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DIAGNOSTICS REMARKS
Rapid urase test Is a rapid diagnostic test for diagnosis of
Helicobacter pylori. Basis of the test is the
ability of H. pylori to secrete
the urease enzyme, which catalyzes the
conversion of urea to ammonia and carbon
dioxide.
Histology Provides histologic information and require
pathology processing.
Culture Allows determination of antibiotic
susceptibility.
Urea breath test A rapid diagnostic procedure used to identify
infections by Helicobacter pylori, a spiral
bacterium implicated in gastritis, gastric
ulcer, and peptic ulcer disease.
Stool Antigen Looks for foreign proteins (antigens)
associated with H. pylori infection in your
stool. As with the breath test, PPIs and
bismuth subsalicylate can affect the results of
this test, so advise to hold medication.
Barium studies of Proximal GIT Use as first test for documenting an ulcer.
GU: discrete crater with radiating mucosal
folds originating from the ulcer margin,
commonly located in the antrum.
DU: appears as a well demarcated crater,
most ofte seen in the bulb.
Endoscopy Provides most sensitive and specific
approach for examining the upper GI tract.
It permits direct visualization of the mucosa
and facilitates photographic documentation
of mucosal defect such as ulcers to determine
the source of blood loss and tissue biopsy to
rule out malignancy.
PREVENTION:
1. It may not be possible to prevent a peptic ulcer. However, reducing risk, such as quitting
tobacco use and eating a healthful diet may help.
2. People who use NSAIDs or other medications that can cause peptic ulcers should talk to a
doctor about managing ulcer-related risk. A doctor may recommend taking:
Medications with meals
Lower dosages
Alternate medications
Acid-reducing drugs
3. To prevent H. pylori spreads people should protect themselves by cooking foods thoroughly
and frequently washing the hands with soap and water.