FATIMA UNIVERSITY MEDICAL CENTER

Dept. of Family Medicine and Community Health

Valenzuela City

Drugs & dosages

 Drug

Any substance that

brings about change in
biologic function
through its chemical
action
DOSAGE
COMPUTATION
 DOSAGE COMPUTATION

• A (per dose) =
Wt (kg) x Pediatric dose x denominator of stock dose
Numerator of stock dose
• A ÷ frequency
–(ie: every 8 hrs, divide the drug by 3.)
 Ex #1
5 year old male
Wt: 20 kg
Pediatric dose: 10-20 mg/kg/dose
Paracetamol 250 mg/5 ml
 20 KG

10mg/kg/dose 20mg/kg/dose

200mg/dose 400mg/dose

200mg/dose x 400mg/dose x
5ml / 250mg 5ml / 250mg

4mL 8mL
EMPIRICAL DOSE
0-3 mos 0.3 ml

4-6mos 0.6 ml
7-9mos 0.9 ml
10-12 mos 1.2 ml
2-5 yo 2.5ml
>5 yo 5 ml
PRESCRIPTION
WRITING
 MEDICAL PRESCRIPTIONS
•written orders of the MD to the pharmacist
•directing that a certain drug or combination of
drugs be dispensed in stated forms and
amounts for the treatment of a particular
patient.
 STRUCTURE OF A PRESCRIPTION
• A. Patient’s data
• B. Superscription
• C. Inscription
• D. Subscription
• E. Signa
• F. Certificate of physician
 SUPERSCRIPTION

• consist of the symbolRx

– stands for the latin verb recipe
– take thou
 INSCRIPTION

•contains the names and amount of remedial

agents and appropriate vehicles to be taken by
the patient.
 SUBSCRIPTION
• embodies the physician’s direction to the
Pharmacist
• method of preparation of the medicine
– as in making and mixing solutions
– or in cases of solid preparations:
• number of pills or tablets to be dispensed.
 SIGNA
• abbreviated as sig or S
• the direction to the patient or nurse which the
pharmacist is required to put in specific and
lucid manner on the label of the medicine
container
• details of administration: frequency and time
of administration.
CERTIFICATE BY THE PHYSICIAN
• signature of the physician
• license number
• narcotic license number of prescribing
regulated or prohibited drugs.
• final guarantee of the genuineness of the
order.
 Fatima University Medical Center
120 MacArthur Highway, Valenzuela City

Name: Juan Dela Cruz Age/Sex: 28/M

Address: Marulas Valenzuela City Date: 07/1/2014

Rx Amoxicillin 500 mg/ capsule #21

(Himox)

Sig: Take 1 capsule every 8 hours for 7 days.

Dr. Tiu/JI Galvez

Lic. No. 123456
 ANTI HELMINTHIC
GENERIC NAME BRAND NAME PEDIATRIC DOSE FREQUENCY PREPARATIONS

Pyrantel Combantrin 11mg/kg/day Once every 3 125-250mg/5ml

Pamoate months

Mebendazole Antiox 2.5mg/kg/day Every 12 hours 50-100 mg/5ml

NSAIDS/ ANTI INFLAMMATORY

GENERIC NAME BRAND NAME PEDIATRIC DOSE FREQUENCY PREPARATIONS

Paracetamol Tempra, Calpol, 10-20mg/kg/DOSE Every 4 hours PRN 100mg/ml

Tylenol, Biogesic, for temp 37.8C 120mg/5ml
250mg/5ml

Ibuprofen Dolan 5-10mg/kg/dose Every 6 hours 100mg/5ml

40mg/mL

Mefenamic Acid Ponstan, Dolfenal 6.5mg/kg/dose Every 6 hours 50mg/5ml,

250mg/tab
500mg/tab
 RESPIRATORY DRUGS

GENERIC NAME BRAND NAME PEDIATRIC DOSE FREQUENCY PREPARATIONS

Salbutamol Ventolin 0.075-0.1 Every 8 hours 2mg/5ml

Asmalin mg/kg/dose

Terbutaline Bricanyl, 0.05-0.75 Every 8 hours 0.3 mg/ml,

Pulmoxel mg/kg/day 1.5 mg/5ml

Procaterol HCL Meptin 0.25 ml/kg/dose Every 12 hours 5mcg/ml

 Mucolytics
GENERIC NAME BRAND NAME PEDIATRIC DOSE FREQUENCY PREPARATIONS

Ambroxol Ambrolex, Empirical <2 yrs old Every 15mg/5ml-pedia

Mucosolvan 12 hours\ 3omg/5ml-adult
>2 yrs old Every 30mg tab
8 hours
Carbocisteine Loviscol, Solmux, Empirical Every 8 hrs 100mg/5ml
250mg/5ml
50mg/ml
500mg/cap
Bromhexine Bromoxine, Empirical Every 6-8 hours 4mg/5ml
Bisolvon
 Decongestants
GENERIC NAME BRAND NAME PEDIATRIC DOSE FREQUENCY PREPARATIONS

Phenylpropanola Disudrin Empirical Every 8 hours for 12.5mg/5ml

mine 5 days
 GENERIC NAME BRAND NAME PEDIATRIC DOSE FREQUENCY PREPARATIONS

Penicillin V Sumapen, 50,000-100,000 Every 6 hours 125mg/5ml=

Megapen IU/kg/day 200,000IU
250mg/5ml=
400,000 IU
Amoxicillin Himox 30-50 mg/kg/day Every 8 hours 100mg/ml
125mg/5ml
250mg/5ml
250mg/cap
500mg/cap
Co-amoxiclav Augmentin 30-50 mg/kg/day Every 8 hours 156.25mg/5ml
228.5mg/5ml (bid)
312.5mg/5ml
375mg/tab
625mg/tab
1g/tab (bid)
 GENERIC NAME BRAND NAME PEDIATRIC DOSE FREQUENCY PREPARATIONS

Sultamicillin Unasyn 25-50 mg/kg/day Every 12 hours 250mg/5ml

375mg/tab
750mg/tab
 Antistaphylococcal penicillins/
Penicillinase Resistant

GENERIC NAME BRAND NAME PEDIATRIC DOSE FREQUENCY PREPARATIONS

Cloxacillin Na Encloxil, Orbenin 50-100 mg/kg/day Every 6 hours 125mg/5ml

250mg/5ml
250-500mg/cap
Oxacillin Na Cilvex, Wydox 50-100 mg/kg/day Every 6 hours 500mg/vial
 CEPHALOSPORINS
GENERIC NAME BRAND NAME PEDIATRIC DOSE FREQUENCY PREPARATIONS

Cefalexin Ceporex, Cefalin, 30-50 mg/kg/day Every 8 hours 100mg/ml

(1G) Zeporin 250mg/5ml
125mg/5ml
250mg/cap
500mg/cap
Cefuroxime Zinnat, Zincef, 10-20mg/kg/day- Every 12 hours 125mg/5ml
(2G) Romicef mild 250 mg/5ml
20-30mg/kg/day- 250mg/cap
mod. 500mg/cap
40-50mg/kg/day-
severe
Cefaclor Clorcef, Ceclor, 20-40 mg/kg/day Every 8 hours 125mg/5ml
(2G) Verzat 250 mg/ 5ml
50mg/ml
250mg/cap
500mg/cap
Ceftriaxone Rocephin 20-80 mg/kg/day PARENTERAL ONLY 1g/vial
(3G)
 MACROLIDES

GENERIC NAME BRAND NAME PEDIATRIC DOSE FREQUENCY PREPARATIONS

Erythromycin Erythrocin, 30-50 mg/kg/day Every 6 hours 40mg/5ml

Erycar, Stiemycin 100mg/2.5ml
200mg/5ml
Azithromycin Zithromax 10 mg/kg/day OD x 3-5 days 200mg/5ml

Clarithromycin Klaricid 7.5 mg/kg/day Every 12 hours 125mg/5ml

250mg/5ml
500mg/tab
 METABOLIC INHIBITORS

GENERIC NAME BRAND NAME PEDIATRIC DOSE FREQUENCY PREPARATIONS

Co-Trimoxazole Bactrim, TMP: 5-8 Every 12 hours TMP: 40mg/5ml

Bactrinol mg/kg/day SMX:200mg/5ml
SMX: 25-40 TMP: 80mg/5ml
mg/kg/day SMX: 400mg/5ml
 ANTI PROTOZOAL

GENERIC NAME BRAND NAME PEDIATRIC DOSE FREQUENCY PREPARATIONS

Metronidazole Flagyl 30-50 mg/kg/day Every 8 hours 125mg/5ml

OTHER
COMPUTATIONS
 Ideal Body Weight

0-5 months Age in months x 600 + 3000 gms

6-12 months Age in months x 500 + 3000 gms

2-6 years Age in years x 2 + 8 kg

7-12 years Age in years x 7 – 5 kg ÷ 2

 NUTRITIONAL STATUS
GOMEZ CLASSIFICATION
• Actual Body weight x 100
Ideal Body Weight
 GOMEZ CLASSIFICATION
• Above 120 : Obese
• 110-120 : Overweight
• 90- 110 : No malnutrition
• 80- 89 : First degree malnutrition
• 70-79 : second degree malnutrition
• <70 : Third degree malnutrition
 WATERLOWE CLASSIFICATION

•Stunting = Actual height x 100

Ideal Height for Age
WATERLOWE CLASSIFICATION

• >95 % :No stunting

• 90-95% : Mild stunting
• 80-89% :Moderate stunting
• < 80% : Severe stunting
WATERLOWE CLASSIFICATION
•Wasting = actual weight x 100
Ideal weight for actual ht
WATERLOWE CLASSIFICATION

•>90% : No wasting
•80-89 % : Mild wasting
•70-79 % : Moderate wasting
•<70% : Severe wasting
 EXAMPLE
• 2 year old female
• Wt: 9 kg
• Ht: 79 cm

• GOMEZ
• Actual Body weight / Ideal Body Weight x 100
– IBW: 2 X 2 + 8 = 12 kg

– 9kg / 12kg X 100 = 75%  Second degree

Malnutrition
 EXAMPLE
• 2 year old female
• Wt: 9 kg
• Ht: 79 cm

• WATERLOWE (Stunting)
– Actual height / Ideal Height for Age x 100
–
– 79 cm / 89.62 cm X 100 = 88%  Moderate
Stunting
 EXAMPLE
• 2 year old female
• Wt: 9 kg
• Ht: 79 cm

• WATERLOWE (Wasting)

– Actual weight / Ideal weight for actual ht x 100

– 9 kg/ 10.41 X 100 = 86.5%  mild wasting

THANK YOU! 