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History of 21st century science is bringing the benefits

Cordyceps of the remarkable Cordyceps mushroom to

thousands of people. The story of how one of

Cultivation
the Chinese emperors’ favorite herbal medica-
tions became available to everyone else.

While Cordyceps has been used for a
long time in Chinese and Tibetan medicine,
it was not until 1972 that the first success-
ful Cordyceps culture was isolated by the
Institute of Materia Medica of the Chinese
Academy of Sciences. This strain was isolated
not from Tibet, where most of the top qual-
ity Cordyceps comes from, but rather it was
isolated from a specimen found in Qinghai
province in Central China. This was the forth
culture that was isolated by this institute,
and named CS-4. The first three isolates did
not have the properties considered benefi-
cial in Cordyceps and so were never put into
commercial cultivation.
This CS4 culture was introduced in China
as a prescription medicine in 1988 under the
name Jin Shui Bao. As part of the approval
process to bring this drug to market, many
clinical and safety trials were conducted
showing efficacy and safety. That is why
there are so many scientific articles avail-
able on this particular strain called CS4. This
medicine has accumulated more than 20
years of clinical observation and the results
have been quite astounding. There are some
conditions for which Cordyceps has proven
to be the best possible choice.
But keep in mind the advances in sci-
ence over the last 37 years. That is how long
ago CS4 was isolated. Because CS4 was the
best possible option at that time, certainly
does not mean it is the best choice today.
Every aspect of science and technology has
advanced during that period. Virtually no
other medicine of that era is still consid-
ered first line defense against today’s health
threats, yet many people today look at the
old information on CS4 and still think this
is the best Cordyceps for their use. This is
just simply false.
In 1972, when CS4 was isolated there was
no such thing as DNA analysis. So it was not
realized at that time CS4 contained only a
part of the Cordyceps genome. CS4 is cer-
tainly closely related to Cordyceps sinensis,
but it is not Cordyceps sinensis. (CS4 is a re-
lated species, named in Latin Paeciliomyces
hepialis chen). This variation from Cordy-
ceps sinensis is due to a unique feature of
Cordyceps called “Part Spore reproduction”
This is a pretty complex subject, but anyone
wishing a more detailed explanation of this
phenomenon is encouraged to email our
research department and we will be glad
to give you the entire report detailing how
Cordyceps reproduces and why it is so dif-
ficult to cultivate True Cordyceps. The email
address to receive that report is research@
alohamedicinals.com.
Which brings us up to today: Aloha Me-
dicinals set out to cultivate the most po-
tent Cordyceps back in 1999. We started with
the purchase of CS4 cultures from private
manufacturers in China. Then in 2001, we
purchased 10 other Cordyceps cultures from
the Government of China. Since then we
have isolated over 400 different Cordyceps
cultures from specimens purchased in herb
stores and sent to us from China, Tibet and
Nepal. We tried every possible combina-
tion of culture techniques and growth me-
Bringing the latest of 21st century American biotechnology techniques
to this field has resulted in a quantum leap in Cordyceps cultivation,
reducing the cost and increasing the quality of cultivated Cordyceps.
dium, but we realized that by using these
part-spore cultures there were no way to
gain the full potential which is known to
occur in wild Cordyceps. To achieve the wild
Cordyceps quality requires a much more
complex approach, involving replicating the
wild Cordyceps growth conditions and trig-
gering fusion between several part-spore
cultures to achieve the full Cordyceps DNA
genome. This is not to be confused with
Genetic Modification. There are absolutely
NO genetically modified organisms (GMO)
in any Aloha Medicinals product. We are
opposed to the GMO approach, as well as
this being forbidden under USDA Certified
Organic standards. All Aloha Medicinals prod-
ucts are 100% natural, and as close to nature
as we can make them.
In an effort to develop part-spore cultures
into whole Cordyceps, we developed a meth-
od of hybridization for mushrooms which is
so revolutionary in concept it was granted a
U.S. patent. This is a technique which allows
us to mate different part spore cultures, each
of which contain only a fraction of the total
Cordyceps DNA sequence, and ultimately
build the entire sequence into one organ-
ism. This organism is True Cordyceps sinen-
sis, not some Frankenstein monster created
through laboratory techniques, but the real
thing. This is the only cultivated Cordyceps
that is genetically Bio-Identical to the wild
Cordyceps occurring in Nature.
But even once we developed these bio-
identical cultures, which were 100% Cordy-
ceps sinensis in every way, there was still
a problem: The Cordyceps being grown in
cultivation was still not as potent as the wild
collected Cordyceps. To try and resolve this
problem, Aloha Medicinals scientists under-
took an expedition into the heartland of wild
Cordyceps habitat, Tibet. In May and June of
2006 Aloha Medicinals conducted one of the
most comprehensive scientific research expe-
ditions ever undertaken in the mountains of
Tibet to study the natural growth parameters
of wild Cordyceps. Working with the local
nomad people, we identified several hundred
Cordyceps specimens growing directly from
the ground, and carefully measured all the
growth conditions there, such as pH, soil and
air temperature, moisture content in the air
and soil, the other micro-organisms found
in the area, air pressure, virtually everything
that we could measure, we did.
We brought this information back to the
lab, and developed entirely new methods of
cultivation for Cordyceps, which has resulted
in the cultivation of Cordyceps that is not
only bio-identical genetically, but also bio-
identical in it’s analytical signature. Bringing
the latest of 21st century American biotech-
nology techniques to this field has resulted
in a quantum leap in Cordyceps cultivation,
reducing the cost and increasing the quality
of cultivated Cordyceps. These cultivation
methods involved building special growing
chambers where the oxygen is held at 50%
of the usual atmospheric oxygen, and the
temperature is held at just above freezing.
This exactly replicates the conditions found
during the growing season in Nepal and Tibet
at 18,000 feet (5400 meters) elevation. This
low temperature hypoxia growth is also pro-
tected by patents, and Aloha Medicinals is
the only company in the world that grows
Cordyceps using these techniques.
Aloha Medicinals Drug Research Division is currently examining a
newly discovered class of antiviral compounds isolated from these
recently identified Cordyceps strains.

In the course of developing these new the best Cordyceps available today. Why risk
strains of Cordyceps, we have made some your health or your company’s reputation by
fantastic discoveries: Aloha Medicinals Drug using inferior Cordyceps substitutes when
Research Division is currently examining Aloha Medicinals Tru-Cordyceps™ is now
a newly discovered class of antiviral com- available?
pounds isolated from these recently iden- Aloha Medicinals is proud to announce
tified Cordyceps strains. The goal of this the opening of our new manufacturing fa-
research is to produce a new generation of cility in Carson City, Nevada, USA. We are
effective, non-toxic antiviral medications for
now the world’s largest Cordyceps cultiva-
use in treating viral infections including HIV
tor, with a monthly production in excess
and Hepatitis. We also have more than 700 of 175,000 kilograms. Aloha Medicinals is
other species of Cordyceps in our research manufacturing more than one-half the total
department, from all corners of the globe. Cordyceps consumed in the world today!
Most of these have not yet been identified There is a reason for that: Aloha Medicinals
by science, and we are making new discover- is the most potent Cordyceps ever available,
ies regarding their medicinal potential daily.
the only commercially available cultivated
This pioneering work in the field of Cordy- True Cordyceps with a DNA profile exactly
ceps is changing the way medicine will be matching that of wild Cordyceps! Both the
practiced in the future. quality and the quantity capability make the
choice easy. Aloha Medicinals Cordyceps is
Aloha Medicinals Cordyceps is 100% pro- available from stock in any quantity you
duced in America, only in FDA-certified man- require, either for your own use or in bulk
ufacturing facilities and is 100% Certified for formulation into your product!
Organic under USDA regulations. It is simply www.alohamedicinals.com/cordyceps.html