PHINMA UNIVERSITY OF ILOILO

COLLEGE OF ALLIED HEALTH SCIENCES

Nursing Department

DRUG STUDY
Drug Name Classification/ Indications Contraindications Side effects/ Adverse Nursing responsibilities
Mechanism of Action Effects
Generic Name:
 Blocks viral entry into  Combined with  Contraindicated in  CNS:anxiety,
Maraviroc cells by binding to CYP3A4 inhibitors, patients dizziness,  Effectiveness hasn’t
chemokine receptor including protease hypertensive to parasthesia, sensory been established in
type 5 co-receptor patients with dual,
Brand Name: inhibitors (except drug or its abnormalities,
and preventing the mixed, or CXCR4-
initiation of HIV tipranavir and components Peripheral
replication cycle ritronavir), to treat  Contraindicated in neuropathy,sleep tropic HIV-1 infection
Celsentri CCR5-tropic HIV-1 disturbances,  Monitor patient closely
patients with
infection with severe renal depressive for signs and
CLASSIFICATION evidence of viral impairment or disorders,pyrexia, symptoms of infection
replication or HIV- ESRD ( CrCl of pain,disturbances in and hepatic and renal
Antiretrovirals 1 strains resistant less than 30 consciousness impairment
to multiple Ml/minute) who are  Monitor patient for
Route: antiretrovirals talking potent  CV:unstable malignancy with long-
P.O  Combined with CYP3A inhibitors or angina,acute cardiac term use
CYP3A inducers, inducers failure,CAD,
Dosage including  Use cautiously in endocarditis,MI,
Tablet efavirenz, without patients with myocardial ischemia,
25mg strong CYP3A preexisting liver vascular
150mg inhibitors, to treat dysfunction or hypertensive
CCR5- tropic patients who are disorders, edema
300 mg
HIV-1 infection infected with HBV
or HCV  EENT: conjunctivitis,
Frequency:  Because of drug’s ocular infections,
BID mechanism of otitis media, nasal
action, risk for congestion,
malignancy could paranasal sinus
increase disorders,sinusitis,
rhinitis,esophageal,
candidiasis

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