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Peptide

Hypotension (low blood volume) Atrial Natriuretic Factor (ANF)


Heart Atria
Hypertension (high blood volume)
Peptide
Gonadotropin releasing hormone (GnRH)
Hypothalamus release of FSH and LH
Erythropoietin
Renin Kidneys
Peptide
Antidiuretic hormone (ADH) "Vasopressin"
Steroid H2O reabsorption in collecting ducts
Posterior Pituitary uterine contractions; milk secretion
Cushing syndrom (hyperglycemia) Glucocorticoids Oxytocin "Relaxin"
e.g., cortisol
Inflammation, arthritis

Steroid Peptide
Adrenocorticotropic hormone (ACTH)
Conn's syndrom (high NaCl) Mineral corticoids Release of adrenal cortex hormones
e.g.g, aldosterone
Addison's disease (low NaCl) Peptide
Follicle stimulating hormone (FSH)
Steroid Estrogen release; spermatogenesis

Hair loss, impotence, prostate cancer Peptide


Testosterone androgens
Male feminization, infertility Growth hormone (GH) "Somatotropin" Gigantism (kids); acromegaly (adult)
Adrenal Glands Anterior Pituitary Dwarfism
Sex hormones
Breast cancer, uterine cancer
estrogens Melanocyte stimulating hormone (MSH) Peptide
female masculinization, infertility

mammary growth during pregnancy Peptide


Prolactin (PRL)
progesterone Milk production in mammary glands
infertility
Peptide
Amino Acid Thyroid stimulating hormone (TSH)
Release of thyroid hormones
epinephrine & norepinephrine
Catecholamines
Manic episodes, hypertension
Endocrine System Amino Acid Made from Tryptophan
Depression, lethargy
Melatonin Delayed sexual maturity
Pineal Gland
Peptide Precocious sexual maturity
from alpha cells
Glucagon
high blood glucose Peptide
low blood glucose Calcitonin inadequate blood calcium (tetany)
Peptide decreased bone calcium
from beta cells
Insulin Pancreas (islets of Langerhans) Amino Acid
insulin shock; coma (hypoglycemia)
Triiodothyronine (T3) Hyperthyroidism (Grave's disease)
diabetes mellitus Thyroid Gland
cretinism (kids), myxedema
Peptide
Amino Acid
from delta cells Somatostatin
Tetraiodothyronin (T4) / Thyroxine Exophthalamic goiter
inhibits release of growth hormone
iodine deficient goiter (adults)

Steroid
Testosterone Peptide
from interstitial cells of Leydig Testes
Parathyroid hormone / Parathormone Decreased bone calcium
Parathyroid Glands
Inadequate blood calcium
Steroid
Estrogens
e.g., estradiol from ovarian follicle

Steroid Ovaries Peptide


Progesterone Thymosin
from the corpus luteum Thymus Gland Maturation of T-cells

Peptide
Human chorionic gonadotropin (HCG)
progesterone and estrogen secretion Placenta

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