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1. Which class of anti-fungal drugs work by inhibiting squalere epoxidase?

a. Echinocondins
b. Allylamines
c. Polyesnes
d. None of the above

Answer: B. Allylamines

2. Which antifungal drugs class work by targeting glucans?


a. Allyamines
b. Polyenes
c. Echinocandins
d. NONE OF THE ABOVE

Answer: C. Echinocandins

3. Acyclovir is an antiviral medication primarily used as a treatment for herpes simplex,


chickenpox, and shingles. This drug is contraindicated to the following, EXCEPT:
a. Pregnant patients
b. Patients with renal impairments
c. Encephalitic patients
d. Hypoxic patients

Answer: C. Encephalitic patients

4. What are antibacterial agents used for?


a. Treatment for diabetes
b. To kill germs
c. Destroy and slow down the growth of bacteria
d. None of the above

Answer: C. Destroy and slow down the growth of bacteria

5. It inhibits proteins synthesis by binding to 50S ribosome subunit, stimulates transfer


RNA dissociation, thus inhibiting amino acid incorporation into proteins.
a. Macrolides
b. Aminoglycosides
c. Sulfonamide
d. Tetralides

Answer: A. Macrolides

6. Which of the following statement correctly pair the antifungal drugs with their likely
mechanism of actions?
a. Amphotericin B – inhibits thymidylate
b. Griseofulvin – interferes with microtubule function
c. Flucytosine – inhibits fungal mycolic acid synthesis
d. Miconazole – inhibits DNA-dependent RNA polymerase

Answer: C, Flucytosine
7. Special concerns in using anti-microbials in newborns and young children?
a. Sulfonamides can be safely given to newborns.
b. Tetracyclines should not be administered to children below the age of 8.
c. Newborns should not be given chloramphenicol because they are unable to
metabolize the drug adequately.
d. Both B and C

Answer: C

8. Inhibition of fungal squalene epoxidase is this antifungal drug’s mechanism of action:


a. Ketoconazole
b. Fluconazole
c. Terbinafine
d. Nystatin

Answer: C, Terbinafine

9. This drug is used for prevention of relapses: Plasmodium Vivax and Plasmodium ovale
only.
a. Chloroquine
b. Primaquine
c. Quinine
d. Mefloquine

Answer: B, Primaquine

10. Suitable for treatment of bacterial meningitis caused by H. influenza:


a. Cefotoxime (Clarofan)
b. Cephalexin (Keflex)
c. Cephalothin (Keflin)
d. Cefadroxil (Duncef, Ultracef)

Answer: A. Cefotoxime

11. Mechanisms of action: Amoxicillin (amoxil polyvox)


a. Inhibits bacterial cell wall biosynthesis
b. Interferes with transpeptidation preventing peptidoglycan chain causing linkage.
c. BOTH
d. Neither A nor B.

Answer: C, Both.

12. The nurse administers a dose of heparin to a client. Which client’s statement most
concerns of the nurse?
a. I have been itchy all over
b. I have several new bruises
c. My stomach has been upset
d. My temperature has been elevated

Answer: B. I have several new bruises.


13. An azole most commonly used for topical treatment of candidiasis:
a. Amphotericin B
b. Clotrimazole
c. Griseofulvin
d. Flucytosine

Answer: B. Clotrimazole

14. All of these mechanisms of action of antibacterial drugs, can be classified EXCEPT:
a. Inhibition of cell wall synthesis
b. Inhibition of protein synthesis
c. Inhibition of fungal disease
d. Inhibition of nucleic acid synthesis

Answer: C. Inhibition of fungal disease

15. Antibacterial regarded as generally safe to prescribe in pregnancy


a. Erythromycins
b. Cephalosporins
c. Tetracyclines
d. A and B

Answer: D. A and B

16. Mechanism of Action: Amoxicillin (Amoxil Polymox)


a. Inhibits bacterial cell wall biosynthesis
b. Interferes with transpeptidation preventing peptidoglycan chain crosslinking
c. Both
d. Neither

Answer: C. both

17. Type of antimicrobial substance active against bacteria and is the most important type
of antibacterial agent fighting bacterial infections
a. Anti-fungal
b. Antibiotic
c. Analgesic
d. Antidiuretic

Answer: B. Antibiotic

18. It inhibits cross linking of peptidoglycan in the final step of cell wall synthesis
a. Cefepime
b. Cefotaxime
c. Penicillin
d. Macrolides

Answer: C. Penicillin

19. Which antifungal drug, at high dose, has an antiandrogen effect?


a. Ketoconazole
b. Clotrimazole
c. Voriconazole
d. Fluconazle
20. Antifungal medication used to treat ___________?
a. Diabetes Mellitus
b. Ringworm
c. Heart Problems
d. Dengue

Answer: B. Ringworm

21. Which of the following is not an imidazole antifungal?


a. Clotrimazole
b. Sertacomazole
c. Tiacomazole
d. Terconazole

Answer: D. Terconazole

22. Antibiotics are powerful medicines that help to fight:


a. Viruses
b. Bacteria
c. All microbes
d. Germs

Answer: B. Bacteria

23. What is the common drug for antifungal?


a. Miconazole
b. Danazol
c. Diazepam
d. Biogesic

Answer: A. Miconazole

24. Approved for treating mucocutaneous and cutaneous infections with candida
a. Ketoconazol
b. Fluconazole
c. Nystatin
d. Danazole

Answer: C. Nystatin

25. What is the common drug for malaria?


a. Malarone
b. Insulin
c. Biogesic
d. Ascorbic Acid
Answer: A. Malarone

26. Which of the following inhibit herpes virus?


a. Amantadine
b. Acylovas
c. Oseltamivis
d. Azidothymidine

Aswer: B. Acylovas

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