Академический Документы
Профессиональный Документы
Культура Документы
Valuation
Assessment of Value of a
New Medical Product
• Find collaborators
• Learn new skills and mentors
through live and through Profiles
online courses.
Workforce
Collaboration • Gain access to
• Longitudinal Development: expertise through
programs for Education & Training biostatistical or
mentored projects regulatory
and skills consultations
Tools and
Technologies
• Research resources -
• Funding - pilot grants
access to technologies,
clinical research facilities,
and the community
Harvard Catalyst leverages resources and networks across its 26 affiliates and serves as a
hub for existing but otherwise disparate information.
Example: Profiles is a tool to search contact, publication, and social network information for Harvard
affiliated investigators
T-domain overview
T1 T2 T3 T4
offerings
Applied Biostatistics
Network Medicine
Advanced Courses: Understanding Biomarker Science
Often covering more Medical Device Development
than one T-space;
technical learning Imaging Modalities in C/T Research
Introduction to ‘Omics
Team Science
Cross-Cutting
Learning: Adaptive Ethics
skills that are woven Mentoring
throughout AND
offered as Leadership Skills
independent courses
Grant Writing and Communications
Regulatory
CIMIT Introduction
Contact:
John Collins, COO
jcollins11@parners.org
Cell: +1-617-899-3364
CIMIT: Consortia for Improving Medicine with Innovation
and Technology
NIBIB
VA Boston NHLBI
A Center at
1998 2000 2002 2004 2006 2008 2010 2012 2014 2016
International
Affiliates
Competitive
Cooperative
Agreements Page - 2
CIMIT’s Mission:
Find Facilitate
➢ Site Miners ➢ Experienced
➢ Program entrepreneurs from
Leaders network
➢ CIMIT Forums ➢ Find collaborators &
➢ Conferences refine proposals
➢ Courses
Fund ➢ Anticipate and
address issues (e.g.
➢ Request for ➢ Innovation Grants
regulatory, IP
Proposals ➢ Accelerator Awards
compliance, etc.)
➢ Needs ➢ Adoption & Diffusion
Awards ➢ Create options and
Solicitations
➢ Prizes plans for funding &
➢ Growing profile commercialization
➢ Young Clinician
Awards ➢ CRAASH Course
Page - 4
The Healthcare Innovation Cycle:
“Translation”
Page - 5
What often really happens … Inexperienced teams make
mistakes that doom, derail or stall promising innovations
Lack of
Awareness
Too Too Good,
Expensive Too Special
SoC Need
Use Idea Does not fit
Resistance to
Progress: Workflow
Change
- Clinical
A&L - Market/Bus. PoC
Published &
- Regulatory Lost IP
Regulatory “Wall” - Technical
VoS PoF Too Complicated
© CIMIT 2018
Page -7
DIGITAL TRANSFORMATION
CREATING
IMPACT
Confidential – do not copy or distribute © 2017 Brigham Digital Innovation Hub. All Rights Reserved.
BRIGHAM INNOVATION JOURNEY
Confidential – do not copy or distribute © 2017 Brigham Digital Innovation Hub. All Rights Reserved. 2
IMPACT SINCE 2013
5 iHUB SUPPORTED
BWH SPINOUTS 21 2 BWH HACKATHON
PROJECTS WENT ON
TO FORM COMPANIES
• BrainSpec by Alexander Lin, PhD DEPARTMENTS
• Volalytix by Sophia Koo, MD ENGAGED
• Fertilex by Hadi Shafiee, PhD with “Frequent Flyers” from
Pulmonary/Critical Care,
• Astarte by Kate Gregory, PhD, RN Radiology and OB/GYN
• Postercast by Rick Kaufman, MD
1000+ ATTENDEE
S@ 25+ EVENTS
Confidential – do not copy or distribute © 2017 Brigham Digital Innovation Hub. All Rights Reserved.
iHub: A DIGITAL HEALTH INNOVATION ENGINE
Our mission is to drive more seamless, efficient, patient-centered and safe care for our patients
through the development, evaluation, use and commercialization of digital health platforms and tools.
We make it easy for BWH to test out digital innovation by supporting a bi-directional flow of innovation…
Confidential – do not copy or distribute © 2017 Brigham Digital Innovation Hub. All Rights Reserved. 4
LEADING INFRASTRUCTURE
ACCELERATING DIGITAL INNOVATION
“Open for Business”
Confidential – do not copy or distribute © 2017 Brigham Digital Innovation Hub. All Rights Reserved. 5
iHub: WAYS TO ENGAGE
iHub supports all levels of engagement, whether you’re a tech-savvy clinician, a seasoned innovator
who wants to learn about digital health, or an operations manager in search of a solution.
Attend monthly events Request a market scan Work with iHub to match a
(Speaker Series, Digital challenge to a market
Research Forum) Workshop your idea at Open solution, and facilitate
Office Hours (Thursdays) collaboration and testing
Confidential – do not copy or distribute © 2017 Brigham Digital Innovation Hub. All Rights Reserved. 6
Resources and Strategies for Enhancing Translational
Product Development:
Exploring the Local Ecosystem
October 2018
Resources for Boston Children’s Translational Endeavors
TIDO Services
• Identify research and discoveries with commercial potential
• Build commercialization strategy
Patents and
• Manage intellectual property Licensing
• Fund proof-of-concept
• Structure commercial deals
• Manage alliances
• Support research Business Technology
Development/ Development
Marketing Fund
Technology Development Fund
TDF is a seed-stage academic catalyst fund dedicated to translating high-impact academic
technologies into the independently-validated, later-stage opportunities sought by industry
partners and investors.
Tech Dev
Fund
23
Technology Development Fund
TDF Model
TDF Award
Funding Technical
Mentoring / Project
($50K- Support
$150K)
Coaching Management
(CRO)
Technology Development
EVALUATION CRITERIA
• BCH mission: pediatric impact
• Medical need, research significance
• Technical feasibility
• Impact of funding on translation
• Clear commercial potential
• Will the project generate or strengthen IP?
TDF 2017: Mentoring
Broader
network/market
BCH TIDO/TDF research
Supporting Development with TDF Funds/
Defining business model and business plan
TDF History 2009-Present
Thank you!
• Post-award - Engages Pilot awardees at start, middle, and end of project period
• Project Management
• Pre-award - Identifies key decision points and milestones in project plans,
• Co-Development Deals
#hcatpge