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interpretation [cytology]
Bacterial Casts
Bacterial casts are casts composed of
bacteria in a protein (hyaline) matrix. The
bacteria might be closely packed,
coarse yellow-brown granules of hemo- of casts of all types indicates renal in-
Suggested Reading siderin stain blue with a Prussian blue volvement. Casts represent different dis-
College of American Pathologists. Surveys stain for iron. Hemosiderin granules may ease states; eg, RBC casts are most
Hematology Glossary. Northfield, IL: College also be seen in the urine sediment, either associated with glomerular disease,
of American Pathologists; 1999. free or within macrophages or renal ep- whereas WBC casts are indicative of
Haber MH. Urinary Sediment: A Textbook ithelial cells, as the result of intravascular tubular disease, especially infection and
Atlas. Chicago, IL: ASCP Press; 1981. hemolysis. acute pyelonephritis. Casts must be
Finally, crystal casts of various uri- properly identified so that meaningful
Henry JB, Lauzon RL, Schumann GB. Basic
examination of urine. In: Henry JB, ed. nary crystals have been described. There diagnoses can be made.
Clinical Diagnosis and Management by is disagreement about whether they are
Laboratory Methods. 19th ed. Philadelphia, casts or merely crystals adhering to a 1. Rose BD, Rennke HG. Renal Pathophysiology—
193