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The objective of the present work is orient and educate the patients individually with treatment of
hormonal substitution knowing important aspects as: knowledge and use of the treatment, number
of drugs that use the patients and the cumpletion of their therapy, at the same time the
acceptance was evaluated of the pharmaceutical attention, this carries out in 174 patients
between 40 to 75 years old of the service of Gynecology and Obstetrics at Central hospital FAP
that had been in treatment.
In order to the objective it carried out a enrolment, surveys, formulate it Registers Clinical for each
patient, triptychs was given and they spread informative videos to get education in the patients
with treatment of hormonal substitution.
According to the results, 69% of patients has information about treatment of hormonal substitution
ABSTRACT: and 31% of patients ignored the topic, even though they were in treatment; 71,8% of patients
additionally knew about the function of orienting pharmacist's medication, but alone 9,2% of
patients went to the pharmacist to request orientation about its medication; it was also found that
26,4% of patients didn't fulfill its treatment, after the attention it toasted decrease this percentage
until 19,5%; and 63,2% of patient made it occasionally, cipher decreased until 57,5% after the
attention in accordance with the results of the Register clinical.
In conclusion, is important and indispensable the pharmaceutical orientation in the treatment of
hormonal substitution to obtain the good cumpletion of the therapy and it is responsibility of
Pharmaceutical Chemist to verify, as well as to educate the patient on their medication or
treatment.
The present investigation is characterized to be prospective it has registered the facts as these
have happened. The method is expressed in the explanatory basic design and in the causal
specific design. The hypothesis to verify was: The socioeconomic situation influences significantly
in the self-medication." We worked with an objective population of 20000 families belonging to
Huancayo district, an accessible population of 1200 families bounded to The Fence and of this a
sample of 150 families was determined in aleatory form and by means of the formula of the
muestral error.
The instruments to gather the data were questionnaires of surveys: one to gather data on the
socioeconomic situation and another for the data of the self-medication. Carried out the surveys
met 150 sheets of questionnaires with the answers about the socioeconomic situation and 150
sheets of questionnaires with the answers regarding the self-medication.
Coded, the data were processed with the statistical package MINITAB version 12 and the
ABSTRACT: electronic sheet Microsoft Excel 2002 XP, we established the contingency relationship among the
low socioeconomic situation and 13% is only in high condition. On the other hand, 26% of the
families has a low self-medication and 74% a high self-medication. From the families whose
socioeconomic condition is low, 19% presents a low self-medication, and 81% a high self-
medication; the opposite happens to the families of high socioeconomic condition, where 74%
presents a low self-medication and only 26% a high self-medication.
These results reveal that the socioeconomic condition of the families influences direct and
indirectly in the self-medication. To evaluate this influence the test of independence of approaches
was used with the statistical square chi, and it
confirms when obtaining the degree of significancia of 5% and finally we find the coefficient of
contingency of 0,364.
This way, we finish: The socioeconomic situation of The the District of Huancayo influences
significantly in the medicine self-medication
El posible efecto diurético atribuido al tubérculo de Tropaeolum tuberosum R&P "mashua", por los
pobladores de la Provincia de Concepción, fue evaluado en ratas albinas hembras de la cepa
Holtzmann, las que se aclimataron durante ocho días previos al ensayo; se les mantuvo en
ayunas 18 horas antes del ensayo, sin privarlas de agua, administrándole por vía oral mediante
cánula intragástrica diferentes concentraciones del extracto acuoso. El cocimiento al 50%
presentó mayor actividad con respecto al grupo control. El resultado obtenido se comparó con los
RESUMEN:
resultados utilizando diferentes concentraciones de furosemida. El incremento de la diuresis con
Tropaeolum tuberosum R&P, es menor en un 16%) en relación a la furosemida. En los estudios
efectuados sobre toxicidad aguda en ratones de la cepa balb C53 no hubo mortalidad ni se
registraron alteraciones, determinándose que el extracto es inocuo en las concentraciones
ensayadas. El extracto acuoso del tubérculo de Tropaeolum tuberosum R&P "mashua" tiene
efecto diurético.
The possible diuretic effect attributed to the tuber of Tropaeolum tuberosum R&P "mashua", for the
residents province of Concepción, it was evaluated in rats albino females of the stump Holtzmann,
those that were acclimatized during eight previous days to the rehearsal; they were maintained in
you fast 18 hours before the rehearsal, without depriving them of water, administering him for via
oral by means of stem intragástrica different concentrations of the watery extract. The cooking to
ABSTRACT: 50% presented bigger activity with regard to the group check. The obtained result was compared
with the results using different furosemida concentrations. The increment of the diuresis with
Tropaeolum tuberosum R&P, is smaller in 16%) in relation to the furosemida. In the actual studies
on sharp toxicity in mice of the stump balb C53 didn't have mortality neither they registered
alterations, being determined that the extract is innocuous in the rehearsed concentrations. The
watery extract of the tuber of Tropaeolum tuberosum R&P "mashua" it has diuretic effect.
In the present study of experimental investigation it was treated to comprobate the effect hepatoprotector and
hepatoregenerator from the silimarina and the artichoke in the hepatic alteration derived of the chronic
intoxication with ethanol.
It was used thirty Cavia porcellus which drew round in form aleatory in groups
and sub-groups of 5 animals as following way:
Group A: Control animals
Group B: Animals intoxicated with ethanol -
Group C:
Subgroup C1: Animals treated with silimarina and then intoxicated with ethanol.
Subgroup C2: Animals treated with artichoke and then intoxicated with ethanol.
Group D:
ABSTRACT: Subgroup D1: Animals intoxicated with ethanol and then treated with silimarina.
Subgroup D2: Animals intoxicated with ethanol and then treated with artichoke.
The experimental period was 60 days, after this period the histopathology study of the liver has been realized.
The results were:
Group A: Liver normal histopathology.
Group B: Intensive steatosis, alcoholic hepatitis, generaliced necrosis. Studies of subgroups C1, C2, D1 and D2
demonstrated only different degrees of alcoholic hepatitis without histological evidences of steatosis or hepatic
necrosis.
Silimarina and artichoke in capsules administrated per oral via, pre and post intoxication with ethanol
have hepatoprotector and hepatoregenerator effect. Silimarina in capsule had better histological results.
It was also comprobated that silimarina and artichoke in capsules had effects as hepatoprotectors how
hepatoregenerator in chronic intoxication with ethanol
The roots of "arracacha" constitute one of more pleasant native foods, used traditionally like
nutritional supplement to improve the anemic states.
With the purpose Of evaluating the ant anemic activity of Arracada xanthorrhiza "arracacha",
collected of the district of Pariahuanca, I am used an experimental model to induce ferropenica
anemia in 36 rats albinos with a weight average of 250 g, who were put under during 15 days a
deficient diet in iron and extractions of blood three times per week, until obtaining concentrations
of Hemoglobin in 9 blood smaller to g/dl.
3 groups of 12 animals formed to the orange blossom each one, maintaining the same diet to
ABSTRACT: them: group 1 without supplemental, group 2 suplementada with ferrous sulphate and group 3
suplementada with ferrous sulphate and Arracada xanthorrhiza "arracacha" by 15 days. One
controlled the concentrations of hemoglobin (Hb), and hematocrit (Hto), every 5 days, the iron
concentrations (Faith) in blood, were before determined and after the experiment, being significant differences in
the results of the three groups. I am observed greater antianemic answer in the animals of group 3, with a
significant increase of the values average of iron in blood in relation to the values average of the animals of
groups 1 and 2. With the obtained results one concludes that the Arracada xanthorrhiza "arracacha* has
antianemic activity
El objetivo de esta investigación fue determinar el efecto del extracto lipofilico de pepas de Cucúrbita ficifolia
sobre el control de la hiperplasia prostética inducida por andrógenos. Para ello se obtuvo el extracto lipofilico
de pepas de C. ficifolia, mediante el secado de 1,0 Kg. de semillas (pepas) durante 72 horas, luego se
molieron, posteriormente se realizó la extracción con hexano empleando el aparato Soxhlet durante dos horas
y luego se sometió a baño maría para la eliminación del solvente. Finalmente, se realizó la purificación del
extracto con el uso del equipo de rota vapor.
Se indujo hiperplasia prostética en ratas Wistar usando el andrógeno Enantato de Testosterona por 24 días.
Se emplearon 18 ejemplares de ratas machos, con peso corporal entre 270 y 300 g; a los cuales una semana
RESUMEN: antes del ensayo se les realizó la orquiectomia, separándolos en tres grupos de 6 ratas cada uno: A) tratados
sólo con aceite vegetal (0.25ml/día); B) se les administró Enantato de Testosterona 0,02 ml/día (5mg)
conjuntamente con el extracto lipofilico de Cucúrbita ficifolia(0,25 ml/día) y C) sólo se les administró 0,02
ml/día (5mg) de Enantato de Testosterona (Testoviron® - Bayer)
Se calculó la media y desviación estándar de los pesos relativos de cada órgano para cada grupo. Los datos
se procesaron mediante un Análisis de Varianza de clasificación simple (ANOVA), cuyas medidas ajustadas
fueron comparadas mediante el Test Alfa de Cronbach, considerándose diferencias significativas para p <
0,05; determinándose que el extracto lipofilico obtenido ejerce control sobre la hiperplasia prostética inducida
por el enantato de testosterona.
The objective of this research was to use the lipophilic extract of Cucurbitaficifolia seeds for the control of
androgen-induced prostatic hyperplasia. In the first phase was obtained for lipophilic extract of Cucurbita
ficifolia seeds, dried 3.0 kg of seeds (seeds) of Cucurbita ficifolia for 72 hours, then were ground, then was
extracted with hexane the Soxhlet apparatus for two hours, was subjected to a water bath for the removal of
the solvent. Finally, there were performed the purification of the extract with the use of steam broken
equipment.
In the second phase, was induced prostatic hyperplasia in rats using the androgen Testosterone Enantate for
24 days. There were used 18 male Wistar rats, with body weight between 270 300 g; in which a week before
ABSTRACT: the test were conducted orchiectomy, but separated into three groups of six rats each one: A) only given
vegetable oil (0.25ml/day); B) were administered 0,02 ml/dia (5mg) de Testosterone Enantate (Testoviron® -
Bayer), with the lipophilic extracts of Cucurbita ficifolia (0,25ml/day) and C) alone was administered 0,02
ml/dia (5mg) of Testosterone Enantate
There were calculated the mean and standard deviation of the relative weights of each organ for each group.
The data were processed by analysis of variance of simple classification (ANOVA), which measures adjusted
were compared using Cronbach's Alpha Test, considering differences significant at p <0.05. From this result it
was determined that lipophilic extracts of Cucurbita ficifolia makes an effective control of androgen-induced
prostatic hyperplasia.
The morning-after pills, emergency contraceptives are oral female consisting of levonorgestrel,
where its effectiveness is 75% to 89% and during the past year in Latin America has increased the
use of more than 50%, while in Peru 70%, hence the objective of this research was to determine
how the consumption of the morning-after pills in pharmaceutical establishments of the city of
Huancayo, carried out through a descriptive research carried out by one survey of 4 questions
ABSTRACT: applied in 36 pharmaceuticals companies based sample of 140, and nonparametric hypothesis
testing, with use of Chi square, found that consumption as a result of the morning-after pills in
pharmaceutical establishments of the city of Huancayo is not high, and concluded that the average
age is between 18-20 years with higher education level and know the dosage form
El propósito de esta investigación fue determinar cuáles son los factores que contribuyen a que
las recetas médicas no sean atendidas en pacientes ambulatorios de la farmacia del Hospital El
Carmen de Huancayo; se hizo un estudio con diseño causal durante los meses de Setiembre a
Diciembre del 2010 y se analizó en una muestra de 2616 recetas médicas no atendidas;
RESUMEN: encontrándose como resultados que los factores que más contribuyeron a las recetas médicas no
atendidas fueron las prescripciones que no pudieron adquirir los pacientes por falta de dinero en
un 34.29%, con un promedio de recetas médicas no atendidas de 4,56% del total de
prescripciones, cuya procedencia correspondió a medicina general en 20.99% y que los
medicamentos cuya recetas médicas no fueron atendidos son los antiinfiamatorios como el
Meloxican, Flogozan y Lisalgil en 27.37%.
The purpose of this research was to determine the factors that contribute to that the prescriptions
are not handled in outpatient pharmacy in Hospital El Carmen of Huancayo; an applicative
descriptive study was carried out during the months of September to December 2010 and
analyzed a sample of 2616 unmet medical prescriptions; finding results that the factors that
contributed to the -unmet medical prescriptions were prescriptions could not acquire patients due
ABSTRACT: to lack of money in a 34.29%, with an average of unmet medical prescriptions of 4.56% of the totai
number of prescriptions, whose origin accounted for general medicine at 20.99% and that
medicines whose prescriptions were not serviced are anti-inflammatory drugs like the
MeloxicanFlogozan and Lisalgil in 27.37%.
The present research had as objective to determine the levels of self-medication in people of
Huancayo district. For that it was applied a inclined no probabilistic sampling, by inquiring 600
persons (315 female and 285 male) which acquired medicaments in 8 sell points of Arcángel
pharmacy shops, between february to august of 2011, without a medical prescription and
willingness accepted being inquired. Higher levels of self-medication in female sex were between
25 and 55 years old (51,43%), the 38,73% had complete high school and 54,60% was employed;
while in male sex the 44,91% were between 25 and 55 years old, the 36,14% had complete high
ABSTRACT: school and 57,54% was employed. The 61,0% of female people declared "sometimes" to acquire
medicaments without medical prescription; 45,4% to acquire antibiotics; 44,8% to acquire
antiinflammatories and 66,3% "never" ansiolitics. The 63,5% of male people declared "sometimes"
to acquire medicaments without medical prescripción; 43,2% to acquire antibiotics; 43,5% to
acquire antiinflammatories and 67,7% "never" ansiolitics. The 32,8% of inquired stated "always" to
self-medicated by own decision; and "sometimes" 49,4% by relatives advises; 55,2% by friends
advises; 57,2% by publicity and 43,5% by pharmacy worker's advises
The present study aimed to identify and quantify the errors associated with prescription medication
in pediatric. Se service has carried out a descriptive, longitudinal prospectively and consisted of
866 prescriptions review of pediatric services, unit Neonatal Intensive Care Unit of the Regional
Hospital Pediatrics Maternal and Child "El Carmen"
We evaluated the quality indicators such as the, dose, route, frequency, dosage form, dosage,
duration of treatment, concentration, readability, abbreviations and inadequate international name
of the drug.
3850. was detected in error indicators called, medication errors. 100% of prescriptions had at least
one indicator in error.
ABSTRACT: The 98 % of prescriptions presented error in dosage form , 97.7 % had error in the concentration ,
63.7 % in duration of treatment, 51.6 % in abbreviations inadequate illegibility those 50.2 % , 46.9
% route of administration , 16.9 % international name , dosage 6.8 % , 6.7 % in the dose and
frequency of administration for 6% of the prescriptions.
Medication errors obtained in the study are high and consistent with other authors in prevalence
associated with the prescription of which are potentially harmful to the patient and therefore must
be prevented, avoided and corrected, so that encourages responsible of prescription, self-evaluate
their actions and reflect on the quality of services provided and the authorities view error
prevention strategies, focusing on the system itself and not the individual
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