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Taxonomy: The branch of biology that identifies, names, and classifies species (based on natural features)
-The ranks: Domain, Kingdom, Phylum, Class, Order, Family, Genus, and Species
Autotrophs vs Heterotrophs:
-Autotrophs : organism that captures energy from the sunlight or sometimes non-living substances to produce its
own energy-yielding food
-Heterotrophs: organism that cannot make its own food and gets its nutrients and energy from consuming other
organisms
Prokaryotic Eukaryotic
Genetic Material -circular DNA not bounded by -DNA in nucleus bounded
membrane membrane
Cell Division -not by mitosis and meiosis -by mitosis and meiosis
Reproduction -common asexual -common sexual
Number of Cells -unicellular -mostly multicellular
Organelles -mitochondria and other organelles -mitochondria and other membrane
are absent bound organelles present
Cellular Respiration -do not require oxygen to carry out -require oxygen to carry out
cellular respiration (anaerobic) cellular respiration (aerobic)
Viruses and Parasites: Viruses can live outside the human body but parasites need a host cell to love off of.
Bacteria and parasites can be killed with antibiotics but viruses cannot
Viruses a structure that contains strands of DNA or RNA surrounded by a protective protein coat (viruses
aren’t cellular so they need to invade a host cell to use its resources to replicate and function)
Capsid the outer protein layer that surrounds the genetic material of a virus
Example of Virus (Bacteriophage) Attacking Bacteriophage lands on host cells’ membrane, drills into the
membrane and releases its DNA which travels into the cell and goes into the Lytic or Lysogenic cycle
Lytic Cycle Viral DNA destroys cellular DNA, virus’s genetic material uses host cell to make new cells
(cells ribosomes breath in viral DNA so now the cell only makes viral protein and multiply and release more
viral cells
Lysogenic Cycle viral DNA enters the host cell and attaches onto the viral DNA, the cell does everything it
normally does but also makes viral DNA which goes into every cell it divides into. The problem is that these
cells could easily be triggered and all infected cells will react at once (then they’ll go into lytic cycle), its also
harder to detect (attachment, entry, attachment to cellular DNA)
How are viruses classified based on the size and shape of their capsid
Dichotomous Key: An identification tool consisting of a series of two-part choices that lead the user to a
correct identification
Unit 2: Evolution
Fossil Structures:
1)Homologous Structures: structures that have similar structural elements and origin but may have a different
function
2)Analogous Structures: structures that do not have a common evolutionary origin but perform similar functions
3)Vestigal Structures: structure that is reduced version of a structure that was functional in the organism’s
ancestors
Unit 3: Genetics
Cell Cycle-MITOSIS (for somatic cells-plant/animal cells that forms body of organism (besides reproductive
cells) *start:diploid somatic cell-end:two genetically identical diploid daughter cells
1)INTERPHASE:
G1 Growth
S DNA replicated (now there are 92 sister chromatids)
G2 Cell grows more
2)MITOSIS:
Prophase
1 Chromatid condenses into chromosomes
2 Centrioles move to opposite ends of the cell
3 Nucleur membrane begins to dissolve
4 Spindle fibres form
Metaphase
1 Spindle fibres connect to centrosomes on the centromeres
2 Spindle fibres line them up along the middle of the cell
Anaphase
1 Centromere divides
2 Spindle fibres retract, pulling the sister chromatids apart to
opposite sides of cell
Telephase
1 Nuclear membrane reappears
2 Chromosomes decondense into chromatids
3 Spindle fibres disappear
4 Formation of the cleavage furrow
3)CYTOKENESIS: (division of cell) splitting of cleavage furrow into
2 daughter cells
centromere region where the sister chromatids are held together in a chromosome homologous
centrioles/centrosome structure that helps to form the spindle fibres chromosomes
gene a section of DNA, a code alleles different variations of the genes chromosomes
genome complete DNA sequence of an organism (all the genetic material in our bodies) that contain the
chromatid DNA in loose form (condense into chromosomes by wrapping around histones) samechromosome
sequence
DNA in condensed form of genes as
another
Cell Cycle for germ cells: chromosome
MEIOSIS 1 *starts with a diploid germ cell (46 chromosomes) and ends with 4 raw haploid gamete cells (each
genetically different)
Interphase 1:G1, S, G2 DNA strands grow into chromosomes, that’s how they’re replicated
Prophase 1: each pair of homologous chromosomes (1 chromosome from each parent) bond through synapsis
and exchange genetic material through crossing over DNA, sister chromatids are no longer genetically identical
Metaphase 1: pairs of homologous chromosomes line up along equator of cell, spindle fibers attach to
centromere and independent assortment occurs (which is random alignment of chromosomes)
Anaphase 1: homologous chromosomes separate and move to opposite poles of cell and sister chromatids are
still together (centromere doesn’t split so two sister chromatids from each homologous pair moves to each pole
of cell
-chromosome number is reduced from 2n (diploid) to n (haploid)
Telophase1:homologous chromosomes begin to uncoil
-spindle fibres disappear
-cytokinesis happens forming nucleur membrane around each group of homologous chromosomes, two cells
form (technically they’re haploid b/c they have 46 chromatids but 23 chromosomes)
*No replication between Meiosis and Meiosis 2
MEIOSIS 2 (similar to mitosis)
Prophase 2: centrosomes duplicate, nuclear membrane disappears, spindle fibres form
Metaphase 2: haploid number of chromosomes lie up at the equator and spindle fibres attach to kinetocores on
centromeres
-2 chromosomes in each, 2 new haploid cells
Anaphase 2: sister chromatids pulled apart at centromers by spindle fibers (happening in both new haploid cells)
-now starts to form 4 new haploid cells (each haploid cell has 2 sister chromatids forming one chromosome)
Telephase 2: nuclear membrane forms around 4 new haploid cells each with half number of chromosomes from
the parent cell
synapsis the aligning of homologous chromosomes during prophase 1
What creates genetic diversity? Prophase 1-crossing over and Metaphase 1-independent
assortment
Oogenesis: the process of producing female gametes (eggs) in mammals and starts with ovam (female
gamete, plural ova)
Oogonia reproduce by mitosis after birth, begin meiosis 1 but stop at prophase 1, and at puberty meiosis
1 will continue to release one cell each month
Process:
-Start with diploid oogonium (oogonia) undergo mitosis before birth
-Remaining oogonia that don’t die undergo meiosis and become primary oocytes
-Primary oocytes pause during prophase 1 after replicating but before meiois 1 they stay rested until their
menstrual cycles begin
-When girl hit puberty p.o resume meiois from where they left off and finish meiois 1, (they stop at metaphase 2
unless they are fertilized) then divides chromosomes equally but there is unequal division of cytoplasm
-At cytokinesis almost all cytoplasm remains in one of the two daughter cells which becomes the secondary
oocyte
-The other daughter cell with half the chromosomes but little cytoplasm is called polar body and since its not
functional it’ll eventually degenerate and die
-S.o (has 2 copies of each chromosome) and become a fully functional ovum must undergo meosis 2 and
division in uneven again (where half chromosome going to small degenerate polar bear)
-The other half is gone to the ovum (half chromosome and almost all of cytoplasm) creating an egg
gamete male or female
reproductive cell zygote cell
formed by the fusion of two gametes
Spermatogenesis: the process of producing male gametes (sperm) in mammals-doesn’t start until puberty
Process:
-Starts with diploid cell called spermatogonium (plural spermatogonia)
-Spermatogonium germ cell undergoes mitosis to produce more spermatogonia (to keep sperm count high)
during puberty
-Cells grow gradually into primary spermatocytes preparing to divide into cells half their size
-Each primary spermatocytes undergo meiosis 1 to form two haploid calls known as secondary spermatocytes
-Secondary spermatocytes divide once more through meosis 2 and produce 4 haploid cells called spermatids
(containing half of the genetic material)
DNA Molecule
Centromere- region where the sister chromatids are held together in a chromosome
centrioles/centrosome- structure that helps to form the spindle fibres
gene- a section of DNA, a code alleles- different variations of the genes
genome- complete DNA sequence of an organism (all the genetic material in our bodies)
chromatid- DNA in loose form (condense into chromosomes by wrapping around histones)
chromosome- DNA in condensed form, made up of two sister chromatids
Scientific Contributions to Genetics:
-Aristotle proposed pangenesis egg and sperm consist of particles (pangenes) from all body parts (upon
fertilization pangenes develop into parts of the body from which they were formed)
-Antony van Leeuwenhoek discovered living sperm in semen and believed he saw complete miniature
person in the head of sperm
-Gregor Mendel developed theory of inheritance (through Pea plant study)
Epigenetics: when environmental factors control which genes are turned off and on
Digestive Diseases
Gallstones -hard deposits that form in the gallbladder because of too much cholesterol or waste in your bile that
does not allow the gallbladder to empty properly
-stones block ducts leading from gallbladder to intestines which causes sharp pain in the upper right abdomen
-can be dissolved with medications, but if that does not work, surgery is done to remove the stones
Diabetes- condition where body is unable to use glucose for energy
Type 1)insulin producing cells of pancreas are destroyed by the immune system and therefore no longer produce
insulin
Type 2)body doesn’t make enough insulin or is unable to properly use the insulin it makes, comes from high
sugar diets
Gestational)can develop during pregnancy because of hormones or inadequate levels of insulin production
Hepatitis- inflammation of the liver most commonly caused by a virus
A)caused by drinking contaminated water (there is a vaccine for it)
B)spread by sexual contact (vaccine to prevent it)
C)contracted by contact with infected blood (no vaccine for it)
Inflammatory Bowel Disease- the general name for a group of diseases that cause inflammation in the intestines
Ulcers-open sores that develop on the inside lining of your stomach and the upper portion of your small
intestine
Peptic ulcer-a sore in the lining of the stomach or duodenum, mostly caused by infection with the bacterium
Helicobacter pylori
-ulcers form when tissues become inflamed because protective mucus that covers the lining has weakened,
painful because unprotected tissue is in contact with acidic gastric juices
The Respiratory System:
Functions:
-gas exchange (breathing in oxygen and expelling carbon dioxide)
-make sound (forms our words by expelling air, changing position of our lips and tounge
2 ways to breathe in
Nasal cavity (nostrils which have villi to filter particles) and oral cavity
Pharynx-connects mouth and nasal cavity to larynx and esophagus
Larynx-structure between glottis and trachea that contains vocal cords
Trachea-carries air from nasal passages or mouth to bronchi, then lungs (also known as wind pipe)
Left and Right Bronchi- the passageway that branches from the trachea to the lungs
Bronchioles-branches from each bronchus inside the lung into increasingly smaller thin-walled tubes
Intercostal muscles-in between the ribs, these muscles plus the diaphragm contract when breathing and change
the volume of your therastic cavity
Alveoli (alveolus)- covered with capillaries, tiny sac found at the end of bronchioles, respiratory gases are
exchanged in this sac (expand and contract, oxygen we just brought in diffuses into the membrane)
External Respiration-oxygen is diffusing from the alveoli into the bloodstream and bonding with haemoglobin
Internal Respiration-happens at the tissue level where cells are
Respiratory Diseases
Asthma-caused by an irritance like pollen or dust, causes chronic inflammation of the lungs (redness and
soreness), its sometimes associated with mucus
Cystic Fibrosis- genetic, causes thick build up of mucus in lungs, resulting in infection, inflammation, and
damage to lung tissue (people that have it have shorter life spans)
Emphysema-chronic respiratory disease that affects the ability of the lungs to expel air, you don’t have as much
surface area for gas exchange, causes alveoli to burst ex. because of smoking
Laryngitis-inflammation of the larynx causes raspy voice (because the voice box is in larynx)
Pneumonia- causes inflammation in one or both lungs, usually caused by viral infection
Lobular-affects a single lobe
Bronchial- affects tubes (patches in both lungs in the area around brochi or bronchioles)
-alveoli fill up with thick fluid, making gas exchange difficult
Lung cancer-can be caused by inhaling smoke, in an x-ray it will show up as a white spot (chemotherapy can
be used to reduce size of cancer and then remove it)
Chest X-rays- common diagnostic, looks at bones and tumours (for pneumonia it will look cloudy around area)
MRI-looks at soft tissue
Cat Scan/CT Scan-gives a 360 degree view, shows cross sections, more details, less radiation
Summary:
4 Valves: 2 aortic valves 2 semi lunar-Tricuspid and Bicuspid valve
4 Chambers
2 Atria
2 Ventricles
4 Vessels: 2 Pulmonary (veins and arteries), exit artery (aorta), main entrance artery (vena cava)
Diseases
We have 2 arteries- one supplies heart (coronary arteries, if they’re blocked and not getting enough oxygen,
you’ll have a heart attack) one supplies brain
Aneurysm- bulge in an artery or heart chamber caused by a weakened area of the heart muscle or arterial wall
Congenital Heart Defects- any defect in the anatomical structure of the heart ex.hole in the septum
Hemophilia- when blood doesn’t clot properly
Stroke: Ishemic Stroke-blockage (clot) in the blood vessel, blocks flow of blood to the brain
Hemorrhagic Stroke-bursting of a blood vessel (in brain), so blood leaks into surrounding brain tissue
(the cerebral cavity)
Hypertension: high tension in arteries/ chronic high blood pressure (b/c of high salt diets)
Hypotension-low blood pressure
Hyperglycaemic-high blood sugar Hypoglycaemic-low blood sugar
Versatility of Cellulose:
-nutrients all energy comes from the sun and plants are the first living organisms that can take the energy,
so we get nutrients and energy from eating those plants
-plants harvest the sunlight’s energy and undergo cellular respiration to produce glucose (which is ATP
for themselves)
-gas exchange
-medicine all the different biochemicals we use for medicine comes from plants
-clothes cotton (comes from plants)
-building wood which comes from trees
-erosion control
-helps in flooding plants absorb rainfall so there is less chance of flooding in green space, help with water
cycle
Vascular plants-plants that have some sort of circulatory system, refer to anatomy diagram
Leaf Anatomy: Refer to diagram
Leaf Physiology:
-cuticle is a waxy layer on the epidermis that is secreted by epidermal cells
-epidermis is the dermal tissue that makes up a plant’s outer covering
-guard cells are specialized epidermal cells, in pairs they regulate (open and close) the opening of the stomata
-stoma (plural stomata) is a small opening that allows gas exchange to occur and water to pass through
Transpiration- the process of water evaporating from the inside of a leaf to the outside through the stomata
(water leaves the stoma)
Translocation- the transport of glucose throughout the plant, phloem is the structure that moves the sugar
Cohesion-tension Model- the process of the xylem moving water from the roots to the leafs (xylem is the
tubing structure the water moves through)
Tropism-a plant’s growth response to external stimulation coming from one direction in the environment
Phototropism-a plant’s growth response to light
Gravitropism- a plant’s growth response to gravity
Thigmotopism-a plant’s growth response to touch or contact
Nastic response- a plant’s movement in response to a stimulus that is not associated with the direction of
the stimulus (an unpredicted response)
Apical dominance- a condition of a plant stem where plants mainly grow upwards, with little growth from
side branches
Ecological succession- the change in an ecosystem that happens when one community replaces another,
resulting from changes in abiotic and biotic factors
Primary succession- establishment of a community in an area of exposed rock that does not have topsoil
(moss will grow on rock which will eventually turn into soil for plants)
Pioneer species-the first organisms to appear in primary succession
Secondary succession- changes that take place in a damaged ecosystem or in communities that have been
destroyed but the soil has remained intact
Pollination:
A Flower’s Reproductive Anatomy
-pistil the female reproductive part of the flower
-stamen the male reproductive part of the flower
-typically have cross-pollination one flower on one plant to another flower on another plant and self pollination
is when a flower fertilizes itself
-when a flower is open and blooming, it is ready to sexually reproduce
-when a bee (or any pollinator) has pollen stuck to it and it lands on a different flower, the pollen grain sticks to
the stigma, in the pollen grain there are two different types of cells, one is called the tube cell which is used to
burrow down a pollen tube from the stigma through the style to the inside area of the ovary then the generative
cell which is inclosed in the tube cell divides into two sperm cells, they target an ovule to fertilize (ovules egg
cell and two polar nuclei), one of them fertilizes an egg which forms a zygote, the second joins with the two
polar nuclei and develops into endosperm which is full of nutrients for the developing baby plant (double
fertilization). Then surrounding ovary develops into a fruit