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Dr. Avula Laxmaiah, MBBS, DPH, MPH, Ph.D, MBA, PG
Certificate in Applied Nutrition
Scientist ‘F’ & Head, Division of Community studies
National Institute of Nutrition, ICMR
Hyderabad‐500 007
Phones: 91‐040‐27019141,
Mobile : 09395113419
E‐ Mail: avulalaxman@yahoo.com/laxmanavula09@gmail.com
Role of Nutrition assessment
¾ Epidemiological data support that the
association between anthropometric measurements
and morbidity and mortality.
¾ Undernutrition – Low resistance – frequent infections.
¾ Obesity and overweight is also associated with
increased risk of developing cancer of the breast, colon,
pancreas, endometrium, gallbladder, esophagus, kidney.
¾ Assessment of nutritional status is essential for early
detection of undernutrition and at risk population in
the community.
¾ In fact, anthropometry started with the use of
ergonomics.
ERGONOMICS
HEIGHT OF DOORWAY WIDTH OF A CHAIR
LEVEL OF DOOR HANDLE
LEVEL OF DOOR HANDLE
How to assess nutritional status?
• Anthropometric measurements
• Bio-chemical estimations
• Clinical examination
• Dietary intake methods
• Energy requirements (Biophysical measurements)
Anthropometrics Measurements
Height (Cm)
Weight (Kg)
Head, Chest, Mid Upper Arm, waist and Hip
Circumferences (Cm)
Fat fold thickness (mm) at Triceps, Biceps, Sub‐scapular
and supra‐iliac sites.
Age Assessment
Accurate age assessment is very essential to compare
the measurements with age standard references,
especially in case of pre‐school children. Age
assessment is very difficult in rural and tribal areas.
The following methods will be useful:
Horoscopy,
Birth certificate
Immunization cards
Delivery notes
Local events calendar
Equipment required
Measurement of Weight
(Spring and beam balances are available)
Children: Salter balance, TANSI, SECA (electronic)
Adults : Sattilan, SECA, SECA & Autco electronic
Measurement of Height
Adults and Children ≥ 2 years
‐ 4 piece Anthropometric rod (up to 190 Cms)
Under 2 years children
Height will be measured With help of Infantometer (
up to 100 Cm)
Equipment required (Contd.)
Measurement of MUAC: ‐Fiber reinforced non‐elastic tape.
Fat Fold Thickness : ‐Holtain, Harpenden’s, UNA calipers,
Body Fat Measurement :‐ % of total Body Fat (Anthropometry)
: ‐ Bioelectric Impedance Assessment (BIA)
: ‐ DEXA (Duel Energy X‐Ray Absorptiometry)
:‐ Under water weight (Gold standard)
Criteria and identification of ‘At Risk
children’
• Criteria used for identification of At Risk
children is by growth monitoring.
• Growth monitoring involves
– ‐ Regular weighing children
– ‐ 0‐3 years, every month
– ‐ 3‐6 yrs, every 3 months
Techniques and Tools for GM
• Weighing scales
• Weigh baskets/slings
• Growth charts
• Community growth charts
Current status of Growth Monitoring
• Currently ICDS is using growth charts developed based
on Harvard standards as per the recommendation of IAP.
• The ICDS nutritional grades are Normal, Grade I, Grade
II, Grade III & Grade IV (Mild, moderate, severe and very
severe respectively).
• While internationally normal, underweight and
severely underweight classification is used.
• Therefore, our ICDS nutrition data is not useful for
international comparison.
IAP CLASSIFICATION
(Weight For Age)
NORMAL(M‐1SD) : > 80%of MED
GRADE I (‐1SD‐2SD) : 71‐80% MILD
GRADE II (‐2SD‐3SD) : 61‐70%MODER
GRADE III (‐3SD‐4SD) : 51‐60%SEVERE GRADE IV
(<4SD) : <50% VERY SEVERE
In 1966, a simplified combined‐sexes version of
Harvard growth curves – Reference (WHO)
ICDS IAP (Percentage of Median of Harvard Standards)
NCHS & HARVARD – SAME for < 5 Years
NFHS Standard Deviation
NNMB
Nutrition Surveys ‐3 SD = 67% instead 60% IAP
‐2 SD = 78% instead 80 % IAP
It means SEVERELY MALNOURISHED= (UNDERESTIMATION) and Malnutrition =
OVERESTIMATION
Mechanical weighing scale Digital weighing scale
Measuring child height with
Anthropometer rod
Equipment required (Contd.)
Measurement of MUAC : Fiber reinforced non‐
elastic tape.
Fat Fold Thickness : Holtain, Harpendens, UNA
calipers,
Measuring mid arm circumference with fiber‐ Measuring length of < 2 year child
reinforced inelastic measuring tape Using Infantometer
Measuring fat fold thickness at biceps
with Holtain calipers
References and Standards
References:
‐ Harvard Reference values
‐ NCHS Reference values
‐ ICMR Reference values
Standards:
‐ WHO new child growth standards 2006
Presentation
Preschool Children:
of Anthropometrics data
Using weights and heights, nutritional grades can be
computed according to Gomez, IAP and Standard
Deviation Classification.
Gomez classification
Severe III
8.00
V. Severe IV
6.00
4.00
2.00
0.00
0 3 6 9 12 15 18 21 24 27 30 33 36 39 42 45 48 51 54 57 60
Age in Months
80% of Median 70% of Median 60% of Median 50% of Median
Worldwide practices in child growth
monitoring
Reference population
Reference Countries
Number %
NCHS/WHO 99 68
Tanner 3 2
Harvard 13 9
Local 25 17
Other 17 12
Unknown 6 4
• Harvard references were developed based on the
anthropometric data of only one nation, then
applicability is big question?
• The ICDS data is not useful for international
comparison, because internationally standard
deviation (SD) classification is being used.
• Therefore, there is need to switch over to SD
classification by using WHO new child growth
standards.
Need for New Standards
• Exclusive breast feeding for six months is normative
for growth and development.
• Earlier standards are based on infants receiving
bottle and mixed feeding.
• We should know how children should grow but not
how they are growing.
• Children below six years have same potential to
grow and develop as long as their basic needs of
nutrition, environment and health are met.
• The boys and girls grow differently.
20.0
B
18.0
Graph shows how Boys and Girls grow differently G
16.0
14.0 B
G
B
12.0 G
10.0
8.0
6.0
4.0
2.0
0.0
0 3 6 9 12 15 18 21 24 27 30 33 36 39 42 45 48 51 54 57 60
WHO MED BOYS WHO MED GIRLS WHO 2SD BOYS WHO 2SD GIRLS WHO 3SD BOYS WHO 3SD GIRLS
New Standards versus Old Standards
• New Standards are based on breast fed
infants while old standards are based on
mixed feeding.
• Old standards are from one community while
new standards are from six different nations.
• New standards are sex specific while old
standards are unisex.
• New standards are based on S.D.
internationally accepted classification.
New Standards versus Old Standards
• Presently in ICDS Harvard Standards are used
specifying Normal, Grade I/II/ III & IV (Mild,
moderate, severe and very severe).
• While internationally normal, underweight and
severely underweight classification is used.
• New standards have prescriptive approach while
old standard has descriptive approach.
Rationale for promoting healthy growth
and development
Childhood morbidity
Childhood mortality
Childhood obesity
Child cognitive
development
Adult‐life consequences
WHO Child Growth Standards
The new
standards will
play a key role
in the
prevention and
early
recognition of
childhood
obesity
WHO Child Growth Standards
A growth
chart for
the 21st
Brazil
Ghana
India
Norway
Oman
80
USA
Mean of Length (cm)
70
60
50
Age (days)
Errors in Measurement
Inter individual variation
(Variation between two individual's measurements)
Intra‐individual variation
(Variation between two measurements taken by same individual)
Example: Height (variation <0.2Cm)
Weight (variation < 100g)
MUAC (variation < 0.2 Cm)
FFT (variation < 0.5mm)
Types of errors
Instrumental errors Random errors
Non‐random errors
Recording errors
Reading errors
What is BIAS?
To give a particular direction
To influence
To prejudice
To cut cloth on the bias
Inclined to one side
swelled on one side
Validity and Reliability
Validity is an expression of the degree to which a test is capable
of measuring what it is intended to measure.
A study is valid if its results corresponding to the truth, there
should be no systematic error and the random error should be as
small as possible.
Validity
High Low
Measured values Measured values
High
Reliability
(Repeatability)
Measured values Measured values
Low
RELATIONSHIP BETWEEN BMI AND
PERCENT BODY FAT AND FIXING ON BMI
CUT-OFFS FOR URBAN MEN AND WOMEN
• Studies have documented that relationship
between BMI and percent body fat varies
with age, gender and ethnicity. Moreover,
Asian Indians have higher fat mass at lower
BMI values than Caucasians.
Different superscripts indicate significantly different from others
Mean Anthropometric, Blood Pressure and
Bio chemical profile ‐ by income group‐ Females.
Parameter HIG(161) MIG(211) LIG(228) Pooled
Height (Cms) 156.4a 153.3b 152.3b 153.7
Weight (kgs) 66.2a 60.0b 55.8c 60.1
Waist Cir (Cms) 83.7a 80.1b 75.8c 79.5
Hip Cir (cms) 100.6a 96.4b 91.9c 95.9
BMI (kg/m2) 27.1a 25.6b 24.0c 25.4
WHR 0.83a 0.83a 0.83a 0.83
W-HtR 0.54a 0.52a 0.49b 0.52
% Body Fat 39.0a 34.8b 32.2c 34.9
Blood Pressure
Systolic 120a 120a 111a 119
Diastolic 77a 77a 78a 77
Lipid Profile
Fasting Blood glucose 110a 106a 103a 106
Serum Triglycerides 127a 107a 108a 112
Total Cholesterol 176a 169a 182a 169
Different superscripts indicate significantly different from others
Correlation between BMI and other Anthropometric measurements
** Significant at the 0.01 level
* Significant at the 0.05 level
Correlation between Anthropometric measurements and Lipid profile
** Significant at the 0.01 level
* Significant at the 0.05 level
ROC curve for BMI ‐Males
Area Under the Curve
Std. Asymptotic
Area Error(a) Sig.(b) Upper Bound Lower Bound
The test result variable(s): bmi has at least one tie between the positive actual
state group and the negative actual state group. Statistics may be biased.
a Under the nonparametric assumption
b Null hypothesis: true area = 0.5
Test accuracy
0.50‐0.75 –Fair
0.75‐0.92 –good
0.92‐0.97 –V.Good
0.97 ‐1.0 ‐excellent
ROC curve for waist circumference ‐Males
Area Under the Curve
Test accuracy
0.50‐0.75 –Fair
0.75‐0.92 –good
0.92‐0.97 –V.Good
0.97 ‐1.0 ‐excellent
Central obesity and Diabetes prevalence
Diabetes prevalence (%) %
insulin resistance:
30
30
South Asian
South Asian
susceptibility
20
20
10
10
European
000.8 0.9
0.8 0.9 11
McKeigue et al. Lancet, 1991, 337: 382 Waist // hip
hip ratio
Waist ratio
Area under curve with 95% confidence interval and
cut offs for body mass index, waist circumference for
25% Body fat among Men – Income groups pooled
Obesity AUC (95% CI) Cut off Sensitivity Specificity
index Points (%) (%)
20 99.2 28.6
21 96.5 46.9
*Optimal cut off point
Relationship Between BMI and Cardiovascular Disease
Mortality
3.0
2.6
Men
Relative Risk of Death
2.2
Women
1.8
1.4
1.0
Lean Overweight Obese
0.6
<18.5 20 25.0 30.0 >40.0
Body Mass index
Source: Calle et al. N Engl J Med 1999;341:1097.
Unadjusted Odds ratio (OR) with 95% CI for hypertension:
Kerala
Men Women
Variables
OR 95% OR 95%
Confidence Confidence
General obesity 2.6 1.89-3.61 2.43 1.92-3.09
(BMI)
Abdominal obesity 7.0 2.92-16.80 3.0 2.29-3.87
(WC)
Central obesity 2.2 1.83-2.66 2.07 1.69-2.53
(WHR)
Test accuracy
0.50‐0.75 –Fair
0.75‐0.92 –good
0.92‐0.97 –V.Good
0.97 ‐1.0 ‐excellent
ROC curve for waist circumference ‐Females
Area Under the Curve
Test accuracy
0.50‐0.75 –Fair
0.75‐0.92 –good
0.92‐0.97 –V.Good
0.97 ‐1.0 ‐excellent
Area under curve and Optimal cut offs for body mass index, waist
circumference for 30% Body fat among –women
income groups pooled
21 93.0 83.0
0.949
BMI (0.928- 22* 88.0 90.0
0.970) 23
80.1 93.0
24 70.9 97.0
70 90.7 85.7
73 84.9 96.9
*Optimal cut off point
SAME BMI 22.3 FOR BOTH OF THEM
Anthropometry and Lipid profile of hypertensive and
Normotensives‐ income groups pooled
Males Females
Anthropometry Htn Normal Test Htn Normal Test
(n=106) (n=325) sig (n=110) (n=486) sig
Height 166.8 166.0 P<0.001 152.7 153.9 P<0.005
Weight 74.6 68.3 P<0.001 66.6 58.7 P<0.001
BMI 26.7 24.2 P<0.001 28.6 24.7 P<0.001
%BF 29.5 24.8 P<0.001 38.6 34.2 P<0.001
LBM 52.4 50.8 NS 40.6 38.1 P<0.01
WC 95.9 87.5 P<0.001 87.4 77.7 P<0.001
WHR 0.99 0.94 P<0.001 0.86 0.82 P<0.001
W.Ht.R 0.58 0.52 P<0.001 0.57 0.50 P<0.001
Lipids
Fasting blood
133 105 P<0.001 129 102 P<0.001
glucose
Serum
213 163 P<0.05 124 110 NS
Triglycerides
Total cholesterol
181 168 NS 174 168 NS
Mean± SE of anthropometric, blood pressure and biochemical
parameters of individuals by percent body fat.
Anthropometry
BMI 21.6±0.220 26.9±0.238 P<0.001 19.1±0.239 26.7±0.197 P<0.001
WC 79.5±0.669 96.2±0.553 P<0.001 63.4±0.585 82.6±0.450 P<0.001
WHR 0.90±0.004 0.99±0.058 P<0.001 0.78±0.013 0.84±0.002 P<0.001
W.Ht.R 0.47±0.054 0.57±0.0552 P<0.001 0.41±0.003 0.53±0.003 P<0.001
Blood Pressure (mm/Hg)
Systolic 119±1.189 130±1.100 P<0.001 107±0.1336 121±0.895 P<0.001
Diastolic 79±0.0828 85±0.661 P<0.001 69±0.868 78±0.515 P<0.001
Lipid profile
Fasting blood
101.4±3.921 117.9±4.313 P<0.01 91.3±1.269 109.9±3.053 P<0.01
glucose
Triglycerides 159.0±18.658 185.6±10.629 NS 73.8±5.356 122.5±5.584 P<0.001
Total cholesterol 161.5±5.301 177.6±4.19 P<0.01 146.4±4.705 174.3±3.490 P<0.001
Mean± SE of blood pressure and biochemical
parameters of individuals by BMI
Anthropometric
Odd’s ratio with 95% CI
indices
Male Female
4.4 6.4
% Body Fat
(2.5-7.6) (2.3-17.9)
3.6
2.5
BMI (1.9-6.9)
(1.5-4.1)
2.7 4.3
WC
(1.6-4.7) (2.1-8.8)
HTN Vs WC, WHR, and BMI
(Odds Ratios with 95% CI )
2.6 2.2
WHR
(2.4 - 2.8) (2.0 - 2.4)
3.1 3.2
BMI
(2.7 - 3.5) (2.8 - 3.5)
3.8 4.6
WC
(2.7 - 5.3) (4.0 - 5.2)
DM & IGT Vs WC, WHR, and BMI
(Odds Ratios with 95% CI )
6.5 7.0
WC
(3.1 – 13.9) (4.3 – 11.6)
4.4 1.7
WHR
(2.9 – 6.5) (0.9 – 2.8)
2.5 3.8
BMI
(1.5 – 4.2) (2.5 – 6.0)
CONCLUSIONS
FMI= Fat Mass (kg)
{height (m)}2
Fat Free Mass Index
FFMI = Fat Free Mass (kg)
{height (m)}2
Area under the curve with optimal cut offs for
fat mass index using percent Body fat as standard
Gender AUC (95% CI) Cut off points Sensitivity (%) Specificity (%)
6.1* 90.0 92.0
6.2 88.0 92.6
0.976 (0.966- 6.3 87.7 93.1
Males
0.987) 6.4 85.8 94.9
6.5 83.5 96.0
6.6 83.1 98.1
6.1 98.0 88.0
6.2 97.4 91.0
6.3 97.0 92.0
0.992 (0.986- 6.4 96.6 93.0
Females
0.997) 6.5 96.0 94.0
6.6* 95.2 97.0
6.7 93.6 98.0
6.8 93.2 98.0
*Optimal cut off point
ROC curve for Fat Mass Index ‐ Males
Area under curve
0.976 ( 0.966‐0.987 )
Test accuracy
0.50‐0.75 –Fair
0.75‐0.92 –good
0.92‐0.97 –V.Good
0.97 ‐1.0 ‐excellent
ROC curve for Fat Mass Index ‐ Females
Area under curve
0992 ( 0.986‐0.997 )
Test accuracy
0.50‐0.75 –Fair
0.75‐0.92 –good
0.92‐0.97 –V.Good
0.97 ‐1.0 ‐excellent
Classification of Nutritional status (Schutz Y, etal 2002)
* low = below 5th centile and High = greater than 95th centile
GROWTH MONITORING
¾ It is necessary to find out whether the child is
growing normally as expected or not. This
process of observing growth of the child at
regular intervals (i.e. monthly or quarterly) is
called growth monitoring.
¾ Growth monitoring provides a visual record of
the growth pattern of the child.
USES OF GROWTH MONITORING
Using WHO Child Growth Standards