ll want 1-1.5g/lb lean body mass in order to remain in positive nitrogen balance and stop muscle breakdown in its tracks.
Don’t fall into the trap of overdoing the Omega-3s. While fish oil has proven effective in enhancing immune function in certain clinical
situations (e.g. rheumatoid arthritis, ulcerative colitis) and in animals, studies of healthy humans are yet to yield consistently favorable
results to substantiate the claim that Omega-3s enhance immunity (4). As such, there does not appear to be any greater benefit (at least
not yet) to increasing Omega-3 PUFA intake during times of sickness. Simply stick to your normal intake levels, relying on healthy
sources such as fish oil and flaxseed (http://www.romanfitnesssystems.com/blog/salad-dressing/) oil for your supplemental fat intake.
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(https://i0.wp.com/romanfitnesssystems.com/wp-content/uploads/2011/02/waterfall-335985_1920.jpg)You might think that because you
aren’t training, you don’t need to worry much about H2O- big mistake. The body loses a significant amount of fluids each day
independent of training. We’re constantly losing water through our breath as we dissipate heat through our skin without even knowing
it. Factor in increased mucus production, the sweating that may be associated with a fever, the fact that your body is constantly
constructing new cells (especially during sickness), not to mention your higher protein intake, and you can begin to realize the
importance of really emphasizing water intake. Shoot for at least one gallon (preferably more) of water daily.
All these considerations in mind, I highly recommend you pick up a copy of Precision Nutrition
(http://www.precisionnutrition.com/cmd.php?af=364769) from Dr. John Berardi. His information is fantastic, highly effective, and
presented in a user-friendly format.
From a weight-training standpoint, fewer sick days corresponds to fewer missed training sessions. In addition to the flu shot and your
regular multivitamin, you should definitely include the following:
2. VITAMIN C
During infection, in order to prevent oxidative damage, the vitamin C within the leukocytes is used up faster than a post-workout shake
(http://www.romanfitnesssystems.com/blog/what-to-eat-when-to-eat-it-a-brief-discussion-of-paraworkout-nutrition/) (4)! Thus, it should
come as no surprise that reduced leukocyte vitamin C levels are associated with less than optimal immune function. (6)
Despite some controversy(7), it appears that supplementation with vitamin C improves several aspects of the human immune
response (8, 9), affecting positive changes in proliferation and/or function of in three of the five types of leukocytes: lymphocytes,
neutrophils, and monocytes (10-16).
Based on the available literature, I recommend 2-2.5g of supplemental vitamin C daily during normal training conditions and 4-5g
daily during flu-like symptoms and times increased of training stress. Doses of up to 10g per day have been used in numerous studies
without serious toxicity symptoms, though the side effects of such high consumption may include diarrhea and, in serious cases, kidney
stones or urate crystals” (7). Be sure to spread your intake throughout the day in 500mg doses to maximize the absorption(17).
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3. VITAMIN E
Even the slightest deficiency in vitamin E can easily compromise one’s immune response. The current RDA of 30 IU is barely adequate
in preventing deficiency in sedentary individuals, let alone in athletes, the elderly, and the sick and diseased. You might be able to
consume a lot of vitamin E from diet alone (3 ounces of almonds or 2 ounces of sunflower seeds should meet the RDA), but in order to
receive enough vitamin E to help ward off the flu, you’ll need a lot more. Don’t worry, vitamin E is one of the least toxic vitamins,
although one may experience some minor symptoms (nausea, diarrhea, muscle weakness) with very high dosages (7,21). As such, 800-
1200 IU per day, throughout the year (regardless of whether you’re sick or healthy) is an optimal approach.
4. GLUTAMINE
Because glutamine is crucial for a variety of metabolic processes, it is only logical that a sick body requires more of it in order to “bolster” the immune
system while maintaining normal physiological functioning (24,26).
The body’s response to infection, injury, and stress is muscle breakdown. In order to sustain its metabolic processes, the body takes
glutamine from muscle. Normally, this isn’t a big deal because the body makes its own glutamine, but during times of stress or sickness,
numerous organs show marked increases in glutamine uptake. When combined with the needs of the immune system, GI tract, and the
regular metabolic processes, glutamine gets sapped faster than you can make it, and your beloved quads become fuel for your body’s
lunch(23,27).
Obviously, you need to supplement with glutamine. Numerous studies have shown that doing so helps to maintain positive nitrogen
balance, improve muscle protein synthesis rates, increase growth hormone (http://www.romanfitnesssystems.com/blog/intermittent-
fasting-faq/), and enhance immune function(7, 28-35). Also, let’s not forget that glutamine’s ability to enhanve your immune system
makes it an effective year-round, recovery-promoting supplement for hard training athletes, especially during and shortly after periods
of intensive training (7,33,34). During illness, shoot for 0.35-0.4 grams of glutamine per kilogram of body weight, and spread your intake
out throughout the day in 3-5g doses. Based on absorbability, I recommend glutamine peptides. L-glutamine (free form), however, tastes
better, generally costs less, and will also yield favorable results.
5. ZINC
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Studies on the benefits of zinc supplementation in enhancing immune function have yielded mixed, but mostly favorable results.
Popping zinc pills upon the onset of a cold or upper respiratory tract infection has been shown in some studies to decrease the
sickness’ duration and severity (7,37-39). Meanwhile, zinc supplementation in long distance runners prevented the typical increase in
reactive oxidation normally seen with endurance activity (41).
If you take nothing else from all these studies, at least walk away from this article cognizant of how important sufficient intake is,
especially for athletes—who are more likely to be deficient than the general population. In terms of preventative supplementation,
researchers found that of 609 school children, those who supplemented with zinc had 45% fewer acute lower respiratory infections
over the 120-day study (42). While too much supplementation can suppress the immune system, moderate supplementation throughout
the year with slightly increased dosages beginning at the onset of flu- or cold-like symptoms is an effective and safe approach (7).
When you’re sick, take at least 25 milligrams of zinc per day, and no more than 100 grams. I like the supplement ZMA, as it will enable
you to meet your zinc needs while increasing anabolic hormone levels, improving recovery, and promoting deep, restful sleep.
ECHINACEA
Although a few studies show slightly (and relatively insignificantly) shorter respiratory tract infections in patients treated with echinacea,
most have demonstrated that the herbal product has little or no effect on preventing and treating sickness. The surrounding science is
made murkier by the fact that there are nine species of the plant, different parts (leaves, stem, roots, flowers) of the plant can be used,
and different forms are available (e.g. powder, liquid extract, capsule). Essentially, even if echinacea was definitively proven effective, an
argument would still exist over which species, form, and delivery produces the best results. At this point, there is not enough evidence
to recommend echinacea as a worthy supplement (7,43-45).
ARGININE
There’s some evidence that this nonessential amino acid can improve immune response and wound healing by boosting lymphocyte
production in people with compromised health status. However, most studies have shown that arginine supplementation is of no benefit
if you’re trying to enhance the immune response, especially in healthy individuals (7). Given that some clinical trials use upwards of 20g
L-arginine per day (mostly without appreciable immunity-related results), forty capsules per day seems like far too risky an investment
even if you enjoy being a human guinea pig. Even if you do decide to give arginine a try, be careful; excessive intakes can actually blunt
the immune response (46).
AND FINALLY…
(https://i2.wp.com/romanfitnesssystems.com/wp-content/uploads/2011/02/sleeping-56468_640.jpg)
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The old “8-hours at night” recommendation still holds true… as a minimum. You should also be shooting for a nap or two during the
day.
It seems like a no-brainer to say that you shouldn’t be training when you’re sick, but I’m constantly amazed at how many people still go
the gym in spite of their wheezing, sore throats, and aches. Before you stumble off the couch and over to your local gym, ask yourself if
your body could really recover from a heavy training session if it hasn’t even recovered from the flu.
If that doesn’t send you home, maybe it will help to think about how your decision to go train will impact others; you’ll probably make
half the people in the gym sick just like the “human sweat gland” did to you. Stay home, if not for your own sake, then for the sake of
everyone else who enjoys his or her health and visits to the gym.
References
1. The Merck Manual of Diagnosis and Therapy. http://www.merck.com/pubs/mmanual/section13/chapter162/162b.htm; 1995 accessed
Sept 2002.
2. Coss-Bu JA et al. Energy metabolism, nitrogen balance, and substrate utilization in critically ill children. Am J Clin Nutr 2001
Nov;74(5):664-9.
3. Calder PC et al. Fatty acids and lymphocyte functions. Br J Nutr 2002 Jan;87 Suppl 1:S31-48.
4. Field C. et al. Nutrients and their role in host resistance to infection. J Leukoc Biol 2002 Jan;71(1):16-32.
5. Mixeu MA et al. Impact of influenza vaccination on civilian aircrew illness and absenteeism. Aviat Space Environ Med 2002
Sep;73(9):876-80
6. Schwager, J. et al. Modulation of interleukin production by ascorbic acid. Vet Immunol Immunopathol. 1998 Jun 30;64(1):45-57.
7. Antonio, J., & Stout, J. Sports Supplements. Lippincott Williams & Wilkins, 2001.
8. Hemila, H. Vitamin C and common cold incidence: a review of studies with subjects under heavy physical stress. Int J Sports Med
1996 Jul;17(5):379-83.
9. Hemila, H. Vitamin C and acute respiratory infections. Int J Tuberc Lung Dis 1999 Sep;3(9):756-61.
10. Kennes, B. et al. Effect of vitamin C supplements on cell-mediated immunity in old people. Gerontology 1983;29(5):305-10.
11. Penn, ND. et al. The effect of dietary supplementation with vitamins A, C and E on cell-mediated immune function in elderly long-stay
patients: a randomized controlled trial. Age Ageing 1991 May;20(3):169-74.
12. Shilotri PG, & Bhat KS. Effect of mega doses of vitamin C on bactericidal ativity [sic] of leukocytes. Am J Clin Nutr 1977 Jul;30(7):1077-
81
13. de la Fuente, M. et al. Immune function in aged women is improved by ingestion of vitamins C and E. Can J Physiol Pharmacol 1998
Apr;76(4):373-80.
14. Patrone, F. et al. Effects of ascorbic acid on neutrophil function. Studies on normal and chronic granulomatous disease neutrophils.
Acta Vitaminol Enzymol 1982;4(1-2):163-8.
15. Prinz, W. The effect of ascorbic acid supplementation on some parameters of the human immunological defense system. Int J Vit
Nutr Res 1977; 47:248-57.
16. Woollard, KJ. et al. Effects of oral vitamin C on monocyte: endothelial cell adhesion in healthy subjects. Biochem Biophys Res
Commun 2002 Jun 28;294(5):1161-8.
17. Voldani, A. et al. New evidence for antioxidant properties of vitamin C. Cancer Detect Prev. 2000;24(6):508-23.
18. Meydani, SN et al. Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects. Am J Clin Nutr. 1990
Sep;52(3):557-63.
19. Meydani, SN et al. Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial.
JAMA. 1997 May 7; 277(17):1380-6.
20. Han, SN et al. Effect of long-term dietary antioxidant supplementation on influenza virus infection. J Gerontol A Biol Sci Med Sci
2000 Oct;55(10):B496-503.
21. Beharka A. et al. Vitamin E status and immune function. Methods Enzymol 1997;282:247-63
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22. Yeh, SL et al. Effects of glutamine-supplemented total parenteral nutrition on cytokine production and T cell population in septic rats.
JPEN J Parenter Enteral Nutr. 2001 Sep-Oct;25(5):269-74.
23. van Acker, BA et al. Glutamine: the pivot of our nitrogen economy? JPEN J Parenter Enteral Nutr. 1999 Sep-Oct;23(5 Suppl):S45-8.
Review.
24. Newsholme, P. Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection? J
Nutr. 2001 Sep;131(9 Suppl):2515S-22S; discussion 2523S-4S. Review.
25. Saito, H. et al. Glutamine as an immunoenhancing nutrient. JPEN J Parenter Enteral Nutr. 1999 Sep-Oct;23(5 Suppl):S59-61. Review.
26. Ziegler, TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy.
J Nutr. 2001 Sep;131(9 Suppl):2578S-84S; discussion 2590S. Review.
27. Karinch AM. et al. Glutamine metabolism in sepsis and infection. J Nutr 2001 Sep;131(9 Suppl):2535S-8S; discussion 2550S-1S.
28. Wilmore, DW. The effect of glutamine supplementation in patients following elective surgery and accidental injury. J Nutr. 2001
Sep;131(9 Suppl):2543S-9S; discussion 2550S-1S. Review.
29. Boelens PG. et al. Glutamine alimentation in catabolic state. J Nutr. 2001 Sep;131(9 Suppl):2569S-77S; discussion 2590S. Review.
30. Yoshida, S. et al. Effects of glutamine supplements and radiochemotherapy on systemic immune and gut barrier function in patients
with advanced esophageal cancer. Ann Surg. 1998 Apr;227(4):485-91.
31. Valencia, E. et al. Impact of oral L-glutamine on glutathione, glutamine, and glutamate blood levels in volunteers. Nutrition. 2002
May;18(5):367-70.
32. Yoshida, S. et al. Glutamine supplementation in cancer patients. Nutrition. 2001 Sep;17(9):766-8.
33. Castell LM., & Newsholme EA. The effects of oral glutamine supplementation on athletes after prolonged, exhaustive exercise.
Nutrition 1997 Jul-Aug;13(7-8): 738-42.
34. Rosene, MF. et al. Glutamine supplementation may maintain nitrogen balance in wrestlers during a weight reduction program. Med
Sci Sports Exerc 1999;31(5): S123.
35. Welbourne, TC. Increased plasma bicarbonate and growth hormone after an oral glutamine load. Am J Clin Nutr. 1995
May;61(5):1058-61.
36. Fraker, PJ. et al. The dynamic link between the integrity of the immune system and zinc status. J Nutr 2000 May;130(5S
Suppl):1399S-406S.
37. Prasad AS. et al. Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A
randomized, double-blind, placebo-controlled trial. Ann Intern Med 2000 Aug 15;133(4):245-52.
38. Al-Nakib, W. et al. Prophylaxis and treatment of rhinovirus colds with zinc gluconate lozenges. J Antimicrob Chemother. 1987
Dec;20(6):893-901.
39. Mossad, SB. et al. Zinc gluconate lozenges for treating the common cold. A randomized, double-blind, placebo-controlled study.
Ann Intern Med. 1996 Jul 15;125(2):81-8.
40. Berger MM. et al. Trace element supplementation modulates pulmonary infection rates after major burns: a double-blind, placebo-
controlled trial. Am J Clin Nutr. 1998 Aug;68(2):365-71.
41. Singh A. et al. Exercise-induced changes in immune function: effects of zinc supplementation. J Appl Physiol 1994 Jun;76(6):2298-
303.
42. Sazawal S. et al. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children:
a double-blind, controlled trial. Pediatrics. 1998 Jul;102(1 Pt 1):1-5.
43. Gunning, K. Echinacea in the treatment and prevention of upper respiratory tract infections. West J Med. 1999 Sep;171(3):198-200.
44. Brinkeborn RM. et al. Echinaforce and other Echinacea fresh plant preparations in the treatment of the common cold. A randomized,
placebo controlled, double-blind clinical trial. Phytomedicine. 1999 Mar;6(1):1-6.
45. Grimm, W, & Muller, HH. A randomized controlled trial of the effect of fluid extract of Echinacea purpurea on the incidence and
severity of colds and respiratory infections. Am J Med. 1999 Feb;106(2):138-43.
46. Wiebke EA. et al. Effects of L-arginine supplementation on human lymphocyte proliferation in response to nonspecific and
alloantigenic stimulation. J Surg Res 1997 Jun;70(1):89-94.
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* Disclaimer: The term “flu,” short for influenza, is really only one of several common kinds of viral respiratory infections, like the common
cold, pharyngitis, laryngitis, tracheobronchitis, and viral pneumonia (1). Regardless of the clear differences in the nuts and bolts of each
infection, they are generally all lumped together and called the flu by the general public. It’s erroneous, but that said, these tips will
apply to the majority of “flus” out there.
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Name
Gotta give credit to Eric for all that time he spent refering to all those studies. :P
Though I'm never sick these days, I remember when my whole family was sick and I had nothing, except for one headache I had in the morning or
so.
Anyway, I am thinking about the english translation of the dutch 'Beterschap' but it comes down to wishing you to get well soon.
△ ▽ • Reply • Share ›
Gotta give credit to Eric for all that time he spent refering to all those studies. :P
Though I'm never sick these days, I remember when my whole family was sick and I had nothing, except for one headache I had in the morning or
so.
Anyway, I am thinking about the english translation of the dutch 'Beterschap' but it comes down to wishing you to get well soon.
△ ▽ • Reply • Share ›
You guys constantly put out quality stuff. You don't disappoint.
I admit that I hate to sit and rest and not train. It feels like I'm being lazy, but I know I must take it easy when I'm sick to be stronger in the long run.
You guys constantly put out quality stuff. You don't disappoint.
I admit that I hate to sit and rest and not train. It feels like I'm being lazy, but I know I must take it easy when I'm sick to be stronger in the long run.
I hope you get well soon, Roman. Just so you know, I get sick just once a year!
I feel that plenty of rest, not worrying too much about your caloric intake, staying away from fried or heaty foods and focusing on the healthy,
nutritious ones and waiting at least a day after recovering are all that's needed. Oh, and take your meds on time.
As for muscle loss, I believe that any "loss" would be due to water and glycogen. It's impossible to lose the actual contractile tissue/muscle protein,
unless you're starved of food or activity for about a month! Once you start training again, your muscles will balloon (literally) back up to their
previous size. Catabolism is overrated.
That aside, I really like your vitamin prescriptions. People get sick because of the hit they've taken to their immune system, and proper
supplementation is usually what's needed.
I find that at times, I don't even need to take any medicine - multivitamins are effective on their own!
△ ▽ • Reply • Share ›
I hope you get well soon, Roman. Just so you know, I get sick just once a year!
I feel that plenty of rest, not worrying too much about your caloric intake, staying away from fried or heaty foods and focusing on the healthy,
nutritious ones and waiting at least a day after recovering are all that's needed. Oh, and take your meds on time.
As for muscle loss, I believe that any "loss" would be due to water and glycogen. It's impossible to lose the actual contractile tissue/muscle protein,
unless you're starved of food or activity for about a month! Once you start training again, your muscles will balloon (literally) back up to their
previous size. Catabolism is overrated.
That aside, I really like your vitamin prescriptions. People get sick because of the hit they've taken to their immune system, and proper
supplementation is usually what's needed.
I find that at times, I don't even need to take any medicine - multivitamins are effective on their own!
△ ▽ • Reply • Share ›
W • 7 years ago
Lots of solid information there, but I can't believe you didn't mention vitamin D. It plays a very important role in immunity, and since most of us don't
spend enough time out of doors we don't manufacture enough of it.
△ ▽ • Reply • Share ›
W • 7 years ago
Lots of solid information there, but I can't believe you didn't mention vitamin D. It plays a very important role in immunity, and since most of us don't
spend enough time out of doors we don't manufacture enough of it.
△ ▽ • Reply • Share ›
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py
Anyway, now that I have kissed some ass, I get to tell you how sick I was this year: It was cold that night. Bitterly cold. The kind of cold that makes
you want your mama, or at least put your shirt back on even though you just did a huge chest routine. That was when I first felt the tickle...
Blah, blah, blah. Suffice it to say, I got sick before I read this article, and even though it is no excuse, did all of the wrong things. Flash forward 2
weeks, and I am down 7 pounds and my betta is acting all hard at me because he thinks he can take me down.
△ ▽ • Reply • Share ›
Anyway, now that I have kissed some ass, I get to tell you how sick I was this year: It was cold that night. Bitterly cold. The kind of cold that makes
you want your mama, or at least put your shirt back on even though you just did a huge chest routine. That was when I first felt the tickle...
Blah, blah, blah. Suffice it to say, I got sick before I read this article, and even though it is no excuse, did all of the wrong things. Flash forward 2
weeks, and I am down 7 pounds and my betta is acting all hard at me because he thinks he can take me down.
△ ▽ • Reply • Share ›
Ni
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Nina • 6 years ago
Another reason to not go to the gym: limit the spread of your own flu! (Unlike Mr. Sweat Gland elliptical-addict)
△ ▽ • Reply • Share ›
http://health.usnews.com/he...
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http://health.usnews.com/he...
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Feel better.
:)
△ ▽ • Reply • Share ›
Feel better.
:)
△ ▽ • Reply • Share ›
You make me feel desperate sometimes, 'cause I study a looooot and every day I see there soooooooo much more to learn...
Antonio.
△ ▽ • Reply • Share ›
You make me feel desperate sometimes, 'cause I study a looooot and every day I see there soooooooo much more to learn...
Antonio.
△ ▽ • Reply • Share ›
I will have a surgery next week (hernia repair surgery), what do you think in adopting some of your usefull tips to my post operatory recovery???, of
course i will consult my Dr. 1st...
BR,
Mr. B
△ ▽ • Reply • Share ›
I will have a surgery next week (hernia repair surgery), what do you think in adopting some of your usefull tips to my post operatory recovery???, of
course i will consult my Dr. 1st...
BR
http://romanfitnesssystems.com/articles/staying-fit-when-sick/ 11/19
28/1/2018 The Complete Guide to Maintaining Muscle When You're Sick
BR,
Mr. B
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ah • 5 years ago
Except that the flu shot only makes things worse...probably the reason that many countries in Europe have banned it...
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