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on
“NANOROBOTS IN HUMAN BODY”
Submitted in partial fulfilment of the requirements for the award of
DIPLOMA
in
ELECTRONICS AND COMMUNICATION ENGINEERING
Submitted by
ANANDHU R
Reg. No:17201087
DEPARTMENT OF
ELECTRONICS AND COMMUNICATION ENGINEERING
DEPARTMENT OF
ELECTRONICS AND COMMUNICATION ENGINEERING
CERTIFICATE
ANANDHU R
ABSTRACT
Since nano robots would be microscopic in size, it would probably be necessary for
very large numbers of them to work together to perform microscopic and macroscopic
tasks. These nano robot swarms, both those incapable of replication and those capable
of unconstrained replication in the natural environment
TABLE OF CONTENTS
LIST OF FIGURES ii
1. INTRODUCTION 1
2. LITERATURE SURVEY 3
3. ROBOTICS 5
4. NANO TECHNOLOGY 6
5 WHAT ARE NANOROBOTS? 7
6. METHODOLOGY 8
6.1 The Basic Terminology 8
6.2 Hardware 9
6.2.1 Nanosensor 9
6.2.2 Molecular Sorting Rotor 10
6.2.3 Fins 10
6.3 Nanorobot Navigation 10
6.3.1 External Navigation System 10
6.3.2 Onboard System 10
6.4 Power Sources 11
6.4.1 Internal Power Sources 11
6.4.2 External Power Sources 11
6.5 Procedure 11
7 BIOCHIPS 13
7.1 The Idea Behind Biochip 13
7.2 Components Of Biochip 14
7.2.1 Transponder 14
7.2.2 Scanner Or Reader 15
7.3 Working 16
7.4 Application 16
7.4.1 Geomics 16
7.4.2 Proteomics 16
7.4.3 Bio-diagnosis 16
8 FRACTAL ROBOTS 17
8.1 Overview 17
8.2 Inspiration And Motivation 18
8.3 Construction Of Fractal Robots 19
8.4 Applications 20
8.4.1 Space Exploration 20
8.4.2 Medical 20
8.4.3 Electronics 20
9 NANOROBOTICS IN EVERYDAY LIFE 21
9.1 Space Technology 21
9.1.1 Swarms 21
9.1.2 Space Colonization 21
9.2 Electronics 22
9.3 Medical 22
9.3.1 Treating Arteriosclerosis 22
9.3.2 Breaking Up Blood Clots 22
9.3.3 Fighting Cancer 23
9.3.4 Helping The Body Clot 23
9.3.5 Parasite Removal 23
9.3.6 Gout 23
9.3.7 Cleaning Wounds 23
9.3.8 Removing Kidney Stones 24
10 CHALLANGES 25
10.1 Technological Limitations 25
10.2 Security Threats 25
10.3 Manufacturing Cost 25
11 CONCLUSION 26
12 SCOPE OF FUTURE WORK 27
13 REFERENCES 28
LIST OF FIGURES
i
CHAPTER 1
INTRODUCTION
We've gotten better at it: we can make more things at lower cost and greater
precision than ever before. But at the molecular scale we're still very crude, that‟s
where “nanotechnology” comes in, at the molecular level.
Control System of
Nanorobot
Power Unit
1
surface textures, and chemicals; perform complex calculations; move, communicate,
and work together conduct molecular assembly; and, to some extent, repair or even
replicate themselves. Nanotechnology is the science and application of creating
objects on a level smaller than 100 nanometres. The extreme concept of
nanotechnology is the "bottom up" creation of virtually any material or object by
assembling one atom at a time. Although nanotech processes occur at the scale of
nanometres, the materials and objects that result from these processes can be much
larger. Large-scale results happen when nanotechnology involves massive parallelism
in which many simultaneous and synergistic nanoscale processes combine to produce
a large-scale result.
Many of the nano robots have very limited processing power with no artificial
intelligence as feared by most of us! They have onboard processor which is capable of
only up to 1000 operations per second. Therefore, they possess no threat whatsoever
regarding Artificial Intelligence.
Most cellular repair nanorobots do not need more than 106-109 operations/sec
of onboard computing capacity to do their work. This is a full 4-7 order of magnitude
below true human-equivalent computing at 10 teraflops (~1013 operations/sec). Any
faster computing capacity is simply not required for most medical nanorobots.
There are various ways by which this technology can be implemented in the
field of medicine. Particularly robotics, since the use of robots can enhance the way
we handle the treatment of ailments or diseases to a level where the life expectancy of
our race can be increased.
2
CHAPTER 2
LITERATURE SURVEY
Research began in nano robotics in late 1980„s.Around this time Drexler published
his research on nanosystem in which he discussed a field that derives largely from the
field of macroscopic robots. From there researched developed along two paths :
design and simulation of nano robots and manipulation/assembly of nano scale
components with macroscopic components.
Richard Feynman, US physicist and Nobel Prize winner, presented a talk to
the American Physical Society annual meeting entitled There‟s Plenty of Room at the
Bottom. In his talk, Feynman presented ideas for creating nanoscale machines to
manipulate, control and image matter at the atomic scale. Prof. Feynman described
such atomic scale fabrication as a bottom-up approach, as opposed to the top-down
approach that we are accustomed to. Top-down manufacturing it involves the
construction of parts through methods such as cutting, carving and moulding. Using
these methods, we have been able to fabricate a remarkable variety of machinery and
electronics devices. Bottom-up manufacturing would provide components made of
single molecules, which are held together by covalent forces that are far stronger than
the forces that hold together macro-scale components. Furthermore, the amount of
information that could be stored in devices build from the bottom up would be
enormous.
The first nano device design technical paper was published in 1998 in which
all the molecular and medical implications of nanotechnology were collected in one
source which is commonly referenced in medicinal applications of nano robots. While
Robotics had been used in medical field for a while nano aspect of this recently
surfaced in this area.
As research progressed, the mechanical components such as nano sized gears
made of carbon atoms were constructed. Year 1991 marked the invention AFM
(Atomic force microscope) which is a foremost tool for measuring and manipulating
the materials on nano scale. Since AFM allowed precision interaction with materials
on nano scale it was considered as robot.
3
In year 2000 United States National Nanotechnology Initiative was founded to
coordinate federal research and development in nanotechnology. It marked the start of
a serious effort in nanotechnology research. In 2000 The company Nano factory
Collaboration was founded. Aim of this was to Develop a research agenda for a nano
factory capable of building nano robots for medical purposes.
Currently, DNA machines(nucleic acid robots) are being developed. It
performs mechanical-like movements, such as switching, in response to certain
stimuli (inputs).
Molecular size robots and machines paved the way for nanotechnology by
creating smaller and smaller machine nano robots.
4
CHAPTER 3
ROBOTICS
Robotics is the branch of technology that deals with the design, construction,
operation, and application of robots, well as computer systems for their control,
sensory feedback, and information processing. These technologies deal with
automated machines that can take the place of humans in dangerous environments or
manufacturing processes, or resemble humans in appearance, behaviour, and/or
cognition. Many of today's robots are inspired by nature contributing to the field of
bio-inspired robotics.
The concept of creating machines that can operate autonomously dates back to
classical, but research into the functionality and potential uses of robots did not grow
substantially until the 20th century. Throughout history, robotics has been often seen
to mimic human behaviour, and often manage tasks in a similar fashion. Today,
robotics is a rapidly growing field, as technological advances continue research,
design, and building new robots serve various practical purposes, whether
domestically, commercially, or militarily. Many robots do jobs that are hazardous to
people such as defusing bombs, mines and exploring shipwrecks.
At present mostly (lead-acid) batteries are used as a power source. Many
different types of batteries can be used as a power source for robots. They range from
lead acid batteries which are safe and have relatively long shelf lives but are rather
heavy to silver cadmium batteries that are much smaller in volume and are currently
much more expensive. Designing a battery powered robot needs to take into account
factors such as safety, cycle lifetime and weight. Generators, often some type of
internal combustion engine, can also be used.
5
CHAPTER 4
NANO TECHNOLOGY
Atoms and molecules stick together because they have complementary shapes
that lock together, or charges that attract. Just like with magnets, a positively charged
atom will stick to a negatively charged atom. As millions of these atoms are pieced
together by nanomachines, a specific product will begin to take shape. The goal of
molecular manufacturing is to manipulate atoms individually and place them in a
pattern to produce a desired structure.
6
CHAPTER 5
WHAT ARE NANO ROBOTS?
Nano robots are the result of culmination of two technologies: robotics and Nano
technology. A nanorobot is a tiny machine designed to perform a specific task or tasks
repeatedly and with precision at nanoscale dimensions, that is, dimensions of a few
manometers (nm) or less, where 1 nm = 10-9 meter. Nanorobots have potential
applications in the assembly and maintenance of sophisticated systems. Nanorobots
might function at the atomic or molecular level to build devices, machines, or circuits,
a process known as molecular manufacturing. Nanorobots might also produce copies
of themselves to replace worn-out units, a process called self-replication.
7
CHAPTER 6
METHODOLOGY
To date, scientists have made significant progress but have not officially
released a finished product in terms of a nanorobot that functions on an entirely
mechanical basis.
Many of the nanobot prototypes function quite well in certain respects but are
mostly or partly biological in nature, whereas the ultimate goal and quintessential
definition of a nanorobot is to have the microscopic entity made entirely out of
electromechanical components. Nanorobots are essentially an adapted machine
version of bacteria. They are designed to function on the same scale as both bacteria
and common viruses so that they can interact and repel them.
Since the best way to create a nanrobot is to use another nanobot, the problem
lies in getting started. Humans are able to perform one nano-function at a time, but the
thousands of varied applications required to construct an autonomous robot would be
exceedingly tedious for us to execute by hand, no matter how high-tech the
laboratory. So it becomes necessary to create a whole set of specialized machine-tools
in order to speed up the process of nanobots construction and designing.
8
6.2 HARDWARE
6.2.1 Nanosensor
6.2.3 Fins
A fin is a surface used for stability and/or to produce lift and thrust or to steer while
traveling in water, air, or other fluid media. Nanorobot can move with the help of
these fins.
External navigation systems are one of these methods is to use ultrasonic signals to
detect the nanorobot's location and direct it to the right destination. The signals would
either pass through the body; reflect back to the source of the signals, or both. The
nanorobot could emit pulses of ultrasonic signals, which could be detected using
special equipment with ultrasonic sensors.
Using a Magnetic Resonance Imaging (MRI) device, doctors could locate and
track a nanorobot by detecting its magnetic field. Doctors might also track nanorobots
by injecting a radioactive dye into the patient's bloodstream. Other methods of
detecting the nanorobot include using X-rays, radio waves, microwaves or heat.
Onboard systems, or internal sensors, might also play a large role in navigation. A
nanorobot with chemical sensors could detect and follow the trail of specific
chemicals to reach the right location. A spectroscopic sensor would allow the
10
nanorobot to take samples of surrounding tissue, analyze them and follow a path of
the right combination of chemicals.
There are mainly two power sources used for nanorobots internal power sources and
external power sources.
A nanorobot could use the patient's body heat to create power, but there would need
to be a gradient of temperatures to manage it. Power generation would be a result of
the See beck effect. Capacitor which has a slightly better power-to-weight ratio can
also used.
External power sources include systems where the nanorobot is either tethered to the
outside world or is controlled without a physical tether. Tethered systems would need
a wire between the nanorobot and the power source. The wire would need to be
strong, but it would also need to move effortlessly through the human body without
causing damage. A physical tether could supply power either by electricity or
optically. Experimenting with in Montreal, can either manipulate the nanorobot
directly or induce an electrical current in a closed conducting loop in the robot.
6.5 Procedure
11
devices, which will allow tele-operation and advanced capabilities for medical
instrumentation.
2. The second approach is self reconfigurable modular robots also known as
Fractal robots. Self-reconfiguring robots are also able to deliberately change
their own shape by rearranging the connectivity of their parts, in order to adapt
to new circumstances, perform new tasks, or recover from damage
12
CHAPTER 7
BIOCHIPS
13
7.2 COMPONENTS OF BIOCHIP
Biochip implant consists of two components:
1. Transponder
2. Reader or scanner
7.2.1 Transponder
14
Antenna Coil: This is normally a simple, coil of copper wire around a ferrite
or iron core. This tiny, primitive, radio antenna receives and sends signals
from the reader or scanner.
Tuning Capacitor: The capacitor stores the small electrical charge sent by the
reader or scanner, which triggers the transponder. This activation allows the
transponder to send back the ID number encoded in the computer chip. As
radio waves are utilized to communicate between the transponder and reader,
the capacitor is tuned to the same frequency as the reader.
Glass Capsule: The glass capsule holds the microchip, antenna coil and
capacitor. The capsule is made of biocompatible material such as soda lime
glass. After assembly, the capsule is hermetically (air-tight) sealed, so no
bodily fluids can touch the electronics inside
The reader consists of an coil which creates an electromagnetic field that, via
radio signals, provides the necessary energy to "excite" or "activate" the implanted
biochip. The reader also carries a receiving coil that receives the transmitted code
or ID number sent back from the "activated" implanted biochip. The reader also
contains the software and components to decode the received code and display the
result in an LCD display.
15
7.3 WORKING
7.4 APPLICATIONS
Biochips have found their applications all over the world .Some of the applications
are listed below.
7.4.1 Genomics
Genomics is the study of gene sequences in living organisms and being able to read
and interpret them. The human genome has been the biggest project undertaken to
date but there are many research projects around the world trying to map the gene
sequences of other organisms.
7.4.2 Proteomics
7.4.3 Bio-diagnostics
16
CHAPTER 8
8.1 OVERVIEW
17
8.2 INSPIRATION AND MOTIVATION
There are two key motivations for designing modular self-reconfiguring robotic systems.
18
8.3 CONSTRUCTION OF NANO FRACTAL ROBOTS
The design of a fractal nanocomputer is not an easy task using conventional
principles. However, using fractal nanotechnology principles, the exercise reduces to
a fairly simple exercise where you build a fractal nanocomputer at the large scale and
providing you followed fractal principles, the computer technology scales downward
to whatever resolution limit imposed by the technology you are using.
Cube replacement
Usage of plates to construct the cubes
Using smaller fractal machines to affect self repair inside large cubes.
19
8.4 APPLICATIONS
Due to their self reconstructing properties fractal nano robots have found their
application in many fields.
8.4.2 Medical
Fractal nano robots are used in medical science .They are used in treatment of cancer,
kidney stones, blood clotting , detection and elimination of defected cells .
8.4.3 Electronics
Fractal Robots can be used in manufacturing of other electronic items with high level
of precision as they operate and manipulate objects at nano scale.
20
CHAPTER 9
NANO ROBOTICS IN EVERYDAY LIFE
Nanotechnology opens the way towards new production routes, more efficient,
performance and intelligent materials, towards new design of structures and related
monitoring and maintenance systems.
9.1.1 Swarms
Swarms are nanorobots that act in unison like bees. They theoretically act like flexible
cloth material and being composed of what is called Bucky Tubes. This cloth will act
as strong as diamond. If a nano computer is added to nanomachine a smart cloth is
found. The smart cloth could be used to keep astronauts from bouncing around in
their own aircraft while they sleep, a problem that arises when autopilot computer
fires course correction rockets. This cloth like material will be able to offset the
sudden movements and slowly move the astronauts to their position.
21
9.2 Electronics
In today‟s world very large scale integration is done on the electronic chips. Each
chip contains millions of electronic circuits. For a proper functioning each circuitry
must be designed with high percesion. As nano robots can operate at nano scale
fabrication of such chips can be easily done.
9.3 Medical
Arteriosclerosis refers to a condition where plaque builds along the walls of arteries.
Nanorobots could conceivably treat the condition by cutting away the plaque, which
would then enter the bloodstream.
Blood clots can cause complications ranging from muscle death to a stroke.
Nanorobots could travel to a clot and break it up. This application is one of the most
dangerous uses for nanorobots – the robot must be able to remove the blockage
without losing small pieces in the bloodstream, which could then travel elsewhere in
the body and cause more problems. The robot must also be small enough so that it
doesn't block the flow of blood itself.
22
9.3.3 Fighting cancer:
Doctors hope to use nanorobots to treat cancer patients. The robots could either attack
tumours directly using lasers, microwaves or ultrasonic signals or they could be part
of a chemotherapy treatment, delivering medication directly to the cancer site.
Doctors believe that by delivering small but precise doses of medication to the
patient, side effects will be minimized without a loss in the medication's effectiveness.
One particular kind of nanorobots is the clottocyte, or artificial platelet. The clottocyte
carries a small mesh net that dissolves into a sticky membrane upon contact with
blood plasma. According to Robert A. Freitas, Jr., the man who designed the
clottocyte, clotting could be up to 1,000 times faster than the body's natural clotting
mechanism. Doctors could use clottocytes to treat haemophiliacs or patients with
serious open wounds.
Nanorobots could wage micro-war on bacteria and small parasitic organisms inside a
patient. It might take several nanorobots working together to destroy all the parasites.
9.3.6 Gout:
Gout is a condition where the kidneys lose the ability to remove waste from the
breakdown of fats from the bloodstream. This waste sometimes crystallizes at points
near joints like the knees and ankles. People who suffer from gout experience intense
pain at these joints. A nanorobot could break up the crystalline structures at the joints,
providing relief from the symptoms, though it wouldn't be able to reverse the
condition permanently.
Nanorobots could help remove debris from wounds, decreasing the likelihood of
infection. They would be particularly useful in cases of puncture wounds, where it
might be difficult to treat using more conventional methods.
23
9.3.8 Removing Kidney Stones:
Kidney stones can be intensely painful -- the larger the stone the more difficult it is to
pass. Doctors break up large kidney stones using ultrasonic frequencies, but it's not
always effective. A nanorobot could break up a kidney stones using a small laser.
24
CHAPTER 10
CHALLENGES
With the help of nano robotics more advance weapons can be designed. Atomic
weapons can now be more accessible and made to be more powerful and more
destructive. These can also become more accessible with the help of nanotechnology.
Presently, nanotechnology is very expensive and developing it can cost you a lot of
money. It is also pretty difficult to manufacture, which is probably why products
made with nanotechnology are more expensive. That is why nanorobots are too
expensive.
25
CHAPTER 11
CONCLUSION
Nanomedicine will eliminate virtually all common diseases of the 20th century,
virtually all medical pain and suffering, and allow the extension of human capabilities
most especially our mental abilities.
A single nanocomputer CPU, also having the volume of just one tiny human
cell, could compute at the rate of 10 teraflops (1013 floating-point operations per
second), approximately equalling (by many estimates) the computational output of the
entire human brain. Such a nanocomputer might produce only about 0.001 watt of
waste heat, as compared to the ~25 watts of waste heat for the biological brain in
which the nanocomputer might be embedded.
26
CHAPTER 11
SCOPE OF FUTURE WORK
Teams around the world are working on creating the first practical medical nanorobot.
Robots ranging from a millimetre in diameter to a relatively hefty two centimetres
long already exist, though they are all still in the testing phase of development and
haven't been used on people. We're probably several years away from seeing
nanorobots enter the medical market. Today's microrobots are just prototypes that
lack the ability to perform medical tasks.
In the future, nanorobots could revolutionize medicine. Doctors could treat
everything from heart disease to cancer using tiny robots the size of bacteria, a scale
much smaller than today's robots. Robots might work alone or in teams to eradicate
disease and treat other conditions. Some believe that semiautonomous nanorobots are
right around the corner -- doctors would implant robots able to patrol a human's body,
reacting to any problems that pop up. Unlike acute treatment, these robots would stay
in the patient's body forever.
Another potential future application of nanorobot technology is to re-engineer
our bodies to become resistant to disease, increase our strength or even improve our
intelligence. Dr. Richard Thompson, a former professor of ethics, has written about
the ethical implications of nanotechnology. He says the most important tool is
communication, and that it's pivotal for communities, medical organizations and the
government to talk about nanotechnology now, while the industry is still in its
infancy.
Will we one day have thousands of microscopic robots rushing around in our
veins, making corrections and healing our cuts, bruises and illnesses? With
nanotechnology, it seems like anything is possible.
27
REFERENCES
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