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org/articles/meningothelial-meningioma
Meningothelial meningioma (also known as syncytial or endothelial meningiomas) is the most common
histological subtype of meningioma, found in ~60% of all meningiomas, most frequently combined with fibrous
meningioma (40%) or in isolation (17%) 1.
Their epidemiology, clinical presentation, radiographic features, treatment, prognosis, and differential diagnosis
are therefore discussed in the main article (see meningioma) and are not repeated here.
Pathology
Meningothelial meningiomas most closely resemble arachnoid cap cells and are characterized by sheets,
whorls or syncytia of neoplastic cells which have round or oval centrally located nuclei with dispersed
chromatin, smooth nuclear profiles and small indistinct nucleoli. They also sometimes demonstrate eosinophilic
cytoplasmic invaginations (a.k.a. intranuclear pseudoinclusions) 2-3. Lobules of the tumor are separated from
each other with collagen sheets 3.
References
1. Backer-Grøndahl T, Moen BH, Torp SH. The histopathological spectrum of human meningiomas.
Int J Clin Exp Pathol. 2012;5 (3): 231-42. Free text at pubmed - Pubmed citation
2. Cancer Grading Manual. Springer. (2007) ISBN:0387337512. Read it at Google Books - Find it at
Amazon
3. Lee JH. Meningiomas. Springer. (2008) ISBN:1846287847. Read it at Google Books - Find it at
Amazon
Dural masses
dural masses
o meningioma
grading and histological variants
grade I
meningothelial meningioma
fibrous meningioma
microcystic meningioma
psammomatous meningioma
angiomatous meningioma
secretory meningioma
metaplastic meningioma
cartilaginous meningioma
lipomatous meningioma
melanotic meningioma
myxoid meningioma
osseous meningioma
xanthomatous meningioma
lymphoplasmacyte-rich meningioma
grade II
clear cell meningioma
chordoid meningioma
atypical meningioma
grade III
rhabdoid meningioma
papillary meningioma
anaplastic meningioma (a.k.a. malignant meningioma)
imaging signs
CSF cleft sign
dural tail
ginkgo leaf sign (spinal meningioma)
mother in law sign
spoke wheel sign
sunburst sign
white matter buckling sign
variants
cystic meningioma
en plaque meningioma
radiation-induced meningioma
burnt out meningioma
by location
primary intradural meningioma
intraventricular meningioma
optic nerve meningioma
spinal meningioma
primary extradural meningiomas
primary intraosseous meningioma
Simpson grade (of resection)
o hemangiopericytoma
o solitary fibrous tumor of the dura
o primary dural lymphoma
o Rosai-Dorfman disease
o EBV-associated smooth muscle tumor
o meningeal melanocytoma
o primary meningeal malignant melanoma
o Erdheim-Chester disease
o sarcoidosis
o dural metastases
o hypertrophic pachymeningitis
tuberculous pachymeningitis
IgG4-related hypertrophic pachymeningitis