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This R package, mrMLM, provides tools for multi-locus genome-wide association studies using random-SNP-effect mixed linear models. It conducts GWAS by first scanning each marker on the genome and applying a less stringent selection criterion to identify potentially associated markers. It then includes all potentially associated markers in a multi-locus model to estimate their effects using empirical Bayes and identify true quantitative trait nucleotides through likelihood ratio tests. The package contains functions for processing raw data, performing single-locus and multi-locus GWAS using different methods like FASTmrEMMA, FASTmrMLM, and ISIS EM-BLASSO.
This R package, mrMLM, provides tools for multi-locus genome-wide association studies using random-SNP-effect mixed linear models. It conducts GWAS by first scanning each marker on the genom…