B.Sc.

VI SEMESTER
DSE: - 2 ; CH- DSE- 161
ORGANOMETALICS, BIOINORGANIC, POLYNUCLEAR
HYDROCARBONS, SYNTHETIC POLYMERS, NATURAL PRODUCTS
(Credits: Theory-04, Theory: 60 Lectures, Time: 3 Hrs MM 70
Note:
a) Ten compulsory objective type questions of one mark each, 10 x 1 = 10 Marks
b) Examinees to solve four short answer questions out of eight (two from each unit).4 x 5 =20 Marks.
c) Examinees to solve four long answer questions out of eight (two from each unit).4 x 10 =40Marks
Section A: Inorganic Chemistry-4 (30 Lectures)
UNIT-1: Organometallic Compounds : (18 Lectures)
Definition and Classification with appropriate examples based on nature of metal-carbon bond (ionic,
s, p and multicentre bonds). Structures of methyl lithium, Zeiss salt and ferrocene. EAN rule as
applied to carbonyls. Preparation, structure, bonding and properties of mononuclear and polynuclear
carbonyls of 3d metals. p-acceptor behaviour of carbon monoxide. Synergic effects (VB approach),
MO diagram of CO can be referred to for synergic effect to IR frequencies.
Applications of Grignard reagents, organolithium, organoaluminium, organotin compounds in organic
synthesis. Their Industrial, agricultural and biological applications.
Preparation, properties, bonding and applications of Metal alkyls and aryls of Li, Al, Mg.
Metal ethylene complexes, the nature of bonding in metal carbonyls.
UNIT-2: Bio-inorganic Chemistry: ( 12 Periods)
Essential and trace elements in biological processes, Biological functions of Na, K, Mg, Ca, Fe, Cu, Zn
, Mn, and P. Role of metal ions present in biological systems with special reference to Na+, K+ and
Mg2+ ions: Na/K pump. Role of Mg2+ ions in energy production and chlorophyll. Role of Ca2+ in
blood clotting, stabilization of protein structures and structural role (bones).
Metalloporphyrins with special reference to haemoglobin and myoglobin, their biological functions,
Cooperative effect. Biological role of alkaline earth metal ions with special reference to Ca2+,
Nitrogen fixation and nitrogenase.
UNIT-3: Hard and Soft Acids and Bases & Non-Aqueous Solvents:
Classification of Acids and bases as hard and soft. Pearson’s HSAB principle and its limitations, acid-
base strength and hardness and softness. Symbiosis, theoretical basis of hardness and softness –
electronic, bonding theory, Drago- Wayland theory. Electro negativity and hardness and softness,
donor- acceptor number.
Non-aqueous Solvents:
Physical properties of a solvent, types of solvents and their general characteristics. Reaction in non-
aqueous solvents with reference to liquid NH3 and SO2. Properties of Solvated electrons.
Section B: Organic Chemistry-4 (30 Lectures)
UNIT-4: Polynuclear and heteronuclear aromatic compounds:
Polynuclear hydrocarbons: Synthesis, Properties, electrophilic substitution and structure eluciditation
of Naphthalene and Anthracene.
Heterocyclics: Synthesis, properties, basic character, molecular orbital pictures and aromatic
characteristics of Furan, Pyrrole, Thiophene, and Pyridine.
Condensed Heterocyclics: Synthesis of Indole by Fische - Indole Synthesis and Iso-quinoline by
Bischler-Napieralaski synthesis, Quinoline-Skraup synthesis, reactions, structure eluciditation.
UNIT-5 : Synthetic Polymer:
Addition or chain growth polymerization: Free radical and ionic Vinyl polymerization, Ziegler – Natta
polymerization. Condensation or Step growth polymerization: Polyester- Preparation and uses of
Dacron and Glyptal . Polyamides – Preparation and uses of Nylon-66 and Nylon-6 (Perlon). Phenol
formaldehyde resins- Preparation and uses of Novolak and Bakelite, Urea formaldehyde resins.
UNIT-6: Chemistry of Natural Products:
Alkaloids and Terpenes: Sources, classification, characteristics, isolation and general method of
structure elucidation of alkaloids. Structure eluciditation and synthesis of Nicotine.
Sources, classification, characteristics and isolation of Terpenes, Isoprene rule, special Isoprene rule
and Constitution and synthesis of Citral.

Reference Books:
1. James E. Huheey, Ellen Keiter & Richard Keiter: Inorganic Chemistry: Principles of Structure and
Reactivity, Pearson Publication.
2. J.D. Lee: A New Concise Inorganic Chemistry, E.L.B.S.
3. F.A. Cotton & G. Wilkinson: Basic Inorganic Chemistry, John Wiley & Sons.
4. T. W. Graham Solomons: Organic Chemistry, John Wiley and Sons.
5. I.L. Finar: Organic Chemistry, Vol. I, E. L. B. S.
6. R. T. Morrison & R. N. Boyd: Organic Chemistry, Prentice Hall.
7. Organic Chemistry, Dhawan, Pradeep Publication, Jallandar

DSE: - 2, LAB COURSE, CH- DSE-162 60 Lectures

Section A: Inorganic Chemistry
1. Separation of mixtures by paper chromatography: Measure the Rf value in each case. (Combination
of two ions to be given) chromatographic separation of Fe3+, A13+ and Cr3+
2. Paper chromatographic separation of Ni2+, Co2+, Mn2+ and Zn2+ or Anions
3. Preparation of following complexes and measurement of conductivity:
(i) Tetraamminecarbonatocobalt (III) nitrate
(ii) Tetraamminecopper (II) sulphate
(iii) Potassium trioxalatoferrate (III) trihydrate
(iv) Sodium trioxalato ferrate (III), [Na3 (Fe (C2O4)3]
(v) Cis- and Trans- bisoxalato diaqua chromate (III) ion
And others possibly by green methods
4. Compare the conductance of the complexes with that of M/1000 solution of NaCl, MgCl2 and LiCl3.
Section B: Organic Chemistry
Systematic Qualitative Analysis of binary organic mixture containing two solids, by detecting extra
elements using Green Reagents, identification of functional group, melting point, specific test and
preparation of one derivative. Separation with saturated NaHCO3 solution or Water

Reference Books:
1. A.I. Vogel: Qualitative Inorganic Analysis, Prentice Hall, 7th Edn.
2. A.I. Vogel: Quantitative Chemical Analysis, Prentice Hall, 6th Edn.
3. B.D. Khosla, Senior Practical Physical Chemistry, R. Chand & Co.
4. Vogel’s Qualitative Inorganic Analysis, A.I. Vogel, Prentice Hall, 7th Edition.
5. Practical Chemistry, Giri, Bajpai, Pandey; S. Chand . 2011
6. Lab Mannual of Organic Chemistry, R. K. Bansal, New Age, 2009
7. Systemic Practical Chemistry, P.C.Kamboj, Vishal Publishing Co, Jallandhar, 2011
8. Ahluwalia, V.K. & Aggarwal, R. Comprehensive Practical Organic Chemistry, Universities Press.
 Skill Enhancement Courses in Chemistry
SEC- I
Organic Spectroscopy
(Credits: 04, 30 Lectures, Time: 3 Hrs , MM 70 )
Note:
a) Ten compulsory objective type questions of one mark each, 10 x 1 = 10 Marks
b) Examinees to solve four short answer questions out of eight (two from each unit).4 x 5 =20 Marks.
c) Examinees to solve four long answer questions out of eight(two from each unit)..4 x 10 =40Marks
UNIT-1: Ultraviolet -Visible absorption spectroscopy: (8 Hrs) Merits of spectroscopic analysis,
Electromagnetic radiation, Wavelength, frequency, wave number and their relation, Absorption
spectra, absorbance, Absorption laws-Beer’s, Lambert Law and Beer-Lambert Law, molar
absorptivity, Presentation of UV spectra, types of electronic transitions, Concept of chromophore and
auxochrome, Effect of solvents ( polarity) and conjugation on absorption maxima, Bathochromic (
Red Shift), hypsochromic ( Bue Shift), hyperchromic and hypochromic effect , UV spectra of dienes
and Woodward – Fieser Rules , Applications of UV- visible spectroscopy
UNIT-2: Infrared (IR) absorption spectroscopy: (08 Hrs)
Introduction, Ir active and in-active molecules, Molecular vibrations - stretching and bending
vibrations, Fundamental bands, Vibrational transitions and degree of freedom, Hookes Law, selection
rules, intensity and position of IR bands, Factors affecting vibrational frequencies, Fermi resonance,
Instrumentation, measurement of IR spectrum, solvents, Functional Groups region, fingerprint region,
Characteristic absorptions of various functional groups, Interpretation of IR spectra of simple organic
compounds, Applications of IR spectroscopy.

UNIT-3: Nuclear Magnetic Resonance Spectroscopy (NMR): ( 10 Hrs) Principle of Proton

magnetic resonance spectroscopy, Origin of Signal, Number signals- equivalent and non-equivalent
protons, Position of signals - shielding and deshielding of protons, Peak area and proton counting ,
Chemical shift, units, scales, δ values of different types of protons, factors affecting δ., Splitting of
Signals - Spin – Spin Coupling ,coupling constants, magnetic equivalence of protons, Applications of
NMR Spectroscopy. Interpretation of PMR spectra of ethanol, acetaldehyde, ethyl bromide, n-propyl
bromide, isopropyl bromide, 1, 1-dibromoethane, 1, 1, 2- tribromoethane, etyl acetate, toluene,
benzaldehyde and acetophenone.

UNIT-4: Structure Elucidation: Structure elucidation of organic molecules on the basis of Spectral
data, chemical properties and molecular weight..

Recommended Text:
Morrison, R.T. and Boyd, R.T.; Organic Chemistry, Pearson Education
Soloman, Fundamentals of Organic Chemistry, Wiley
Dhawan, Organic Chemistry, Vol III, Pradeep Publication
Y.R. Sharma, Spectroscopy, S. Chand Co, New Delhi
Jagdamba Singh, UGC Organic Chemistry Vol III, Pragati Prakashan , Meerut
Jagmohan; Organic Spectroscopy,