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morlock@tuhh.de
040 42878 3253
Denickestrasse 15 Rm 3514
0. Overview
Prerequisites: none
Course format, period: 2 ECTS lectures, 1 ECTS exercise,
2 ECTS PBL , winter term
Work load: 6 ECTS Language: English
Performance evaluation: The examination consists of
- Final Exam (70%, 90 Minutes)
- Homework (10% extra credit for exam): given during
exercises, has to be turned in through stud_ip by Tuesday
the following week before noon
- Problem Based Learning (30%): presentation + evaluation
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 2
PBL
Applied Statistics
Problem Based Learning (PBL)
Contact:
Philipp Messer
philipp.messer@tuhh.de
Adrian Falkenberg
Institute of Biomechanics adrian.falkenberg@tuhh.de
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 3
PBL
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 4
PBL
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 5
Timetable
Schedule Lecture:
Oct. 16th Lecture 1 15:00-16:30 (H0.16)
Oct. 16th Sign into Exercise & PBL groups 20:00 (in groups @ 4 members, Ai, Bi, Ci via StudIP PBL)
Schedule Exercise:
Oct. 23rd Group A 13:00-13:45 (L3038P1)
Oct. 23rd Group B 13:45-14:30 (L3038P1)
Oct. 24th Group C 13:15-14:00 (L3038P1)
….. and so on…
Exception: no Exercise on Oct. 31st
Oct. 30th Group A & C/2 13:00-13:45 (L3038P1)
Oct. 30th Group B & C/2 13:45-14:30 (L3038P1)
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 6
Timetable Seminar
Date Task
01.11.2018 Seminar Group A Descriptive Statistics
08.11.2018 Seminar Group B Descriptive Statistics
15.11.2018 Seminar Group C Descriptive Statistics
22.11.2018 Seminar Group A Correlation
29.11.2018 Seminar Group B Correlation
06.12.2018 Seminar Group C Correlation
13.12.2018 Seminar Group A Categorical Data
20.12.2018 Seminar Group B Categorical Data
10.01.2018 Seminar Group C Categorical Data
17.01.2018 Seminar Group A Statistics Guidance
24.01.2018 Seminar Group B Statistics Guidance
31.02.2018 Seminar Group C Statistics Guidance
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 7
Seminars
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 8
Individual PBL
Grading
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 10
Grading (continued)
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 11
Grouping
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 12
Task 1 – Descriptive Statistics
Acquiring and presenting data:
TUHH Mensa
Abendblatt.de
Important
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 14
Exercise Applied Statistics WS17/18
Contact:
Valerie Polster (valerie.polster@tuhh.de)
Sebastian Zobel (sebastian.zobel@tuhh.de)
Location & Time:
DE17 – L, Room 3038 P1
Group A: Tue 13:00-13:45 (start 23.10.2018)
Group B: Tue 13:45-14:30 (start 23.10.2018)
Group C: Wed 13:15-14:00 (start 24.10.2018)
Homework:
optional 10% bonus points
StudIP: 1 week online (Tue 17:00–Tue 12:00)
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 16/17 Lecture 1 Slide 15
Timetable
Schedule Lecture:
Oct. 16th Lecture 1 15:00-16:30 (H0.16)
Oct. 16th Sign into Exercise & PBL groups 20:00 (in groups @ 4 members, Ai, Bi, Ci via StudIP PBL)
Schedule Exercise:
Oct. 23rd Group A 13:00-13:45 (L3038P1)
Oct. 23rd Group B 13:45-14:30 (L3038P1)
Oct. 24th Group C 13:15-14:00 (L3038P1)
….. and so on…
Exception: no Exercise on Oct. 31st
Oct. 30th Group A & C/2 13:00-13:45 (L3038P1)
Oct. 30th Group B & C/2 13:45-14:30 (L3038P1)
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 16
0. Overview
Reading resources:
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 17
Housekeeping
• Scripts and informations through stud_ip
• You have to register
• Script available evening prior to the lecture
• Homework through stud_ip
• Questions for Homework: After each lecture (17:00)
• 1st homework (pulldown „VIP“) will be online
October 30rd on stud_ip
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 18
0. Overview
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 19
Housekeeping
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 20
0. Overview
Objectives: Introduction to basic statistical methods and
their application to simple problems using
established software (SPSS).
Contents: • Introduction, Definitions, Variables, Basics
Descriptive Statistics
Distributions
Chi square test
Simple regression and correlation
Multiple regression and correlation
Analysis of Variance
Survival Analysis
Discriminant analysis
Analysis of categorial data
Non-parametric statistics
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 21
0. Overview
Do we need statistics?
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 22
0. Overview
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 23
0. Overview
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 24
0. Overview
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 25
0. Overview
State elections 14.10.2018 Bavaria
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 26
0. Overview
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 27
1985
http://www.cdc.gov/nccdphp/dnpa/obesity/trend
Source: BRFSS, CDC.
Source: Mokdad A H, et al. JAMA 1999;282:16.
No Data <10% 10%–14% Source: Mokdad A H, et al. JAMA 2001;286:10.
Source: Mokdad A H, et al. JAMA 2003;289:1.
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 28
Obesity Trends* Among U.S. Adults
2011
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 29
0. Overview
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 30
Obesity Trends* Among U.S. Adults
BRFSS, 2011
*Prevalence reflects BRFSS methodological changes in 2011, and these
estimates should not be compared to previous years.
2011
*Sample size <50 or the relative standard error (dividing the SE by the prevalence) ≥ 30%.
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 31
*Sample size <50 or the relative standard error (dividing the SE by the prevalence) ≥ 30%.
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 32
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 33
0. Overview
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 34
1. Introduction
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 35
0. Overview
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 36
1. Introduction
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 37
1. Introduction
Reliability
Objectivity
Validity
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 38
1. Introduction
Population: The set of all units of interest, can be
finite (all students TU) or nearly
infinite (all students).
Sample: The subset of the population
actually observed.
Variable: Attribute of each unit (income, age,
satisfaction). Variable.
Parameter: Numerical value, fixed.
Y = 2a * X
1. Introduction
Steps in Study Design and Implementation
1. Background research and literature review
2. Define the goals and hypotheses of the study
3. Determine variables to be measured
4. Develop a plan to collect the data
Sampling design
Sample size
Inclusions and exclusions
5. Train Personnel
6. Gather Data
7. Analyze Data
8. Report Results
(adopted from Dr. Elizabeth Newton MIT)
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 40
1. Introduction
Steps in Study Design and Implementation
1. Background research and literature review
2. Define the goals and hypotheses of the study
3. Determine variables to be measured
4. Develop a plan to collect the data
Sampling design
Sample size
Inclusions and exclusions
5. Train Personnel
6. Gather Data
7. Analyze Data
8. Report Results
(adopted from Dr. Elizabeth Newton MIT)
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 41
1. Introduction
Steps in Study Design and Implementation
1. Background research and literature review
2. Define the goals and hypotheses of the study
3. Determine variables to be measured
4. Develop a plan to collect the data
Sampling design
Sample size
Inclusions and exclusions
5. Train Personnel
6. Gather Data
7. Analyze Data
8. Report Results
(adopted from Dr. Elizabeth Newton MIT)
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 42
2. Classification of Variables
Nominal
weakest level, different categories
dichotomous or polychotomus
(gender, place of residence)
Ordinal
not only grouping into categories but also ordering
dichotomous or polychotomus
(age <= 39, >= 39; pain: low, medium, high)
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 43
2. Classification of Variables
Independent
variable under investigation re. which is modified
by investigator (treatment, cause)
Dependent
variable used to describe the outcome
Covariate
independent variable affecting outcome of study
but not of intrinsic interest
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 44
1. Introduction
Steps in Study Design and Implementation
1. Background research and literature review
2. Define the goals and hypotheses of the study
3. Determine variables to be measured
4. Develop a plan to collect the data
Sampling design
Sample size
Inclusions and exclusions
5. Train Personnel
6. Gather Data
7. Analyze Data
8. Report Results
(adopted from Dr. Elizabeth Newton MIT)
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 45
1. Introduction
Sampling design
Descriptive:
One group (students of this lecture)
Observational:
Investigator records data without intervening.
Difficult to distinguish effects of predictors and
confounding variables
Comparative:
2 or more groups, e.g. students of 2 different
universities, common final exam.
Experimental:
Investigator actively intervenes to control study
conditions, investigate relationship between
intervention and response (outcome) variables
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 46
1. Introduction
Sampling design
Retrospective (case-control)
look back in time (technique A vs. technique B over
the last 20 years)
Cross-sectional
sample is investigated at a single point in time
(weight of rural and city children)
Prospective
sample is followed forward with time (2 different
medications, follow patients for 10 years)
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 47
1. Introduction
Data are usually organized as a matrix with rows
corresponding to observations and columns
corresponding to variables
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 48
2. Classification of Variables
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 49
3. Basic Statistics
3.1 Descriptive Statistics
Mean
arithmetic mean
Mode
the value that has the largest number of observations, namely the most
frequent value or values.
mode of {1, 2, 2, 2, 3, 9} = 2, the arithmetic mean = 3.16
the mode of {apple, apple, banana, orange, orange, orange, peach}= orange
(WIKIPEDIA)
Median
the value below which 50% of the scores fall, or the middle score
( 1/2 of the population will have values <= median re. >= median );
even sample size: the median is the mean of the two centermost scores
median {1, 2, 2, 2, 3, 9} = 2 (WIKIPEDIA)
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 50
3. Basic Statistics
Variance
measure of dispersion around the mean, equal to the sum of squared
deviations from the mean divided by the number of cases (population mean),
re. by one less than the number of cases (sample mean).
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 51
3. Basic Statistics
Variance
measure of dispersion around the mean, equal to the sum of squared
deviations from the mean divided by the number of cases (population mean),
re. by one less than the number of cases (sample mean).
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 52
3. Basic Statistics
Standard deviation (wikipedia)
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 53
3. Basic Statistics
Range
The difference between the largest and smallest values of a numeric variable;
the maximum minus the minimum.
Minimum
The smallest value of a numeric variable.
Maximum
The largest value of a numeric variable.
© Michael Morlock Institute of Biomechanics TUHH Applied Statistics WiSe 18/19 Lecture 1 Slide 55