VMware vSphere 6.0 vs. vSphere 6.

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This site explains the key differences between vSphere 6.0 and vSphere 6.5. An overview comparison
from all vSphere Versions is available here.
vSphere 6.0 vSphere 6.5
Released March 2015 November 2016
Physical CPUs per host 480 576
Physical RAM per host 12 TB 12 TB
VMs per host 1024 1024
vCPU per VM 128 128
vMEM per VM 4 TB 6 TB
Cluster Size 64 64
High Availability Reactive HA Proactive HA
vSphere Integrated NO YES
Containers
VM Hardware Version 11 13
VMFS Version 5.61 6.81
Management vSphere Web Client vSphere Web Client
vSphere Client (C#) HTML5 Client
Authentication Platform Services Controller Platform Services Controller
Management
vMotion vMotion across vCenters vMotion across vCenters
vMotion across vSwitches vMotion across vSwitches
Cross-Cloud vMotion
vMotion Network Support L3 Network L3 Network
max. 100ms RTT max. 100ms RTT
vMotion Traffic Encryption
Win to vCSA Migration vCenter 5.5 to vCSA 6.0 vCenter 5.5 to vCSA 6.5
vCenter 6.0 to vCSA 6.5
REST API NO YES
VM Encryption NO YES
Virtual Volumes Virtual Volumes 1.0 Virtual Volumes 2.0
Virtual SAN VSAN 6.0 / 6.1 / 6.2 VSAN 6.5
vCenter Type Windows Windows
Linux (vCSA) Linux (vCSA)
vCenter HA NO YES
vCenter Native Backup NO YES
vCSA Scale (vPostgres) 1000 Hosts 2000 Hosts
10000 VMs 25000 VMs
vCSA Operating System SUSE Enterprise 11 Photon OS