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A single stop for all basic viva questions that you might encounter in your oral Pathology and
microbiology paper in your Dental undergraduate course. If you have questions to suggest/add, kindly
mail it to me at oralpathology.viva@gmail.com. You will be acknowledged. Every effort is made to ensure
the accuracy of the answers. Kindly use textbooks to confirm. Circulate the links widely..
Radiological features
Lesion/ Condition
Radiological appearance
Acute osteomyelitis
Apert’s syndrome
Cemento-osseous dysplasia
Central Hemangioma
Cherubism
Crouzon syndrome
Dentinogenesis imperfecta – 2
Shell teeth
Ewing’ s sarcoma
Fibrous dysplasia
Garre’s osteomyelitis
Gaucher's disease
Gigantiform cementoma
Globulomaxillary cyst
Gradner syndrome
Hemangioma
Hyperparathyroidism
Meningioma
Multiple myeloma
Odontogenic myxoma
Osteomalacia
Osteopetrosis
Vertebrae- Rugger-Jersey pattern; Ribs - Endo bone (Bone with in bone )pattern; roots are not easily
distinguishable from adjacent bone
Osteosarcoma
Intramedullary parts appears as cumulus cloud densities; sunray/ sun burst pattern; widening of
periodontal ligament; Codman’s triangle (periosteum raised like tent)
Paget's disease
Plasmacytoma
Pseudohypoparathyroidism
Chevron pulp
Psoriatic arthritis
Regional odontodysplasia
Ghost teeth
Rickets
Scleroderma
Sialdenosis (sialography)
Leafless tree
Synovial sarcoma
Spotty calcification; snow storm appearance
Synovial sarcoma
Thalassemia
Rib with in a rib appearance of rib; Hair on end or crew cut appearance; salt and pepper effect; Thin
lamina dura
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Signs&symptoms-1
Asboe-Hansen sign (also known as "indirect Nikolsky sign" or "Nikolsky II sign") refers to the extension of
a blister to adjacent unblistered skin when pressure is put on the top of the bulla.
Acroosteolysis is resorption of the distal bony phalanges. Acroosteolysis has two patterns of resorption in
adults: diffuse and band like.A diffuse pattern of resorption has a wide differential diagnosis and can
include the following: pyknodysostosis, collagen vascular disease and vasculitis, Raynaud's neuropathy,
trauma, epidermolysis bullosa, psoriasis, frostbite, sarcoidosis, hypertrophic osteoarthropathy. A band
like pattern of resorption may be seen with polyvinyl chloride exposure and Hadju-Cheney syndrome. A
mnemonic commonly used for acro-osteolysis is PINCHFO - Pyknodysostosis, Psoriasis, Injury (thermal
burn, frostbite), Neuropathy (diabetes), Collagen vascular disease (scleroderma, Raynaud's),
Hyperparathyroidism, Familial (Hadju-Cheney, progeria), Occupational (polyvinyl exposure).
Apple jelly nodules in nasal septum: It is the nodular form of the tuberculosis in nasal mucosa. It begins
in the vestibule and extends to adjoining skin and mucosa. It is the result of direct inoculation. It
presents as glistening reddish brown or skin colored nodules also known as ‘apple jelly nodules’. An
attempt to blench them with a glass slide [Diascopy] makes them more prominent, as they tend to stand
out amidst blenched surrounding. These nodules may coalesce to form characteristic ulcer with a pale
granular base and undermined margins. Untreated patients tend to progress to scarring and resultant
disfigurement of the external nose.
Arnold head: In Cleidocranial dysplasia, the fontanelles may remain open until adulthood, but the
sutures often close with interposition of wormian bones. Bosses of the frontal, parietal, and occipital
regions give the skull a large globular shape with small face. The characteristic skull abnormalities are
sometimes referred to as the "Arnold head" named after the descendants of a Chinese who settled in
South Africa and changed his name to Arnold.
Ash-leaf spots: Hypomelanic macules in Tuberous sclerosis. They are white or lighter patches of skin that
may appear anywhere on the body and are caused by a lack of melanin. These are usually the only
visible sign of diseases at birth. In fair-skinned individuals a Wood's lamp (ultraviolet light) may be
required to see them.
Auspitz's sign is the appearance of punctate bleeding spots when psoriasis scales are scraped off, named
after Heinrich Auspitz.This happens because there is thinning of the epidermal layer overlying the tips of
the dermal papillae and blood vessels within the papillae are dilated and tortuous, which bleed readily
when the scale is removed.
Borsari's sign or Borsari's line : Dermatological sign that consists of pressure by a sharp object (such as a
fingernail) producing a white line on the skin that quickly turns red. It is present in scarlet fever.
Braverman's sign is a dermatological sign that consists of fine telangiectasias around the nail
(periungually). They may be associated with connective tissue diseases.
Buffalo hump: Cushing’s syndrome, the fat relocalization in nape of the neck resembling the buffalo’s
hump
Bull neck: Diphtheria, The bacterial exotoxin may also cause severe swelling in the neck, that resembles
the bull’s hump
Carpet tack lesions: Discoid lupus erythematosus. There are follicular hyperkeratotic plugs causing a
carpet tack appearance as they project from the undersurface of the scale when it is removed from
advanced lesions. The dyspigmentation of older lesions often presents as central hypopigmentation and
peripheral hyperpigmentation.
Cerebriform tongue: Pemphigus vegetans. Also known as Furrowed /Grooved/ Lingua Fissurata/Lingua
Plicata/Lingua Scrotalis/Plicated Tongue/Scrotal Tongue
Charcot’s triad: Seen in multiple sclerosis, characterized by intention tremor, nystagmus, dysarthria
Chipmunk facies: Thalassemia. The bones of the head and face become enlarged and deformed causing
an abnormal appearance resulting in a typical “chipmunk facies” appearance. This occurs because the
bone marrow, the site of red blood cell production, becomes hyperactive [enlarged] in an attempt to
produce sufficient red cells to overcome the effects of the profound anaemia.
Chovstek’s sign: The Chvostek sign is one of the signs of tetany seen in hypocalcemia. It refers to an
abnormal reaction to the stimulation of the facial nerve. When the facial nerve is tapped at the angle of
the jaw (i.e. masseter muscle), the facial muscles on the same side of the face will contract momentarily
(typically a twitch of the nose or lips) because of hypocalcemia (i.e. from hypoparathyroidism,
pseudohypoparathyroidism, hypovitaminosis D) with resultant hyperexcitability of nerves. Though
classically described in hypocalcemia, this sign may also be encountered in respiratory alkalosis, such as
that seen in hyperventilation, which actually causes decreased serum Ca2+ with a normal calcium level
due to a shift of Ca2+ from the blood to albumin which has become more negative in the alkalotic state.
Compy's sign: Measles. White patches due to degenerated squamous epithelium occurring on buccal
mucosa and gingival.
Crowe’s sign: Neurofibromatosis. Presence of axillary (armpit) freckling in people with neurofibromatosis
type I
Dennie–Morgan fold: also known as a Dennie–Morgan line or an infraorbital fold, is a fold or line in the
skin below the lower eyelid caused by edema in atopic dermatitis. The presence of Dennie–Morgan folds
is used as a diagnostic marker for allergy
Forschemmier sign: Rubella. Forchheimer spots are a fleeting enanthem seen as small, red spots
(petechiae) on the soft palate in 20% of patients with rubella. They precede or accompany the skin rash
of rubella. They are not diagnostic of rubella, as similar spots can be seen in measles and scarlet fever.
The sign is named after Frederick Forchheimer
Gorlin sign: Ehler -Danlos Syndrome. Ability to touch the tip of the nose with tongue and touch the
elbow with the tongue
Grattage sign: Psoriasis. Gentle scraping of the surface of a psoriasis plaque with a glass slide will remove
the loosely attached scales and reveal a shiny surface peppered with fine bleeding points. These
bleeding points represent the dilated and tortuous capillary blood vessels in the papillary dermis, one of
the characteristic pathological events taking place in psoriasis affected skin. This sign is known as Auspitz
sign, which is a diagnostic sign of psoriasis.
Hamman’s crunch: Cervicofacial emphysema. Hamman's sign (AKA Hammond's sign or Hammond's
crunch) is a crunching, rasping sound, synchronous with the heartbeat, heard over the precordium in
spontaneous mediastinal emphysema produced by the heart beating against air-filled tissues.It is named
after Johns Hopkins clinician Louis Hamman. This sound is heard best over the left lateral position. It has
been described as a series of precordial crackles that correlate with the heart beat and not the
respirations. Also heard together with spontaneous pneumothorax; small and not a total lung collapse,
on the left side. Sounds like bubbles hitting the inside of the chest. Can be felt/seen. Hamman's crunch is
caused by pneumomediastinum or pneumopericardium, and is associated with tracheobronchial injury
due to trauma, medical procedures (e.g., bronchoscopy) or proximal pulmonary bleb rupture. It is
commonly seen in Boerhaave syndrome.
Hebra nose: Rhinoscleroma. Epistaxis, nasal deformity, and destruction of the nasal cartilage are also
noted along with the damage may result in anesthesia of the soft palate, enlargement of the uvula,
dysphonia, and various degrees of airway obstruction.
Higomenakis's sign: Congenital syphilis. A unilateral enlargement of the sternoclavicular portion of the
clavicle, seen in congenital syphilis. It is an end result of neonatal periostitis.
Hutchinson's sign: Herpes zoster. A skin lesion on the tip of the nose precedes the development of
ophthalmic herpes zoster
Hutchinson's triad: Congenital syphilis with Hypoplasia of incisor (Pegged laterals, screw driver shaped
central incisor and mulberry molars), Eighth nerve deafness and Interstitial keratitis.
Iris pearl’s: Leprosy. Miliary lepromas or iris pearls near the pupillary margins, which are spherical
yellowish opaque micronodules upto 2 mm in size.
Koplik's spots: Measles. Koplik spots are a prodromic viral enanthem of measles manifesting two days
before the measles rash itself. They are characterized as clustered, white lesions on the buccal mucosa
near each Stensen's duct (on the buccal mucosa opposite the maxillary 2nd molars) and are
pathognomonic for measles
Livedo reticularis: Systemic lupus erythematosus. Livedo reticularis is a common skin finding consisting of
a mottled reticulated vascular pattern that appears like a lace-like purplish discoloration of the skin.The
discoloration is caused by swelling of the venules owing to obstruction of capillaries by thrombi. It can be
caused by any condition that makes venules swell. The condition may be normal or may be related to
more severe underlying pathology. It has a broad differential diagnosis, broadly divided into possible
blood diseases, autoimmune (rheumatologic) diseases, heart (cardiovascular) diseases, cancers, and
endocrine disorders. It can usually (in 80% of cases) be diagnosed by biopsy.
Millian sign: Erysipelas. Involvement of the ear (Milian's ear sign) is a distinguishing feature for erysipelas
since this region does not contain deeper dermis tissue.
Nikolsky’s sign: Epidermolysis bullosa, pemphigus, Severe Steven –Johnson syndrome, Prophyria, Toxi
Epidermolysis Necrosis, Staphylococci Scalded skin syndrome. The sign is present when slight rubbing of
the skin results in exfoliation of the outermost layer, forming a blister within minutes.
Oil drop sign: Psoriasis. A translucent discolouration in the nail bed that resembles a drop of oil beneath
the nail plate
Ollendorf sign: Secondary syphilis. AKA Buschke-Ollendorff sign - This is a sign to be elicited in case of
secondary syphilis and cutaneous vasculitis, where there is deep dermal tenderness on pressing the
lesion (e.g., papular lesions of syphilis) with a pinhead.
Pastia’s lines: Scarlet fever. Pastia's sign, Pastia lines or Thompson's sign is a clinical sign in which pink or
red lines formed of confluent petechiae are found in skin creases, particularly the crease in the
antecubital fossa, the soft inside depression on the inside of the arm; the folding crease divides this fossa
where the forearm meets the (upper) arm (the biceps, triceps, humerus section of the upper extremity);
the inside of the elbow (the inside flexor depression (fossa) of the elbow. It occurs in patients with
scarlet fever prior to the appearance of the rash and persists as pigmented lines after desquamation.
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Peculiar Signs/symptoms-1
Acro-osteolysis: Scleroderma
Charcot’s triad: Seen in multiple sclerosis, characterized by intention tremor, nystagmus, dysarthria
CREST: Scleroderma
Hutchinson's triad: Congenital syphilis with Hypoplasia of incisor (Pegged laterals, screw driver shaped
central incisor and mulberry molars), Eighth nerve deafness and Interstitial keratitis.
Mask like face: Systemic sclerosis, Periodic paralysis, Parkinsonism, Facial palsy.
Onycholysis: Psoroasis
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Lesion/ Condition
Histopathological appearance
Actinomycosis
Anitschkow cells
Aspergillosis
Canalicular adenoma
Lymph node cortical hyperplasia; areas of stellate supparative necrosis surrounded by a band of
histiocytes
Cicatricial pemphigoid
Cytomegalovirus
Epstein’s nodule
Ewing’s sarcoma
Fibrosarcoma – intermediate
Herring bone pattern
Fibrous dysplasia
Fibrous histiocytoma
Gaucher’s disease
Hemangiopericytoma
Hodgkins lymphoma
Hurler syndrome
Junctional nevus
"Abtropfung" effect
Keratosis follicularis
Lipoblastoma
Multiple myeloma
Russell cells; sheets of plasma cells that have a cart wheel or checker board type of nuclear pattern
Mycosis fungoides
Mycosis cells or Sezary cells with cerebriform nucleus, Pautrier's micro abscess
Neurolemmoma
Oncocytoma
Paget's disiease
Paracoccidiodiomycosis
Para-neoplastic Pemphigus
Pemphigus foliaceous
suprabasilar split, Antibodies to Desmoglein 1, Prevesicular edema, Tzank cells in smear; basal cells “ row
of tombstones”
Pemphigus vulgaris
suprabasilar split, Antibodies to Desmoglein 1,3., Prevesicular edema, Tzank cells in smear; basal cells “
row of tombstones”
Pernicious anemia
Porokeratosis of Mibelli
Coronoid lamella
Radicular dentin dysplasia
Rhabdomyosarcoma – Embryonal
Rhabdomyosarcoma- pleomorphic
Regional odontodysplasia
Enamloid congromerulates
Sarcoidosis
Scurvy
Synovial sarcoma
Thalassemia
Intracellular inclusion bodies in erythrocytes - Fessas bodies –demonstrated by supravital stains; Target
cell appearance; “safety pin cells”
Verruciform xanthoma
Warty dyskeratoma
Zygormycosis
Organism are large, branching, non septate hyphae invading blood vessels
More"Bodies"
· Davidson’s body : sex chromatin in neutrophils (dumbbell shaped); "Check Barr Bodies"
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