PATHOPHYSIOLOGY

Predisposing Factors

1. Work
Mutation of normal Precipitating Factors
2. Stress cells (Glial cells)
1. Stress

Formation of cancer cells

Normal cells affected-

Hgb: 110; hct: 0.33
deprivation of nutrients>>
Number and growth of abnormal cells (CBC);
Anemia

Hypertrophy of gliomal layer Compression of the

MRI results: Large
frontoparieto-temporal area
heterogenousity enhancing
of the brain
intraaxial mass at the left
TUMOR formation
Frontoparieto-temporal
region
Neurosensory changes: visual
Intracranial pressure changes, inappropriate
responses and memory lapses

Depletion of O2 and Hypo perfusion in

Nutrients cerebral circulation Restlessness,
Irritability, Anxiety

Lactic acid formation Capillary Refill Permeability

Headache, swelling of
Formation of Edema the affected area,
Swelling of Vomiting, Nausea,
cerebral cells Dizziness

Damage to
cells

Persistent
depletion of O2 Acidity in COMATOSE
and nutrients cellular and State
tissue level Metabolic Acidosis

DEATH Multiple Organ Dysfunction

Syndromes (MODS)

UNIVERSITY OF SANTO TOMAS

COLLEGE OF NURSING
Espana Boulevard, Sampaloc, Manila, Philippines 1015
Tel. No 406-1611 loc.8241 | Telefax: 731-5738 | Website: www.ust.edu.p