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QUESTIONS
Q#1 Name the class of Diuretics that act on this part of the tubule.
Q#2 Name two drugs that block the channel marked with an arrow.
Q#3 What is the major advantage of this class compared to other diuretics?
Q#4 Which hormone acts on this part of the tubule?
Q#5 What are the two major side-effects of this drug?
KEY:
QUESTIONS
Q#1 What class of Diuretics acts on the channel marked with an arrow?
Q#2 Name two Diuretics in this class.
Q#3 Give two major side effects of this class.
Q#4 Name two clinical indications for this class.
Q#5 Why this class of diuretics is more effective than the others?
KEY:
Q#2 Inhibit coupled Na/K/2Cl cotransporter pump in the luminal membrane of thick ascending limb of loop of
Henle. Increase in renal blood flow. Increase renal excretion of K and H.
QUESTIONS
Q#1 What class of Diuretics acts on the channel marked with an arrow?
Q#4 Name two clinical indications for the use of these diuretics
KEY:
Q#1 Thiazide Diuretics 1
QUESTIONS
Q#1 Identify the class of the drug that acts on the enzyme marked with an arrow?
Q#4 What are the two main side-effects of this class of drugs?
KEY:
Q#1 Carbonic Anhydrase Inhibitors.
Q#3 Glaucoma, Urine Alkalinization, Metabolic Alkalosis, Acute Mountain Sickness, Hypokalemic
Periodic Paralysis.
Q#4 Hyperchloremic Metabolic Acidosis, Renal Stones, Renal Potassium wasting, Allergic Reactions,
Drowsiness and Paresthesias.
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QUESTIONS
Q#1 What class of Diuretics acts on the channel marked with an arrow?
Q#5 Why this class of diuretics is more effective than the others?
KEY:
Q#4 Hyperkalemia. Acute Heart Failure, Acute Renal Failure, Anion Overdose. 1
Q#5 Because they diminish the maximum concentrating capability of the kidney. 1
QUESTIONS:
KEY:
Q#2 Glaucoma. Urinary alkalinization. Metabolic alkalosis. Acute mountain sickness. Epilepsy. Hypokalemic
periodic paralysis. To increase urinary phosphate excretion in severe hyperphosphatemia
Q#3 Hyperchloremic metabolic acidosis. Renal stones (phosphate, hypercalciuria). Increase potassium excretion.
Drowsiness, paresthesias.Hypersensitivity reactions
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