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ANNEX 1

HUMAN BINGO
ACTIVITY
Objectives:

At the end of the activity, participants should be able to:

 identify their specific traits;


 explain how genes are being transferred from parents to offspring; and
 show the importance of camaraderie in getting to know other persons.

Materials:

 Human Bingo Activity Sheet


 Pen

Procedures:

1. On the Human Activity Sheet, each square has something like “has curly hair,
straight hair, continuous hairline,
2. Everyone must walk around and get others to initial a square that pertains to their
specific traits.
3. If there is unique or distinct trait among the others, let him or her sign in the
square allotted in the middle of the Human Bingo Activity Sheet.
4. Get the names of participants who have various traits.

Guide questions:

1. Why do you have those traits?


2. Why do think these traits vary from one person to another?
3. How these happen?
4. What is responsible in passing these traits from parental generation to the next
filial generation?
5. How genes related to DNA?
HUMAN BINGO HUMAN BINGO
ACTIVITY SHEET ACTIVITY SHEET
Name: __________________________________ Name: __________________________________

Continuous Tongue Rolling Widow’s Peak Continuous Tongue Rolling Widow’s Peak
Hairline Hairline

Free Earlobe Others Attached Free Earlobe Others Attached


Earlobe Earlobe

Straight Hair Non-Tongue Curly Hair Straight Hair Non-Tongue Curly Hair
Rolling Rolling

HUMAN BINGO HUMAN BINGO


ACTIVITY SHEET ACTIVITY SHEET
Name: __________________________________ Name: __________________________________

Continuous Tongue Rolling Widow’s Peak Continuous Tongue Rolling Widow’s Peak
Hairline Hairline

Free Earlobe Others Attached Free Earlobe Others Attached


Earlobe Earlobe

Straight Hair Non-Tongue Curly Hair Straight Hair Non-Tongue Curly Hair
Rolling Rolling
ANNEX 2

ANTICIPATION GUDE

BEFORE AFTER
STATEMENT
AGREE DISAGREE AGREE DISAGREE
1. DNA is a biomolecule that
forms a double helix structure in
living organisms.
2. DNA is responsible for
determining the specific
characteristics of an organism.
3. Each nucleotide of DNA
contains sugar, a phosphate
group, and one nitrogenous
base.
4. Nucleotides are the basic
building blocks of DNA
5. The four bases of a
nucleotide are the adenine,
uracil, guanine, thymine
ANNEX 3

DNA Modeling
Objectives
 Identify the components of a DNA molecule
 Construct a model of a molecule of DNA

Materials
 Cutouts of basic subunits of DNA
 Crayons
 Scissors
 Tape or glue

Procedure

1. Cut out all the units needed to make the nucleotides from the
handout provided.
2. Color code the nitrogenous bases, phosphorus, and sugars
according to the teacher’s directions.
Adenine = yellow Guanine = green
Thymine = blue Cytosine = red
Phosphate = brown Deoxyribose = black
3. Using the small squares and stars as guides, line up the bases,
phosphates and sugars.
4. Now glue the appropriate parts together forming nucleotides.
Construct DNA model using the following sequence to form a row
from top to bottom:
Thymine
Adenine
Cytosine
Guanine
Adenine
Cytosine
5. Let this arrangement represent the left half of your DNA
molecule.
6. Complete the right side of the ladder by adding the complementary
bases. You will have to turn them down in order to fit.
7. Your finished model should look like a ladder.
Guide Questions:

1. What are the common parts of a nucleotide?


2. What is the one part of the nucleotide that differs among the other
different nucleotides?
3. List the different kinds of nitrogen bases.
4. Are there always going to be an equal number of adenine and
thymine nucleotides in molecule? Why?
5. Are there always going to be an equal number of guanine and
cytosine nucleotides in a molecule? Why?
6. The sides of the ladder are made up of alternating _______and
_______ molecules. The steps (or rungs) of the ladder are
made up of ________ held together by hydrogen bonds.
ANNEX 4 A

Origami DNA

Objectives:

At the end of the activity, participants should be able to:


 Identify the components of a DNA molecule
 Construct a 3D model of DNA

Materials:
 Blank DNA origami template
 Crayons
 Scissors
 Tape or glue

Procedure
1. Lay out the blank DNA origami template on the table.
2. Start by writing the first letter of your DNA sequence (A, C, G or T) in the top
right corner.
3. Continue your sequence down the column on the right.
4. Write the corresponding complementary bases in boxes diagonally across from
your sequence.
5. Continue the complementary sequence until you reach the bottom; and fill in the
top box of that column with the corresponding complementary bases.
6. That’s it! Now you are ready to color and fold your DNA!

Guide Questions:
1. What base does adenine pair with?
2. What base does guanine pair with?
3. Describe the shape of the DNA molecule.
4. What are the three components of a nucleotide?
5. Suppose you know that the sequence of bases on one DNA strand (one side of
the DNA ladder) is AGCTCAG. What is the sequence of the bases on the
opposite strand?
6. Assume that a 100-base pair DNA double helix contains 45 cytosine’s. How
many adenines are there?
ANNEX 4 B

HAVE YOUR DNA AND EAT IT TOO

Objectives:

At the end of the activity, participants should be able to:

 identify parts of nucleotides;


 make an edible DNA model.

Materials:

 2 pieces of licorice
 12 toothpicks
 9 pink marshmallows
 9 yellow marshmallows
 9 green marshmallows
 9 orange marshmallows
 5 paperclips
 Masking Tape

Procedures:

Step 1: Choose one of the sequences below.

Sequence 1: T A C G T A T G A A A C -or-
Sequence 2: T G G T T T A G A A T T

Step 2: Assemble one side of your DNA molecule. A piece of licorice willform the
backbone and marshmallow swill be the chemical bases. Place a marshmallow on the
end of a toothpick so that the point of the toothpick goes all the way through. Anchor the
toothpick into the licorice backbone.

Step 3: Label the backbone. With a marker or pen and masking tape, label your
licorice backbone “DNA- 1” or “DNA-2” depending on which sequence you used. Write
the label on the left end of the licorice.

Step 4: Match the chemical base pairs. Place the color marshmallow for the matching
chemical base on the other end of each toothpick. Remember that A always pairs with
T and C always pairs with G!

Step 5: Complete your DNA model. Attach the other backbone so your model looks
like a ladder.
Step 6: Twist your DNA model. Carefully twist your DNA molecule so that it looks like
a double helix.

Step 7: Label your model. Make flags to label the parts of your DNA out of paper clips
and tape. Label one of each o fthe following: Adenine, Thymine, Cytosine, Guanine,
and Backbone. Make sure your chemical base pairs are correct!

Guide questions:
1. What are the common parts of a nucleotide?
2. What is the one part of the nucleotide that differs among the other different
nucleotides?
3. What are the different kinds of nitrogen bases?
4. Are there always going to be an equal number of adenine and thymine
nucleotides in molecule? Why?
5. Are there always going to be an equal number of guanine and cytosine
nucleotides in a molecule? Why?
6. The sides of the ladder are made up of alternating _______and_________
molecules.
The steps (or rungs) of the ladder are made up of _______ held together by
hydrogen bonds.
ANNEX 5 BOX LIST ORGANIZER
ANNEX 6 (Please see a folder for the copy per group to be printed separately)