DRUG STUDY
DRUG ORDER
(Generic name, Brand name,
classification, dosage, route,
frequency)
Generic Name: Amlodopine
Brand Name: Norvasc
Classifications: cardiovascular
agent; calcium channel blocker
Pregnancy Category:C
NURSING
MECHANISM OF ADVERSE EFFECTS OF THE
INDICATIONS CONTRAINDICATIONS RESPONSIBILITIES/
ACTION DRUG
PRECAUTIONS
Amlodipine is a Treatment of mild to moderate Hypersensitivity to CV:Palpitations, flushing  Monitor BP for therapeutic
calcium channel hypertension and angina. amlodipine. tachycardia, peripheral or facial
blocking agent that edema, bradycardia, chest pain, effectiveness. BP reduction
selectively blocks syncope, postural hypotension. is greatest after peak levels
calcium ion reflux CNS:Light-headedness, fatigue, of amlodipine are achieved
across cell headache.
6–9 h following oral
membranes of GI:Abdominal pain, nausea,
cardiac and anorexia, constipation, dyspepsia, doses.Monitor for S&S of
vascular smooth dysphagia, diarrhea, flatulence, dose-related peripheral or
muscle without vomiting.
facial edema that may not
changing serum Urogenital:Sexual dysfunction,
calcium frequency, nocturia. be accompanied by weight
concentrations. It Respiratory:Dyspnea. gain; rarely, severe edema
predominantly acts Skin:Flushing, rash. may cause discontinuation
on the peripheral other:Arthralgia, cramps, myalgia.
circulation, of drug.
decreasing  Monitor BP with postural
peripheral vascular changes. Report postural
resistance, and
hypotension. Monitor more
increases cardiac
output. frequently when additional
antihypertensives or
diuretics are added.
 Monitor heart rate; dose-
related palpitations (more
common in women) may
occur.