MedTech and Tech 2018

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Reducing Hospital Infections through Robotic Tech.

HAI’s are the 4th leading cause of death i the us

Only half of freq. Touched surfaces are properly cleaned
Don’t use on humans
Robot:
PUlsed Xenon UV Lamp
Protected bulb
Light only penetrates 4mm deep
Touchscreen interface
Sends info to to maker
Stats on hospital cleanliness
Radius of about 15ft around robot
Adds about 10mins to cleaning process
Each pulse is a different wavelength
Kills any single cell organism with DNA or RNA
Doesn’t affect plastic
The light breaks the backbone of Cells
Cells can’t become resistant to UV Light
Lyses a cell, killing it and not allowing it to mutate
The robot allows for a 39% decrease in CDI incidence
Standard in Mayo Clinic hospital

Cleaning is x16 more effective than traditional cleaning

100% reduction in VRE and MRSA from the environment
People carry the infections so the rate is not completely eradicated
“Overachiever”-bekah
“Not at al i just want to seem that way”-faith
“If it gets rid of skunk smell we need at bhs for weed”- bekah

Used in OR to keep surgical infection rate low

Used in patient rooms to keep bioburden low for long term patients
Used in NICU every 3 days (milk labs)

SUMMARY
HAL are dangerous and costly
Innovative UV tech is closing the gap in emerging infections and treatments to address such
Results reveal decreased infection and lower environmental risk

Future Uses?(My thoughts and presenter”s)

Human use
Faster times
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Smaller and better range
Could use in body for surgical areas
Automatic clean room
“:)”-bekah
Life expectancy
5yrs
$20,000 contract
Maintenance and bulb replacement

GENETICS

Genetic susceptibility to environmental factors

Lung cancer and smoking
CSTM1 null phenotype and susceptibility to lung cancer
Complex decision making smoking cessation
-DRD
TB Infections
NRAMP1 gene and susceptibility to TB
HIV Infections
Resistance with CCR5 mutations
OUtcome in head trauma
Changes in ApoE polymorphism- mimics Alzheimer's risks

Behavior patterns
50-70% of your behavior is determined by your genes

Dopamine is a simple molecule

Its production and destruction are under the control of enzymes , the structure of
which are dictated by genes
The dopamine receptor is “ polymorphic”

A VNTR in exon 3 is more likely to result in you cheating on your spouse

New Genetic tools

Big Data
SNP microarray
Using it instead of Oligonucleotides as probes
About 2.7 million
HIgh throughput sequencing
Buoo informatics fragment / multi sampling testing
NextGen sequencing
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Massively parallel sequencing
Exome Sequencing
Examining all coding region of the human genome
Whole Genome Sequencing
Cost ~$15-20,000
Takes about 26hrs
80% of the non coding DNa
Appear to be regulatory elements such as non-coding RNAs
Debated- especially among evolutionary biologist- as the definition of function

Improved Diagnostics
Family History
Can correctly interpreted can diagnosis half of all diagnosable conditions
and provide otherwise unknown information in those cases where genetic testing fails
NSIGHT
26hrs and $7,000 to test newborns and parents
Genomes in healthy Newborns
Newborn exome sequencing for universal screening
Not tied to NBS
Lots of ethic debates tied to this

Improved therapeutics
Personalized treatment
Almost no cancer treatment that doesn’t use genetics
Pharmagistics
The right drug for the right person

Genetic therapies
Replacement therapy
Modified stem cells (genomic specific)

Healthcare Cybersecurity​:
The industry the the highest number of attacks by ransomware ...
Most malicious domains about 60%...
There are around 24000 malicious mobile ...
The app cat with malicious issues are lifestyle apps ...
Between 15-17 the us was the country most affected...
Iot attacks wer up 600 percent in 2017...
The financial services industry ...

$160 billion is the cyber revenue

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Israel is a cyber software hotspot, both varonies and check point originate
HiPPA HIP(Health Information Privacy)-
https://www.ocrportal.hhs.gove/ocr/breach/breach_report.jsf

Patient records can sell for $300-$400 on the dark web, several hundreds of times more
valuable than stolen credit card info

Data for sale includes

Names, birth dates, policy numbers , diagnosis codes and billing info. Fraudsters use
this data to create fake ids to buy med equipment or drug to be resold

Most networks have been infiltrated at least 18 months

Protection levels are not as advanced as the threats

The 6 step HIPAA compliance checklist

Map your data
Determine who has access to HIPAA data
Monitor all file access to your data
Set up alerts using data security analytics
Protect the perimeter
Monitor activity on the perimeter and add threat models

Robotics in Orthopedic Surgery:

Using a CT scan they can build a 3d computer model that is then altered to proper needs
MAKO Robotics has solve the problem of a total Knee replacement
STRYKER made robotic arm and bought MAKO

DaVinci vs. MAKO

DaVinci
Laparoscopic- controlled by doctor

Mako
Adds a safety zone to prevent saw from damaging outside tissue
Increased Reproducibility
Decreased Variability
X-Rays look great
Precision placement of TKA components equals Increased longevity( with exceptions such as
trauma)

Australian Registry
Oslo Study
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Smith and Nephew “NAV10”
Zimmer-Biomet “ROSA”

EXOS:
Human physical performance
4 pillars of human performance
Mindset
Nutrition
Movement
Recovery

If you don’t do all of these you will be a one hit wonder, doing all of these will lead to success
over and over

Performance code
Learn
Design
Deliver
How to get ahead:
Behavioral Upgrade
We have to seek to each person's individual needs
Building skill sets for success
Having the autonomy to pick your own path to success
Cardiovascular Health
Upgrade VO2 and lactic uptake
MSK and Movement quality
Movement quality matters
Bad movement patterns lead to injury
Biomechanical pain is often an effect of bad form
Impacting local communities

Personalized Medicine and Cancer Genomics Testing:

Cancer is the 2nd leading cause of death

How cancer is developed
Genetic disease
Changes in the DNA regarding growth and duplication

BRCA mutations increase the risk of certain breast cancers

Nonsense mutation BRCA1 leads to a failure of fixing the issue
Cancer risk increases with age and other carcinogen intake
Target Therapy
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Focuses on fight the cancer cells while doing less damage to normal cells
Chemo
Can kill both healthy cells and cancer cells
Immunotherapy
T cell approaches cancer cell
T cell attacks cancer cell
Cancer cell destroyed
(Cancer isn’t destroyed by our body because our body thinks those cells are ok)
Boosts our own immune system to fight cancer(allows our body to recognize cancer
cells)

Tech Trends:

All types of the workforce are affected by technology

3-d printing skin
Casts

Demographics have changed

Average house hold size has decreased
Changes market
Younger people are less often married
Women hold up half the sky
Women on board of directors decline
The Remote control for LIfe
Meet Your BFF
We talk to robots more than actual people
Less than 1-3 of things require human support
Relying on Robots
How to replace labor with robots
IoT value Creation
Increase value of company
Operational Wearables
Exoskeleton to help construction worker
Visual and Video Search Rising
You can tell how old a person by how the search
AI adoption is just beginning
80% of enterprises already investing in AI
Machine Learning
Health Monitoring
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5G: Next Gen NEtworking
Everything connected in real time, all the time
Merged Reality
Training Employees
Autonomous Driving
It’s not about the car you are going to be in, but more marketing
How do companies jump into new business models no one has thought of before
Smart Cities
30% of cities worldwide are trying to figure out a smart city platform
ONly the paranoid survive
Autonomous and Electric Vehicles:

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