NCM 107- MCN EDC- confinement (p.

187)
Folic acid- prevents neural tube defects EDD- delivery
SDGs Karyotyping- visual presentation of
chromosome pattern of individual
1. No poverty
2. Good health & well-being Alpha-fetoprotein- by fetal liver; in amniotic fluid
3. Quality education & maternal serum (MSAFP); glycoprotein
4. Gender equality
^ level of alpha-fetoprotein- open spinal & abd
5. Clean water & sanitation
wall defects, openings allow more AFP to enter
6. Responsible consumption & production
mom’s circulation than usual; open neural tube
7. Partnership & goals
defects (ex. Spinal bifida & anencephaly)
Genetics:
See p. 196
Genotype- genetic make-up
Chorionic villi sampling:
Phenotype- physical appearance; genotype &
 Retrieval
environment
 Chorion cells are located by ultrasound
Homozygous- identical genes  Thin catheter is inserted vaginally or a
biopsy needle abdominally or
Heterozygous- 2 diff genes
intravaginally & number of chorionic
Dominant- allele of gene that suppresses cells are removed for analysis
expression of alternate allele  Report chills & fever bc of infection or
symptoms of threatened abortion
Recessive- allele masked by dominant allele (uterine contractions & vaginal bleeding)
(appears only in homo condition)
 Cells removed by CVS karyotyped or
Autosomal dominant disorders- person w/ submitted for DNA analysis
dominant gene for it is usually a hetero Amniocentesis
Common findings of disorders:  Aspiration of 20cc AF from uterus thru
1. Parents have abd wall
2. Sex is unimportant  15th-20th week, AF has reached about
3. History of disorder in other family 200mL
members  Determine genetic disorders, sex & fetal
maturity
Autosomal recessive inheritance:
Advantage over CVS:
1. Both parents are clinically free
2. Sex is unimportant  O.5% risk of sponti abortion
 Women observed for 30mins lead to—
X-linked dominant inheritance- transmitted only hemorrhage, infection of AF, & puncture
by females of fetus
X-linked recessive inheritance: AF- note color, amount & consistency
 Both affected- AD  Color of water- normal
 Father affected- AD  Slightly yellow- tinge (normal in late
 Both recessive- AR pregnancy)
Naegele’s Rule- estimating EDD  Strong yellow color (blood
incompatibility)
  Green color (meconium staining, fetal
distress)
L/S ratio p.197
LGA- large for gestational age
PUBS- p.198
Ultrasonography- p. 194
Fetoscope- p.198
Nursing responsibilities
1. Alerting about procedures
2. Explain general screening tests
3. Supporting a couple during waiting of
results
4. Assisting couples in values clarification,
planning & decision making based on
test results
5. Provide info about disorders
6. Reassure about disorder inheritance
7. Allow future reproduction

AOV – 24weeks; 500-600g

Genetic counselling- p. 159
Urinalysis- p. 250
Reproductive system- p. 82
McDonald’s method of estimating FH: FH in cm
correlates w/ weeks of gestation between 20-
31 weeks
Gravida- pregnant
Nulligravida- not pregnant
Primigravida- p. 237