Riosa, Desiree Mae L.

Group 5

Drug Name Mechanism of Administration Indication Contraindication Adverse Effect Nsg. Responsibilities
Action

MIdazolam Classification: Dosage:  Preprocedural Hypersensitivity Rarely  Assess level of

Anti-anxiety IV: inject 2.5 mg sedation. to cardioresp sedation and
agents, for 2 minutes  Aids in the benzodiazepines. adverse events, level of
sedative/hypnotics (never as bolus) Chronic nausea, consciousness
induction of
IM: 0.07-0.08 respiratory vomiting, throughout and
Action: anesthesia and as insufficiency. headache, for 2-6 hr
mg/kg part of balanced
Physiologic hiccoughs, following
Mechanism anesthesia laryngospasm, administration.
Route: dyspnoea,  Monitor BP,
• Short-term
IM, IV hallucination, pulse and
sedation
oversedation, respiration
• Postoperative
drowsiness, continuously
amnesia ataxia, rash, during IV
Pharmacologic paradoxical administration.
Mechanism reactions, Oxygen and
• Acts at many amnesic resuscitative
levels of the CNS episodes. equipment
to produce should be
immediately
generalized CNS
available.
depression.
 If overdose
• Effects may be occurs, monitor
mediated by pulse,
GABA, an respiration ,
inhibitory and BP
neurotransmitter. continuously.
Maintain
patent airway
Riosa, Desiree Mae L.
Group 5

and
assist ventilatio
n as needed. If
hypotension
occurs,
treatment
includes IV
fluids,
repositioning
and
vasopressors.
 The effects of
midazolam can
be reversed
with flumazenil
(Romazicon).