Drug Antidote

acetylcysteine
Acetaminophen/Tylenol/Paracetamol
(Mucomyst)

Anticholinergics, diphenhydramine,
Physostigmine
dimenhydrinate

atrophine sulfate
Anticholinesterase
or pralidoxime

Fomepizole,
Antifreeze
Ethanol

D-Penicillamine
Arsenic, Copper, Lead, Mercury
(Cuprimine )

Benzodiazepines flumazenil

Beta-Blocking agents, Calcium channel

Glucagon,
blockers, Hypoglycemia, Hypoglycemic
Epinephrine
agents

Calcium Chloride,
Calcium Channel Blockers
Glucagon

Phytonadione or
Coumadin/Warfarin
Vitamin K

Amyl nitrite,
Cyanide sodium nitrite,
sodium thiosulfate

Cyclophosphamide Mesna

Digibind or Digoxin
Digoxin
Immune Fab

phentolamie
Dopamine
(Regitine)

Ethylene glycol fomepizole

ethyllene poisoning antizol

diphenhydramine
Extrapyramidal symptoms (EPS)
(Benadryl)
Fluorouracil leucoverin calcium

Heparin protamine sulfate

Naloxone (Narcan)
Heroin
or Nalmefene

glucose (Dextrose
Insulin reaction
50%)

Iron Deferoxamine

Pyridoxine HCl
Isoniazid, ethylene glycol
(Vitamin B6)

dimercapol,
Lead edetate calcium,
disodium,

Local anesthetics and possibly other

Fat emulsion
cardiac toxins (e.g., bupropion, calcium
(Intralipid , Liposyn
channel blockers, cocaine, beta blockers,
II , Liposyn III )
tricyclic antidepressants)

lovenox protamine sulfate

magnesium sulfate calcium gluconate

magnesium sulfate calcium gluconate

Methanol Folic acid

Methotrexate Leucovorin calcium

Narcotics, morphine sulfate naloxone (Narcan)

anticholinesterase
Neuromuscular blockade (paralytics)
agents

nalmefene or
Opioid analgesics
naloxone

albuterol inhaler,
insulin & glucose,
Potassium
NaHCO3,
kayexalate
Sodium channel blockers (e.g. cyclic Sodium
antidepressants), salicylates Bicarbonate

Octreotide
Sulfonylureas
(Sandostatin )

phyostigmine or
Tricyclic antidepressants
NaHCO3

Valproic acid L-Carnitine