Odd Semester, 2017-18

INSTRUCTIONAL PLAN
L T P: 3-1-0 Credits: 4
CHB-211: Organic Chemistry-1
Faculty: Dr. Preeti Jain

Lecture Topic(s) Reference and

No. Chapter
Unit 1 : Mechanism of Organic reactions
1(a) Introduction: Reactions, attacking reagents, reactive
Ref.3 Chap 3(62-
intermediate, their types
68)
2(a) Carbocations, Carbanion: Structure, types, stability, reactions
Ref.5Chap 5(165-
3(a) Free radical, Carbenes: Structure, types, stability and reactions
204)
4(b) Nitrenes, Benzyne: Structure, stability and reactions
5(b) Addition reactions: Mechanism, examples and applications Ref.5,Chap15
(734-758)
6(b) Substitution reactions: Mechanism of SN1 and SN2 reaction, Ref.5,Chap 10
Energy profile diagram, factors affecting rate of reaction (293-354)
7(c) Elimination reaction: Mechanism of E1& E2 reactions, examples Ref.5, Chap17
and factors affecting rate of reaction, substitution v/s elimination (982-1005),
8(c) Rearrangements reactions: Mechanism and examples of Ref.5, Chap 18
rearrangement reactions. (1052-1068)
Ref.4(105-106)
Unit 2 : Alkanes
9 (a) Introduction: Alkanes, nomenclature, classification
10(a) Synthesis of alkanes: Wurtz reaction, mechanism, limitations Ref.3, Chap.
11(b) Synthesis of alkanes: Kolbe reaction, mechanism, limitations (pg.177-179)
13(b) Synthesis of alkanes: Corey-House reaction, mechanism Ref.1, Chap.
14© Synthesis by decarboxylation of carboxylic acid, mechanism, (pg.75-78)
limitations
15© Physical properties of alkanes Ref.1, Chap(pg. 85-
16© Chemical reactions of alkanes:Halogenation of alkanes 86)
Ref.3, Chap
(pg.181-184)
Unit 3 : Alkenes and alkynes
17(a) Synthesis of alkenes: Dehydration of alcohols and Ref.3 Chap.
dehydrohalogenation of alkyl halides (pg.208-210)
18(a) Saytzeff rule and Hoffmann elimination
19(a) Chemical reactions: Mechanism of hydrogenation, Electrophilic Ref.4, Chap 9,
and free radical additions, Markownikoff’s rule (pg.359-396),
21(b) Hydroboration oxidation, hydroxylation, Oxidation with KMnO4 Ref.3chap. (214-
Oxymercuration- reduction, epoxidation, ozonolysis, hydration 217)
Ref.4,Chap.13(517)
 22(b) Alkynes: Synthesis of alkynes Ref.3chap (234-
23© Chemical reactions: Mechanism of electrophilic and nucleophilic 240), Ref,4 Chap.
addition (470-474)
24© Hydroboration oxidation, Metal ammonia reductions
25© Oxidation and polymerization
Unit-4:Arenes
26(a) Structure of benzene, Molecular formula and Kekule structure,
Ref.4Chap. (530-
Stability and carbon-carbon bond length of benzene
540)
27(a) Resonance structure, Aromaticity:TheHuckelrule;Aromatic ions
28(a) Aromatic electrophilic substitution: Mechanicsm of nitration, Ref. 4 Chap. (561-
halogenation, 565), Ref.3 Chap.
29(b) sulphonation, mercuration and Friedel-Crafts reaction (608-611)

30(b) Activation/deactivation of the aromatic ring and directive effects Ref.3 Chap (625-
of the groups. 632)

31© Preparation and reactions of toluene

32© Preparation and reaction of naphthalene and anthracene.

Unit 5 : Alkyl and Aryl Halides

33(a) Alkyl halides: Synthesis
34(a) Mechanism of nucleophilic substitution reaction of alkyl halides
SN2 and SN1 reaction
35(a) Energy profile diagram of SN1 & SN2 and mechanism of SNi
reactions
36(b) Aryl halides: Synthesis
Ref.3 Chap-6,7
37(b) Chemical reactions:nuclear and side chain reactions
38© Addition-elimination and elimination-addition mechanism of
nucleophilic aromatic substitution reactions
39© Mechanism of electrophilic aromatic substitution:halogenations,
nitration
40© Friedel-Crafts alkylation/acylation, sulphonation reactions

Reference Books -
1. Organic Chemistry Volume 1 and 2 by I. L. Finar
2. Organic Chemistry by Pine
3. Advanced Organic Chemistry by Bahl and Bahl
4. Organic Chemistry by Morrison and Boyd.
5. Advanced Organic Chemistry by Jerry March