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Learning Targets
At the end of the session, I can:
1. Differentiate active transport from passive transport;
2. Explain the mechanism of diffusion in relation to real life experiences.
LESSON REVIEW/PREVIEW
Activity 1: Identify the following structure of a cell by choosing your answer in the word pool. Write your
answer on the space provided before each number.
______________________1. This organelle is also known as the “powerhouse” of the cell. MITOCHONDRIA
______________________2. This organelle is also known as the “digestive organ” of the cell. LYSOSOMES
______________________3. This is the domain where human beings belong. EUKARYA
______________________4. Antibiotics fight foreign organisms that invade our body. These foreign organisms fought by
antibiotics belong to what domain? BACTERIA
______________________5. This is the outer layer that maintain cell’s shape and protects cell from the mechanical damage.
They are made of cellulose which can be found in plant cells and prokaryotic cells. CELL WALL
______________________6. The region in prokaryotic cells, consisting of concentrated mass of DNA. NUCLEOID REGION
______________________7. Aids in synthesis of secretory and other proteins from bound ribosomes, adds carbohydrates to
glycoproteins and produces new membrane. ROUGH ENDOPLASMIC RETICULUM
______________________8. Houses chromosomes made of chromatin and contains nucleoli. NUCLEUS
______________________9. Domain where Cyanobacteria, Chlamydia, Spirochetes and Green Sulfur Bacteria belong.
BACTERIA
______________________10. Consist of diverse group of prokaryotic organism that thrive in wide variety of environments
which include Methanobacteria, Thermophiles and Halophiles. ARCHAEA
Cell Transport
Molecules passes and travel from cell to cell through the semi-permeable cell membrane (plasma
membrane).
Molecules have a type of energy called thermal motion (heat). One result of thermal motion is diffusion,
the movement of molecules of any substance so that they spread out evenly into the available space.
Any substance will diffuse down its concentration gradient, the region along which the density of a
chemical substance decreases.
RULE: In the absence of other forces, a substance will diffuse from where it is more concentrated to where it is
less concentrated.
Pre-printed Notes
Osmosis
Osmosis is the diffusion of water across a selectively permeable from the region of lower solute
concentration to the region of higher solute
concentration. It will continue to diffuse until it is in
equilibrium, with both side of the membrane in equal
concentration.
Kinds of cell Transport
1. Passive Transport
A diffusion of substance across a membrane with
no energy investment.
Facilitated Diffusion – a passive transport in which polar
molecules pass through the membrane via membrane
transport protein.
2. Active Transport
Uses energy to move solutes against their gradients
In active transport, the molecule binds to a specific
carrier protein and transport it to the other side.
Guided Practice
Activity 6: Study the illustration
below and answer the questions
that follow.
Tonicity describes a solution’s concentration relative to its surrounding. Since the concentration gradient
causes water to move across the membrane, tonicity is also the ability of a solution to cause a cell either
to take in more water or take out water.
Activity 7: Arrange the jumbled letter from column A and write it in column B. Then match column B to
a term related to it column C. A letter in column C may be used once, twice, or not at all.
COLUMN A COLUMN B COLUMN C
Learning Targets
At the end of the session, I can:
1. Trace the steps in cell cycle;
2. Recognize the importance of cell cycle in the perpetuation of life.
C Y E C G Q P F G S W J O F Y
J Y I S U W X X I V U G E T X
W O T R A U L S E B K U L Y O
S S B O E H E P U T I R C B N
O P N C K H P P G D L L Y Z F
R Y H E T I C R S S J C C K U
C F I N N P N C E B Q H L N K
C W Y T C H O E E T R E L F T
C S K R W B O Z S O N M E J K
K K G O B P S Y M I I I C D K
B O Y M P X D O C Y S Z Z T N
CELLCYCLE CENTROMERE CHROMOSOME ORGANELLES
N CYTOKINESIS
N T E W GROWTH
R S G R O INTERPHASE
W T H V SYNTHESIS
Z
D L Y R F O Q L R I S H H M Q
Pre-Printed Notes
The Cell Cycle
Most of a cell’s lifetime is spent growing. This cycle of growth and division is called the CELL CYCLE. The
cell cycle is divided into the five phases.
Interphase
A newly formed cell begins its life by undergoing a period of growth and activity called interphase.
During this phase, the new cell is hard at work carrying out the tasks of life: taking in food, converting
energy, discarding wastes, growing and differentiating. In addition, it is making copies of its genetic
material and duplicating its organelles in preparation for cell division.
Interphase occurs in three distinct stages (G1, S phase, G2):
- The cell undergoes intense growth. The cell increases in volume by imbibing water and nutrients and building new
protoplasm and cytoplasmic organelles. The cells of many organisms spend most of their lives in this phase.
2. S phase (synthesis)
- The cell makes a precise copy of the DNA molecule in each of its chromosomes. Once copied, the two identical molecules
remain together, joined by the centromere.
3. G2 phase
- The final stage of interphase. The cell continues to grow and begins to make preparations for cell division. Synthesis of
RNA and proteins occurs during this stage.
- Once the G2 phase is finished, the cell has successfully completed interphase.
M phase (Mitosis)
- During this phase the two copies of each chromosome are separated.
a. Prophase
- the chromatin coiled condensing into discrete chromosomes, observable under a light microscope
- nucleoli disappear mitotic spindle begin to form
- centrosomes move away from each other
b. Prometaphase
- Nuclear envelopes fragments
- Chromosomes have become even more condensed
- Each of the two chromatids of each chromosome now has a kinetochore, protein structure located at the
centromere
- Some of the microtubules attach to the kinetochores, becoming “kinetochore microtubules” which move
chromosomes back and forth
c. Metaphase
- Longest stage of mitosis; often lasting about 20 minutes
- Centrosomes are at opposite poles of the cell
- Chromosomes convene at the metaphase plate
- Kinetochores of each sister chromatids are attached to the kinetochore microtubules from opposite poles
d. Anaphase
- Shortest stage of mitosis
- Each chromatid thus become a full-fledged chromosome
- Each chromosome begins moving to opposite poles of the cell while their attached kinetochore microtubules
shorten
- The cell elongates
- By the end of Anaphase, the two ends of cell have equivalent – and complete – collections of chromosomes
e. Telophase
- Two daughter nuclei from in the cell
- Nuclear envelope forms in each daughter cell
- Chromosomes become less condensed
C phase (Cytokinesis)
- Formation of cleavage furrow in animal cells
- Final phase of the cell cycle. It divides in half and becomes two, new identical cells.
Activity 9: Answer the following questions by encircling the letter of your answer.
1. At what checkpoint is also known as the “restriction point” in mammalian cell?
A. G1 B. G2 C. M Phase
2. Where does the cell go if it does not receive a “go signal” after passing by the restriction point?
A. G0 B. G1 C. G2
3. What checkpoint is also known as the spindle checkpoint?
A. G1 B. G2 C. M Phase
4. This checkpoint ensures that all chromosomes have attached to the spindle in preparation for
Anaphase.
A. G1 B. G2 C. M Phase
5. It is a control point in cell cycle where stop and go-ahead signals regulate the cycle.
A. Cell cycle checkpoint B. Cytokinesis C. Interphase
Differentiating Mitosis from Meiosis
Learning Targets
At the end of the session, I can:
1. Differentiate somatic cells from sex cells;
2. Compare mitosis from meiosis.
Mitosis Meiosis
Number of divisions 1 2
Pre-printed Notes
Somatic cell - undergoes mitosis, non-sex cell, diploid, and identical with the parent.
Germ cell/Sex Cells - undergoes meiosis, sex-cell, haploid, non-identical with the parent, brings genetic information.
Mitosis – the process by which the nucleus of a eukaryotic cell divides to form two new nuclei, each containing a complete set
of the cell’s chromosomes.
Meiosis- it is a nuclear division in which the diploid or somatic number of chromosome is reduced in half.
Stages of Meiosis
Meiosis I: Separates Homologous Chromosomes
1. Prophase I – fusing together of each pair of homologous chromosome, a process called synapsis. As they lie together
lengthwise, they exchange one or two sections which is called crossing over.
2. Metaphase I – Pairs of homologous chromosomes now arranged on the metaphase plate with one chromosome in each
pair facing each pole. The centromeres of each of the homologous pair of chromosome become attached to the spindle,
one above, the other below the equatorial plate.
3. Anaphase I – Homologs move toward the opposite poles, guided by the spindle apparatus/fiber.
4. Telophase I & Cytokinesis – formation of cleavage furrow; produces two cells, each of which has just one member of each
homologous pair chromosomes that was present in the original cell. There is no replication between Meiosis I and Meiosis
II.
Answer key:
1. prophase 1 4. Metaphase II
2. Anaphase 1 5. Zygonema/prophase 1
3. cytokinesis
Tracing the Photosynthetic Process
Learning Targets
At the end of the Sunlight + H2O + NADP+ + chlorophyll NADPH + O2 + ATP session, I can:
1. Outline the photosynthetic
process;
2. Differentiate light reaction and dark reaction in photosynthesis.
Pre-Printed Notes
Stages of Photosynthesis
light, oxygen
Column A Column B
____1. In what cellular organelle does photosynthesis a. mitochondria
occur? b. chloroplast
c. carbon dioxide and water
____2. What does the word photosynthesis mean? d. oxygen and glucose
e. ATP and NADH
____3. Aside from oxygen, what else is produced f. using light to make something new
by the light reaction of photosynthesis? g. sugar
h. light reaction
____4. What are the end products of photosynthesis?
Answer key:
1.b 2. f 3.g 4. d 5.c
Activity 9: Use the words to fill in the empty spaces in the paragraph below.
Photosynthesis is a process where plants create their own FOOD using sunlight. Plant leaves absorb red and blue LIGHT
into their leaves, reflecting green. This is why most plants are green in color. A chemical called CHLOROPHYLL is found inside
most plant cells. This is the substance that absorbs sunlight.
Meanwhile, plants are absorbing WATER (H2O) through their roots and storing it within their cells. When the sunlight
hits the water molecules, the water breaks apart into hydrogen and oxygen. Plants also take CARBON DIOXIDE (CO2) in through
holes in their leaves, called stomata. This is a plant’s way of BREATHING. When the carbon dioxide combines with hydrogen, a
type of sugar called GLUCOSE is formed. This is a plant’s food, and it uses this energy to live and grow. The extra oxygen
molecules are released back into the atmosphere.
CARBON DIOXIDE, CHLOROPHYLL, GLUCOSE, FOOD, LIGHT, BREATHING, WATER
Describing Cellular Respiration
Learning Targets
At the end of the session, I can:
1. Identify products of cellular respiration;
2. Compare aerobic and anaerobic respiration.
Pre-printed Notes:
Cellular Respiration –This is the breakdown of sugars (glucose) and other food molecules in the presence of
oxygen to carbon dioxide and water, generating a large amount of ATP, the energy currency that “pays for”
cellular work.
Cellular respiration can produce up to 32 ATP molecules for each glucose molecule. The rest of the energy is released as heat.
Stages of Aerobic Cellular Respiration:
2. Krebs cycle/citric acid cycle - Pyruvic acid is processed and removed of its remaining hydrogen, electrons, and carbon. Carbon
dioxide is a by-product and is released as metabolic waste.
- ATP is produced through substrate- level phosphorylation for cell use
- hydrogens and electrons produced in the cycle are sent to the electron transport chain
- 2 cycles
3. Electron Transport Chain (ETC) - Consists of a sequence of carrier molecules that are capable of
oxidation and reduction chemiosmosis – the mechanism of ATP synthesis.
- Converts kinetic energy of hydrogen electrons to the high-energy phosphate bonds of ATP via chemiosmosis,
while the hydrogen ions and electrons are bonded with oxygen to form water
- Water is released as a by-product
Developmental Activity (5 min)
Activity 5: Using a Venn diagram, compare and contrast Aerobic and Anaerobic respiration.
Anaerobic respiration – This process is also known as fermentation which occurs when there is no oxygen available to oxidize
glucose to form ATP. Instead, the glucose is either converted to alcohol or lactic acid producing little energy as compared with
the aerobic respiration. In wine making, yeast cells ferment the sugar from the fruit (i.e. grapes, cane, etc.) to pyruvic acid via
glycolysis pathways to ethanol in the cytoplasm of the cell. In humans, lactic acid fermentation occurs in muscles where oxygen
becomes depleted resulting in localized anaerobic conditions that causes muscle stiffness and cramps.
General Equation for Alcoholic Fermentation:
pyruvate carbon dioxide + acetaldehyde ethanol
General Equation for Lactic Acid Fermentation:
Pyruvate + NADH lactic acid
Answer key:
a. Glycolysis
b. Kreb’s cycle
c. Electron Transport
chain (ETC)
d. Oxygen;
e.Electron Transport
Chain (ETC)
f. CO2;
g. H2O
Answer Key:
1. Aerobic 2. Anaerobic 3. Aerobic 4. Anaerobic 5. Aerobic