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PHARMACOLOGY
1. General Pharmacology
Introduction to Pharmacology- Definition, scope and source of drugs, dosage forms and routes
of drug administration. Pharmacodynamics-Mechanism of drug action, Receptors, classification
and drug-receptor interactions, combined effects of drugs, factors modifying drug actions.
Pharmacokinetics-Mechanism and principle of absorption, distribution, metabolism and
excretion of drugs. Principles of basic and clinical pharmacokinetics. Pharmacogenetics.
Adverse drug reactions.
Discovery and development of new drugs-Preclinical and clinical studies.
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Anti-hypertensive drugs, Anti-anginal agents, Anti-arrhythmic drugs.
Drugs used in congestive heart failure. Anti-hyperlipidemic drugs. Drugs
used in the therapy of shock.
Haematinics, anticoagulants and haemostatic agents.
Fibrinolytics and antiplatelet drugs.
Blood and plasma volume expanders.
9. Chemotherapy
General principles of chemotherapy. Sulphonamides and co-trimoxazole.
Antibiotics- Penicillins, cephalosporins, chloramphenicol, Macrolides, quinolones and
fluoroquinolons,. Tetracyclines. Aminoglycosides and miscellaneous antibiotics.
Chemotherapy of tuberculosis, leprosy, fungal diseases, viral diseases, AIDS, protozoal
diseases, worm infections, urinary tract infections and sexually transmitted diseases.
Chemotherapy of malignancy.
12. Chronopharmacology
Definition of rhythm and cycles. Biological clocks and their significance leading to
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chronotherapy.
13. Immnopharmacology
Immunostimulants and immunosuppressants.
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