Predisposing factors: Unknown Etiology Precipitating Factors:

Age: 39 Smoker
Family History of Hypertension Receptionist
Family History of Diabetes Mellitus Abnormal Placentation Takes depo povera
Occasional Alcoholic Drinker
Incomplete Abortion 2014
Inadequate Cytrophoblastic Invasion of Maternal Spiral Arteries

Damage to Endothelial Cells

Increased
Response to Angiotensin II Vasoconstrictor Effects

Decreased Cardiac Output

BP: 160/100 Hypertension Increased Platelet Aggregation

Increased Systemic Vascular Resistance

Initially Thrombocytosis
then Thrombocytopenia
Systemic Vascular Spasm

Increased Fibrin Production

Decreased Circulation to Organs

Formation of Fibrin Meshwork

Gastrointestinal Tract Kidneys Placenta HELLP
Syndrome
Rupture and Hemolysis of RBC
Vasospasm Bleeding in Decidua Basalis
Decreased Gastric
Motility Disseminated Hgb: 109
Decreased Blood Flow Resistance Intravascualar Anemia Hct: 0.31
Hematoma Formation Coagulation WBC: 12
Nausea
Glomerular Damage
Vomiting of Excessive (paradoxical) Pale
Separation of Placenta
Previously bleeding Easy Fatiguability
Ingested Food Increased Release of Renin Decreased Glomerular Decreased Insulin
Permeability of Filtration Rate Abruptio Placenta
Glomerular Decreased Protein Synthesis Death (if untreated)
Angiotensin I
Membrane Partial Separation
Decreased Urine Output
Angiotensin II Increased Glucogenesis Bright red
Protein leak across the Creatinine: Marginal Vaginal Bleeding
Increased Creatinine blood with
capillary membrane and 1.3 mg/dl Hyperglycemia blood clots
into the urine Sodium & Fluid Retention

Grade 2 Bipedal Glucosuria

Edema
Bubbly Urine Proteinuria Edema
Polyuria
Pre-Eclampsia