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• Embryonic development takes place only outside the body of human host in soil because it requires
low temperature, more oxygen and suitable moisture.
• Inside the shell the zygote develops into rhabditiform larva or first stage juvenile in 10-14 days.
• The larva of first stage is not infective . It rests for a week and completes first moult within egg and
becomes second stage rhabditiform larva which is infective.
• The transmission of infective stage through embryonated egg takes place by contaminated food and
water.
• The embryonated egg passes into the intestine of man and second stage larva hatches out from the
egg.
• In lungs, larva complete its second and third moulting (becomes third and fourth stage
larva). In small intestine it completes fourth or final moulting and becomes fifth stage
of larva.
• Duration of wandering journey from intestine to intestine is about three weeks. Within 8-10 weeks
adult Ascaris starts reproduction.
• Aberrant migration is the migration of ascaris from lungs to brain, spinal cord, eyes, etc.
• Ascaris is pathogenic. It cause the disease, ascariasis. Most pathogenic larva of Ascaris is fourth stage
in larva.
• Main symptoms of ascariasis are – abdominal discomfort, nausea, vomiting, diarrhoea and colic pain.
• Toxin produced by Ascaris may interfere with protein digestion.
• Ascariasis can be treated by antihelminthetic drugs such as oil of Chenopodium, Santonin, Antipar,
Tetrachloroethylene, Alcopar, Decaris, Diethylcarbamazine, etc.
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• Dracunculus medinensis à It is a digenetic endoparasite with man being the primary
host and cyclops as the secondary or intermediate host. It is also called ‘Fiery serpent’. The adult
worms occur in the subcutaneous tissue, especially of arms, shoulders and legs, forming blisters.
Female is very long while male is short. The guinea worm disease has been eradicated from India.
• Loa loa (Eye worm) à It is a filarial roundworm of central and western Africa. The adult
migrates through the subdermal connective tissues of human host. Sometimes they pass across the
eyeball. Local swelling accompanies these migrations. Tabanid flies act as transmitting vectors.
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