Академический Документы
Профессиональный Документы
Культура Документы
Corresponding author
P. Ravisankar
Flat no. 501, Door no.4-1-16,
Sapthagiri Sesha Sai Sadan,
4/2, Lakshmipuram, Guntur-522007,
Andhra Pradesh, India.
banuman35@gmail.com
09000199106.
2512
Please cite this article in press as P. Ravisankar et al. Acne-Causes And Amazing Remedial Measures For Acne. Indo American
Journal of Pharm Research.2015:5(07).
Copy right © 2015 This is an Open Access article distributed under the terms of the Indo American journal of Pharmaceutical
Page
Research, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
www.iajpr.com
Vol 5, Issue 07, 2015. P. Ravisankar et al. ISSN NO: 2231-6876
INTRODUCTION
Medically, acne termed as acne vulgaris [1] a common form of skin disease that involves the oil glands at the base of hair
follicles. Acne is an infection of the skin. It commonly occurs during puberty when the sebaceous (oil) glands come to life. The said
glands are stimulated by male hormones produced by the adrenal glands of both males as well as females. The form of acne is
called acne vulgaris, which implies "common acne". It is an infection of the skin, caused by changes in the sebaceous glands. The red
color comes out of the inflammation of the skin owing to the infection existed in the skin. Acne is a common skin disease with
pimples which is common in young people. Most of the people develop acne but it primarily affects teenagers who are undergoing
hormonal changes. Acne may be mild with few, occasional pimples, moderate with inflammatory papules, or may be severe with
nodules and cysts and the treatment depends on the type of condition of the disease. Acne is common during puberty, which is a stage
when a person is shaped from a child into an adult, owing to secretion of high levels of hormones. Acne becomes common as people
reach adulthood.
Human skin has pores (tiny holes) which connect to oil glands located under the skin. The glands are connected to the pores
via follicles which are small canals. These glands produce Sebum an oily liquid which carries dead skin cells through the follicles to
the surface of the skin. A small hair grows through the follicle out of the skin. Pimples grow when these follicles get blocked, resulting
in an accumulation of oil under the skin. The skin consists of tiny holes called pores that can become blocked by oil, filth and bacteria
which paves way to develop a pimple or “zit.” Under the blocked pore, oil builds up. Skin bacteria then grow very quickly. This
infection makes the skin become swollen and red, which becomes visible. And if skin is repeatedly affected by such state, acne may
appear but it is not a life-threatening condition, though painful when it turns violent. In human beings the common places acne disease
usually occurs are the face, neck, chest, back, and upper arms. Acne that appears on the face chronically may cause permanent
scarring, yet not dangerous.
Scientists from the Washington University school of medicine found that there are good and bad strains of bacteria that
determine the severity and frequency of developing acne. They explained in the journal of investigative dermatology (March 2013
issue) that not all acne bacteria trigger pimples, in fact, one strain they identified can help keep the skin pimple free [2]. To express in
a nut shell, skin cells, sebum and hair can clump together into a plug, which gets infected with bacteria resulting in a swelling. A
pimple starts to develop when the plug begins to break down.
Acne vulgaris
The most common form of acne; usually affects people from puberty to young adult hood. Acne vulgaris is a general skin
condition characterized by the development of seborrhea, comedones, nodules, papules, pustules and cyst. It comes in the areas of the
skin with plentiful hair growth such as in the upper chest, back, legs and face. Sebecaous glands get infected and clogged.
Development of several large and small eruptions.
Types of pimples
Pimples or spots come out when the skin produces much more oil, causes breeding bacteria which clog the existing pores
creating swelling and redness on the skin. Pimples are not at all contagious. Out of various kinds of pimples the most common types
2513
Whiteheads – Remain under the surface of skin and are very small.
Page
Blackheads – Vividly look black and rise to the surface of the skin but are not formed due to dirt.
Black heads are not black because of dirt they are black in color. Generally air oxidises the protein called keratin.
www.iajpr.com
Vol 5, Issue 07, 2015. P. Ravisankar et al. ISSN NO: 2231-6876
Papules – They are small tender pink bumps which are clearly seen on the skin.
Pustules – Pustules (pimples or zits) are red at the bottom level consisting of pus at its top and can be looked on the surface of the
skin.
Nodules – Clearly visible on the surface of the skin. They are painful, large, solid pimples existing deeply in the skin and can be seen
on the skin surface.
Cysts – Clearly visible on the surface of the skin. They are deeply rooted, painful and pus filled and easily prone to form scars.
Acne-symptoms
Acne can be found anywhere on your body. Commonly it develops on the face, back, neck, chest, and shoulders. If you have
acne, you will typically notice pimples that are white or black in appearance. Both blackheads and white heads are known as come
downs. Black heads open at the surface of the skin giving them a black appearance. White heads are closed just under the surface of
the skin, giving them a white appearance. While whiteheads and blackheads are the most common types of acne, other lesions can
occur. Inflammatory lesions namely papules, pustules, nobules and cysts are more likely to create scarring of the skin. [5-9].
plug is termed as blackhead. The plugged hair follicle gradually emerged as a bump. As the follicle expands, the wall become rupture,
allowing normal skin bacteria enter into the deeper layers of the skin, duly creating inflammation as a result of which the surface of
the skin produces a pustule and deeper inflammation become pimple and if penetrates more deeper a cyst is formed which may leave
incurable permanent scars on the skin.
Page
Due to excess production of oil, a pore clogged by dead skin cells, as well as bacteria are caused to the development of pimples. A zit
appears when the bacteria grow in the clogged pore and the oil is unable to escape.
www.iajpr.com
Vol 5, Issue 07, 2015. P. Ravisankar et al. ISSN NO: 2231-6876
Acne –causes
The following are some of the risk factors that may influence for developing acne.
Hormonal changes caused by puberty or pregnancy.
Certain medications such as birth control pills or corticosteroids.
A diet containing huge refined sugars or carbohydrates like bread and chips.
Young people are most at risk for developing acne during puberty. During this time, the body undergoes drastic hormonal
changes. These hormones can trigger oil production, leading to an increased risk of acne. Hormonal acne related to puberty
usually subsides when a teenager reaches adulthood.
Acne lesion implies whiteheads, blackheads, small bumps, nodules and cysts.
Despite acne is fundamentally a normal physiological occurrence, the following prominent conditions may make worse its state.
Fluctuation of hormone levels of women at the time of menstruation.
Disturbing the acne lesions by picking or prodding or hardly press them.
Covering especially total forehead and face with Clothing, hats and sports helmets etc, which badly press the acne lesions.
Better to avoid pizza, greasy and fried foods, and junk foods which are not at all good for overall health, in spite of the fact that
they don‟t create acne or make it worse.
Excessive washing to get rid of dirt from acne can dry and irritate the skin. So essentially gentle wash should be prefferd.
Pressure over the acne to be totally avoided.
In certain patients acne may occur from heredity or can aggravate them.
In some patients, pressure from helmets, chin straps, collars, suspenders, and the like can aggravate acne.
Some medications may cause or worsen acne, which containing iodides, bromides, or oral or injected steroids ,
prednisone, deltasone, orasone, prednisone-M, liquid pred or the steroids. Anyhow many acne cases are not drug related.
In certain specific jobs holders are prone to expose to industrial products may cause of production acne.
Some cosmetics and skin-care products are pore clogging. So water-based products are normally best among lot for those are
suffering from acne.
Rosacea: This condition is characterized by pimples but not comedowns and occurs in the central part of the face showing
2515
redness, flushing, generally occurs to the people above 30 to40 years of age.
Pseudofolliculitis often called razor bumps or razor rash which cause tender bumps those who suffer from acne, if they use razor
for shaving.
Pimples (folliculate) can also occur on other parts of the body namely the abdomen, buttocks, or legs, which are not acne but
inflamed follicles. If they don‟t cure automatically, then oral or external antibiotics are preferred on the medical advice.
Page
www.iajpr.com
Vol 5, Issue 07, 2015. P. Ravisankar et al. ISSN NO: 2231-6876
Acne - treatment
Treating acne requires great patience and proper care and perseverance. Any of the treatments mentioned below may take two
or three months to start working if no side effects such as excessive dryness or allergy is found, it is important to allow ample time to
each regimen or drug to work well before stopping on it and proceed with other methods by the skin specialist [10].
if they experience extreme allergic reactions like feeling faint, breathing problems, throat tightness or swelling of face lips, tongue
or eyes.
www.iajpr.com
Vol 5, Issue 07, 2015. P. Ravisankar et al. ISSN NO: 2231-6876
Turmeric:
Turmeric is usually considered as an effective home remedy for acne. Mix ¼ teaspoon of turmeric powder to two teaspoons
of coconut oil. Mix the mixture well. Apply the mixture on face. Let the mixture sit fifteen minutes. Then wash with cool water.
Tomatoes:
Tomatoes are naturally rich in antioxidants and vitamin-C and A. Tomatoes are used for acne remedy because these are
available at any food store. First slice a small tomato in half. Rub the opened half over areas of the skin where acne is present.
Massage the juice on skin for few seconds is very easy application. Eventually rinse face with warn water. Apply twice a day for
getting decorous results.
Echinacea:
It is used to speed wound healing and prevent colds and flu, infact its antibacterial and anti-inflammatory properties can aid
with acne as well. Utilize Echinacea tea as a daily face wash or Dab it on blemishes with Echinacea tea soaking cotton ball.
Page
www.iajpr.com
Vol 5, Issue 07, 2015. P. Ravisankar et al. ISSN NO: 2231-6876
Sugar scrub:
White or brown sugar aids get rid of the excess skin cells and clogging up acne pores by acting as gently exfoliator. Just
sugar is adding it up with honey, plain water or olive oil and prepares sweet scrub which is used to remove acne woes.
Chamomile:
It helps to reduce the inflammation from acne. In coffee grinder mix the contents of a chamomile tea bag with sufficient
water to form a paste. It is applied to the acne or extract of chamomile tea powder is applied to the acne with cotton ball.
Witch hazel:
Witch hazel can act as an astringent particularly to the naturally drying and shrinking blemishes. Pour witch hazel on to a
cotton ball and efface your face every morning and night.
Lemons:
Lemon act as an exfoliant, disinfectant and skin lightener to decrease the appearance of new pimples forming and scars. Dab
with a cotton ball or cotton swab dipped in a lemon juice on a clean face then rinse with cool water. Lemon juice works as a
disinfectant. It will kill bacteria that cause acne. Lemon juice can also stimulate circulation to the skin which will get essential
nutrients from body to aid fight acne.
Bananas peels:
It contain something substance known as lutein, one of the powerful antioxidant which decreases the swelling and
inflammation, and helps healthy cell growth of the skin of one banana peel is required.
Garlic:
It is one of the natural remedy for acne due to its antibacterial properties. It can be ingest or apply it topically to reduce the
breakouts of acne and prevent them not to reoccur in the future. Garlic is considered to be a good natural remedy for acne because of
2518
its supposed antibacterial properties. 2-3 cloves of garlic and fresh drinking water are needed.
Oatmeal:
Soaked or cooked oats to be used in the face mask, which can reduce the inflammation and redness with breakouts. One
serving of oatmeal, Water and two tablespoons honey is necessary.
Page
www.iajpr.com
Vol 5, Issue 07, 2015. P. Ravisankar et al. ISSN NO: 2231-6876
White Sugar:
It helps to get rid of the excess skin cells clogging up pores. Mix it with honey, olive oil, and fresh water and scrub to clear
acne woes.
Raw potato:
Take raw potato and rub the pulp and juice on the face for a few minutes let it dry for 15-30 minutes, and then rinse off
completely with lukewarm water. potatoes consists of potassium, sulphur, phosphorus, and chloride aid to relieve from trouble
shooting blemishes and help to grow new cells.
Mint:
It has menthol content, which works as a natural anti-inflammatory and pain killer but it cannot cure acne yet it acts as
helping agent to lessen the redness spot on the skin.
Fuller’searth:
Fuller‟s earth (multani mitti) is good for greasy and ache-prone skin because it absorbs excess of oil and unclogs the pores.
Just mix equal parts of fuller‟s earth in rose or sandalwood powder. Use this mud pack to your face. Just wash up it dries up. This
process can be repeated once a week.
Azelaic acid:
This is naturally occurring acid is found in whole grain cereals and animal products. 20 percent azelaic acid cream seems to
be as effective as many other conventional acne treatments when used twice daily for 4 weeks. This can be sometimes used with
erythromycin. Azelaic acid has antibacterial properties.
Bovine cartilage:
Creams containing five percent bovine cartilage, applied to the affected skin twice a day, may be effective in reducing acne.
Zinc:
Zinc in lotions and creams may lessen acne breakouts.
Brewer's yeast:
A specific strain of brewer‟s yeast, called CBS 5926, seems to aid reduce acne. Brewer's yeast is the only item in this list
that's taken orally. It may cause flatulence.
diet like Zinc, Vitamins A, C & E may assist in the acne treatment.
acne. (Good rule: The urine color should be clear you have had enough water, suppose if it is yellowish, aim to have more water in
your diet).
www.iajpr.com
Vol 5, Issue 07, 2015. P. Ravisankar et al. ISSN NO: 2231-6876
Good fats:
Fatty foods are bad for acne. Good fats that aid fight acne. Omea-3 fattly acids aids keep the skin flexible and drain sebum
out the pores. This will reduce the oil that is related with acne. For goods fats nuts, avocados, cold water fish.
Proteins:
The body utilizes the amino acids from protein to construct collagen. This nutrient helps keep the skin healthy and hydrated.
Good sources of proteins are poultry, dairy products, eggs, beans seafood and soy.
Vitamin A:
Vitamin A helps to reduce the oil your skin products. Best sources are carrots, sweet potato and dark green vegetables.
Artificial sugars:
Generally sugar stimulates levels of insulin in blood which can increase the amount of oil your skin products. Intake of soft
drinks and junk foods to reduce the amount of sugar in your system.
A hint found on many websites is that toothpaste can dry up individual spots. While toothpaste does have antibacterial
substances, it also contains substances that can irritate and damage your skin so it may not be preferable. Apply a minute amount of
white toothpaste on the affected area prior to going to bed. The toothpaste will decrease the swelling and dry out the acne. Within a
day or two considerable improvements is seen. Acne is not caused by dirt, poor hygiene, not washing face etc. Too much scrubbing or
cleansing with harsh soaps or chemicals can actually irritate your skin and make the acne brings to worst condition. Stress can affect
hormones, and thus promote acne. Yet, perfect acne treatment regime will surpass stress to some extent anytime. After treatment with
banana peels or over the counter creams application of a moisturizer can help to balance the treated skin.
www.iajpr.com
Vol 5, Issue 07, 2015. P. Ravisankar et al. ISSN NO: 2231-6876
CONCLUSION
Despite recent scientific investigations, researchers are still not able to arrive at correct conclusions scientifically about acnes
on the various parts of the body. But the proper option is to abandon all things that may cause or worsen the acne by keeping face and
body skin clean every day. Diet, lifestyle and herbs can be an important part of natural remedies. Born of Acne cannot be cured. After
its emergeit can be controlled with treatment. The main goal of acne treatment is to decrease or clear up the spots through treatments
or skin care to inhibit sebum production, bacterial growth, shedding of skin cells and unclogging pores. Acne comes and goes,
between the age of twelve and twenty-three, but some people develop severe acnes because of production of higher level of androgens
in their systems but men are more sufferers from acne than women. More than 40 percent of all teens develop acne if severe require
medical attention yet most cases are usually solved without treatment. Anyhow, modern medical treatment and over-the-counter
products cater to the need of people suffering from acne without feeling pain. In women, acne is associated with their fertility cycle
and change of hormone levels. Stress doesn't cause acne, but stress can make it worse. Neck acne is a difficult proposition as the neck
is one of the most sensitive areas of the body and requires proper moisturizing and care. Further investigations and research is going
on to find out the root for the cause of Acne.
2521
Page
www.iajpr.com
Vol 5, Issue 07, 2015. P. Ravisankar et al. ISSN NO: 2231-6876
REFERENCES
1. Strauss JS., Krowchuk DP., Leyden JJ., et al, Guidelines of care for acne vulgaris management, American Academy of
Dermatology/American Academy of Dermatology Association, J Am Acad Dermatol, 2007; 56:4: 651-663.
2. Wolff K., Fitzpatrick TB., Johnson RA., eds, Acne vulgaris (common acne) and cystic acne, In Fitzpatrick‟s Color Atlas and
Synopsis of Clinical Dermatology,6th ed. New York, NY: McGraw-Hill: 2009: 2-6.
3. White GM., Recent findings in the epidemiologic evidence, classification, and subtypes of acne vulgaris, J Am Acad Dermatol,
1998; 39:2 pt 3: S34-S37.
4. Layton AM., Stainforth JM., Cunliffe WJ, Ten years‟ experience of oral isotretinoin for the treatment of acne vulgaris, J Dermatol
Treat, 1993; 4:2: S2-S5.
5. Amichai B., Shemer A., Grunwald MH, Low-dose isotretinoin in the treatment of acne vulgaris, J Am Acad Dermatol,2006; 54:4:
644-646.
6. James WD, Clinical practice. Acne, N Engl J Med, 2005; 352:14: 1463- 1472.
7. Magin P., Pond D., Smith W., Watson A, A systematic review of the evidence for „myths and misconceptions‟ in acne
management: diet, face washing and sunlight, FamPract, 2005; 22:1: 62-70.
8. Son BK, Yun Y., Choi IH, Efficacy of ah shi point acupuncture on acne vulgaris, Acupunct Med, 2010; 28:3: 126-129.
9. Enshaieh S., Jooya A., Siadat AH., Iraji F, The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a
randomized, double-blind placebo controlled study, Indian J Dermatol Venereol Leprol, 2007; 73:1: 22-25.
10. Hamilton FL., Car J., Lyons C., Car M., Layton A., Majeed A, Laser and other light therapies for the treatment of acne vulgaris:
systematic review, Br J Dermatol, 2009; 160:6: 1273-1285.
11. Katsambas AD., Dessinioti C., Hormonal therapy for acne: why not as first line therapy? Facts and controversies, Clin Dermatol,
2010; 28:1: 17-23.
12. Arowojolu AO., Gallo MF., Lopez LM., Grimes DA., Garner Recombined oral contraceptive pills for treatment of acne,
Cochrane Database Syst Rev, 2009; 3: CD004425.
13. Thielitz A., Abdel-Naser MB., Fluhr JW., Zouboulis CC., Gollnick H, Topical retinoids in acne-an evidence-based overview, J
Dtsch Dermatol Ges, 2008; 6:12: 1023-1031.
14. Thiboutot D., Gollnick H., Bettoli V., et al, New insights into the management of acne: an update from the Global Alliance to
Improve Outcomes in Acne group, J Am Acad Dermatol, 2009; 60:5: S1-S50.
15. Simonart T., Dramaix M., De Maertelaer V, Efficacy of Tetracyclines in the treatment of acne vulgaris: a review, Br J Dermatol,
2008; 158:2: 208-216.
16. Thiboutot D., Zaenglein A., Weiss J., Webster G., Calvarese B., Chen D, An aqueous gel fixed combination of Clindamycin
phosphate 1.2 % and benzoyl peroxide 2.5% for the once-daily treatment of moderate to severe acne vulgaris: assessment of
efficacy and safety in 2813 patients Am Acad Dermatol, 2008; 59:5: 792-800.
54878478451150722
2522
Page
www.iajpr.com