Name of organism Reservoir Transmission Metabolism Virulence Toxins Clinical Treatment

Bacillus Herbivores Endospores • Aerobic 1 .Unique protein Exotoxin: 3 1 . Cutaneous (95%):(Hide Porter’s 1.Ciprofloxacin
Anthracis (zoonotic) 1.Cutaneous( /Facultative capsule(gamma proteins ds) 2 .Doxycycline
(Gram +,rod A. Sheep abraded anaerobe. D-Glutamic a)PA-helps 3.Raxibacumab (monoclonal
shaped,arranged in B. Goats Skin) acid);antiphagoc Binding painless black vesicles(Malignant antibody for use in inhalational
chains,non-motile.) C. Cattle 2. Inhalation ytic. b)Edema Pustules); anthrax).-Neutralize protective
3 .Ingestion 2 . Non-motile Factor-! Antigen.
3 . Virulence cAMP 4. Vaccine: for high-risk
NON-FASTIDIOUS depends on c)Lethal individuals
(so grow on ordinary acquiring two Factor- A. Vaccine is com posed of the
Media) plasmids.(pXo1 Cleaves 2. Pulmonary (woolsorter's protective antigen ( PA)
and pXo2). MAPK(cause B. Animal vaccine is composed
Death) disease) –fatal if of a live strain, attenuated
untreated,Associated with by loss of its protein capsule.
bioterrorism.

3. G I : abdominal pain,

vomiting and bloody

Diarrhea.

Infection results in

permanent immunity (if

the patient survives)

Pus-malignant pustule, Sputum-pulmonary, CSF-hemorrhagic meningitis

Ascoli’s =sample putrefied Form.(Ring precipitation test).

Nutrient Agar: 2-3 mm, Irregular, round, Greyish white with frosted glass
appearance.Medusa head appearance under low power microscope.

Bamboo stick appearance-non-bulging spores appear hollow.

Frosted Glass appearance.

Name of organism Reservoir Transmission Metabolism Virulence Toxins Clinical Treatment
Bacillus Cereus ----------- spores Aerobic No capsule Enterotoxins Food poisoning: Nausea ,vomiting 1 .Vancomycin
motile 2 types ,diarrhea.
2. Clindamycin
Ocular diseases: keratitis,
Panopthalmitis.
3. Resistant to beta-lactam
Larvicidal agent for mosquito
Bacillus control. antibiotics
Thuringenesis
4. No treatment for food
Cleansing agent(Detergent)
B.Subtilis Amylase(Breakdown startch) poisoning ("Be serious,
Bioremediation(break pollutants)
Help in fermentation Dr. Goofball: food poisoning
Pesticide industry(protect against
fungi) is caused by the pre-formed
Bacillus
Stearothermophilus Autoclave,Plasma sterilizer.
enterotoxin)
B.Atrophaeus Hot air oven,EO sterilizer.
Name of organism Transmiss Metabolis Virulence Toxins Clinical Treatment
ion m
Cornybacterium Diphtheriae Respirator Faculative Pseudomembrame Exotoxin(coded by Respiratory Diphtheria: 1)antitoxin(anti
y droplets Anaerobe forms in the lysogenic Phage) Tonsil,pharynx(faucial)>nose>larynx. diphtheria
Morphology: from a Catalase pharynx which A subunit:block proein serum)---
1.Gram +ve pleomorhic Rod carrier +ve serves as a base to synthesis By blocking DT→→inflammation→necrosis of neutarlize
Corny=club shaped secrete toxin. EF2 epithelium and exudate----leathery toxin.
2.Non-spore Forming B subunit: Provides greyish white pseudomembrames. 2)Antibiotics—
3.Non-motile entry into cardiac and penicillin/eryth
Two characteristics neural tissues. Inner band---fibrin romycin(DOC)
1)chinese letter/cuneiform Outer layer---neutrophils,RBC,bacteria. {if Given early
arranegement ----V/L shaped in Diptheria is toxemia within 6 hrs
smear. not bacteremia. Extension of pseudomembrame----fatal useful—kill
2)Metachromatic granules---at Bac are non- airway obstruction and asphyxia--death. bac}
the ends/poles. invasive,present at --Also to treat
local site and secrete Bull neck appearance: massive tonsillar cutaneous
toxins into swelling and neck edema. diphtheria,carri
bloodstream. Cutaneous Diptheria: Bacteria mediated ers.
not toxin.
3)DPT vaccine
Systemic complications:
Myocarditis: arrhythmias and dialated
cardiomyopathy.
Neurologic: toxin mediated
demyelinating disorder .Invovlve
cranial, peripheral nerves.