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BIO260_SitiSarahAzman
INTERESTING FACTS ON HUMAN BODY
Your body contains more than 200
types of cells that do different jobs
Corneas are
the only tissues
that don't
require blood.
The length of your thumb is about
the same as that of your nose.
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IN BIOLOGY, CELL = BASIC UNIT OF
LIVING THINGS
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ANATOMY & PHYSIOLOGY OF ANIMAL
TISSUE
1. Epithelial ✴ Hyaline
✴ Shape cartilage
✴ Thickness ✴ Blood
2. Connective 3. Muscle
✴ Loose ✴ Skeletal
Connective ✴ Smooth
Tissue ✴ Cardiac
✴ Fibrous
4. Nervous
Connective
✴ Sensory neuron
Tissues
✴ Adipose tissue ✴ Interneuron
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What is anatomy?
What is physiology?
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ALWAYS KEEP IN MIND THAT IN
ANATOMY & PHYSIOLOGY CORRELATES!
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EPITHELIAL TISSUE (EPITHELIUM)
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GENERAL CHARACTERISTICS OF
EPITHELIAL TISSUE
‣ The tissue is avascular
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GENERAL CHARACTERISTICS OF
EPITHELIAL TISSUE
‣ Epithelial tissue has polarity (2 different sides)
• Basal side:
‣ One of its surfaces adhered to the basement membrane. Basement
membrane is located between the epithelium tissue and
connective tissues.
• Apical side:
‣ The other surface of the epithelium tissue is free; exposed to air or
fluid.
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BASAL VS APICAL?
x
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TYPES OF EPITHELIAL TISSUES
Epithelial tissue
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COVERING AND LINING EPITHELIUM
Epithelial tissues that cover or line surfaces are classified by:
the cell thickness (number of cell layers)
Simple (single cell layer)
Stratified (mul0ple 0ers of cells)
Pseudostratified (a single layer of cells varying in height)
cell shape.
Squamous (Fla5ened, wider than tall; like floor 0les)
Cuboidal (Cube-shaped, as tall as wide; like dice)
Columnar (Column-shaped, taller than wide; like bricks
standing on end)
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COVERING AND LINING EPITHELIUM
where diffusion
is important
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SIMPLE SQUAMOUS EPITHELIUM
• Description:
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SIMPLE CUBOIDAL EPITHELIUM
Description:
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SIMPLE COLUMNAR EPITHELIUM
▸ Description: single layer of tall cells
with round to oval nuclei; some has
cilia
▸ Function:
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PSEUDOSTRATIFIED COLUMNAR
EPITHELIUM
• Description:
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STRATIFIED SQUAMOUS EPITHELIUM
• Description:
• The new cells are pushed outward, replacing the cells that are
sloughed off (regenerates from below)
• Function:
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STRATIFIED SQUAMOUS EPITHELIUM
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STRATIFIED CUBOIDAL EPITHELIUM
▸ RARE…
▸ Function: Protection
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STRATIFIED COLUMNAR EPITHELIUM
▸ RARE…
▸ Description: Several cell layers, basal cells usually
cuboidal.
▸ Function: Protection, secretion
▸ Location: In male urethra, large ducts of some glands
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TRANSITIONAL EPITHELIUM
• Description: Modified type of stratified epithelium
• Resembles both stratified squamous and cuboidal
• Basal cells - cuboidal or columnar
• Surface cells - squamouslike
• All cells are able to modify their shape when placed under
different conditions.
• Function:
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TYPES OF EPITHELIAL TISSUES
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GLANDULAR EPITHELIAL TISSUES
✴ Epithelium containing a single or a cluster of specialized
epithelial cells that synthesize and secrete a given
product (e.g. mucus, bile, milk, sweat, oil, enzyme,
hormones…)
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GLANDS
Glands
Organs made up of glandular epithelium
that that synthesize and secrete a
given product onto the skin, or into a
body cavity or interstitial fluid
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CLASSIFICATION OF EXOCRINE GLANDS
(BASED ON STRUCTURE)
Exocrine Glands
Unicellular Multicellular
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EXOCRINE GLANDS: UNICELLULAR
Unicellular gland:
Single-celled gland
Product: mucin
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EXOCRINE GLANDS: MULTICELLULAR
▸ Gland made of many cells
▸ Consists of two parts
▸ Epithelium-derived duct
▸ Secretory unit made of secretory
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CLASSIFICATION OF EXOCRINE GLANDS
(BASED ON MODE OF SECRETION)
Exocrine Glands
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Merocrine glands Apocrine glands Holocrine glands
secretory products are secretory products are assembled The whole epithelium cell that
released by exocytosis in in the distal portion of epithelial contains secretion material
membrane-bound granules cell and pinches off. disintegrates from the epithelium
or vesicles. The bottom part of the cell then and then releases all its content.
Examples: salivary glands, develops to become a full Mitosis division produces new
epithelium cell and is ready to epithelium cells.
exocrine portion of pancreas,
secrete again. Example: mammary Examples: sebaceous glands.
mammary gland (protein
gland (lipid portion of milk only)-
portion only)
lactating breast.
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MUSCLE TISSUE
The major function of muscles is to produce motion (moves the
body and its parts)
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TYPES OF MUSCLE TISSUES
Striated or Voluntary or
Muscle types Example
non-striated involuntary
Skeletal
Cardiac
Smooth
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PROPERTIES OF MUSCLE TISSUES
▸.
▸.
▸.
▸.
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MUSCLE TISSUE TERMINOLOGY
• Fiber –skeletal, cardiac & smooth muscle cell
• Myofilaments
• Sarcoplasm –cytoplasm
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SKELETAL MUSCLE
✦ Description: Long, cylindrical, multinucleate cells, striated (due to
overlapping filaments give the cells striped appearance under
microscope)
✦ Function:
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SKELETAL MUSCLE
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CARDIAC MUSCLE
✦ Description:
✦ .
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CARDIAC MUSCLE
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SMOOTH MUSCLE
✦ Description:
✦ .
✦ .
✦ Function: propels substances or objects along internal
passageways; involuntary control (churning of stomach,
construction of arteries)
✦ Location: mostly in walls of hollow organs (digestive tract,
urinary bladders and arteries
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SMOOTH MUSCLE
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SUMMARY MUSCLE TISSUE
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NERVOUS TISSUE
Function :
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NERVOUS TISSUE
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INTRODUCTION TO NEURONS
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STRUCTURE OF NEURONS
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STRUCTURE OF NEURONS
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TYPES OF NEURONS
✴ Three types of neurons
✴ Sensory neurons
✴ Excited by specific stimuli
✴ .
✴ Interneurons
✴ Integrate sensory information
✴ .
✴ Motor neurons
✴ Relay commands from brain and spinal cord to muscles and
glands
✴ .
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TYPES OF NEURONS
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TYPES OF NEURONS
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FUNCTIONS OF NEURONS
✦ Elongated neurons receive and
transmit information
✦ Dendrites: Neuron 1
✦ Axon:
Neuron 2
✦ Synapse is a junc0on between
neurons
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INTRODUCTION TO GLIA/ GLIAL CELL
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FUNCTIONS OF GLIA/ GLIAL CELL
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TYPES OF GLIAL CELLS
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ASTROCYTES
• Astrocytes are found in the brain's capillaries and form
the blood-brain barrier that restricts what substances can
enter the brain.
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MICROGLIA
• Microglia are extremely small cells of the central nervous
system that remove cellular waste and protect against
microorganisms.
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OLIGODENDROCYTES
• Oligodendrocytes are central nervous system structures
that wrap some neuronal axons to form an insulating
coat known as the myelin sheath.
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SCHWANN CELLS
• Schwann Cells are peripheral nervous system structures
that wrap some neuronal axons to form an insulating
coat known as the myelin sheath.
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SCHWANN CELLS
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CONNECTIVE TISSUE
▸ Found all over animal’s body
▸ Function:
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CONNECTIVE TISSUE
▸ Cells
▸ Fibroblasts - secrete the fibers and ground substance of the
extracellular matrix
▸ Adipocytes - store fat
▸ Macrophages - ingest and remove foreign material or damaged cells
▸ mast cells - trigger inflammation
▸ Lymphocytes - involved in immune defense and inflammation
▸ Fibers (extracellular matrix)
▸ collagen fibers
▸ reticular fibers
▸ elastic fibers
▸ Ground substance (extracellular matrix)
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CONNECTIVE TISSUE
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EXTRACELLULAR MATRIX
▸ The extracellular matrix in the connective tissue is composed of ground
substance and fibers.
▸ Ground substance
▸ Substance that fills the space between the cells and contains the fibers.
▸ Fibers
▸ collagenous fibers,
▸ elastic fibers,
▸ reticular fibers.
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1.COLLAGENOUS FIBERS
▸ Made of collagen.
▸ Most abundant protein in
animal kingdom.
▸ Nonelastic–do not tear easily
when pulled length-wise.
▸ Also called “white fibers”
▸ Example – skin
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2. ELASTIC FIBERS
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3. RETICULAR FIBER
▸ Very thin and branched.
▸ Composed of collagen and continuous with collagenous
fibers.
▸ Form a tightly woven fabric (network) that joins connective
tissue to adjacent tissue.
▸ This network acts as a supporting
mesh in soft tissues such as liver,
bone marrow, and the tissues and
organs of the lymphatic system
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THE FUNCTIONS OF CONNECTIVE
TISSUES ARE:
▸ Establishing a structural framework for the body
▸ Hyaline cartilage
▸ Areolar
▸ Fibrocartilage
▸ Adipose
▸ Elastic cartilage
▸ Reticular
▸ Bone (osseous) tissue
▸ Dense connective
tissue ▸ Blood
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LOOSE CONNECTIVE TISSUE
▸ Most widespread connective tissue
▸ Types:
▸ Adipose tissue
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LOOSE CONNECTIVE TISSUE - AREOLAR
▸ Description:
▸ The most widespread connective tissue.
▸ Has all three fiber types that run in all directions allowing flexible
movement.
▸ Cells:
▸ Fibroblasts – secrete the proteins of the extracellular fibers.
▸ Macrophages – an ameoboid cells that roam the maze of fibers,
engulfing bacteria and the debris of dead cells by phagocytosis.
▸ Mast cells – secretes heparin and histamin(anticoagulant) in
body defense.
▸ Plasma cells – secretes a glycoprotein material to form a matrix.
▸ Fibers in a semifluid matrix
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LOOSE CONNECTIVE TISSUE - AREOLAR
▸ Function:
▸ As packing materials, holding
organs in place.
▸ Fills in between organs and
wraps nerves, blood vessels and
muscle.
▸ Plays important role in inflammation
▸ Location:
▸ Widely distributed under epithelia of body
▸ In the subcutaneous tissue –attaches skin to muscle below the skin.
▸ packages organs, surrounds capillaries to underlying tissues
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LOOSE CONNECTIVE TISSUE - ADIPOSE
▸ Description:
▸ Specialized form of loose connective tissue.
▸ Matrix very sparse, closely packed adipocytes
▸ Stores fat in adipose cells distributed throughout matrix.
▸ Function:
▸ Pads and insulate the body and stores fuel as fat
molecules (droplets).
▸ Swells when fat is stored.
▸ Shrink when fat is used as fuel.
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LOOSE CONNECTIVE TISSUE - ADIPOSE
▸ Location:
▸ Under skin, around kidney, within abdomen
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LOOSE CONNECTIVE TISSUE -
RETICULAR
▸ Description:
▸ Resembles areolar, but the only fibers in its matrix are reticular fibers.
▸ Reticular cells lie on the
network
▸ Function:
▸ As a framework in many
organs especially blood base
organ such as liver, spleen and
lymph nodes.
▸ Location:
▸ Lymphoid organs
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DENSE CONNECTIVE TISSUE
▸ Dense, irregular
▸ Dense, regular
▸ Dense, elas0c
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DENSE CONNECTIVE TISSUE
▸ Has high density of extracellular fibers (collagenous
fibers)
▸ Relatively smaller proportions of ground substance and cells
Ground substance
Fibers > and/or cells
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DENSE CONNECTIVE TISSUE - REGULAR
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DENSE CONNECTIVE TISSUE - ELASTIC
▸ Found in structure that must expand
▸ e.g: lung tissue and walls of large arteries
▸ Composed of
elastic fibers
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CARTILAGE
▸ Flexible connective tissue in animals
▸ Types of cartilage:
▸.
▸.
▸.
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TYPES OF CARTILAGE
▸ Abundance of collagenous fibers embedded in
rubbery extracellular matrix
▸ To support and cushion joints between bone, the rib
cage, the ear, the nose, the bronchial tubes and
the intervertebral discs
▸ Made of a substance called chondroitin-sulfate (a
protein-carbohydrate complex).
▸ Secreted by cells called chondrocytes.
▸ Chondrocytes sit in lacunae, a small cavities in
their matrix, that scattered spaces within the
ground substance.
▸ The lacunae may sit single, in pairs, triple or
quadruple.
▸ Make cartilage strong yet flexible.
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HYALINE CARTILAGE
▸ Description:
▸ Amorphous but firm matrix
▸ Have large protein fibers and
predominantly collagen.
▸ Chondroblast > Chondrocytes (mature)
lie in lacunae
▸ Function:
▸ supports and reinforces
▸ Location:
▸ Cover the ends of bone to reduce
friction, embryonic skeleton and skeleton
of cartilaginous fish –shark and rays.
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HYALINE CARTILAGE
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ELASTIC CARTILAGE
▸ Description:
▸ Similar to hyaline cartilage but more elastic fibers in
matrix
▸ Fibers are clearly visible – best to compared with hyaline
cartilage.
▸ Function:
▸ Maintain shape of structure while allowing great flexibility
▸ Location
▸ Found in the pharyngotympanic (eustachian) tubes,
epiglottis, and external ear (pinna)
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ELASTIC CARTILAGE
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FIBROUS CARTILAGE
▸ Description:
▸ Matrix similar to hyaline cartilage but less firm
▸ A type of cartilage that contains mainly fine collagen fibers arranged in
layered arrays.
▸ More open or spongey architecture with gaps between lacunae and
collagen fiber bundles.
▸ Function:
▸ Have tensile strength
▸ Able to absorb compressive shock
▸ Location:
▸ Pubic symphysis
▸ intervertebral disks
▸ Disc of knee joint
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FIBROUS CARTILAGE
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BONE
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▸ A mineralized connective
tissue - that form
skeleton supporting the
most vertebrate body.
▸ Deposit a matrix of
collagen.
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FUNCTIONS OF BONE
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2 TYPES OF BONE:
1. Compact bone
2. Spongy bone
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COMPACT BONE
▸ Forms the outer shell of all bone and also the shafts in
long bones.
▸ Compact bone consists of living cells, 30% collagen and
glycoprotein fibers, and about 70% inorganic substances.
▸ Main mineral deposits are calcium hydroxyapatite
crystals – a calcium phosphate and magnesium, sodium,
hydrogencarbonate and chloride ions.
▸ In long bones, only the outer area is hard and compact,
the inner area is filled with spongy bone tissue called
marrow.
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SPONGY BONE (CANCELLOUS BONE)
▸ Found at the expanded heads of long bones and fills
most irregular bones.
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BONE
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TRABECULAE
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BLOOD TISSUE
▸ Blood, is a bodily fluid that has a liquid extracellular
matrix.
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FUNCTIONS OF BLOOD
▸ Supply of nutrients such as glucose, amino acids and
fatty acids (dissolved in the blood or bound to plasma
proteins).
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CELLULAR COMPONENTS SUSPENDED
IN THE PLASMA
▸ Erythrocytes – r
▸ Leukocytes –
▸ Platelets –
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KEY CONCEPT: ANIMAL TISSUES
‣ Epithelial tissue covers the body’s surface ; lines its
internal tubes; forms the glands
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▸ Oct2015
▸ Distinguish between cardiac and skeletal of muscle
tissues
4 marks
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▸ March2016
▸ Describe two types of simple epithelial tissue
5 marks
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REFERENCES
th
▸ Biology, Campbell & Reece 10 ed
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THANK YOU
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