Академический Документы
Профессиональный Документы
Культура Документы
www.health.gov.mt/ nbts/bldgroup.htm
1. ABO
2. Rhesus
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Antigen-Antibody reaction
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Antigens & Antibodies in the ABO System
™ There are two antigens (A & B antigens) and two antibodies
(anti-A & anti-B) that are responsible for the ABO types.
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Blood Type Antigens on RBCs Antibodies in Serum
A A anti-B
B B anti-A
AB A+B none
O none anti-A + anti-B
™ Type A people have the A antigen on the surface of their red cells
=> anti-A antibodies will NOT be produced because they would
cause the destruction of their own blood.
www.biologymad.com/ Immunology/Immunology.htm 7
www.bh.rmit.edu.au/.../ resources/genetics4.htm 9
(Donor)
(Receiver) (Receiver) (Receiver)
(A Ag) (B Ag) (A & B Ag)
www.anselm.edu/.../ genbio/geneticsnot.html 10
Cont. ABO System
www.bh.rmit.edu.au/.../ resources/genetics1.htm 11
™ Rhesus gene complex: found on chr. 1 with two alleles for each of
three genes that are close together
-> C or c, E or e, and D or not D (usually expressed as d). ™ It
is the presence of D that is important.
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Rhesus Genotypes & Phenotypes
™In Western Europe, 85% of individuals are Rhesus Positive & nearly all
of the Orientals & American Indians.
™However, 30% of Basques from Northern Spain are Rhesus Negative.
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•During birth, small amounts of foetal blood leak into the mothers
circulation, through the placenta.
•If the foetus is Rh+ and mother is Rh-, the foetal cells (RBCs)
stimulate the production of anti-D antibody in the mother.
These antibodies cross back into the second Rh+foetus and cause
lysis of the RBCs of the second Rh+foetus.
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Cont. Rhesus factor
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http://www.infoplease.com/ce6/sci/A0841716.html
Rhesus Incompatibility
www.homehealth-uk.com/ medical/bloodgroup.htm;
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Procedure
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Results
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