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T3 and T4 in hypothyroidism
a. both increased
1. The proper order in capillary puncture: b. both decreased
a. EDTA-serum-smear c. T3 increased, T4 decreased
b. smear-serum-EDTA d. T4 decreased, T3 increased
c. serum-EDTA-smear
d. smear-EDTA-serum 16. Triglyceride level in hypothyroidism
a. increased
2. The proper order when dispensing a syringe into vacutainer tubes: b. decreased
a. Black-Lavender-Red-Gray c. variable
b. Black-Lavender-Gray-Red d. cannot be determined
c. Red-Black-Lavender-Gray
d. Black-Red-Lavender-Gray 17. Triglyceride level in hyperthyroidism
a. increased
3. Age group associated with moderate risk of 240 mg/dL total b. decreased
cholesterol and high risk of 260 mg/dL. c. variable
a. 2-19 years old d. cannot be determined
b. 20-29 years old
c. 30-39 years old 18. Increase in AMS is indicative of what condition?
d. 40 years old and above a. acute gastritis
b. appendicitis
4. Measures liver function in transplant patients: c. muscle dystrophy
a. coagulation studies d. acute pancreatitis
b. bilirubin
c. AST/ALT 19. Uric acid measurement affected by turbidity
d. AOTA a. Colorimetric, endpoint
b. Colorimetric, kinetic
5. Disinfection of vacutainer tubes is done using: c. Enzymatic, kinetic
a. autoclave d. Enzymatic, endpoint
b. autoclave, ethylene oxide, gamma radiation
c. gamma radiation 20. Creatinine measurement which is simple and nonspecific
d. ethylene oxide a. Colorimetric, endpoint
b. Colorimetric, kinetic
6. Measurement that is included in identifying risk for CHD c. Enzymatic, kinetic
a. Cholesterol d. Enzymatic, endpoint
b. HDL
c. TAG 21. Conversion factor for thyroxine:
d. Protein a. 9.9
b. 10.9
7. GGT belongs to what class according to type of reaction it c. 11.9
catalyzes? d. 12.9
a. Oxidoreductase
b. Transferase 22. A consent from the attending physician is needed when this
c. Hydrolase venipuncture site is used.
d. Ligase a. antecubital
b. back of hands
8. LDH is considered a/an: c. foot
a. Oxidoreductase d. below IV line
b. Transferase
c. Hydrolase 23. A measure of precision
d. Ligase a. Mean
b. Mode
9. CK, ALT and AST all belongs to what class of enzymes according to c. Standard deviation
type of reaction? d. Coefficient of variation
a. Oxidoreductase
b. Transferase CLINICAL CHEMISTRY PART II
c. Hydrolase
d. Ligase 1. Independent variable is related to:
a. Y-axis
10. It has a moderate specificity for liver, skeletal and cardiac muscle. b. Vertical axis
a. LDH c. Ordinate
b. ALT d. Abscissa
c. AST
d. Aldolase 2. Vertical axis is the same with:
a. X-axis
11. Primary organ involved in the production of estrogen. b. Abscissa
a. Adrenal glands c. Independent Variable
b. Placenta d. Y-axis
c. Ovary
d. Pituitary gland 3. In hypothyroidism, the patient’s triglyceride level:
a. Increases
12. Associated with female reproductive hormones: b. Decreases
a. Infertility c. Normal
b. polycystic ovarian syndrome d. No change
c. hirsutism
d. AOTA 4. In hyperthyroidism, the patient’s triglyceride level:
a. Increases
13. The following pose a mechanical hazard: b. Decreases
I. centrifuge II. refrigerator c. Normal
III. gas cylinder d. No change
a. I and II
b. II and III 5. A drunk driver will be considered as legally intoxicated with
c. I and III alcohol if its %w/v in body is:
d. II only a. 0.05
b. 0.10
14. Considered as minor lipoproteins c. 0.15
a. LpX and HDL d. 0.20
b. HDL and LDL
c. VLDL and chylomicrons
d. IDL and Lp(a)
6. Manifesting impaired consciousness, an individual 20. A patient with Gilbert syndrome has a problem with bilirubin:
intoxicated with alcohol has its %w/v in the body of: a. Excretion
a. 0.09-0.25 b. Conjugation
b. 0.18-0.30 c. Transport
c. 0.27-0.40 d. Inhibitor
d. 0.35-0.50
21. Increase in enzyme concentration in the blood is best
7. This approach to the assay for urea nitrogen is inexpensive indicates:
and lacks specificity. a. Cellular injury and organ damage
a. Diacetyl monoxime b. Specific disease
b. Ammonia formation c. Excessive medication
c. Caraway d. Damage in storage areas
d. Kinetic
22. All but one are example of an oxidoreductase enzyme:
8. The most simple method for creatinine determination but is a. G-6-PD
nonspecific is: b. LDH
a. Enzymatic c. CHS
b. Colorimetric endpoint d. Cytochrome oxidase
c. Colorimetric kinetic
d. Red tautomer 23. Phenobarbital can be categorized as an
_____________________ drug.
9. In SI units, a value of 2.1 mg/dL of bilirubin is equivalent to: a. Antihistamine
a. 35.91 mmol/L b. Anticonvulsant
b. 35.91 µmol/L c. Antipyretic
c. 36.54 mmol/L d. Antispasmic
d. 36.54 µmol/L
24. For every 1°C increase in body temperature: pH decreases
10. What is the conversion factor for thyroxine? by _____; pO2 decreases by ______; and pCO2 increases by
a. 12.2 ______.
b. 12.4 a. 0.015; 7; 3
c. 12.6 b. 0.015; 3; 7
d. 12.8 c. 0.010; 7; 3
d. 0.010; 3; 7
11. For venipuncture, the angle in the procedure is:
a. 15° 25. Hazard number 2 indicates:
b. 20° a. Extreme
c. 25° b. Slightly
d. 30° c. Moderate
d. Severe
12. Which among the photodetectors below is the most
sensitive? 26. What age group is usually affected with serum cholesterol of
a. Photodiode high risk > 260mg/dL and moderate risk > 240 mg/dL?
b. Photovoltaic cell a. 2 – 19 years old
c. Photomultiplier tube b. 20-29 years old
d. Photobarrier c. 30-39 years old
d. 40 and above
13. This machine uses a specialized light source wherein the
analyte of interest is coated within the hollow-cathode lamp. 27. In order to attain a perfect Gaussian curve, which of the
a. Nephelometry following is true?
b. Flame Emission Photometry a. Mean>Median>Mode
c. Atomic Absorption Spectrometry b. Mean<Median<Mode
d. Fluorometry c. Mean=Median=Mode
d. Mean>Median<Mode
14. The most basic pipette and is commonly used in the
laboraties. 28. Which of the following is true about Fahey and McKelvey
a. Automatic pipette method?
b. Glass pipette a. Kinetic method
c. Air displacement pipette b. Measured after 18 hours
d. Positive displacement pipette c. Diameter = log of concentration
d. All of the above
15. This type of chemical is used for human consumption and
drug manufacturing. 29. In patient undergoing liver transplant, which of the test
a. Analytical grade requires a normal result?
b. Chemically pure a. PT and Albumin
c. USP and NF b. Bilirubin
d. Commercial grade c. Enzymes
d. All of the above
16. Which among the assays for cholesterol determination has
colorimetry as its principle? 30. In hypothyroidism, the T3 uptake test is ________________.
a. Salkowski a. Increased
b. Abell Kendal b. Decreased
c. Liebermann Burchardt c. Normal
d. Van Handel Zilversmith d. No change
17. Minor lipoproteins 31. Which assay for lactate dehydrogenase uses lactate as its
a. CM and VLDL substrate then converting it to pyruvate?
b. LDL and HDL a. Wacker
c. IDL and Lp(a) b. Wrobleuski Ladue
d. Lp(a) and LpX c. Tanzer-Gilbarg
d. Oliver-Rosalki
18. All but one are found in the alpha 2 region in serum protein
electrophoresis.
a. Fibrinogen
b. Haptoglobin
c. Ceruloplasmin
d. α-2 MAC
18. This bacteria is usually the associated with the UTI in young
female
a. S. saprophyticus
b. S. epidermidis
c. E. coli
d. L. acidophilus
1. In routine urinalysis, how do you report cystine crystals? 1. The reagent used in APT Test is
a. rare, few, moderate, many per HPF a. NaOH
b. rare, few, moderate, many per LPF b. HCl
c. average number per HPF c. H2SO4
d. present or absent d. KOH
2. What is the principle of the automated strip readers? 2. This RBC count indicates blunt trauma in peritoneal lavage.
a. Reflectance photometry a. 1 000
b. Flow cytometry b. 10 000
c. Light scattering c. 100 000
d. Fluorometry d. 1 000 000
5. What analyte/s is/are reported in Ehrlich units? 5. Manner of reporting for RTE
a. urobilin, urobilinogen a. #/ LPF
b. urobilinogen b. #/ HPF
c. bilirubin c. Few, moderate, many
d. bilirubin, urobilin, urobilinogen d. 1+, 2+, 3+, 4+
6. Convert 40 Ehrlich units to mg/dL. 6. During microscopy, casts are usually seen
a. 0.4 a. Center of the coverslip
b. 4 b. Side of the coverslip
c. 40 c. Near the edge of the coverslip
d. 400 d. Outside of the coverslip
7. Fire caused by electrical equipments 7. What urine color is associated with the use of drug for UTI
a. Class A fire treatment?
b. Class B fire a. Green
c. Class C fire b. Orange
d. Class D fire c. Black
d. Red
8. It is used to extinguish Class A fire.
a. Halon 8. The normal color of gastric fluid is
b. Dry chemical a. Colorless
c. Water b. Green
d. Carbon dioxide c. White
d. Gray
9. The amniotic fluid is yellow in color. Using the spectrophotometer, it
has a peak absorbance at 450 nm. What substance is indicated? 9. What is the size of the sperm’s acrosomal cap?
a. phospholipid a. Half of the head
b. hemoglobin b. 2/3 of the head
c. bilirubin c. ¼ of the head
d. carotene d. 1/3 of the head
10. In a poorly equipped laboratory, this is used to identify rape cases: 10. Spinal fluid tube for hematology is usually stored in
a. zinc a. Room temperature
b. fructose b. Frozen temperature
c. ACP c. Incubator
d. citric acid d. Water bath
12. Most characteristic of pyelonephritis: 12. This is known as the filtering unit of the urinary system
a. RBC cast a. Proximal convoluted tubule
b. RBCs b. Distal convoluted tubule
c. WBC cast c. Glomerulus
d. OFB d. Podocyte
13. Which of the following produces an alkaline urine? 13. Nomarski microscope
a. meat a. Brightfield microscope
b. vegetable b. Interference contrast microscope
c. cranberry juice c. Darkfield microscope
d. dehydration d. Fluorescent microscope
14. In the acronym RACE, A stands for
14. What is the normal color of gastric fluid? a. Alarm
a. light yellow b. Attach
b. pale gray c. Aline
c. amber d. Artificial
d. colorless with a brown tinge
15. The urine volume of a patient with polyuria usually is
Reporting! Reporting! Reporting! a. 1 500 – 2 000 mL
b. >2 000 mL
c. >3 000 mL
d. >4 000 mL
16. When trying to repair a broken electrical equipment, the first 30. A brown semen indicates the presence of
thing to do is to a. Bile
a. Unplug the equipment b. Cholesterol
b. Turn off the circuit breaker c. Blood
c. Always use gloves d. Bilirubin
d. Read the manual
31. Renal calculi is usually formed in the
17. In reporting the urine clarity, blurred print is reported as a. Bladder
a. Hazy b. Ureter
b. Cloudy c. Calyces and pelvis of kidney
c. Turbid d. All of the above
d. Milky
32. Ammonium precipitation test is also known as
18. Which of the following is a component of acetest tablet? a. Florence Test
a. Copper sulfate b. Blondheim Test
b. Sodium hydroxide c. Turbidity Test
c. Lactose d. Liley Test
d. Sodium carbonate
33. During a pregnancy test, you observed a faint line along the
19. Which of the following is not a component of clinitest tablet? test area in the kit. What will you do?
a. Copper sulfate a. Report as positive
b. Sodium hydroxide b. Report as negative
c. Lactose c. Indeterminate
d. Sodium carbonate d. Repeat test
20. A result of 2.5 Ehrlich unit is also equivalent to 34. Bence Jones Protein is characterized by its unique ability to
a. 2.5 mg/dL coagulate in ______________ and dissolve
b. 5.0 mg/dL _________________.
c. 7.5 mg/dL a. 30-50°C : 80-100°C
d. 10 mg/dL b. 40-50°C : 80-90°C
c. 50-60°C : 90-100°C
21. Crystal which is characterized as yellow brown needles is d. 40-50°C : 80-100°C
a. Cysteine
b. Ampicillin
c. Sulfonamide
d. Tyrosine
22. What zone in Liley’s graph indicates that the fetus requires
close monitoring?
a. Zone I
b. Zone II
c. Zone III
d. Zone IV
6. 3rd layer in the spun hematocrit 21. In light scattering, what does forward scatter depict?
a. buffy coat a. cell granularity
b. fatty layer b. cell size
c. plasma c. cell lobularity
d. packed red cell d. cell complexity
7. Present in neutrophils but not in monocytes 22. Blue-gray granules within the cytoplasm of neutrophils, usually
a. acid phosphatase found during infections.
b. muramidase a. May-Hegglin bodies
c. alkaline phosphatase b. Dohle bodies
d. peroxidase c. Russell bodies
d. Lysosomes
8. Causes of positive errors in automation
a. Bubbles 23. What is the corrected WBC count when a medical technologist
b. Extraneous pulses counted 1.2 x109 WBCs per liter, and seen 50 nucleated RBCs.
c. Aperture plugs a. 0.6 x 109 WBCs per liter
d. AOTA b. 0.8 x 109 WBCs per liter
c. 1.0 x 109 WBCs per liter
9. Causes of negative errors in automation d. 1.2 x 109 WBCs per liter
a. Excessive lysing
b. Aperture plugs 24. Needs contact with negatively charged surface for activation
c. Extraneous pulses a. FXII and FXI
d. Bubbles b. HMWK
c. PK
10. Stem cell marker d. AOTA
a. CD21
b. CD34 25. Also known as keratocytes.
c. CD45 a. Leptocytes
d. CD56 b. Drepanocytes
c. Helmet cells
11. The absence of Philadelphia chromosome in CML indicates: d. Mexican hat cells
a. Better prognosis
b. Rapid progression of disease 26. NOT a disorder of the macrophage/monocyte:
c. No relationship with CML a. Gaucher c. Niemann-Pick
d. AOTA b. Pelger-Huet d. Alder-Reilly
12. Using the Rule of Three. Find the Hemoglobin (in g/L) and the HEMATOLOGY PART II
Hematocrit (in decimal) using the RBC count 4.2 x 109/L, respectively.
a. 12.5 and 38 1. All of the following can cause a false positive result in
b. 12.5 and 0.38 automated hematological analyzers except:
c. 125 and 38 a. Bubbles
d. 125 and 0.38 b. Extraneous impulses
c. Aperture plugs
13. Screening test for sickle cells d. Improper setting of aperture current
a. Dithionite test
b. Heat denaturation test 2. Improper settling of aperture current can cause which of the
c. Ham’s test following:
d. Sucrose hemolysis test a. False positive
b. False negative
14. Leukocytosis is a term used for a WBC count greater than _____ x c. Either false positive or negative
109/L d. None of the above
a. 30 c. 20
b. 11 d. 25 3. Which of the following is the correct order of draw for
anticoagulants in collection tubes using syringe method?
15. If the count of lymphocytes is greater than the neutrophils in adult a. Citrate, heparin, EDTA, oxalate, none additive
WBC count, do a: b. Heparin, EDTA, oxalate, none additive, citrate
a. 50-differential c. EDTA, oxalate, none additive, citrate, heparin
b. 200-differential d. None additive, citrate, heparin, EDTA, oxalate
c. 250-differential
d. 500-differential
4. Which of the following is the correct order of draw in capillary 17. Normocytic and normochromic anemia is usually seen in
blood collection? patients with _______________________.
a. Blood gases, red top, lavender top, other additive a. Iron deficiency anemia
tube, slide b. Aplastic anemia
b. Blood gases, slide, lavender top, other additive c. Thalassemia
tube, red top d. Anemia of chronic disease
c. Slide, lavender top, other additive tube, red top,
blood gases 18. A reddish or pinkish PBS indicates
d. Lavender top, other additive tube, red top, blood a. Low pH of buffer
gases, slide b. Excessive washing
c. Long contact with acidic stain
5. Euglobin clot lysis is a _____________________ test. d. All of the above
a. Definitive
b. Screening 19. A dark bluish or purplish PBS indicates
c. Confirmatory e. High pH of buffer
d. Substitute f. Improper washing
g. Long contact with basic stain
6. Drepanocytes: 10-15/ HPF h. All of the above
a. 1+
b. 2+ 20. Which of the instrument used in coagulation has
c. 3+ electromechanical principle?
d. + a. Coag-a-mate
b. Siemens
7. The positive result for Sodium dithionite test is c. Advia
____________________. d. Fibrometer
a. Color change
b. Turbidity 21. Deficiency of this coagulation factor usually causes a
c. Solubility disease prominent in Ashkenazi Jews.
d. Coagulation a. VIII
b. IX
8. This is also known as the Common Acute Lymphoblastic c. X
Leukemia Antigen d. XI
a. CD 10
b. CD 15
c. CD 20
d. CD 25
11. This cell is the youngest among the line of WBC which can
normally be seen in PBS.
a. Band cell
b. Metamyelocyte
c. Stab cell
d. Myelocyte
16. Hb S
a. Valine replaces glutamic acid in the 6th position
b. Lysine replaces glutamic acid in the 6th position
c. Valine replaces glutamic acid in the 26th position
d. Lysine replaces glutamic acid in the 26th position
IMMUNOLOGY/SEROLOGY & BLOOD BANKING 15. After collection, you noticed that the tubing of the blood bag is
leaking. What should you do?
1. Antigen determinant: a. Discard the unit.
a. Epitope b. Immediately separate the components into the satellite
b. Paratope bags, all components may be used.
c. Hinge region c. Immediately separate the components into the satellite
d. Fc region bags, only red cells may be used.
d. Immediately separate the components into the satellite
2. Part of antibody which binds foreign substance: bags, only plasma may be used.
a. Epitope
b. Paratope 16. Determine the blood type of the following result:
c. Hinge region A cells: +++ B cells: 0 H cells: 0
d. Fc region a. “AB”
b. “A”
3. This is where the antibody binds to the antigen. c. “B”
a. Carrier d. “O”
b. Schlepper
c. Deteminant 17. Permanently deferred:
d. Fab region a. use of human-derived GH
b. diabetic patient using injected insulin
4. Annie had a partner who was diagnosed of HIV. How long will Annie c. past history of drug abuse
wait before she can donate? d. AOTA
a. 2 to 4 weeks
b. 3 to 6 months 18. Tumor marker for bladder cancer
c. 6 to 12 months a. CA 27-29
d. 1 to 2 years b. her2/neu
c. calcitonin
5. PCR d. nuclear matrix protein
a. serological
b. molecular 19. Immediate hypersensitivity
c. cellular a. Type I
d. chemical b. Type II
c. Type III
6. RFLP d. Type IV
a. serological
b. molecular 20. Advantage of packing WB immediately just before infusion:
c. cellular a. decrease sodium, phosphate
d. chemical b. decrease sodium, lactic acid
c. decrease potassium, phosphate
7. A disease which is associated with HLA-B27 d. decrease potassium, lactic acid
a. Rheumatoid arthritis
b. Ankyloarthritis 21. Pentameric Ig:
c. Diabetes mellitus a. IgG
d. Multiple sclerosis b. IgM
c. IgA
8. Which among the following disease is associated with anti-dsDNA d. IgD
and anti-phospholipid antibodies?
a. SLE 22. Immunoglobulin found in tears
b. RA a. IgG
c. MM b. IgM
d. MS c. IgA
d. IgD
9. First documented human transfusion
a. Queen Elizabeth I 23. Fluorescent label attached to an antibody against the antigen-
b. Prince Charles II antibody complex
c. Pope Innocent VII a. Indirect
d. King Arthur V b. Direct
c. Inhibition
10. Sample used in DAT: d. NOTA
a. heparin
b. EDTA 24. Indicates active infection and infectious state:
c. citrate a. HBs Ag
d. oxalate b. HBe Ag
c. anti-HBc
11. Fluoroscent stained specimens are visualized using what type of d. anti-HBe
microscope?
a. brightfield 25. NOT included in screening of infectious blood-borne pathogens
b. darkfield a. hepatitis A
c. phase contrast b. hepatitis B
d. polarizing c. syphilis
d. malaria
12. What blood component is most useful in patients with a history of
febrile reactions? 26. This blood-borne pathogen is not screened for WB donation, but
a. irradiated screened when doing component preparation.
b. washed a. CMV
c. leukoreduced b. HTLV I
d. pheresis c. HTLV II
d. HIV
13. Used for irradiation of blood components
a. Lithium 27. It is characterized by the presence of anti-smooth muscle antibody
b. Rubidium a. biliary obstruction
c. Cesium b. chronic active hepatitis
d. Radium c. multiple sclerosis
d. pemphigoid
14. A medical technologist working in Blood Bank noticed a clot
floating on top of the plasma of a stored whole blood. What should the 28. A patient experienced episodes of hemolytic anemia. Testing for
technologist do? the presence of antibody yielded positive, and reacted with almost all
a. Discard the whole unit. cells. What antibody is most likely?
b. Immediately remove and discard the plasma; issue a. anti-D
remaining packed red cell. b. anti-K
c. Use a filter to remove clot; issue unit afterwards. c. anti-P
d. Issue whole blood. d. anti-I
29. Confirmatory test for HIV 12. What collection tube is used in obtaining specimen for
a. EIA antibody screening?
b. RIBA a. Lavender
c. Western blot b. Green
d. Southern blot c. Pink
d. Red
30. Part of the light chains of MHC class I.
a. acid-1-glycoprotein 13. The collection tube used in DAT is
b. beta-2-microglobulin a. Lavender
c. serum amyloid A b. Green
d. alpha-2-macroglobulin c. Pink
d. Red
IMMUNOLOGY/SEROLOGY & BLOOD BANKING PART II
14. CD8
1. The first recorded blood transfusion in history is between this a. Helper cell
head of state and three donor. b. Cytotoxic cell
a. Pope John Paul I c. Null cell
b. Pope Peter XV d. Natural killer cell
c. Pope Pius XII
d. Pope Innocent XVI 15. This blood component is described as young RBCs and is
2. This is known as the marker Hepatitis B infectivity. usually used in patients with Thalassemia.
a. HBsAg a. Neocytes
b. HBeAg b. Kiddocytes
c. HBcAg c. Young RBC
d. None of the above d. Reticulocytes
3. Antigenic determinant 16. This technique is used to collect blood sample from the
a. Paratope umbilical cord.
b. Epitope a. Cordocentesis
c. Hepatope b. PUBS
d. Kininogen c. Both
d. Neither A nor B
4. Which of the following is the most common
immunodeficiency?
a. Severe combined immunodeficiency
b. Selective IgA deficiency
c. X-linked agammaglobulinemia
d. Common variable immunodeficiency
8. Aka dealcoholization
a. dehydration
b. clearing
c. infiltration
d. decalcification
9. X axis
a. vertical axis and independent variable
b. vertical axis and dependent variable
c. horizontal axis and independent variable
d. horizontal axis and dependent variable