Paras Biopharmaceuticals Finland Oy Announces Successful Development of

Biologically Active Romiplostim (N-Plate® Biosimilar) Production Technology

Oulu, Finland, January 31, 2019 --(PR.com)-- Paras Biopharmaceuticals Finland Oy today announced
the achievement of a major milestone - the successful development of biologically active Romiplostim
(N-Plate® biosimilar) production technology.

Romiplostim has been produced with a proprietary and innovative continuous manufacturing process at
the company's Finnish-based facility in Oulu-Finland. Romiplostim is used for the treatment of
thrombocytopenia (low platelet count) in patients with chronic immune (idiopathic) thrombocytopenic
purpura (ITP).

ITP is a potentially serious blood disorder characterized by increased destruction and impaired production
of platelets. It can lead to extensive bruising and bleeding. Thrombocytopenia is common in cancer
patients, resulting from chemotherapy or radiation treatment, in addition to the underlying disease itself.
ITP leads to several complications. Low platelet count increases spontaneous bleeding, complicates
surgical operations and can affect chemotherapy and radiation therapy.

By manufacturing its first batches of the Romiplostim biosimilar, Paras Biopharmaceuticals is in a

position to prepare to initiate GMP batches of the drug substance and formulation in 2019 within its
Romiplostim biosimilar development program. “The development and implementation of this
commercial-scale manufacturing process for Romiplostim is not only good news for the company but the
wider healthcare environment,” said Dr Ashesh Kumar, CEO & Director: Biologics & Licensing.

“The company is evaluating completed batches to assess comparability and looks forward to finalizing
this work in the anticipation of supporting clinical trials & approvals for commercial supply on patent
expiry in Europe and USA,” says Dr Mark Jackson Research & Admin Group, Paras Biopharmaceuticals.

Global occurrence of ITP is increasing, and a growing number of patients diagnosed/reported to be

affected. Current costs of available medicines are very expensive primarily due to higher production costs
and inefficient production processes. Current yearly treatment in USA can cost up to $55250 USD per
year for each ITP patient. With Paras Biopharmaceuticals efficient production technologies, the company
aims to provide affordable healthcare treatment options to patients suffering from ITP.

About Paras Biopharmaceuticals Finland Oy

Paras Biopharmaceuticals Finland Oy is a Finnish biopharmaceuticals company started in 2012.
Comprising of protein scientists, bioprocess engineers and technologists, Paras Biopharmaceuticals' team
has strong experience in developing biologics in the most efficient manner.

Company's main activities & offerings are in 3 major areas:

1. Contract development & microbial biologics manufacturing (CDMO).
2. Development & Licensing of Biosimilars.
3. Recombinant Bioprocess Enzymes - TEV protease and Recombinant Enterokinase.

Page 1/3
PR.com Press Release Distribution Terms of Use
Paras Biopharmaceuticals has a fully equipped microbial production facility in Finland for the production
of recombinant therapeutic products. With a total floor area of 25,000 ft2 and a classified cleanroom of
4,300 ft2, other features include media and buffer preparation, live area (fermentation and harvest &
extraction), purification suite (incl. +4°C cold room), final filtration and freeze-drying.

Paras Biopharmaceuticals has developed and is now offering clinical development and marketing
collaboration for the following Biosimilars: Recombinant Teriparatide (Forteo® Biosimilar),
Recombinant Anakinra (Kineret® Biosimilar), Analog Insulin Aspart®, Recombinant Rasburicase
(Elitek® / Fasturtec® Biosimilar) and Recombinant Romiplostim (N-plate® Biosimilar). The company
has achieved efficient and cost-effective production of high value biosimilars. Paras Biopharmaceuticals
has developed a proprietary platform which includes Diabrid® Technology, Noblecleav® Technology
and Biomultifold® Technology.

*Nplate® is a registered trademark of Amgen Inc.

For further details, visit the following website: www.parasbiopharma.com

For further information, please contact:

Paras Biopharmaceuticals Finland Oy
Media Relations & Information
Dr Mark Jackson Tel: +358 442709462 / Email: mark.jackson@parasbiopharma.com
Penny Härkönen Tel: +358442709462 / Email: penny.harkonen@parasbiopharma.com

Page 2/3
PR.com Press Release Distribution Terms of Use
Contact Information:
Paras Biopharmaceuticals Finland Oy
Dr. Mark Jackson
+358442905993
Contact via Email
www.parasbiopharma.com

Online Version of Press Release:

You can read the online version of this press release at: https://www.pr.com/press-release/775777

News Image:

Page 3/3
PR.com Press Release Distribution Terms of Use