Responstbility

-gene€tjon of
ana uplcao:rg MSDS on MSDS of the
irtermedieie &

A( ia,i i5

Definition
TLV: - ]'he thresltold jilnit value (Tt,\, ) ol a chenrical subsLance is a levt:l r()
!.\,hich it is ltr.lievr:rl a rvoTker can bc exposed dav after da), for a .,r,orking
Iifetimc \ rithoui .rdvt.rse hcaith eflccis.

Flash Point:- l he flash p()int ol a volatile material is tie lowest

ten]perature at r^,hjch it c:I] vaporizc to form an ignitable mixturc in airl

Auto-ignition'l'emperature: -'l'h('auto is]]ition temperature ot l<jndline

iloint ol a sub:-i.rnce, is thc lo\,\,est tel')lperature at which it \,vill
spontaneously ignite in a norinal atmospherc without an external souTce ol'
ignition, such as a tlanle or sp.trk

Lower Explosive Limit (LELIr- 'l'i)c 1r)u'est concentt.ati.)n IpI.rcentagc) ot .l

gas oT cr lrapor rn.rir capahlc ol plotlucing a flash of tir.c irj )i1rsor.r(t(,ol ,tIr
ignirion sorrlr t, i,r |c, flamr,, hc;t i

Upper Explosivc Limit (UEL):- Hrghest concentration Ip,rrcentagc) ot i]

gas or a vapol in .rrr capablc rrl producing a flash of fl rt, in prcrence ol an
ignition soulcr {.rr-c, flamc, heat).
,/t,
Ari a,",i!
 8/8/2A-_

Definttion
Boiling Point (BP):- Thu [:oiltng poi]lt ()1 it subst.in(c is the temperature at
which the yapor pressur-c oftht, liquirl cquals tltc ilressure surrounding the
liquid and the liquid changes rntr) ir vapor:

Melting Point (MP):- Thc'rnelt:1)g pornL rif I soljd is the temperature at

\.\,hich it cl]anges^ state iionr solid ro IiqLlid.

Vapor Pressure {VP):- Vapo| pressuri'or equilibrium vapor pressure is dte

pressure exerteel by a vapor in thefmod),namic equilibrium with its
condensed phases (soli(i or iiqu id J al a gjr,on lcllitcratrlrc in a closed
syr tc n'r.

Lethal Doseqo:- LD.u is ti]e a]ltouDt ol a rnarc|ial, girzcn all at once, whiclr
ca uses the death of 50(X, Ionc ha il ) ot a er.ou p of tesr animals. The LDqO js
one \^/ay to measure the short-torm potsoning r)ore'ntial (acute t()xjcity) of a
n r ntcria L

Lethal Concend ationqoi, l,C v,riucs ul(rJlly reiljr to the co)]cenration of il

chenlical in ilir hLlt ill et)\,ir.)l'llrtr.nt:tl \,rLi(iies il {t.l| .tls() ntr-';rn lhc
(Orlcentration ol a Chemir:al in ,"r.-tir:r. t6l
A.tavis

Content of MSDS
,SECTION ldentificatjon rht' sultstalrce/mrxture;lnd ofthe company
^ 1 t,rl /
u ndertakine
SEC'I'ION 2: Co m posi tiorr / i n i( ) r'r)1 iir ti o n o n in grL.d ie n ts
$cTroN 3: Hazard lder tifica tiorl
SECTION 4: First aid n'leasurcs
SECTION 5: Firefighting measu res
SECTION 6: Accidental relsase nreasures
SECTION 7: Handling and storage
S ECTION 8: Exposure contr,rls/Fr.,r \,,nJr l,T{JLr'(:L,)
SECTJO N 9: Physicalancl r:h, !,\ iciil prop(,r'ri.s
S I]CTIO N 1O: Stability and r('il( tivir_\,
SECT]ON ]1: loxic0logical ilrir)rntction
SF]CTIO N ]2: Ec()logicai int()r .t rion
sllCl'toN tii: Dispos:lI considcr;rLrons
SFIC'r't0N 11: 'Trltnsport inl{) r'nlir tron
S IIC'I IO N i5 llegulal{)ry inlrrrntatktll
Sll(ITION i {) Olhrr inlorma I t()n

Aclavis
 Receipt
; No raw tnatcrial rrr.chenric;rl !llrhROHcode
r^hall be r-eceived bv
warehousc lvrthoLt tts nldl.cn.rl ratcn UaU
"iteet.
- Warehouse woul(l scjld ltard (.(]p,v of the
MSDS to the respective
. ryt and gHS dep.rrlrncnt.

. Use,rdepartmer]t shall nrrrntain copy of MSDS with

then and
EH.Sdepartment sha I r lrt,ck tne .rrtetluacy it.ilail;;
upload the 1!ISDS on sent,r. ;irli'"
IfsuFficient data is not available rn IlSDS frori the
suppliel; thetl
MSDS can be referred from the s oiiwafe of reputed
manufactrlrel-s
like Merck, Sigma Aldrich erc. or d.wnloaded iiom
the internet by
referrjng sjtes like qwtlgr](xls,.r
c;Tr:li c
wwu-,_msds.cortI.

N\I
A.lavis

Generation
; For any Rnished product& inrermcdiittes,
R&D r.vill generate MSDS. To
generate the MSDS. (lata Jviiilable t"\,ith
nAO, intorm'ationlr.aiiaUf e
from literature, internet or {)ther. rnirnLrfacturers will
t eut.
crjtical informdtr()n rcqu ir .rl tc-sts wil I be carriea
out ",=io..uO.
taDoratory ..lJ'tt,ces5d r! "i "rl"anrl
- CHS guidelines r,riil br: ibllrrwcrl rvhcr.r,vcr recluired.

G l,)be I Aaho-" i 2'n n-ot SYJJP*-\-

A,ctavis
 c c --

Distributton
MSDS ofall n'tanufacturing raw materials, l-aboratory chemicals,
finished products and intermediates wjli be revje,,vei for adequacy
o1 data and uploaderl on sefver by EHS depr.

A1lempioyees u,ill havt. reacl only access to all uploaded MSDS. Or

they can download thc IVSDS iionr server

EHS Dcpt. rvill chrrk availabjlirl, ot t,1SDS t-irh respe*ive depl

during theiI dcpJ11 iil.ntal s.tfctv inspcctjon.

?,H
Ac lav is

Training

All employees l)an(lljng chentjcal mUsr recejv!, traiojng on MSDS

'l'his tiainjnfl rs llipi.rll_v
-lhc
EI-lS DenJrtrrrr]lrt
L.r\ ( '',{j .:)C. .l(.\ )
cond!lcl.crj on ln annuai basji
\",ill(on(j!cl iliSl)s trainjng. Sullject n.tafter
(, \(,, tt(,ltS ,,1 !iSl):

,tv
Actavis