Oncology 13.

Desired response to cancer treatment if the goal is

Dr. Ferrolino TO CONTROL
Sec.A_PRELIMS A. Complete response
B. Stable
1. Changes observed in Ca except : C. Partial
A. Mutation D. Progressive
B. Dysplasia
C. Uncontrolled proliferation 14. Not a warning sign of cancer
D. Invasion & Metastasis A. Ingestion or dysphagia
B. Anemia due to bleeding
2. XXX C. Change in bladder habits
3. XXX D. Weight loss of 10% in 6months

4. Implicated for cervical cancer: 15. XXX

A. Human herpes virus 8 16. XXX
B. Human papilloma virus
C. Ebstein var virus 17. This cancer upon screening detects early disease
D. Hepatitis b virus except:
A. Breast
5. XXX B. Pancreatic
6. XXX C. Colon
7. XXX D. Cervical

8. Systemic forms of ca tx except : 18. Radiotherapy of the tumor or near the tumor site..
Answer: brachytherapy A. linear accelerator
B. brachytherapy
9. Chemotherapy given AFTER locoregional therapy to C. external beam therapy
prolong survival D. teletherapy
A. Primary tx
B. Adjuvant 19. XXX
C. Neoadjuvant
D.palliative 20. Level of prevention which involves clinical treatment
of cancer
10. decrease in tumor size by 15% A. Primary
A. complete B. Secondary
B. stable C. Tertiary
C. partial D. Quarternary
D. progressive
21. What has the worst prognosis?
11. this is the desired response to cancer treatment if A. Grade 1
the goal is to cure: B. Grade 2
A. COMPLETE RESPONSE C. Grade 3
B. stable response D. Grade 4
C. partial response
D. progressive response 22. XXX
23. XXX
12. XXX 24. XXX
25. XXX

JacquesDemolay2017
26. The most accurate staging of cancer:
A. Clinical staging
B. clin staging with tumor markers
C. Surgical-pathological staging
D. Immunohistochemical stain

27. What is the most common paraneoplastic

syndrome?
A. Siadh
B. Hypercalcemia
C. Myasthenia gravis
D. Svc syndrome

28. What is the most important management for SVC

due to lymphoma
A. RT
B. SVC stent
C. chemotherapy

29. Most common site of spinal cord compression.

A. Lumbar
B. Sacral
C. Thoracic
D. Cervical

30. Oncologic emergencies arising from the effect of the

tx
A. Hypercalcemia
B. SIADH
C. Intestinal obstruction
D. TLS

JacquesDemolay2017
Oncology 14. Warning signs of cancer except:
Dr. Ferrolino a. Indigestion or dysphagia
Sec.B_PRELIMS B. Anemia 2 to bleeding
C. Change in bladder habits
1. All are characteristics of cancer, except D. wt loss. 15.
A. mutation
B. Dysplasia 15. Tumor marker in the response of treatment in
C. Uncontrolled Proliferation colorectal cancer:
D. Invasion and metastasis A. CEA
B. C9-19
2. XXX C.
3. XXX
4. XXX 16. The following tumor markers can be used to
5. XXX diagnose certain cancer.
A. CEA – colorectal
6. All are strategies for secondary cancer prevention B. BHCG & AFP - testicular
except. C. CA 19-9 - breast
A. paps smear D. AOTA
B. mammography
C. hepa vacc 17. The FF. are cancers where screening detects early
D. digital exam disease, except:
A. Breast Ca.
7. Desired response to ca tx of goal is to palliate. B. Pancreatic Ca.
A. Complete C. Colon Ca.
B. stable D. Cervical Ca.
C. Partial
D. Progressive 18. Radiation delivered to sealed radioactive material
inserted near or at tumor site.
8. XXX A. Linear acceleration
9. XXX B. brachytherapy
10. XXX C. External beam therapy
D. Teletherapy
11. The desired response to cancer treatment if the goal
is to cure: 19. level of cancer prevention which involved screening
A. complete response test to detect subclinical cancer:
B. progressive disease A. primary prevention
C. partial response. B. secondary prevention
D. stable disease C tertiary prevention
D. quarternary prevention
12. Colorectal CA recommended tests except
A. DRE 20. XXX
B. fecal occult blood test
C. serum cea 21. Cancer with the worst prognosis
D. A. Stage1
B. Stage2
13. Desired response to cancer tx if the goal is to C. Stage3
control: D. Stage4
A. Complete response
B. Stable response
C. Partial response
D. Progressive dse

JacquesDemolay2017
22. What is NOT associated in the surgical-pathological # Response to cancer treatment where there increase
staging in cancer? of tumor diameter by at least 25%:
A. tumor characteristics A.complete response
B. nodal invovlement B. Progressive response
C. patient's functional status C. partial response
D. absence or presence of metastasis D. Stable response

23. XXX # Most common PNS

A. SIADH
24. Malignancy of connective tissue B. Hypercalcemia
A. Squamous cell ca C. MG
B. Adenoca D. SVC syndrome
C. Transitional
D. Sarcoma # Cancer grade with worst prognosis
A.stage 1
25. Gold standard in cancer diagnosis B.stage 2
A. Complete history and pe C.Stage 3
B. Tissue biopsy D.Stage 4
C. Ctscan and mri
D. Tumor markers

26. XXX

27. Most common paraneoplastic syndrome

A. SIADH
B. Hypercalcemia
D. Svc syndrome

28. Most important modality for SVC syndrome due to

lymphoma
A. RT
B. SVC stent
C. Chemotherapy
D. Steroids

29. Most common site of Spinal Cord Compression

A. Cervical
B. Thoracic
C. Lumbar
D. Sacral

30. XXX

# Which of the ff are warning signs of CA? except

A.indigestion and dysphagia
B.anemia 2ndry to bleeding
C.changes in bladder habit
D.wt loss >6mths

JacquesDemolay2017
Oncology 8. TRUE of screening:
Dr. Lim A. Biennial screening and CBE decreases the
Sec.C_PRELIMS risk for breast cancer and start mammography
at 55y/o
1. XXX B. No study have shown that CBE decreases
mortality
2. Cancer of epithelial cells in origin C. Women with BRCA1 and 2 have high risk
A. Sarcoma for breast cancer and recommended with early
B. Carcinoma mammography for screening
C. Lymphoid D. Women at 54y/o with all normal screening
D. Leukemia for 5 years can choose to stop screening

3. Loss of normal apoptosis pathway in 9. True of chemoprevention

malignancy is due to: A. Tamoxifen is not ideal.....causes
A. Loss of BRCA 1 endometrial cancer
B. Increase expression of IL-8 B. Bivalent HPV vaccine offers complete
C. Increase of bcl 2 family member protection against hpv 6, 11, 18
D. Downregulation of spindle checkpoint C. Finasteride.... reduction of incidence of
prostate cancer
4. XXX D. In colon cancer, NSAIDs did not prevent
adenomatous polyps nor causes regression
5. At which level is the cancer growth sorry ang haba kc ng choices.. haha
detectable?
B. 10^9th 10. XXX
11. XXX
6. Which of the following is true regarding CA
A. Fiber intake has an effect(?) on CA 12. Tumor poorly progressive in advanced
B. Risk for CA increases as BMI increases to stages to chemo
>20 kg/m2 a. Pancreatic Carcinoma
C. Fruit consumption reduces(?) CA incidence
D. Melanoma risk = numerous Benign 13. XXX
Melanocytic Nevi
14. Tumor decrease 20% from the baseline.
7. True of chemoprevention A. Partial
A. Tx with cis retinoic acid causes regression B. Complete
of oral leukoplakia C. Stable
B. Lung CA decreases with increase carotene D. Progressive
diet
C. Tocopherol has no effect on the lung CA 15. Most significant risk factor of cancer as a
mortality whole..
D. Diet high in Calcium decreases colon CA Answer: age
risk
16. Most commonly affected by chemo
A. Heart
B. Bone
C. Bone marrow
D. Muscle

17. Mortality in male 20-29 yrs old

Answer: c. leukemia other options: lung,
lymphoma, prostate

JacquesDemolay2017
18. Tumor marker of breast Ca 27. Male Px rushed to ER due to DOB. 1 day
A. 125 PTA, px had session of chemotx. Presented
B. 19-9 s/sx- Facial swelling
C. 15-3 A. Hypersensitivity Reaction
B. SVS sx
19. High mortality in female? C. Pneumothorax
A. Prostate Ca D. Pneumomediastinum
B. Lung Ca
C. Breast Ca 28. (follow up question from the case of SVC)
D. Leukemia >90% of this case is caused by:
A. Thyroid
20. ECOG limit B. Head and neck CA
A. Ecog 2 C. Hematologic
B. Ecog 3 D. Breast Ca
C. Ecog 4
D. Ecog 5 29. Based on patient's primary diagnosis,
what is the best imaging technique on this
21. Oxiplatin has toxicity condition? (ff. up question po eto from the
A. Nuetropenia diagnosis na SVC)
B. A. PET SCAN
C. Nuerotoxicity B. MRI
D. C. CT scan
D. Chest X-ray
22. Docetaxel is specific for cell cycle Answer: C
phase...
A. S phase 30. Most appropriate treatment for SVC
B. G1 phase A. Chemotherapy
C. M phase B. Ct thoracostomy
D. G2 phase C. Antibiotic

23. XXX

24. Antitumor antibiotic

A. Topotecan
B. Temozolomide
C. Altretamine
D. Adriamycin

25. Doxurubicin's cumulative dose for chronic

cardiotoxicity.
A. 450
B. 500
C. 550
D. 600

26. Most common paraneoplastic syndrome..

A. hypercalcemia
B. hypokalemia
C. hyperurecimia
D. hypernatremia

JacquesDemolay2017
Oncology 10. True about SCLC (small cell lung ca)
Dr. Lim A. Commonly present as localized at diagnosis
Sec.A_MIDTERMS B. Commonly present as curable with surgery
C. Extensive disease responsive to etoposide and
1. True about luminal A cisplatin/carboplatin
A. Low response to chemotherapy D. PCI contraindicated to localized SCLC
B. Poor prognosis
C. High grade 11. Predictor of poor outcome for colorectal cancer
D. ER PR HER2 A. No lymph nodes samples during resection
B. Well differentiated histology
2. Most powerful prognostic factor in Breast Ca? C. Perforation
Answer: Lymph node met D. Tumor size

3. XXX 12. A 64 year old Female experienced hematochezia

and weight loss. Colonoscopy revealed sigmoid mass
4. breast histopath assoc with bilaterality which on biopsy showed well differentiated
A. invasive ductal ca adenocarcinoma. Patient underwent colonic mass
B. invasive lobular ca resection and showed 16 LN positive however chest
C. DCIS scan and liver scan were negative for metastasis. What
D. LCIS is the stage?
A. Stage I
5. which of the ff has the best outcome and prognosis ? B. Stage II
A. ER (+) PR (-) C. Stage III
B. ER (-) PR (+) D. Stage IV
C. ER (-) PR (-)
D. ER (+) PR (+) 13. Treatment of choice after surgery
A. Observe
6. Treatment of choice for dcis B. Post operative RT
A. C. Chemotherapy
B. Lumpectomy D. Chemotherapy combined with targeted therapy
C. Mastectomy
D. 14. a 28 y/o male underwent colonoscopy because of
changed in bowel movement with right side mass was
7. True of Non Small Cell Ca noted & on biopsy signet ring histopathology was
A. Squamous Cell Ca at peripheral location found. He further underwent resection with negative 4
B. Adenocarcinoma is associated with smoking lymph nodes. CEA levels however were elevated. What
C. Squamous Cell Ca is responsive to Erlotinib will you suggest?
D. Squamous Cell is Central Location A. no other treatment
B. adjuvant RT
8. best method for dx a suspected lung CA C. adjuvant chemo: FOLFOX
A. transbroncial FNA D. adjuvant chemo plus targeted therapy
B. CXR
C. transthoracic FNA 15. True of Colorectal Ca.
D. sputum cytology A. 10 Lymph node is needed for better diagnosis
B. Screening should start at age 40
9. true of lung ca C. Prognosis is influenced by_______?
A. Common presenting sign is wt loss D. Prognosis is determined by presence of
B. Ct scan screening will reduce mortality rate lymphosaccular invasion.
C. Ct scan is used to check for brain mets
D. Responsiveness for refi....

JacquesDemolay2017
16. Most common side effect of Irinotecan 25. 45 y/o male with liver mass, positive Hep B
A. Hypertension infection. CT revealed 1.5 left hepatic lobe, no vascular
B. Diarrhea involvement negative metastasis. Stage I. Best tx:
C. Rashes A. Radiofrequency/RFA
D. Neuropathy B. Nexavar/Sorafenib
C. Doxorubicin Chemotherapy
17. Backbone tx/therapy of colon CA: D. Chemo RT
A. 5 FU
B. Oxaliplatin 26. XXX
C.
D. Folinic acid/leucovorin 27. Diagnostic for early pancreatic Ca
A. EUS
18. Risk factor for gastric cancer B. dual phase spiral ct scan
A. H. pylori C. PET
B. Blood type O D. MRI
C. Chronic alcoholism
D. celiac sprue 28 .Patient with small adenocarcinoma in the pancreatic
BODY AND TAIL with no lymph node and mets... what
19. XXX procedure?
A. Whipple's followed by chemotx
20. Diffuse type of gastric cancer B. Distal pancreatectomy followed by chemotx
Answer: Linitis plastica C. Gemcitabine + ...
D. Gemcitabine + tarceva
21. What is the risk factor for esophageal cancer?
A. Pernicious anemia 29. 69yo female 3cm adenocarcinoma in the head of
B. H. Pylori infxn the pancreas
C. Nitrates A. Whipple surgery
D. Menetrier's dse B. Gemcitabine +whipple+gemcitabine
C.gemcitabine+rt
22. Initial manifestation of esophageal cancer patient D.gemcitabine+erlotinib
A. Weight loss
B. Dysphagia 30. A daughter of a 80 y/o male visited your clinic to
C. Regurgitation seek for consult about his father who is bedridden
D. tracheoesophageal fistula diagnosed of pancreatic cancer, what procedure of
choice will you advise?
23. True of esophageal cancer A. Best supportive care + erlotinib
A. MC site is lower third B. Gemcitabine + best supportive care
B. Incidence of adenoca decreased over the past 30yrs C. Erlotinib+ Gemcitabine
C. Prevalence in high socioeconomic status D. Capecitabine Xeloda
D. MC in ages 40-50

24. True for hepatocellular ca

A. Jaundice is the presenting sign
B. CA19-9 tumor marker
C. Incidence is higher than deaths
D. Hemochromatosis is a risk factor

JacquesDemolay2017
Oncology 10. True of SCLC
Dr. Lim A. less than NSCLC
Sec.B_MIDTERMS B. ?
C. sole extrapulmonary
1. Characteristic of Luminal A breast CA D. most are peripheral
A. least resistance to chemo e. aota
B. poor prognosis 11. Predictor of porr outcome in colon ca
C. ER PR HER2 negative A.
D. High grade B. LN
C. Perforation
2. XXX D. size

3. Recommended in breast cancer surveillance 12. XXX

A. Bone scan
B. Pelvic exam 13. Treatment of choice case 12-13:
C. Blood exam A.Observ
D. Chest x-ray B.Post op RT
C.Chemo
4. Breast cancer histology with propensity for bilaterally D.Chemo with targeted therapy
A. Invasive ductal CA
B. DCIS 14. XXX
C. Invasive lobular CA
D. LCIS 15. CRC bad prognosis
A. 10 lymphnodes
5. Hormone receptor result with the best outcome and C. Penetration
prognosis
A. er-, pr – 16. MC side effects of Irinotecan?
b. er-,pr+ A. hypertension
c. er+, pr – B. Diarrhea
D. Er+, pr + C. Rashes
D. Neuropathy
6. XXX
17. Backbone drug treatment of colorectal cancer
7. True of NSCLC A. 5 FU
A. squamous occur peripheral lung B. oxaplatin
B. adenocarcinoma associated with smoking C. Irinotecan
C. squamous histologically favorable to erlotinib D. Folinic acid
D. SCLC central in location
18. XXX
8. Best method for diagnosing a suspected lung cancer
A. VATS 19. XXX
B. Transbronchial FNA
C. sputum cytology 20. Diffuse type of gastric CA
D. Transtracheal FNA A. linitis plastica
B. seen in older patients
9. XXX C. common in antrum
D. frequently ulcerative

JacquesDemolay2017
21. Etiologic factors associated with esophageal cancer 30. 80y/o male patient with stage 4 pancreatic ca
A. Pernicious anemia consulted for advice to what treatment he can have
B. H. Pylori gemcitabine+BSC
C. Nitrate
D. Menitiers # 55 y/o, abdominal pain with anemia, 1.5cm mass on
endoscopy, adenocarcinoma, ct scan no mets
22. Initial symptoms in majority if esophageal cancer A. total gastrectomy
patient B. total gastrectomy plus chemo
A. Weight loss C. total gastrectomy plus LN disection
B. Dysphagia D. total gastrectomy plus LN disection plus chemo
C. Regurgitation
D. Transesophageal fistula

23. XXX

24. XXX

25. 45 years old found with liver mass and positive for
hepB infection. CT Scan revealed 1.5 cm hepatic lobe
mass with no vascular involvement and (-) metastasis.
Patient stage I liver cancer
A. RFA
B. sorafenib
C. Doxorubicin chemo
D. chemoRT

26. XXX

27. Imaging modality of choice for early pancreatic CA

contemplating surgery?
A. EUS
B. Dual phase CT scan
C. PET
D. MRI

28. Patient presented with small adenocarcinoma at the

pacreatic body and tail, no metastasis to the LN and
other organs. TX:
A. Whipple +RT
B. Distal Pancreactomy
C. Gem+RT
D. Gem

29. 69 y/o, female, pancreatic adenoma, 3 cm, head of

the pancreas, mets to Liver, what treatment?
A. Whipples + Chemo
B. Chemo + Whipples + chemo
C. Gemcitabine + RT
D. Gemcitabine + Erlotinib

JacquesDemolay2017
Oncology 9. The following are true regarding treatment of small
Dr. Ferrolino cell cancer except:
Sec.C_MIDTERMS A. concurrent chemo-radiation is the treatment of
choice
1. All are risk factor of breast cancer EXCEPT B. the cornerstone of therapy for extensive disease is
Answer: early pregnancy chemotherapy without thoracic irradiation
C. prophylactic cranial irradiation is recommended for
2. XXX all with small cell CA
D. long term survivors of SCC are high risk for SCC
3. XXX developing 2nd malignancy

4. Recommended for operable breast cancer EXCEPT 10. Risk factor for Colorectal Cancer EXCEPT
A. Annual breast mammogram A. Tobacco
B. Monthly BSE B. High fiber low fat animal
C. Check apc 3-6months for 3 years C. Inflammatory bowel disease
D. Pelvic exam papsmear every 3 years D. Age >50

4. True of breast cancer management: 11. XXX

A. Postmastectomy is the treatment recommended for
big tumors only 12. True of Colorectal Cancer EXCEPT
B. Neoadjuvant Therapy is the treatment for local A. Majority is adenocarcinoma
advanced and inflam. Breast cancer. B. Left sided tumor is annular in growth and therefore
C. Hormonal Therapy seldom cause obstruction
D. Management for ductal in situ is MRM and RT C. Proximal colon is more common
D. Endoscopy with biopsy is the....
5. XXX
13. Favorable prognosis of CRC
6. The following indicates poor prognosis for Lung A.
Cancer, EXCEPT B. Well differentiated (answer)
A. Weight Loss >10% in 6 months C. Serosal penetration
B. Generalized weakness & fatigue D.
C. Large Cell Histology
D. Female 14. XXX

7. True about the management of NSCLC except: 15. Etiology of Hepatocellular Cancer:
A. Radiation is an alternative for medically unfit patients A. Chronic Hepatitis B
B. Surgical resection remains the TOC if cure is the goal B. Wilson
C. Sequential CR increases toxicity but has better local C. EBV
control compared to concurrent CR D. Aflatoxin
D. Best supportive care is an option for advanced and
metastatic disease 16. Patient underwent abdominoperineal resection for
stage 2 rectal cancer. What is your next step?
8. True of Small Cell Cancer: A. Adjuvant chemotherapy
A. Less aggressive than NSCA B. Adjuvant chemo-radiotherapy
B. Chemo resistant but radio sensitive C. Adjuvant radiotherapy
C. 4 percent may solely have extra pulmonary D. No further step
manifestation
D. Occurs Mostly in the periphery

JacquesDemolay2017
17. The most specific laboratory finding for the 29. Patient diagnosed with Colon Cancer, Stage 2,
diagnosis of Hepatocellular Cancer underwent hemicolectomy. What is your next
A. Elevated AST treatment?
B. Elevated alpha‐feto protein A. Adjuvant Chemotherapy alone
C. Elevated bilirubin B. Adjuvant Chemotherapy and Radiation
D. Deranged prothrombin time C. Adjuvant Radiation Therapy
D. No further treatment
18. XXX
19. XXX 30. What is the best adjuvant therapy for
premenopausal (lymph node +, ER/PR +)
20. 60 years old, post menopausal, diagnosed with A. Chemotherapy
breast cancer, with bone metastasis only. Benefit best B. Hormonal Therapy
w pain control and C. Chemotherapy + Hormonal Therapy
A. Hormonal Therapy D. Radiation Therapy
B. Systemic Chemotherapy
C. Surgery + RT
D. NOTA

21. A 45 year old, male, with father and sibling who died
of colon cancer. What screening test will you prefer for
the other family members of the patient
A. Screening test every 3-5 years starting at age 50
B. Every 3-5 years screening regardless of age
C. Annual screening as early as 20's
D. ...

22. A risk factor for Esophageal Cancer.

Answer: B. Caustic ingestion

23. XXX
24. XXX
25. XXX
26. XXX

27. All are risk factors for Gastric Cancer EXCEPT

A. Tylorins (answer)
B. Menetiers
C. H. Pylori
D. Nitrosamine

28. A 50 yr old, man, presents recurrent epigastric pain

associated with weight loss for 2 months. Upon physical
examination, left supraclavicular lymph node was
noted. What is the goal of treatment?
A. Cure
B. Disease control
C. Palliative
D. All of the above

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