Prof. P. R. Vavia Resume

Prof. P.R.
Vavia
B.Pharm., M.Pharm., Ph.D. (Tech)
Professor of Pharmaceutics
A-257, Center for Novel Drug Delivery Systems,
Department of Pharmaceutical Science and Technology,
Institute of chemical technology,
[University under Section-3 of UGC ACT (1956)]
Nathalal Parekh Marg, Matunga, Mumbai – 400 019
E-mail: pr.vavia@ictmumbai.org
Tel. No. 91-22-2414 5616 (Extn.- 2220)
Fax. No. 91-22-2414 5614
Degrees with name of university/institute:
B.Pharm.
University / Institute: University of Mumbai
Year : 1985
M.Pharm.
Field(s) : Advance Pharmaceutics
Title of Thesis : Studies on Percutaneous
Absorption of Ketoprofen
Year : 1987
Ph.D.(Tech.)
Field(s) : Advance Pharmaceutics
Title of Thesis : Development and Evaluation of
Radioimmunoassay for
Therapeutics Monitoring of
Theophylline
Year : 1991
Research Interest:
 Cyclodextrins based drug delivery systems

 Nanosponge based drug delivery systems
 Bioencapsultion
 Multiparticulte drug delivery system
 Transdermal drug delivery systems
 Protein and peptide drug delivery system
 Lipid based colloidal formulations
 Polymer synthesis for drug delivery
 Modified release films
 Liposome based Drug Delivery Systems
 Melt Extrusion Technology
 Oral liquid dosage forms
 Techniques in solubilization
Brief statement on current research activities:
Keeping in mind, the constraints to efficient delivery of potential drug candidates
and ample opportunities associated with design of non-infringing drug formulations as
well as value added generic drug development sector, Prof. P.R. Vavia and his research
group is currently involved in fundamental as well as industrial research.
Research work based on cyclodextrin and their derivatives, nanosponge based
drug delivery systems, Bioencapsulation of poorly soluble actives, modified release
multiparticulate drug delivery systems, application of particle engineering strategies,
transdermal drug delivery systems, techniques in solubilisation of poorly water soluble
drugs, microemulsions, nanosuspensions, protein and peptide based drug delivery
systems, synthesis and application of novel polymers and excipients is going on with
expected outcomes of industrial applicability and scalability.
Development and validation of analytical methods, In-vivo studies of developed
formulations and preparation of CTD as per regulatory requirements of international
markets has given equal importance to meet the international standards.
Courses taught:
B.Pharm, B.Tech Pharma, M.Pharm (Pharmaceutics, Advanced pharmaceutics,

Pharmaceutical Analysis, Biopharmaceutics, Industrial Pharmacy)
Awards, Honours and Accolades:

 Research Fellow of Human Resources Development
 Junior Research Fellow of Department of Atomic Energy
 Senior Research Fellow of Department of Atomic Energy
 Fellow, Indian Pharmaceutical Association, 2003 awarded at Indian

Pharmaceutical Congress, Chennai, Dec. 21st -23rd, 2003
 Johnson and Johnson, USA, Research Award (US$ 20,000), 2001.

 U.P.Government National Award for an outstanding work done in the area of
interaction with Industries, 2005.
 Maharashtra Fellow for Medical Sciences, 2006.
 Best Teacher’s Award, University Institute of Chemical Technology at

undergraduate level, 2007.
 Distinguish Teacher Award, Maharashtra Pharmacy Association, 2009.
 “Incentives to Meritorious Teachers”, Dr. K. H. Gharda Reward, Board of

Governers, Institute of Chemical Technology, 2009.
 Best Teacher’s Award, University Institute of Chemical Technology at

undergraduate level, 2010.
Professional Activities:
 Life member, Indian Pharmaceutical Association
 President, Indian Pharmaceutical Association (2002-2004) (Maharashtra State
Branch)
 Member, Association of Pharmacy Teachers of India (APTI)
 Member, Royal Pharmaceutical Society of Great Britan (Hon. Membership)
 Inspector appointed by Pharmacy Council of India for Inspection of Institutions
 Inspector appointed by AICTE for Inspection of Institution
 Member, Editorial board of Indian Journal of Pharmaceutical sciences
 Expert Member, DSIR for inspection of industrial R & D facility
 Nominee of Vice-chancellor for appointment of teachers of Mumbai University
 Member, International Advisory board, Asian Oceanic Cyclodextrin League
 Scientific Convener, Indian Pharmaceutical Congress Association, 2006-2009.
 Member of Italian Cyclodextrin League.
 Convener, 5th Young Innovative Choice Competition (YICC) and Young Research
Competition (YRC), 2010-2011
 Reviewer of
 AAPS Pharm Sci-Tech
 International Journal of Pharmaceutics
 Nanomedicine: Nanotechnology, Biology, and Medicine
 Indian Journal Pharmaceutical Sciences
 Pharmaceutical research
 Journal of pharmacy and Pharmacology
 AIChE Journal
 Journal of Controlled Release
Industrial interaction
(a) Past
 Novartis India Ltd.
 Panacea Biotec.
 Unichem Laboratories Ltd.
 Bayer India Ltd.
 Glenmark Pharmaceuticals Ltd.
 Cipla Ltd.
 Burroghs Wellcome.
 Jhonson & Jhonson Ltd.
 Medicap Ltd. (Bangkok, Thailand.)
 Atlantic Pharma
 Bajaj Healthcare Pvt. Ltd.
 Indoco Ltd.
 Themis Laboratories Ltd.
 Choice Laboratories Ltd.
 Goldshield Inc. (UK)
 Oman Pharmaceuticals, Oman.
 Dr. Reddys Lab.
 Bayer India Ltd.
 Macleods Laboratories Ltd.
 Colorcon Asia Pacific
 Rusan Pharma Ltd.
 BASF
(b) Current
 Kusum Health Care

 Nippon synthetic chemical industries Ltd
 Raptim
 Uni-Sankyo Ltd.
 Cyril Healthcare Pvt Ltd.
Master students Guided: 38
Ph.D Students Guided: 29
Current research students:

Masters Students: 06
Ph.D Tech. Students: 18
Sponsored Projects:
(a) Previous:
1. Sponsor :Franco India Pharmaceuticals Limited
Title :Design and evaluation of diclofenac gel
Total Amount : Rs. 10,000/-
2. Sponsor : Cipla Limited
Title :Development and evaluation of topical formulations.
Total Amount : Rs. 1.5 lakhs
3. Sponsor :Johnson & Johnson Limited
Title :Evaluation of anti-fungal creams and development of validated analytical

method
4. Sponsor : Chin Chem.
Title : Design of sustained release isosorbide dinitrate pellet formulation
Title : Development and evaluation of acyclovir liposomal gel formulation
6. Sponsor :UDCT Golden Jubilee Research Fund
Title : Synthesis and evaluation of terpolymer for transdermal therapeutic system
7. Sponsor : Unichem Laboratories
Title : Development of Novel drug delivery system
Total Amount : Rs. 1 lakhs
8. Sponsor : Department of Atomic Energy (DAE), BRNS
Title : Development of medicated polymeric controlled release films of cardiac and

contraceptive drugs

9. Sponsor : All India Council for Technical Education (AICTE) (TAPTEC)
Title : Development of novel and industrially feasible transdermal drug delivery

systems
10. Sponsor : Janssen Cilag Pharmaceuticals, Johnson & Johnson, USA
Title : Use of lipid synthesis inhibitors and liposomes for enhancement of antifungal
efficacy
Total Amount :US$ 20,000/-
11. Sponsor :Bayer India
Title : Development of double layer tablet of pseudoephedrine and cetirizine
12. Sponsor : Bayer India
Title : Development of Moxifloxacine Tablets
13. Sponsor : Mac Laboratories
Title : Development of Novel drug delivery system
14. Sponsor :Rohm Pharma, Germany
Title : Eudragit RL PO based drug-in-adhesive transdermal system of estradiol

Total Amount : DM. 1500/-
Title : Evaluation of Diclofenac Sodium Topical Gels
16. Sponsor : Glenmark Pharmaceuticals
Title :Evaluation of topical Anti-fungal formulations
17. Sponsor : Choice Limited
Title : Development and evaluation of Herbal Cosmetic formulations
18. Sponsor : Orochem Technologies Inc.
Title : Development of Herbal Cosmetic formulations
Total Amount :US $ 6,000/-
19. Sponsor : Rusan Pharma
Title : Development of New drug delivery systems
Total Amount : Rs. 3,60,000/-
20. Sponsor : Bayer Healthcare Ltd
Title : Development of Combination Product

21. Sponsor : BASF
Title: Evaluation of Kollidon VA64 by HME process for immediate release dosage form
with different plasticizers and disintegrants.
22. Sponsor : UGC Major Research Project
Title: Design and Development of New Drug Delivery Systems of Anti-HIV Drugs
23. Sponsor : Nippon Synthetic Chemicals Ltd.
Title: Studies on polymeric materials
Total Amount: Rs. 7,30,000/-
(b) Current:
1. Department of Biotechnology with industry

collaboration Rs. 62,49,000/-
Development and Evaluation of Nanoparticular
Delivery System for Peptide drug
2. NAFETIC
Facility for Novel Drug Delivery System Rs. 73,00,000/-
3. Kusum Health Care Rs. 95,00,000/-

Development of Novel Formulations
4. Raptim Research Ltd.

Development of In-Vitro methods Rs. 8,38,830/-
Products developed at UICT

No Description Industry partner
1 Atorvastatin Tablets 20mg (ATSTAT) Kusum Healthcare Ltd
2 S(-)Amlodipine Tablet 2.5 mg & 5mg (SAMLOPIN)
3 Carbamazepine SR Tablet 400mg (MEZACAR 400)
Serratiopeptidase Enteric Coated Tablet 10mg
4
(SERRATA)
5 Aspirin Enteric Coated Tablet 75mg (LOSPIRIN)
6 Carbamazepine IR Tablet 200mg (MEZACAR 200)
Pantoprazole Enteric Coated Tablet 40mg
7
(ZOLAPAN)
8 Oxcarbazepine Tablet 300 mg (OXAPINE)
9 Itraconazole Tablets 100mg (ESZOLE)
10 Citicholine Tablets 500mg (NERODAR)
11 S(-)Amlodipine Atorvastatin Tablets (AMLOSTAT)
12 Clopidogrel Tablets (CLOPIGREL)
Metformine Acarbose Tablet (GLUCOBAY M 25 &
13 Bayer Pvt Ltd
GLUCOBAY M 50)
14 Rofecoxib Tablets (ROFF-BCD-50) Unichem Pvt Ltd
15 Fentanyl Transdermal Patch (FENSTUD) Rusan Pvt Ltd
Patents:
 WO2006123354
ORAL PHARMACEUTICAL COMPOSITION
Jyotsna Torne, Pradeep R. Vavia, Satyen Torne, Shankar Swaminathan,

Velidi Vijaya, Apichai Chancharusiri, Mehta Snehal, Mukund Pornchai,
Wongpayak Rajesh, Madhav Pai
 A process for manufacture of an oral sustained release Tablet dosage form having
one or more drugs in non-gas generating, floating, swellable and bioadhesive carrier
composition.
P.R.Vavia, Rajesh Shear, Paras Jain and Mahesh Chavanpatil.
(Indian Patent)
Indian Patent Filed (Complete Specification):
 Controlled release composition of macrolide antibiotics.

P.R.Vavia, Snehal Bhat
(Indian Patent)
 Biocapsules for drug delivery

P.R.Vavia, Sangwai M.B.
(Indian Patent)
 Novel silicone pressure sensitive adhesive composition for transdermal drug

delivery
P. R. Vavia, Khire Achyut
(Indian Patent)
 Amine resistant and non resistant silicone adhesive formulations of fentanyl and
devices for transdermal delivery
P. R. Vavia, Goyal Gaurav
(Indian Patent)
 Pharmaceutical formulation comprising combination of Metformin and acarbose

P. R. Vavia, Khan Mohammed Majed, Chavan Sandip
(Indian Patent)
 Oral pharmaceutical composition for controlled release of drug

P. R. Vavia, Sharad Darandale
(Indian Patent)
 Stable transdermal system of oxybutynin

(Indian Patent)
 Lornoxicam cyclodextrin and amino acid ternary inclusion complex

P. R. Vavia, Dinesh Brahmane
(Indian Patent)
 A novel multiparticulte controlled porosity osmotic pump of oxybutynin

hydrochloide
P. R. Vavia, Sharad Wawdhane
(Indian Patent)
 Solid antiretroviral oral composition

(Indian Patent)
 Oral concentrated nanoemulsion based formulation of tetrahydrolipstatin

P.R.Vavia, Sangwai Mayur
(Indian Patent)
 A novel hollow multiparticulate excipient for drug delivery

P.R.Vavia, Chavan Sandip
(Indian Patent)
 Novel immediate release telmisartan composition

(Indian Patent)
 Multiparticulate controlled porosity osmotic system

P.R.Vavia, Saindane Nilesh
(Indian Patent)
 Pharmaceutical composition for immediate release of weakly acidic potent drugs

P.R.Vavia, Vora Lalit
(Indian Patent)
 A pharmaceutical composition of niosomal gel for the topical delivery of

P.R.Vavia, Kumbhar Deepak
(Indian Patent)
 Oral Composition of calcium

(Indian Patent)
 Pharmaceutical composition containing crosslinked cyclodextrin polymer

P.R.Vavia, BrahmneDinesh
(Indian Patent)
 Ezetimibe nanosuspension and preparation method thereof

P.R.Vavia, Monpara Jasmin
(Indian Patent)
Indian Patent Filed (Provisional Application):
 Solid pharmaceutical composition of propofol

P.R.Vavia, Darandale Sharad
(Indian Patent)
 Solid lipid nanoparticles based formulation of antifungal agent and preparation

method thereof
P.R.Vavia, Wavikar Preeti
(Indian Patent)
 Solid oral pharmaceutical composition comprising of poorly water soluble drug

P.R.Vavia, Pawar Smita
(Indian Patent)
 Multiparticulate extended release pharmaceutical composition of carbamazepine

P.R.Vavia, Chavan Sandip
(Indian Patent)
 Nanoformulations for brain delivery

P.R.Vavia, Wavikar Preeti
(Indian Patent)
 Sublingual formulation of buprenorphine hydrochloride

P.R.Vavia, Yeola Gaurav
(Indian Patent)
 Pharmaceutical nasal spray composition for delivery of drugs

P.R.Vavia, Saindane Nilesh
(Indian Patent)
Seminars and Invited Talks
International:
 Invited as Speaker at the 20th Cyclodextrin Symposium And Asian Cyclodextrin

Conference, Chiba, Japan , 10th Sept. 2002.
 Invited Speaker, Presentation of research papers at 3 rd Asian Cyclodextrin

conference, Tianjin, China, 8th -12th May, 2005.
 Invited Speaker, Presentation of research papers at 13th International

Cyclodextrin Symposium, Totino, Italy, 14th -17th May, 2006.
 Invited Speaker, 2nd Congresso Nazionale, Chimica E Technologia Della

Ciclodestrine Asti, Italy, 3rd -5th May, 2009.
 Invited Speaker, “Dissolution method development, SUPAC guidelines and

biowaivers for pharmaceutical dosage forms” organized by Electrolab India, Thailand,
3rd Sept. 2009.
National
 Invited as Speaker and chief guest at the One day seminar on ‘Recent Advances in
Novel Drug Delivery Systems’ organized by IPA Pune Branch 2008.
 Invited as Speaker at the AICTE sponsored National seminar on ‘Current Trends

in Novel Drug Delivery Systems’ R.C. Patel Institute of pharmaceutical sciences and
research, Shirpur, Dhule August 2008.
 Invited as Speaker at the University of Pune sponsored sminar on ‘Formulation

Development ... problem based learning’, SKNCOP, Kndhawa, Pune October 2008.
 Invited as Speaker at the ICPPS-2009 and IPA convention – 2009, DPSAR

University, New Delhi, March 2009
 Invited as Speaker at the IPA sponsored seminar on ‘Stability Studies in
Pharmaceuticals’, Sci-Tech Center, Mumbai, May 2009
 Invited as a Speaker in University of Pune sponsored two day state level seminar
on “Recent trends in pharmaceutical technology” 5th & 6th Feb. 2010
 Invited as a Co-chairman, IPA convention-2010, Chennai, Tamil Nadu.
 Invited speaker, 62nd Indian Pharmaceutical Congress, Manipal 17 th – 19th Dec.

2010.
 Attended seminar on “CSR: Role of Pharmaceutical Sector in fight against

HIV/AIDS and TB” Mumbai, 27th April, 2010.
 Chief Guest and the speaker, AICTE National seminar on “Nanotechnology: A

versatile tool in drug design and technology” Organized by Agnihotri college of
pharmacy, Wardha, Nagpur, 7th June 2010.
 Invited speaker, Leveraging technological advances in Novel Drug Delivery

Systems, NDDS India, Mumbai, 19th-20th August 2010.
 Invited speaker, 62nd Indian Pharmaceutical Congress, Manipal 17 th – 19th Dec.

2010.
 Invited speaker, “Advances and Trends in Drug Delivery Process” State level
seminar, MIT college, Pune 5th -7th March 2011.
Conference/Symposia Presentations:
Total Research Presentations 204: (International-56, National-148)
1. Adhage N.A. and Vavia P.R., "Inclusion complexation of tolfenamic acid with -
cyclodextrins", at the 49th Indian Pharmaceutical Congress, Thiruvananthapuram,
18th-21st December, 1997.
2. Mare V.S. and Vavia P.R., "Aspects of quality control of transdermal therapeutic
systems-in-vitro drug release from transdermal patches of nitroglycerin", at the
49th Indian Pharmaceutical Congress, Thiruvananthapuram, 18 th-21st December,
1997.
3. Soman A.A. and Vavia P.R., "Design of liposomal gel formulations of diclofenac
sodium", at the 49th Indian Pharmaceutical Congress, Thiruvananthapuram, 18th-
21st December, 1997.
4. Kotiyan P.N., Bharti P.V. and Vavia P.R., "Synthesis and characterization of an
adhesive polymer for transdermal therapeutic system", at the 49 th Indian
Pharmaceutical Congress, Thiruvananthapuram, 18th-21st December, 1997.
5. Dhole S.N. and Vavia P.R., "Design and evaluation of oral controlled release aspirin
pellets by extrusion-spheronisation for cardiac patients", at the 49 th Indian
6. Soman A.A. and Vavia P.R., "Novel gel for nasal administration of vitamin B 12" at
the 49th Indian Pharmaceutical Congress, Thiruvananthapuram, 18th-21 st
December, 1997.
7. Mare V.S. and Vavia P.R., "Design and formulation of monolithic type transdermal
therapeutic system of nitroglycerin", at the 49th Indian Pharmaceutical Congress,
Thiruvananthapuram, 18th-21st December, 1997.
8. Jain A.K. and Vavia P.R. "Optimization of Proliposome S  as a penetraion

enhancer", at the 49th Indian Pharmaceutical Congress, Thiruvananthapuram, 18 th-
21st December, 1997.
9. Puthli S.P. and Vavia P.R., "High performance thin layer chromatographic
determination of levonorgestrel", at the 49 th Indian Pharmaceutical Congress,
10. Quenim U.S. and Vavia P.R., "Significance of load-mapping in approximation of

representative sampling in pharmaceutical coatings" at the 49 th Indian
11. Kinalekar M.S. and Vavia P.R., "Enzyme preparation using alkalophilic Bacillus for
the production of -cyclodextrins", at the 49th Indian Pharmaceutical Congress,
12. Purohit V.S., Bharati P.V., Lele V.R. and Vavia P.R., Development of monolithic
transdermal patch of Isosorbide dinitrate, at the 3rd International symposium on
innovations in pharmaceutical Sciences and Technology, 7th-9th February, 1997.
13. Vavia P.R. and Puthli S.P., "Poly (lactide-co-glycolide) microspheres of

levonorgestrel for parenteral contraception", at the 135th British Pharmaceutical
Conference, London, U.K., 8th - 11th September, 1998.
14. Indap M.A., Bhosale S.C., Vavia P.R. and Tayade P.T., "Quercetin - cyclodextrin
complex for chemotherapeutic investigation in cancer", Conference on Advances in
clinical pharmacology and workshop on basics of clinical pharmacology, Mumbai,
1st - 3rd February, 1998.
15. Puthli S.P. and Vavia P.R., "Stability indicating high performance thin layer
chromatographic determination of piroxicam", III International Symposium and
Short Course on Separation Sciences, Bhopal, India, 23 rd - 26th November, 1998.
16. Kotiyan P.N. and Vavia P.R., "Stability indicating high performance thin layer
chromatography for the estimation of estradiol", III International Symposium and
17. Kinalekar M.S., Kulkarni S. and Vavia P.R., "Simultaneous determination of alpha,
beta and gamma cyclodextrins by HPLC method", III International Symposium and
18. Puthli S.P. and Vavia P.R., "Studies on the effect of radiation sterilization on
biodegradable micro spheres", at the 50 th Indian Pharmaceutical Congress,
Mumbai, 10th - 13th December, 1998.
19. Adhage N.A. and Vavia P.R., "Grinding: A method for -cyclodextrins inclusion
complexation", at the 50th Indian Pharmaceutical Congress, Mumbai, 10 th - 13th
December, 1998.
20. Indap M.A., Bhosle S.C., Tayade P.T. and Vavia P.R., Preparation and antitumour
activity of quercetin-hydroxy propyl -cyclodextrins inclusion complexation", at
the 50th Indian Pharmaceutical Congress, Mumbai, 10th - 13th December, 1998.
21. Tayade P.T. and Vavia P.R., Evaluation of pharmacokinetic parameters of
ketoprofen and ketoprofen -cyclodextrins in healthy Indian male volunteers", at
the 50th Indian Pharmaceutical Congress, Mumbai, 10th - 13th December, 1998.
22. Kinalekar M.S. and Vavia P.R., "Optimization of ultrafiltration method as a tool for
the continuous production of -cyclodextrins at the 50th Indian Pharmaceutical
Congress, Mumbai, 10th - 13th December, 1998.
23. Kotiyan P.N. and Vavia P.R., "Prevention of drug crystallization in monolithic
transdermal systems of estradiol", at the 50 th Indian Pharmaceutical Congress,
24. Mare, V.S., Kotiyan, P.N. and Vavia, P.R., "Design and evaluation of acrylate based
pressure sensitive adhesives for transdermal drug delivery systems", at the 50 th
Indian Pharmaceutical Congress, Mumbai, 10th - 13th December, 1998.
25. Adhage N.A., Soman A.A. and Vavia P.R., "Anti-inflammatory and analgesic activity
of nimesulide--cyclodextrins inclusion complexation", at the 50 th Indian
Pharmaceutical Congress, Mumbai, 10th - 13th December, 1998.
26. Makhija S.N. and Vavia P.R., "Simultaneous estimation of pseudoephedrine and
cetirizine by reverse phase HPLC", at the 50 th Indian Pharmaceutical Congress,
27. Kotiyan P.N., Bharti P.V. and Vavia P.R., "Transdermal systems of estradiol:
fabrication and evaluation", at the 18 th Pharmaceutical Technology Conference,
Utrecht, The Netherlands, 13th - 15th April, 1999.
28. Soman A.A. and Vavia P.R., "Topical gel formulations: liposomal system for a non-
steroidal antiinflammatory agent", at the 18 th Pharmaceutical Technology
Conference, Utrecht, The Netherlands, 13th - 15th April, 1999.
29. Adhage N.A. and Vavia P.R., "A milling method for producing a nimesulide-beta-
cyclodextrin inclusion complex", at the 18 th Pharmaceutical Technology
Conference, Utrecht, The Netherlands, 13th - 15th April, 1999.
30. Puthli S.P., Bharadwaj Y.K., Majali A.B. and Vavia P.R., "A microparticulate
parenteral drug delivery system produced from a biodegradable polymer of
natural origin", at the 18th Pharmaceutical Technology Conference, Utrecht, The
Netherlands, 13th - 15th April, 1999.
31. Mare V.S., Bharti P.V. and Vavia P.R., "Design and in-vitro evaluation of a 'Drug-in-
adhesive' Transdermal System of Nitroglycerin", at the 18th Pharmaceutical
Technology Conference, Utrecht, The Netherlands, 13th - 15th April, 1999.
32. Mare V.S. and Vavia P.R., "Design and fabrication of drug in adhesive transdermal
systems of nitrate drugs using indigenous pressure sensitive adhesive", at the 51 st
Indian Pharmaceutical Congress, Indore, 18th - 20th December, 1999.
33. Kotiyan P.N. and Vavia P.R., "Vinyl acetate copolymer based drug-in-adhesive
transdermal system of estradiol", at the 51st Indian Pharmaceutical Congress,
Indore, 18th - 20th December, 1999.
34. Kotiyan P.N. and Vavia P.R., "Stability considerations in the development of
trasdermal steroidal delivery system", at the 51 st Indian Pharmaceutical Congress,
35. Shakleya D.M. and Vavia P.R., "Enhancement of anti-inflammatory activity of

diclofenac gel", at the 51st Indian Pharmaceutical Congress, Indore, 18 th - 20th
December, 1999.
36. Mare V.S. and Vavia P.R., "Controlling crystallization in transdermal patches of
ISDN in polyisobutylene matrix", at the 51 st Indian Pharmaceutical Congress,
37. Adhage N.A. and Vavia P.R. "Pharmacodynamic studies of tolfenamic acid: -
cyclodextrins inclusion complexes", at the 51st Indian Pharmaceutical Congress,
38. Adhage N.A. and Vavia P.R., "Evaluation of pharmacokinetic parameters of

nimesulide and nimesulide--cyclodextrin tablets", at the 51 st Indian
Pharmaceutical Congress, Indore, 18th - 20th December, 1999.
39. Makhija S.N. and Vavia P.R., "Stability indicating HPTLC method for the
simultaneous estimation of pseudoephedrine and cetirizine", at the 51 st Indian
40. Tipre D.N. and Vavia P.R., "Degradation kinetic study and stability indicating
HPTLC method of nitrendipine" at the 51st Indian Pharmaceutical Congress, Indore,
18th - 20th December, 1999.
41. Tipre D.N. and Vavia P.R., "Simultaneous estimation of losartan potassium and
hydrochlorothiazide using planar chromatography", at the 51 st Indian
42. Jain P.R. and Vavia P.R., "Development and validation of Stability indicating HPLC
method of niotinic acid", at the 51st Indian Pharmaceutical Congress, Indore, 18 th -
20th December, 1999.
43. Tipre D. N. and Vavia P. R., “Design and evaluation of Nitrendipine transdermal
delivery system.”, at the 3rd International symposium on Advances in technology
and Business Potential of new drug Delivery systems, Ootacamund, India, 30th-2nd
sept., 2000.
44. Shakleya D. M. and Vavia P. R., “Carbopol in Opthalmic formulations.”, at the 3rd
International symposium on Advances in technology and Business Potential of new
drug Delivery systems, Ootacamund, India, 30th-2nd sept., 2000.
45. Kulkarni S.S. and Vavia P.R., “ Novel decongestant bilayered tablets in modified
release dosage formsusing HPMC, at the 3rd International symposium on Advances
in technology and Business Potential of new drug Delivery systems, Ootacamund,
India, 30th-2nd sept., 2000.
46. Makhija S. N. and Vavia P.R., “Acrylate based osmotically controlled release
systems.” at the 3rd International symposium on Advances in technology and
Business Potential of new drug Delivery systems, Ootacamund, India, 30th-2nd sept.,
2000.
47. Tipre D.N. and Vavia P.R., “Eudragit E100 based drug in adhesive transdermal
system of Nicorandil.” at the 3rd International symposium on Advances in
technology and Business Potential of new drug Delivery systems, Ootacamund,
India, 30th-2nd sept., 2000.
48. Bhat S.S. and Vavia P.R., “Once daily sustained release antibiotic formulation, at
the 52ndIndian Pharmaceutical Congress, Hyderabad, 1st-3rd December, 2000.
49. Shakleya D..M.and Vavia P.R., “Topical gels of Meloxicam.” at the 52 nd Indian
Pharmaceutical Congress, Hyderabad, 1st-3rd December, 2000.
50. Makhija S.N. and Vavia P.R., “Osmotically controlled release systems of
Pseudoephedrine” at the 52ndIndian Pharmaceutical Congress, Hyderabad, 1st-3rd
December, 2000.
51. Jain P. R. and Vavia P. R.,” Sustained release Niacin tablets for cholesterol
lowering.” at the 52ndIndian Pharmaceutical Congress, Hyderabad, 1st-3rd December,
2000.
52. Manjrekar P. N. and Vavia P. R., “Inclusion complex of Mefenamic acid in  -

cyclodextrin: Preparation and properties.” at the 52 ndIndian Pharmaceutical
Congress, Hyderabad, 1st-3rd December, 2000.
53. Dawre F. D. and Vavia P. R., “Molecular encapsulation of Celecoxib in  -

cyclodextrin.” at the 52ndIndian Pharmaceutical Congress, Hyderabad, 1 st-3rd
December, 2000.
54. Makhija S.N. and Vavia P.R., “Stability indicating HPLC method for Venlafaxine, a
bicyclic antidepressant.” at the 52 ndIndian Pharmaceutical Congress, Hyderabad,
1st-3rd December, 2000.
55. Bhat SS and Vavia P. R., “Estimation of macrolide antibiotic, Clarithromycin by

colorimetric method.” at the 52ndIndian Pharmaceutical Congress, Hyderabad, 1st-
3rd December, 2000.
56. Kulkarni S. S. and Vavia P. R., “Colorimetric estimation of Cisapride using MBTH
from pharmaceutical dosage forms.” at the 52 ndIndian Pharmaceutical Congress,
Hyderabad, 1st-3rd December, 2000.
57. Tipre D. N. and Vavia P. R., “Concentration dependant photodegradation study of

Nitrendipine in organic solvents. at the 52 ndIndian Pharmaceutical Congress,
Hyderabad, 1st-3rd December, 2000.
58. Shakleya D. and Vavia P. R.,”Reverse phase HPLC determination of Rifampicin

from biological fluids.” at the 52 ndIndian Pharmaceutical Congress, Hyderabad, 1st-
3rd December, 2000.
59. Tipre D.N. and Vavia P.R. , “Stabilisation of Nicorandil with cyclodextrin for oral
and parenteral dosage forms.” at the 10th International symposium on Recent
Advances in Drug Delivery Systems, Salt Lake City, Utah, USA, Feb. 19-22,2001.
60. Makhija S.N. and Vavia P.R., “ Sustained release tablets of Venlafaxine, a non-
tricyclic antidepressant.” at the 10th International symposium on Recent Advances
in Drug Delivery Systems, Salt Lake City, Utah, USA, Feb. 19-22,2001.
61. Shakleya D.M. and Vavia P.R., “ Bioavailability of Rifampicin tablet in combination
with INH, Pyrazinamide and Ethambutol in healthy human volunteers.” at the 10th
International symposium on Recent Advances in Drug Delivery Systems, Salt Lake
City, Utah, USA, Feb. 19-22,2001.
62. Chavanpatil M. and Vavia P. R., “The influence of absorption enhancers on nasal
drug delivery of acyclovir.” at the 53 rd Indian Pharmaceutical Congress, New Delhi,
Dec. 20th -23rd, 2001.
63. Manjrekar P. N. and Vavia P.R., “Preparation of inclusion complex of Tamoxifen

citrate in -cyclodextrin and its evaluation against spontaneous mammary
tumour.” at the 53rd Indian Pharmaceutical Congress, New Delhi, Dec. 20 th -23rd,
2001.
64. Karnik A. D. and Vavia P. R., “Novel gel-sol injection of Doxycycline hydrochloride
for the treatment of periodontitis.” at the 53 rd Indian Pharmaceutical Congress,
New Delhi, Dec. 20th -23rd, 2001.
65. Jadhav G. S., Dawre F. D. and Vavia P. R., “Meloxicam in -cyclodextrin: an

approach to improve the therapeutic efficacy.” at the 53 rd Indian Pharmaceutical
Congress, New Delhi, Dec. 20th -23rd, 2001.
66. Shakleya D. and Vavia P. R., “Carbopol ® in ophthalmic formulation-II.” at the 53 rd

Indian Pharmaceutical Congress, New Delhi, Dec. 20th -23rd, 2001.
67. Chavanpatil M., Dawre F. D. and Vavia P. R., “Study on absorption of Rofecoxib and
its inclusion complex in -cyclodextrin by the rat everted intestinal sac model.” at
the 53rd Indian Pharmaceutical Congress, New Delhi, Dec. 20 th -23rd, 2001.
68. Jadhav G. S., Makhija S. N. and Vavia P. R., “Pharmacokinetic studies of Venlafaxine
SR tablets in healthy human volunteer.” at the 53rd Indian Pharmaceutical Congress,
New Delhi, Dec. 20th -23rd, 2001.
69. Shear R. S. and Vavia P. R., “Simple and rapid HPTLC estimation of Nimodipine.” at
the 53rd Indian Pharmaceutical Congress, New Delhi, Dec. 20 th -23rd, 2001.
70. Bhat S. S. and Vavia P. R., “Stability indicating HPLC method for macrolide
antibiotic, Clarithromycin.” at the 53 rd Indian Pharmaceutical Congress, New Delhi,
Dec. 20th -23rd, 2001.
71. Shear R. S. and Vavia P. R., “Development of HPTLC method for Nicorandil from
rat plasma.” at the 53rd Indian Pharmaceutical Congress, New Delhi, Dec. 20 th -23rd,
2001.
72. Jain P. R. and Vavia P. R., “Once daily sustained release niacin formulation.” at the
53rd Indian Pharmaceutical Congress, New Delhi, Dec. 20th -23rd, 2001.
73. Manjrekar P. N. and Vavia P. R., “Evaluation of Anti-tumour activity of

Diarylheptanoid from Curcuma species.” at the 53 rd Indian Pharmaceutical
74. Chavanpatil M. and Vavia P. R., “Simple and rapid High Perfomance Thin Layer
Chromatographic estimation of Amikacin sulphate from Pharmaceutical Dosage
form.” at the 53rd Indian Pharmaceutical Congress, New Delhi, Dec. 20th -23rd, 2001.
75. Jain P. R. and Vavia P. R., “Development and validation of stability indicating HPLC
method for Simvastatin.” at the 53rd Indian Pharmaceutical Congress, New Delhi,
Dec. 20th -23rd, 2001.
76. Choudhari S. V., Dawre F. D. and Vavia P. R., “Stability indicating HPLC method for
Rofecoxib – A novel selective COX-2 inhibitor.” at the 53 rd Indian Pharmaceutical
77. Chavanpatil M. and Vavia P. R., “Estimation of Moxifloxacin in pharmaceutical

dosage form by spectrophotometric and HPTLC method.” at the 53 rd Indian
Pharmaceutical Congress, New Delhi, Dec. 20th -23rd, 2001.
78. Karnik A. D., Chavanpatil M. and Vavia P. R., “Development and validation of
HPTLC method for the analysis of Doxycycline hydrochloride.” at the 53 rd Indian
Pharmaceutical Congress, New Delhi, Dec. 20th -23rd, 2001.
79. M.C.Patil and P.R.Vavia, “Enhancement of Nasal absorption of Acyclovir via

Cyclodextrins”, at the 11th International Cyclodextrin Symposium at Reykjavik,
Iceland, 5th – 8th May, 2002.
80. M.A.Indap, P. N. Manjrekar, P.R.Vavia, et.al., “ The bioflavonoid Quercetin: anti-

tumor activity and pharmacological manipulations for increased therapeutic
gains”, at the 18th UICC International Cancer Congress, Oslo – Norway, 30th June –
5th July, 2002.
81. M.C.Patil and P.R.Vavia, “ Once Daily Sustained Release Formulation of

Cephalexin”, at the 4th International Symposium on Advances and Business
Potential of Novel Drug Delivery Systems, Mumbai, India, 23rd – 25th July, 2002.
82. P.R. Jain and P.R.Vavia, “Amoxicillin Sustained Release for improved therapeutic
efficacy”, at the 4th International Symposium on Advances and Business Potential of
Novel Drug Delivery Systems, Mumbai, India, 23rd – 25th July, 2002.
83. P.R.Vavia and F.D.Dawre, “Preparation and Characterization of Beta-Cyclodextrin

Complexes with Non-Steroidal Anti-Inflammatory Agents” at the 20th Cyclodextrin
Symposium And Asian Cyclodextrin Conference, Chiba, Japan , 10th Sept. 2002.
84. P.R.Vavia, J.S.Torne and G.S.Jadhav, “Cyclodextrin Complex with Anti-HIV Drug”
20th Cyclodextrin Symposium And Asian Cyclodextrin Conference, Chiba, Japan , 10th
Sept. 2002.
85. Dawre F. D. Torne J.S. and Vavia P. R., “Studies on Anti-inflammatory and
Analgesic Activity of Celecoxib and its Inclusion Complex with -Cyclodextrin” at
the 54th Indian Pharmaceutical Congress, Pune, Dec. 13th –15th, 2002.
86. Chavanpatil M. and Vavia P.R., “Development and validation of stability indicating
HPLC method for Sumatriptan Succinate” at the 54th Indian Pharmaceutical
Congress, Pune, Dec. 13th –15th, 2002.
87. Jain P.R., Chavanpatil M.D. and Vavia P.R.,“ High Performance Liquid
Chromatographic Estimation of Ofloxacin From Human Plasma” at the 54th Indian
Pharmaceutical Congress, Pune, Dec. 13th –15th, 2002.
88. Jain P.R., Chavanpatil M.D. and Vavia P.R., “ Development and Validation of
Stability Indicating HPLC Method for Ofloxacin” at the 54th Indian Pharmaceutical
89. Chaudhari S.V. and Vavia P.R, “Reverse phase stability indicating HPLC method of
Terbinafine Hydrochloride” at the 54th Indian Pharmaceutical Congress, Pune, Dec.
13th –15th, 2002.
90. Manjrekar P. N. and Vavia P. R., “Inclusion complex of Diarylheptanoids in

-cyclodextrin: Preparation and properties” at the 54th Indian Pharmaceutical
91. Shah R.C. and Vavia P. R., “Molecular Encapsulation of Clonazepam in -

Cyclodextrin” at the 54th Indian Pharmaceutical Congress, Pune, Dec. 13th –15th,
2002.
92. Tandale R. S. and Vavia P. R., “Precise and Accurate HPLC Method for Estimation
of Clotrimazole and Beclomethasone Dipropionate in cream” at the 54th Indian
93. J. Balakrishnan, D. M. Shakleya and P. R. Vavia, “Topical Nimesulide Gel” at

the 54th Indian Pharmaceutical Congress, Pune, Dec. 13th –15th, 2002.
94. R. C. Shah, D. M. Shakleya and P. R. Vavia, “Fast Acting Diclofenac

Diethylammonium Gel” at the 54th Indian Pharmaceutical Congress, Pune, Dec.,
13th –15th, 2002.
95. Rajendra S.T. and Vavia P. R., “Estimation of Rofecoxib and counterirritants from
novel emulgel using new sensitive and precise HPLC method” at the 54th Indian
96. Tandale R.S. and Vavia P. R. “Novel Rofecoxib Emulgel for Effective Pain
Management” at the 54th Indian Pharmaceutical Congress, Pune, Dec. 13th –15th,
2002.
97. P.R. Vavia, Jyotsna S. Torne, F.D. Dawre and Dilip Pawar, “Bioavailability Studies of
Rofecoxib-Beta-cyclodextrin Tablets” Poster Presentation at 63rd International
Congress of FIP, Sydney, Australia, 2002.
98. P.R. Vavia, Jyotsna S. Torne “Cyclodextrin Based Drug Delivery System of ANTI -
HIV Drug” Poster Presentation at 63rd International Congress of FIP Sydney,
Australia, 2002.
99. P.R. Vavia, P.R. Jain M.C. Patil, “Once Daily Controlled Release Ofloxacin
formulation” Poster Presentation at 63rd International Congress of FIP Sydney,
Australia, 2002.
100. Vavia P. R., Agnihotri S.M., “A novel biodegradable polymers for drug delivery” at
the 55th Indian Pharmaceutical Congress, Chennai, Dec. 21st –23rd, 2004.
101. Vavia P.R., Jadhav G.J., “Development and validation of photostability indicating
HPLC methods for Danazol” at the 55th Indian Pharmaceutical Congress, Chennai,
Dec. 21st –23rd, 2004.
102. Vavia P.R., Choudhari S.V., “ Once daily sustained release cefadroxil formulation”
at the 55th Indian Pharmaceutical Congress, Chennai, Dec. 21st –23rd, 2004.
103. Vavia P.R., Patel A.R.,“ Molecular encapsulation of fenofibrate in Beta-

cyclodextrin” at the 55th Indian Pharmaceutical Congress, Chennai, Dec. 21st –
23rd, 2004.
104. Vavia P.R., Jadhav G.J., “Pharmacodynamic studies of valdecoxib and beta-
cyclodextrin inclusion complex” at the 55th Indian Pharmaceutical Congress,
Chennai, Dec. 21st –23rd, 2004.
105. Vavia P.R., Tandale R.S., “Estimation of valdecoxib and counter irritants for novel
emulgel using new, sensitive and precise HPLC method” at the 55th Indian
Pharmaceutical Congress, Chennai, Dec. 21st –23rd, 2004.
106. Vavia P. R., Agnihotri S.M., “Influence of process parameters on nanoparticle

preparation performed by a double emulsion ultrasonication technique”
NATCOSEB XI, Mumbai.
107. Vavia P. R., Sonaje G.R., Choudhari S.V. “Once daily sustained release formulation
of cefadroxil” at the 55th Indian Pharmaceutical Congress, Chennai, Dec. 21st –
23rd, 2004.
108. Vavia P. R., Tandale R.S., “Development of Novel Valdecoxib Emulsion Gel with
counter-irritants for effective pain management ” at the 55th Indian
Pharmaceutical Congress, Chennai, Dec. 21st –23rd, 2004.
109. Vavia P. R., Torne J.S., “Solubility enhancement of anti-HIV drug – Nelfinavir
Mesylate by Beta-cyclodextrin complexation” 5th Controlled Release Society
symposia on Advances in Technology and Business potential in NDDS, 16th-
17th Feb. 2004.
110. Vavia P. R., Torne J.S., “Once daily sustained release formulation of anti-HIV drug –
Stavudine” 5th Controlled Release Society symposia on Advances in Technology
and Business potential in NDDS, 16th-17th Feb. 2004.
111. Vavia P. R., Jadhav G.J., “Development and pharmacodynamic evaluation of tablet
containing inclusion complex of valdecoxib with beta-cyclodextrin” 5th Controlled
Release Society symposia on Advances in Technology and Business potential in
NDDS, 16th-17th Feb. 2004.
112. Vavia P. R., Tandale R.S., “Development of novel emulsion gel with counter
irritants for effective pain management"5th Controlled Release Society symposia
on Advances in Technology and Business potential in NDDS, 16th-17th Feb. 2004.
113. Vavia P. R., Bhat S.S., “Clarithromycin sustained release formulation for improved
efficasy” 5th Controlled Release Society symposia on Advances in Technology and
Business potential in NDDS, 16th-17th Feb. 2004.
114. Vavia P. R., Agnihotri S.M., “Development and evaluation of novel diclofenac
sodium loaded polymeric colloidal dispersion system” 5th Controlled Release
Society symposia on Advances in Technology and Business potential in NDDS,
16th-17th Feb. 2004.
115. Goyal Gaurav * and Vavia P. R., Topical Sildenafil Gel : A Novel Highly Permeable
Delivery System For Erectile Dysfunction., 56th Indian Pharmaceutical Congress,
3rd –5th Dec.2004.
116. Torne J. S. and Vavia P. R., “Development of HPLC method for Self Micro-
Emulsifying Drug Delivery System (Smedds) of immunosuppressant” 56th Indian
Pharmaceutical Congress, 3rd –5th Dec.2004.
117. Rajendra S. T. and Vavia P. R., “Novel Extended Drug Delivery Of Metformin” 56th
Indian Pharmaceutical Congress, 3rd –5th Dec.2004 , Kolkata.
118. Gajanan S. and Vavia P. R., “Once Daily Osmotic Tablet Of Oxybutynin
Hydrochloride” 56th Indian Pharmaceutical Congress, 3rd –5th Dec.2004.
119. Ashwini D. Karnik, A. Adhikary, S. Chaudhari, R. Tandale, Vavia P.R., “Development

of Novel Fast disintegrating Tablet formulation of Cefuroxime Axetil” 56th Indian
Pharmaceutical Congress, 3rd –5th Dec.2004.
120. Ashok R. Patel and Vavia P. R., “Aceclofenac - β-Cyclodextrin Systems:

Preparation, Characterization and In- vitro Evaluation”56th Indian Pharmaceutical
Congress, 3rd –5th Dec.2004.
121. Patel A.R. and Vavia P. R., “Evaluation of PVPVA as a carrier in Solid Dispersion”
56th Indian Pharmaceutical Congress, 3rd –5th Dec.2004.
122. Jadhav G. S, Nandedkar T. D. and Vavia P. R, “Oral Contraceptive Activity of Novel

Formulation of PRV-GJ-03 in Mice” 56th Indian Pharmaceutical Congress, 3rd –5th
Dec.2004.
123. Pathan S.M. , Jadhav G.S. and Vavia P.R., “Prepartion and Characterization of
Inclusion Complex of Danazol with b-Cyclodextrin” 56th Indian Pharmaceutical
124. Agnihotri S. M., Jadhav G. S. and Vavia P. R., “Development and Validation of
Stability Indicating HPLC Method For Valdecoxib”, 56th Indian Pharmaceutical
125. Ripal G.J., Jadhav G.S. and Vavia P.R., “Development and Optimization of Tablet
Formulation containing Inclusion Complex of Etoricoxib in b-Cyclodextrin” 56th
Indian Pharmaceutical Congress, 3rd –5th Dec.2004.
126. Vavia P. R., Torne J.S., “Solubility enhancement of anti-HIV drug by Beta-
cyclodextrin Inclusion complexation” 3rd Asian Cyclodextrin Conference, 8th-12th
May, 2005.
127. Patel A.R. and Vavia P.R., “Effect of hydrophilic polymer on solubilization of
fenofibrate by Cyclodextrin complexation” 3rd Asian Cyclodextrin
Conference,China, 8th-12th May, 2005.
128. Patel A.R., Jadhav G.S. and Vavia P. R., “Interaction of Valdecoxib with Beta
Cyclodextrin- Experimental and molecular modeling studies” 3rd Asian
Cyclodextrin Conference, China, 8th-12th May, 2005.
129. Adhikary A.R., Karnik A.D., and Vavia P.R., “Development and Evaluation of
Gastro-Retentive Drug Delivery System of Rantidine HCl using Two Different
Approaches” 2nd International Symposium on Drug Discovery and Process
Research, Belgaum, 10th to 12th February, 2006.
130. Ansari Khalid Akhter, Vavia P.R., “Development of Novel Sustained Release
System: Disintegration Controlled Matrix Tablet with Solid Dispersion Granules of
Felodipine” 2nd International Symposium on Drug Discovery and Process
Research, Belgaum, 10th to 12th February, 2006.
131. Karnik A.D., Adhikary A.R. and Vavia P.R., “Development and Evaluation of
Modified Release Tablets of Gliclazide 80mg” 2nd International Symposium on
Drug Discovery and Process Research, Belgaum, 10th to 12th February, 2006.
132. Patel A.R., Ansari Khalid Akhter, Vavia P.R., “Emerging Trends in Nano- Enabled
Aerosol Drug delivery System” 2nd International Symposium on Drug Discovery
and Process Research, Belgaum, 10th to 12th February, 2006.
133. Shankar Swaminathan, Vavia P.R., “Nanosponge based Drug Delivery of

Cilostazol” 2nd International Symposium on Drug Discovery and Process Research,
Belgaum, 10th to 12th February, 2006.
134. Vavia, P.R., Swaminattan, S., Trotta, F., Cavalli, R., ” Applications of Nanosponges in
Drug Delivery” XIII International Cyclodextrin Symposium , pp. 14-17, 2006.
135. Sonaje G.R. Vavia P.R., “Development of Sustained Release Tablet of Tizanidine
HCl” 2nd International Symposium on Drug Discovery and Process Research,
Belgaum, 10th to 12th February, 2006.
136. Vavia P.R., Francesco Trotta, Shankar Swaminathan, “Formulation of Itraconazole
nanosponges” XIII International Cyclodextrin Symposium, Torino, Italy, 14th-17th
May, 2006.
137. Patel A.R., Vavia P.R., “Ternary complexation as a Novel approach for Taste
masking: studies with Famotidine” XIII International Cyclodextrin Symposium,
Torino, Italy, 14th-17th May, 2006.
138. Benival D.M., Vavia P.R., “Inclusion Behavior of Carbamazepine and

Oxcarbamazepine: A comparative study” XIII International Cyclodextrin
Symposium, Torino, Italy, 14th-17th May, 2006.
139. Shankar Swaminathan and Vavia P.R. “Formulation of Itraconazole glasses: A

disordered drug delivery approach” The seventh International symposium of
Controlled release society, Indian Chapter, Mumbai, Feb. 2007.
140. Satyen Torne, P.R. Vavia, “Nanosponge Based Drug Delivery System of Paclitaxel”
presented at Controlled Release Society, Indian Chapter 2007.
141. Patel A. R., P.R. Vavia, “Triacetin based self emulsifying formulation of a poorly
water soluble drug” 59th Indian Pharmaceutical Congress, Dec 2007.
142. Patel A.R., P.R. Vavia, “Effect of β-Cyclodextrin complexation on the intestinal
permeability of Fenofibrate” 59th Indian Pharmaceutical Congress, Dec 2007.
143. Shelar D. B., P. R. Vavia, “Development of Carbamazepine extended release

formulation as per USP using HPMC hydrophilic matrices” 59 th Indian
Pharmaceutical Congress, Dec. 2007.
144. Sandip Chavan, Shankar Swaminathan, P. R. Vavia, “Novel multi unit particulate
system (MUPS) for effective delivery of Itraconazole” 59 th Indian Pharmaceutical
Congress, Dec. 2007.
145. Kunal P. Pagar, P. R. Vavia, “Synthesis and characterization of L-lactide-

depsipeptide copolymer and its application in nanoparticle synthesis” 59 th Indian
Pharmaceutical Congress, Dec 2007.
146. Gosavi H. R., P. R. Vavia, “Effects of excipient on the stability of Serratiopeptidase

enteric coated tablets” 59th Indian Pharmaceutical Congress, Dec 2007.
147. Wawdhane S.R., P.R. Vavia, “Formulation of extended release matrix tablet of
Furosemide using cellulose polymers” 59 th Indian Pharmaceutical Congress, Dec
2007.
148. Mali N. D., P. R. Vavia, “Design and evaluation of oral disintegrating tablet of
Tramadol Hydrochloride” 59th Indian Pharmaceutical Congress, Dec. 2007.
149. Nagpal Amit, P. R. Vavia, “Development and evaluation of oral extended release
tablets of Nalbuphine” 59th Indian Pharmaceutical Congress, Dec. 2007.
150. Mayur Sangwai, P. R. Vavia, “Design and evaluation of yeast encapsulated drug
delivery system (YEDDS)” 59th Indian Pharmaceutical Congress, Dec. 2007.
151. Khan M. Majed, P. R. Vavia, “Development of aqueous based enteric coated

Aspirin tablets” 59th Indian Pharmaceutical Congress, Dec.2007.
152. Ansari Khalid Akhtar, P. R. Vavia, “Development of directly compressible extended

release once daily tablet of Felodipine” 59th Indian Pharmaceutical Congress, Dec.
2007.
153. Kunal Pagar, Shankar Swaminathan, P. R. Vavia, “Investigation of solution state

interaction of nanosponges and various poorly soluble drugs by Ultraviolet
spectroscopy” 59th Indian Pharmaceutical Congress, Dec. 2007.
154. F. Trotta, R. Cavalli, S. Swaminathan, C. Sarzanini, P. R. Vavia. “Novel functionalized

nanosponges: synthesis, characterization, safety assessment, cytotoxicity testing
and interaction studies” The XIV International Cyclodextrin Symposium, Kyoto,
Japan, May 2008.
155. R. Cavalli, F. Trotta, P. R. Vavia , S. Swaminathan, M. Trotta, “Nanosponge based

prolonged release injectable formulations of camptothecin” The XIV International
Cyclodextrin Symposium, Kyoto, Japan, May 2008.
156. Gaurav Goyal, Vavia P.R., “Design and evaluation of drug-in-adhesive fentanyl
transdermal bioequivalent therapeutic system” 35th Annual Meeting of CRS, New
York, USA , July 2008.
157. Gosavi H.R., Vavia P.R., “Evaluation of Kollidon ® SR in once a day sustained release
tablets of trimetazidine hydrochloride” 60 th Indian Pharmaceutical Congress, Dec.
2008.
158. Shankar Swaminathan, Vavia P. R., Cavalli R., Trotta F. “Nanosponge based drug
delivery systems of dexamethasone” 60 th Indian Pharmaceutical Congress, Dec.
2008.
159. Majed Khan, Vavia P.R., “Development and validation of stability indicating RP-
HPLC method for estimation of pentoprazole in pantoprazole enteric coated
tablets” 60th Indian Pharmaceutical Congress, Dec. 2008.
160. Wawdhane S.R., Vavia P.R., “A new multiparticulate controlled porosity osmotic
pump(CPOP) of oxybutynin hydrochloride” 60 th Indian Pharmaceutical Congress,
Dec. 2008.
161. Chavan S.S., Vavia P.R., “Effect of calcium hydrogen phosphate dihydrate and
calcium hydrogen phosphate anhydrous on hardness of pyridoxine tablets 50mg a
case study” 60th Indian Pharmaceutical Congress, Dec. 2008.
162. Shelar D.B., Vavia P.R., “Tablet formulation studies of Oxcarbazepine-poloxamer

binary system” 60th Indian Pharmaceutical Congress, Dec. 2008.
163. Mali N.D., Vavia P.R., “Design of bi-layer sustained release tablet formulation of
Domperidone Maleate” 60th Indian Pharmaceutical Congress, Dec. 2008.
164. Bramhane D.M., Vavia P.R., “Preparation, evaluation and characterization of

lornoxicam: β-cyclodextrin and arginine ternary complex” 60 th Indian
165. Saindane N.S., Vavia P.R., “Synthesis of water soluble β-cyclodextrin polymers and
to explore their application in enhancing solubility of water insoluble drug” 60 th
Indian Pharmaceutical Congress, Dec. 2008.
166. Sangwai M.B., Vavia P.R., “Effect of various excipients on orally disintegrating
tablet of S(-) Amlodipine Besylate” 60th Indian Pharmaceutical Congress, Dec.
2008.
167. Pagar K.P., Ansari K.A., Vavia P.R., “Development and validation of stability
indicating HPLC Method for estimation of felodipine in SNEDDS formulation” 60 th
168. Darandale S.S., Vavia P.R., “Design and evaluation of novel gastroretentive films of
poorly soluble drug” 60th Indian Pharmaceutical Congress, Dec. 2008.
169. Khire A.S., Vavia P.R., “Studies on novel soft high solids containing pressure
sensitive adhesive for transdermal therapeutic system” 60 th Indian Pharmaceutical
170. Meer T.S., Vavia P.R., “Development of enteric coated multiparticulate drug
delivery system for aspirin” 60th Indian Pharmaceutical Congress, Dec. 2008.
171. Pawar S.K., Vavia P.R., “Preparation and evaluation of self-microemulsifying drug
delivery system of Tacrolimus” 60th Indian Pharmaceutical Congress, Dec. 2008.
172. Gosavi H. R., Vavia P. R. “ Novel approaches for Solubilization of Nisoldipine” 9 th

Controlled Released Scociety- Indian chapter, Feb. 2009
173. Swaminathan S., Vavia P. R.,Trotta. F, Cavalli. R “Existence of Crystalline and Para-
crystalline forms of Nanosponges of Beta-cyclodextrin and its Effect on
Solubilization of a Model Drug”9 th Controlled Released Society- Indian chapter, Feb.
2009.
174. Vavia P.R., Swaminathan S, Torne S.J., Trotta F., Cavalli R., “Nanosponges:
Fabrication, Characterization and Applications in Drug delivery”, An oral invited
presentation at the II Italian Cyclodextrin symposium held in Asti, Italy in May
2009.
175. Shankar Swaminathan, Pradeep Vavia, Manuela Donalisio , Maria Eugenia

Carlotti, Francesco Trotta, David Lembo , Roberta Cavalli, “Characterization Of
Antiviral Activity Of Acyclovir-Loaded Carboxylated Nanosponges”, a poster
Presentation at the II Italian Cyclodextrin symposium held in Asti, Italy in May
2009.
176. Shankar Swaminathan*, Pradeep R. Vavia, Francesco Trotta, Roberta Cavalli,

Loredana Serpe, Gian Paolo Zara. “Novel Functionalized Beta Cyclodextrin
Nanosponge Based Stable Formulation Of Camptothecin And In Vitro Cytotoxicity
Evaluation”, A poster presented at the Fifth Asian cyclodextrin conference in Busan,
Korea in May 2009.
177. Shankar Swaminathan, Pradeep R. Vavia, Ansari Khalid Akhter, Francesco Trotta,
Roberta Cavalli, “New applications of Cyclodextrin Based Nanosponges”, An Invited
presentation at the Fifth Asian Cyclodextrin conference in Busan, Korea in May
2009.
178. Ansari Khalid Akhter, P. R. Vavia, Francesco trotta, Roberta Cavalli, “Novel Beta
Cyclodextrin for Delivery of Resveratrol In vitro Characterisation, Cytotoxicity and
permeation Study” The 5th Asian Cyclodextrin Conference(ACC2009), May 2009 .
179. Hemgir Gosavi, P. R. Vavia, “Development and validation of simultaneous analysis

of atenolol and hydrochlorothiazide by high performance liquid chromatography”
21st International Symposium on Pharmaceutical and Biomedical Analysis 2009.
180. Dinesh M Bramhane, Pradeep R. Vavia, Poster Presentation entitled: Inclusion
Complexation of Weakly Acidic NSAID with β -Cyclodextrin: Selection of Arginine,
an Amino Acid, As a Novel Ternary Component, First European Cyclodextrin
Conference 11th -13th Oct 2009, Aalborg, Denmark.
181. Nilesh S. Siandane, Pradeep R. Vavia, Poster Presentation Entitled : Synthesis and
Characterization of Amphiphilic Star Copolymer of Beta-cyclodextrin and
Polypropylene Oxide and Their Application as Nanocarrier, First European
Cyclodextrin Conference 11th -13th Oct 2009, Aalborg, Denmark.
182. Ansari Khalid Akhter, P. R. Vavia, Francesco trotta, Roberta Cavalli, Poster
Presenatation: Nanosponges as long term oxygen delivery Carrrier, Annual Meeting
Controlled Release Society (CRS) 2009, Denmark.
183. Sharad Wawdhane, P. R. Vavia, A Multiparticulate Based Controlled Porosity
Osmotic Pump (CPOP) of Oxybutynin HCl, AAPS Annual Meeting and Exposition,
2009, LA, USA.
184. Mayur Sangwai, P. R. Vavia, Effect of various formulation variables on
encapsulation efficiency and integrity of preformed yeast biocapsules for oral
itraconazole delivery, AAPS Annual Meeting and Exposition, 2009, LA, USA.
185. Mali N.D., Vavia P.R., “Development and validation of stability indicating isocratic
RP-HPLC method for analysis of domperidone in domperidone sustained release
tablets” 61st Indian Pharmaceutical Congress, Dec. 2009.
186. Shelar D.B., Vavia P.R., “Preparation and characterization glass solutions of
poorely soluble drug using hot melt extrusion technique” 61 st Indian
187. Bramhane D.M., Vavia P.R., “New LC method for determination of lornoxicam
assay and impurities content in tablet formulation” 61 st Indian Pharmaceutical
188. Pagar K.P., Vavia P.R., “Development of timed release film-coated felodipine
tablets for chronotherapeutic application in heart” 61 st Indian Pharmaceutical
189. Darandale S.S., Vavia P.R., “Gastroretentive drug loaded polymeric films-method
of preparation and characterization” 61st Indian Pharmaceutical Congress, Dec.
2009.
190. Vora L. K., Vavia P.R., “Enhancement of solubility and dissolution rate of
lercanidipine with parent cyclodextrin and modified cyclodextrin” 61 st Indian
191. Wavikar P., Vavia P.R., “Topical solid lipid nanoparticles of antimycotic
agent:terbinafine HCL” 61st Indian Pharmaceutical Congress, Dec. 2009.
192. Jadhav N., Vavia P.R., “Enteric coated multiple unit particulate system of
pantoprazole sodium sesquehydrate” 61 st Indian Pharmaceutical Congress, Dec.
2009.
193. Swaminathan S., Sharad W., Vavia P.R., “Development and validation of a stability
indicating isocratic RP-HPLC method for estimation of itraconazole from a novel
tablet formulation” 61st Indian Pharmaceutical Congress, Dec. 2009.
194. Sharad W., Vavia P. R. “ A novel extended release bilayer matrix tablet of
furosemide, 10th Controlled Released Scociety- Indian chapter, Feb. 2010
195. Shelar D.B., Vavia P. R. “ SMECTITE clay as a controlled release material for
Carbamazepine delivery” 10th Controlled Released Scociety- Indian chapter, Feb.
2010
196. Shelar D.B., Vavia P. R. “Self-Nanoemulsifying Drug Delivery Systems of

Isradipine: Design and Optimization” 37th annual meeting and exposition of
controlled release society, Oregon, USA, 2010
197. Mali N.D., Vavia P.R. “Development and validation of RP-HPLC method for
determination of methylparaben sodium, propyl paraben sodium and potassium
sorbate in citicoline oral solution” 62nd Indian Pharmaceutical Congress, Dec. 2010.
198. Gavhane S.P., Vavia P.R., “Development and evaluation of monolithic transdermal
patch for chronic pain” 62nd Indian Pharmaceutical Congress, Dec. 2010.
199. Saindane N.S., Pagar K.P., Vavia P.R. “Controlled release formulation of glipizide
based on interpolymer complexation of carbopol-hydroxypropyl methyl cellulose,
62nd Indian Pharmaceutical Congress, Dec. 2010.
200. Kumbhar D.P., Vavia P.R. “Topical lornxicam niosomal gel formulation for
treatment of rheumatoid arthritis” 62nd Indian Pharmaceutical Congress, Dec.
2010.
201. Jasmin D.M., Vavia P.R. “Preparation of ezetimibe nanocrystals by

nanoprecipitation method for enhanced aqueous solubility and dissolution rate”
62nd Indian Pharmaceutical Congress, Dec. 2010.
202. Brahmne D.M., Vavia P.R. “ Crosslinked β-cyclodextrin polymer: Novel excipients
for controlled drug delivery system” 62nd Indian Pharmaceutical Congress, Dec.
2010.
203. Vora L.K., Vavia P.R. “Ternary complexation of repaglinide with Hydroxypropyl β-
cyclodextrin and meglumine for solubility and dissolution enhancement” 62nd
Complete list of publications (peer reviewed + others)
International:
1. Patel K, Tyagi M, Monpara J, Vora L, Gupta S, Vavia P. Arginoplexes: an arginine-

anchored nanoliposomal carrier for gene delivery. Journal of Nanoparticle
Research. 2014;16(4).
2. Pagar KP, Sardar SM, Vavia PR. Novel L-lactide-depsipeptide polymeric carrier for
enhanced brain uptake of rivastigmine in treatment of alzheimer's disease. Journal
of Biomedical Nanotechnology. 2014;10(3):415-26.
3. Khire A, Vavia P. Electron capture detection of oxybutynin in plasma: Precolumn

derivatization approach and application to a pharmacokinetic study. Analytical
Methods. 2014;6(5):1455-61.
4. Wavikar P, Vavia P. Nanolipidgel for enhanced skin deposition and improved
antifungal activity. AAPS PharmSciTech. 2013;14(1):222-33.
5. Torne S, Darandale S, Vavia P, Trotta F, Cavalli R. Cyclodextrin-based nanosponges:

effective nanocarrier for tamoxifen delivery. Pharmaceutical development and
technology. 2013;18(3):619-25.
6. Swaminathan S, Vavia PR, Trotta F, Cavalli R, Tumbiolo S, Bertinetti L, et al.

Structural evidence of differential forms of nanosponges of beta-cyclodextrin and
its effect on solubilization of a model drug. Journal of Inclusion Phenomena and
Macrocyclic Chemistry. 2013;76(1-2):201-11.
7. Swaminathan S, Vavia PR, Trotta F, Cavalli R. Nanosponges encapsulating

dexamethasone for ocular delivery: Formulation design, physicochemical
characterization, safety and corneal permeability assessment. Journal of
Biomedical Nanotechnology. 2013;9(6):998-1007.
8. Swaminathan S, Sangwai M, Wawdhane S, Vavia P. Soluble itraconazole in tablet

form using disordered drug delivery approach: Critical scale-up considerations and
bio-equivalence studies. AAPS PharmSciTech. 2013;14(1):360-74.
9. Shelar DB, Pawar SK, Vavia PR. Fabrication of isradipine nanosuspension by anti-
solvent microprecipitation-high-pressure homogenization method for enhancing
dissolution rate and oral bioavailability. Drug Delivery and Translational Research.
2013;3(5):384-91.
10. Sardar S, Pagar K, Sangwai M, Vavia P. Monolithic osmotic system of lornoxicam

using amorphous ternary cyclodextrin complex as a core. International Journal of
PharmTech Research. 2013;5(2):730-45.
11. Sangwai M, Vavia P. Amorphous ternary cyclodextrin nanocomposites of

telmisartan for oral drug delivery: Improved solubility and reduced
pharmacokinetic variability. International Journal of Pharmaceutics.
2013;453(2):423-32.
12. Saindane NS, Pagar KP, Vavia PR. Nanosuspension based in situ gelling nasal spray
of carvedilol: Development, in vitro and in vivo characterization. AAPS
PharmSciTech. 2013;14(1):189-99.
13. Patel K, Sarma V, Vavia P. Design and evaluation of Lumefantrine - Oleic acid self
nanoemulsifying ionic complex for enhanced dissolution. DARU, Journal of
Pharmaceutical Sciences. 2013;21(1).
14. Patel K, Pati A, Mehta M, Gota V, Vavia P. Medium chain triglyceride (MCT) rich,
paclitaxel loaded self nanoemulsifying preconcentrate (PSNP): A safe and
efficacious alternative to taxol®. Journal of Biomedical Nanotechnology.
2013;9(12):1996-2006.
15. Pagar KP, Vavia PR. Poly[LA-(Glc-Leu)] copolymer as a carrier for ocular delivery of
ciprofloxacin: Formulation, characterization and in vivo biocompatibility study.
Therapeutic Delivery. 2013;4(5):553-65.
16. Pagar K, Vavia P. Rivastigmine-loaded L-lactide-depsipeptide polymeric

nanoparticles: Decisive formulation variable optimization. Scientia Pharmaceutica.
2013;81(3):865-85.
17. Nandedkar TD, Sagvekar P, Thakur B, Navlakhe R, Chitnis S, Mahale SD, et al.
Polymeric nanoparticle formulation of octapeptide (NP-OP): In vitro release and in
vivo effect in common marmosets, Callithrix jacchus Linn. Indian Journal of
Experimental Biology. 2013;51(12):1055-62.
18. Mali N, Darandale S, Vavia P. Niosomes as a vesicular carrier for topical

administration of minoxidil: Formulation and in vitro assessment. Drug Delivery
and Translational Research. 2013;3(6):587-92.
19. Lembo D, Swaminathan S, Donalisio M, Civra A, Pastero L, Aquilano D, et al.

Encapsulation of Acyclovir in new carboxylated cyclodextrin-based nanosponges
improves the agent's antiviral efficacy. International Journal of Pharmaceutics.
2013;443(1-2):262-72.
20. Kumbhar D, Wavikar P, Vavia P. Niosomal gel of lornoxicam for topical delivery: In
vitro assessment and pharmacodynamic activity. AAPS PharmSciTech.
2013;14(3):1072-82.
21. Khire A, Vavia P. Effect of permeation enhancers on dynamic mechanical properties

of acrylate pressure sensitive adhesives. International Journal of Pharmaceutics.
2013;458(1):141-7.
22. Darandale SS, Vavia PR. Cyclodextrin-based nanosponges of curcumin: Formulation
and physicochemical characterization. Journal of Inclusion Phenomena and
23. Chavan SS, Ingle SG, Vavia PR. Preparation and characterization of solid lipid
nanoparticle-based nasal spray of budesonide. Drug Delivery and Translational
Research. 2013;3(5):402-8.
24. Bramhane DM, Jadhav NV, Vavia PR. Development, characterisation and evaluation
of supersaturated triglyceride free drug delivery (s-TFDDS) of lornoxicam. Drug
Delivery and Translational Research. 2013;3(5):392-401.
25. Bandarkar FS, Vavia PR. Physico-chemical characterization and in vivo

pharmacodynamic evaluation of lyophilized meloxicam: β-cyclodextrin inclusion
complexes. International Journal of Pharmacy and Pharmaceutical Sciences.
2013;5(3):159-65.
26. Swaminathan S, Darandale S, Vavia PR. Technology improves bioavailability of

some drugs, offers formulation versatility and holds potential for a revolution in
nano therapies. Pharmaceutical Formulation and Quality. 2012(6).
27. Saindane N, Vavia P. Osmotic pellet system comprising osmotic core and in-process
amorphized drug in polymer-surfactant layer for controlled delivery of poorly
water-soluble drug. Journal of Pharmaceutical Sciences. 2012;101(9):3169-79.
28. Pawar SK, Vavia PR. Rice germ oil as multifunctional excipient in preparation of
self-microemulsifying drug delivery system (SMEDDS) of tacrolimus. AAPS
PharmSciTech. 2012;13(1):254-61.
29. Pawar SK, Badhwar AJ, Kharas F, Khandare JJ, Vavia PR. Design, synthesis and
evaluation of N-acetyl glucosamine (NAG)-PEG-doxorubicin targeted conjugates for
anticancer delivery. International Journal of Pharmaceutics. 2012;436(1-2):183-
93.
30. Pagar KP, Vavia PR. Felodipine b-cyclodextrin complex as an active core for time
delayed chronotherapeutic treatment of hypertension. Acta Pharmaceutica.
2012;62(3):395-410.
31. Goyal G, Vavia PR. Complexation approach for fixed dose tablet formulation of
lopinavir and ritonavir: An anomalous relationship between stability constant,
dissolution rate and saturation solubility. Journal of Inclusion Phenomena and
32. Trotta F, Cavalli R, Martina K, Biasizzo M, Vitillo J, Bordiga S, et al. Cyclodextrin

nanosponges as effective gas carriers. Journal of Inclusion Phenomena and
33. Sangwai MB, Vavia PR. Effect of decisive formulation variables on bioencapsulation
efficiency and integrity of yeast biocapsules for oral itraconazole delivery. Journal
of Microencapsulation. 2011;28(4):311-22.
34. Saindane NS, Bramhane DM, Vavia PR. Synthesis and characterization of
amphiphilic star copolymer of beta-cyclodextrin and polypropylene oxide and their
application as nanocarriers. Journal of Inclusion Phenomena and Macrocyclic
Chemistry. 2011;69(3-4):383-92.
35. Bramhane DM, Saindane NS, Vavia PR. Inclusion complexation of weakly acidic
NSAID with β-cyclodextrin: Selection of arginine, an amino acid, as a novel ternary
component. Journal of Inclusion Phenomena and Macrocyclic Chemistry.
2011;69(3-4):453-60.
36. Bandarkar FS, Vavia PR. An optimized commercially feasible milling technique for
molecular encapsulation of meloxicam in β-cyclodextrin. Drug Development and
Industrial Pharmacy. 2011;37(11):1318-28.
37. Ansari KA, Vavia PR, Trotta F, Cavalli R. Cyclodextrin-based nanosponges for
delivery of resveratrol: In vitro characterisation, stability, cytotoxicity and
permeation study. AAPS PharmSciTech. 2011;12(1):279-86.
38. Ansari KA, Torne SJ, Vavia PR, Trotta F, Cavalli R. Paclitaxel loaded nanosponges: In-
vitro characterization and cytotoxicity study on MCF-7 cell line culture. Current
Drug Delivery. 2011;8(2):194-202.
39. Torne SJ, Ansari KA, Vavia PR, Trotta F, Cavalli R. Enhanced oral paclitaxel
bioavailability after administration of paclitaxel-loaded nanosponges. Drug
Delivery. 2010;17(6):419-25.
40. Swaminathan S, Pastero L, Serpe L, Trotta F, Vavia P, Aquilano D, et al. Cyclodextrin-
based nanosponges encapsulating camptothecin: Physicochemical
characterization, stability and cytotoxicity. European Journal of Pharmaceutics and
Biopharmaceutics. 2010;74(2):193-201.
41. Swaminathan S, Cavalli R, Trotta F, Ferruti P, Ranucci E, Gerges I, et al. In vitro

release modulation and conformational stabilization of a model protein using
swellable polyamidoamine nanosponges of β-cyclodextrin. Journal of Inclusion
Phenomena and Macrocyclic Chemistry. 2010;68(1):183-91.
42. Patel AR, Vavia PR. SMEDDS incorporated polymer matrix: A floating dosage form
solution for drugs with poor gastric solubility. Pharmaceutical Technology Europe.
2010;22(3):36-42.
43. Patel AR, Vavia PR. Evaluation of synthesized cross linked polyvinyl alcohol as
potential disintegrant. Journal of Pharmacy and Pharmaceutical Sciences.
2010;13(2):114-27.
44. Cavalli R, Akhter AK, Bisazza A, Giustetto P, Trotta F, Vavia P. Nanosponge

formulations as oxygen delivery systems. International Journal of Pharmaceutics.
2010;402(1-2):254-7.
45. Puthli SP, Vavia PR. Fabrication, characterization and in vivo studies of
biodegradable gamma sterilized injectable microparticles for contraceptionVavia.
Pharmaceutical Development and Technology. 2009;14(3):278-89.
46. Puthli S, Vavia PR. Stability studies of microparticulate system with piroxicam as
model drug. AAPS PharmSciTech. 2009;10(3):872-80.
47. Puthli S, Vavia P. Formulation and performance characterization of radio-sterilized

"Progestin-only" microparticles intended for contraception. AAPS PharmSciTech.
2009;10(2):443-52.
48. Bandarkar FS, Vavia PR. A stability indicating HPLC method for the determination
of meloxicam in bulk and commercial formulations. Tropical Journal of
Pharmaceutical Research. 2009;8(3):257-64.
49. Agnihotri SM, Vavia PR. Diclofenac-loaded biopolymeric nanosuspensions for
ophthalmic application. Nanomedicine: Nanotechnology, Biology, and Medicine.
2009;5(1):90-5.
50. Agnihotri SM, Vavia PR. Drug loaded poly[Lac(Glc-Leu)] microparticles:

Formulation and release characteristics. Colloids and Surfaces B: Biointerfaces.
2009;74(1):336-9.
51. Agnihotri SM, Vavia PR. Pharmacokinetics of intramuscular microparticle depot of

valdecoxib in an experimental model Pharmacokinetics of intramuscular
microparticle depot. Drug Development and Industrial Pharmacy.
2009;35(9):1043-7.
52. Puthli S, Vavia P. Gamma irradiated micro system for long-term parenteral
contraception: An alternative to synthetic polymers. European Journal of
Pharmaceutical Sciences. 2008;35(4):307-17.
53. Patel AR, Vavia PR. Preparation and evaluation of taste masked famotidine
formulation using drug/β-cyclodextrin/polymer ternary complexation approach.
AAPS PharmSciTech. 2008;9(2):544-50.
54. Jadhav GS, Vavia PR. Physicochemical, in silico and in vivo evaluation of a danazol-
β-cyclodextrin complex. International Journal of Pharmaceutics. 2008;352(1-2):5-
16.
55. Adhikary A, Vavia PR. Bioadhesive ranitidine hydrochloride for gastroretention

with controlled microenvironmental pH. Drug Development and Industrial
Pharmacy. 2008;34(8):860-9.
56. Torne SJ, Torne JS, Vavia PR, Singh SK, Kishore N. Cyclodextrin based drug delivery
system of protease inhibitor - Nelfinavir mesylate. Journal of Inclusion Phenomena
and Macrocyclic Chemistry. 2007;57(1-4):689-97.
57. Swaminathan S, Vavia PR, Trotta F, Torne S. Formulation of betacyclodextrin based

nanosponges of itraconazole. Journal of Inclusion Phenomena and Macrocyclic
Chemistry. 2007;57(1-4):89-94.
58. Patel AR, Vavia PR. Nanotechnology and pharmaceutical inhalation aerosols. Indian
Journal of Experimental Biology. 2007;45(2):166-74.
59. Patel AR, Vavia PR. Preparation and in vivo evaluation of SMEDDS (self-
microemulsifying drug delivery system) containing fenofibrate. AAPS Journal.
2007;9(3):E344-E52.
60. Jadhav GS, Vavia PR, Nandedkar TD. Danazol-β-cyclodextrin binary system: A
potential application in emergency contraception by the oral route. AAPS
PharmSciTech. 2007;8(2).
61. Torne JS, Vavia PR. Inclusion complexation of Anti-HIV drug with β-cyclodextrin.
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 2006;56(1-2):253-9.
62. Tayade P, Vavia P. Inclusion complexes of Ketoprofen with β-cyclodextrins: Oral

pharmacokinetics of ketoprofen in human. Indian Journal of Pharmaceutical
Sciences. 2006;68(2):164-70.
63. Patel AR, Vavia PR. Effect of hydrophilic polymer on solubilization of fenofibrate by
cyclodextrin complexation. Journal of Inclusion Phenomena and Macrocyclic
Chemistry. 2006;56(1-2):247-51.
64. Jadhav GS, Patel AR, Vavia PR, Malde AK, Coutinho EC. Interaction of valdecoxib
with β-cyclodextrin: Experimental and molecular modeling studies. Journal of
Inclusion Phenomena and Macrocyclic Chemistry. 2006;56(1-2):261-73.
65. Chavanpatil MD, Jain P, Chaudhari S, Shear R, Vavia PR. Novel sustained release,
swellable and bioadhesive gastroretentive drug delivery system for ofloxacin.
International Journal of Pharmaceutics. 2006;316(1-2):86-92.
66. Chaudhari S, Karnik A, Adhikary A, Tandale R, Vavia P. Simultaneous UV

spectrophotometric method for the estimation of cefuroxime axetil and probenecid
from solid dosage forms. Indian Journal of Pharmaceutical Sciences.
2006;68(1):59-63.
67. Tayade PT, Vavia PR. Sustained release agglomerates of ibuprofen using natural
polymer and thermal gelation technique. Indian Journal of Pharmaceutical
Sciences. 2005;67(6):697-702.
68. Chavanpatil MD, Vavia PR. Nasal drug delivery of sumatriptan succinate.
Pharmazie. 2005;60(5):347-9.
69. Chavanpatil M, Jain P, Chaudhari S, Shear R, Vavia P. Development of sustained
release gastroretentive drug delivery system for ofloxacin: In vitro and in vivo
evaluation. International Journal of Pharmaceutics. 2005;304(1-2):178-84.
70. Kotiyan PN, Vavia PR, Bhardwaj YK, Sabarwal S, Majali AB. Electron beam
irradiation: A novel technology for the development of transdermal system of
isosorbide dinitrate. International Journal of Pharmaceutics. 2004;270(1-2):47-54.
71. Chavanpatil MD, Vavia PR. The influence of absorption enhancers on nasal
absorption of acyclovir. European Journal of Pharmaceutics and Biopharmaceutics.
2004;57(3):483-7.
72. Tipre DN, Vavia PR. Acrylate-based transdermal therapeutic system of

nitrendipine. Drug Development and Industrial Pharmacy. 2003;29(1):71-8.
73. Tipre DN, Vavia PR. Acrylate-based pressure sensitive adhesive in fabrication of
transdermal therapeutic system. Polymers for Advanced Technologies.
2003;14(7):502-7.
74. Makhija SN, Vavia PR. Controlled porosity osmotic pump-based controlled release
systems of pseudoephedrine: I. Cellulose acetate as a semipermeable membrane.
Journal of Controlled Release. 2003;89(1):5-18.
75. Barkume MS, Tayade PT, Vavia PR, Indap MA. Antiproliferative effect of aspirin and
its inclusion complex on human MCF-7 and K-562 cancer cells in vitro. Indian
Journal of Pharmaceutical Sciences. 2003;65(5):486-91.
76. Agnihotri SM, Vavia PR. Influences of process parameters on nanoparticle

preparation performed by a double emulsion ultrasonication technique. Journal of
Surface Science and Technology. 2003;19(3-4):183-7.
77. Tipre DN, Vavia PR. Formulation optimization and stability study of transdermal
therapeutic system of nicorandil. Pharmaceutical Development and Technology.
2002;7(3):325-32.
78. Makhija SN, Vavia PR. Stability indicating LC method for the estimation of
venlafaxine in pharmaceutical formulations. Journal of Pharmaceutical and
Biomedical Analysis. 2002;28(6):1055-9.
79. Makhija SN, Vavia PR. Once daily sustained release tablets of venlafaxine, a novel
antidepressant. European Journal of Pharmaceutics and Biopharmaceutics.
2002;54(1):9-15.
80. Kotiyan PN, Vavia PR, Bharadwaj YK, Sabarwal S, Majali AB. Electron beam
processed transdermal delivery system for administration of an anti-anginal agent.
Radiation Physics and Chemistry. 2002;65(6):641-6.
81. Kotiyan PN, Vavia PR. Synthesis and characterization of an acrylate pressure
sensitive adhesive for transdermal drug delivery. Polymers for Advanced
Technologies. 2002;13(2):137-43.
82. Indap MA, Bhosle SC, Tayade PT, Vavia PR. Evaluation of toxicity and antitumour
effects of a hydroxypropyl β-cyclodextrin inclusion complex of quercetin. Indian
Journal of Pharmaceutical Sciences. 2002;64(4):349-53.
83. Chavanpatil M, Vavia PR. Enhancement of nasal absorption of acyclovir via

cyclodextrins. Journal of Inclusion Phenomena. 2002;44(1-4):137-40.
84. Chavanpatil M, Dawre FD, Shakleya DS, Vavia PR. Enhancement of oral
bioavailability of rofecoxib using β-cyclodextrin. Journal of Inclusion Phenomena.
2002;44(1-4):145-9.
85. Tipre DN, Vavia PR. Oxidative degradation study of nitrendipine using stability
indicating, HPLC, HPTLC and spectrophotometric method. Journal of
Pharmaceutical and Biomedical Analysis. 2001;24(4):705-14.
86. Mare VS, Bharti PV, Vavia PR. Synthesis and characterization of a novel soluble
reactive ladder-like polysilsesquioxane with side-chain 2-(4-Chloromethyl phenyl)
ethyl groups. Polymers for Advanced Technologies. 2001;12(8):475-81.
87. Makhija SN, Vavia PR. Stability indicating HPTLC method for the simultaneous
determination of pseudoephedrine and cetirizine in pharmaceutical formulations.
Journal of Pharmaceutical and Biomedical Analysis. 2001;25(3-4):663-7.
88. Kotiyan PN, Vavia PR. Eudragits: Role as crystallization inhibitors in drug-in-
adhesive transdermal systems of estradiol. European Journal of Pharmaceutics and
Biopharmaceutics. 2001;52(2):173-80.
89. Vavia PR, Adhage NA. Freeze-dried inclusion complexes of tolfenamic acid with β-
cyclodextrins. Pharmaceutical Development and Technology. 2000;5(4):571-4.
90. Tipre DN, Vavia PR. Degradation kinetic study of nicorandil using HPTLC method.
Indian Drugs. 2000;37(9):412-6.
91. Puthli SP, Vavia PR. Stability indicating HPTLC determination of piroxicam. Journal
of Pharmaceutical and Biomedical Analysis. 2000;22(4):673-7.
92. Kotiyan PN, Vavia PR. Stability indicating HPTLC method for the estimation of
estradiol. Journal of Pharmaceutical and Biomedical Analysis. 2000;22(4):667-71.
93. Kinalekar MS, Kulkarni SR, Vavia PR. Simultaneous determination of α, β and γ
cyclodextrins by LC. Journal of Pharmaceutical and Biomedical Analysis.
2000;22(4):661-6.
94. Dubhashi SS, Vavia PR. HPTLC method to study skin permeation of acylovir. Journal
of Pharmaceutical and Biomedical Analysis. 2000;23(6):1017-22.
95. Dubhashi SS, Vavia PR. Stability indicating reverse phase HPLC method for
acyclovir. Indian Drugs. 2000;37(10):464-8.
96. Adhage NA, Vavia PR. β-cyclodextrin inclusion complexation by milling. Pharmacy
and Pharmacology Communications. 2000;6(1):13-7.
97. Vavia PR, Tayade PT. Inclusion Complexation of Ketoprofen with β-Cyclodextrins.
Indian Journal of Pharmaceutical Sciences. 1999;61(1-6):97-9.
98. Vavia PR, Adhage NA. Inclusion complexation of nimesulide with β-cyclodextrins.
Drug Development and Industrial Pharmacy. 1999;25(4):543-5.
99. Tipre DN, Vavia PR. Estimation of Sumatriptan succinate in pharmaceutical dosage
form by spectrophotometric and HPTLC method. Indian Drugs. 1999;36(8):501-5.
100. Puthli SP, Vavia PR. Poly(lactide-co-glycolide) microparticulate system of

piroxicam. Proceedings of the Controlled Release Society. 1999(26):1110-1.
101. Kotiyan PN, Vavia PR. Eudragit®RL PO based drug-in-adhesive transdermal

system of estradiol. Proceedings of the Controlled Release Society. 1999(26):397-8.
102. Vavia PR, Puthli SP. Poly (lactide-co-glycolide) microspheres of levonorgestrel for
parenteral contraception. Journal of Pharmacy and Pharmacology. 1998;50(SUPPL.
9):144.
103. Indap MA, Bhosle SC, Vavia PR, Tayade PT. Quercetin-cyclodextrin complex and
it's chemotherapeutic investigations in cancer. Indian Drugs. 1998;35(9):545-9.
104. Bhalla HL, Vavia PR, Samuel G, Sivaprasad N. Development of radioimmunoassay.

I. Preparation of radiolabeled tracers theophylline. Journal of Radioanalytical and
Nuclear Chemistry. 1997;220(1):73-6.
105. Sapre AG, Ramjilal, Sivaprasad N, Vavia PR. Synthesis of an immunogen and a
novel radiotracer of estradiol. Journal of Radioanalytical and Nuclear Chemistry.
1996;214(4):291-301.
106. Tike CA, Hegde DA, Naik MM, Vavia PR, Tipnis HP. Bioequivalence studies of
angiotensin converting enzyme inhibitors. Part VII (captopril). Indian Drugs.
1995;32(4):155-9.
107. Tike CA, Hegde DA, Naik MM, Vavia PR, Tipnis HP. Bioequivalence studies of
angiotensin converting enzyme inhibitors: Part VIII - Pharmacokinetic interaction
between captopril and hydrochlorthiazide. Indian Drugs. 1995;32(5):217-24.
108. Naik MM, Hegde DA, Tike CA, Vavia PR, Tipnis HP. Pharmacokinetic studies of
new angiotensin converting enzyme inhibitors marketed abroad - Part VI
(Quinapril, Benazepril and Trandolapril). Indian Drugs. 1995;32(3):116-9.
109. Hegde DA, Naik MM, Tike CA, Vavia PR, Tipnis HP. Bioequivalence studies of
angiotensin converting enzyme inhibitors: Part V - Pharmacokinetic interaction
between lisinopril and hydrochlorothiazide. Indian Drugs. 1995;32(2):84-9.
110. Tike CA, Vavia PR, Naik MM, Tipnis HP. Bioequivalence studies of angiotensin
converting enzyme inhibitors: Part II (enalapril maleate). Indian Drugs.
1994;31(4):155-9.
111. Naik MM, Tike CA, Vavia PR, Tipnis HP. Pharmacokinetics studies of new
angiotensin converting enzyme inhibitors marketed in India and abroad: Part III
(perindopril and cilazapril). Indian Drugs. 1994;31(5):197-200.
112. Hegde DA, Naik MM, Vavia PR, Tipnis HP. Bioequivalence studies of angiotensin
converting enzyme inhibitors: Part IV - Pharmacokinetic interaction between
enalapril maleate and hydrochlorthiazide. Indian Drugs. 1994;31(10):479-84.
113. Tike CA, Vavia PR, Tipnis HP. Bioequivalence studies of angiotensin converting
enzyme inhibitors: Part - I (lisinopril). Indian Drugs. 1992;29(13):601-4.
National: (21)
1. Bhalla H.L. and Vavia P.R., Effect of enhancers on in-vitro permeation of
ketoprofen, Indian Drugs, 26(5): 247, 1989.
2. Tike C.A., Vavia P.R., and Tipnis H.P., Bioequivalence studies of angiotensin
converting enzyme inhibitors : Part I (Lisinopril), Indian Drugs, 29(13) : 601,
1992.
3. Vavia P.R., Tike C.A., Naik M. and Tipnis H.P., Bioequivalence studies of
angiotensin converting enzyme inhibitors : Part II (Enalapril Maleate), Indian
Drugs, 31(4) : 155,1994.
4. Vavia P.R., Tike C.A., Naik M. and Tipnis H.P., Pharmacokinetic studies of new
angiotensin converting enzyme inhibitors marketed in India and abroad: Part III
(Perindopril and Cilazapril), Indian Drugs, 31(5) : 197, 1994.
5. Vavia P.R., Tike C.A., Naik M. and Tipnis H.P., Hegde D.A. Bioequivalence studies of
angiotensin converting enzyme inhibitors: Part IV Pharmacokinetic interaction
between enalapril maleate and hydrochlorthiazide, Indian Drugs, 31(10) : 479,
1994.
6. Vavia P.R., Tike C.A., Naik M. and Tipnis H.P., Hegde D.A. Bioequivalence studies of
angiotensin converting enzyme inhibitors: Part V Pharmacokinetic interaction
between lisinopril and hydrochlorthiazide, Indian Drugs, 32(2) : 84, 1995.
7. Vavia P.R., Tike C.A., Naik M. and Tipnis H.P., Hegde D.A. Pharmacokinetic studies
of new angiotensin converting enzyme inhibitors: Part VI (Quinapril, Benazaril
and Tendaropril), Indian Drugs, 32(3) : 116, 1995.
8. Vavia P.R., Tike C.A., Naik M. and Tipnis H.P., Hegde D.A.,Bioequivalence studies of
angiotensin converting enzyme inhibitors: Part VII (Captopril), Indian Drugs,
34(4) : 155, 1995.
9. Vavia P.R., Tike C.A., Naik M. and Tipnis H.P., Hegde D.A., Bioequivalence studies of
angiotensin converting enzyme inhibitors: Part VIII Pharmacokinetic interaction
between captopril and hydrochlorthiazide, Indian Drugs, 32(5) : 217, 1995.
10. Indap M.A., Bhosle S.C., Vavia P.R. and Tayade P.T., Quercetin-cyclodextrin complex
and it's chemotherapeutic investigations in cancer, Indian Drugs, 35(9) Sep. 1998.
11. Vavia P.R. and Tayade P.T., Inclusion complexation of ketoprofen with -
cyclodextrins, Indian Journal of Pharmaceutical Sciences, 61(2): 97-99, 1999.
12. Tipre D.N. and Vavia P.R., Estimation of sumatriptan succinate in pharmaceutical
dosage from by spectrophotometric and HPTLC method, Indian Drugs, 36(8)
August, 1999.
13. Tipre D.N. and Vavia P.R, Degradation Kinetic study of nicorandil using HPTLC
method, Indian Drugs, 37(9) 412-416, 2000.
14. Dubhashi S.S. and Vavia P.R., Stability indicating reverse phase HPLC method for
Acyclovir, Indian Drugs, 37 (10) 464-468, 2000.
15. Indap, M.A., Bhosle, S.C., Tayade, P.T., Vavia, P.R., Evaluation of toxicity and
antitumour effects of a hydroxypropyl β-cyclodextrin inclusion complex of
quercetin, Indian Journal of Pharmaceutical Sciences 64 (4), 349-353, 2002
16. Tandale R.S., Vavia P.R., Meghana Abhyankar, Dilip pawar, Comparative evaluation
of Anti-inflammatory efficacy of Roff-Gel with other marketed topical gels, Indian
Medical Gazette, 302-309, August 2003.
17. Barkume M.S., Tayade P.T., Vavia P.R., Indap M.A., Antiproliferative effect of
Aspirin and its inclusion complex on human MCF-7 and K-562 cancer cells in-
vitro, Indian Journal of Pharmaceutical sciences, 65(5), 486-491, 2003.
18. Jadhav, G.S., Vavia, P.R., Development and pharmacodynamic evaluation of tablet
containing inclusion complex of valdecoxib with β-cyclodextrin, Indian J. Pharm.
Sci. 60, 525-526, 2004.
19. Tayade, P.T., Vavia, P.R., Sustained release agglomerates of ibuprofen using
natural polymer and thermal gelation technique, Indian Journal of
Pharmaceutical Sciences 67 (6), pp. 697-702, 2005.
20. Chaudhari S.V., Karnik Ashwani, Adhikary Anuradha, Tandale R.S.,Vavia P.R.,
“Simultaneous UV spectrophotometric method for the estimation of cefuroxime
axetil and probenecid from solid dosage forms ”Indian Journal of Pharmaceutical
Sciences, , 68(1), 1-132, 2006.
21. A.R. Patel and P.R. Vavia, Nanotechnology and pharmaceutical inhalation aerosols,
Indian Journal of Experimental Biology, 45, 166-174, 2007.

Prof. P. R. Vavia Resume

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Prof. P.R.

 Cyclodextrins based drug delivery systems

B.Pharm, B.Tech Pharma, M.Pharm (Pharmaceutics, Advanced pharmaceutics,

Awards, Honours and Accolades:

 Junior Research Fellow of Department of Atomic Energy

 Senior Research Fellow of Department of Atomic Energy

 Fellow, Indian Pharmaceutical Association, 2003 awarded at Indian

 Johnson and Johnson, USA, Research Award (US$ 20,000), 2001.

 Maharashtra Fellow for Medical Sciences, 2006.

 Best Teacher’s Award, University Institute of Chemical Technology at

 Distinguish Teacher Award, Maharashtra Pharmacy Association, 2009.

 “Incentives to Meritorious Teachers”, Dr. K. H. Gharda Reward, Board of

 Best Teacher’s Award, University Institute of Chemical Technology at

 Unichem Laboratories Ltd.

 Bayer India Ltd.

 Glenmark Pharmaceuticals Ltd.

 Jhonson & Jhonson Ltd.

 Medicap Ltd. (Bangkok, Thailand.)

 Kusum Health Care

Master students Guided: 38

Ph.D Students Guided: 29

Current research students:

1. Sponsor :Franco India Pharmaceuticals Limited

Title :Design and evaluation of diclofenac gel

Total Amount : Rs. 10,000/-

2. Sponsor : Cipla Limited

Title :Development and evaluation of topical formulations.

Total Amount : Rs. 1.5 lakhs

3. Sponsor :Johnson & Johnson Limited

Title :Evaluation of anti-fungal creams and development of validated analytical

4. Sponsor : Chin Chem.

Title : Design of sustained release isosorbide dinitrate pellet formulation

Total Amount : Rs. 25,000/-

5. Sponsor : Cipla Limited

Title : Development and evaluation of acyclovir liposomal gel formulation

Total Amount : Rs. 25,000/-

6. Sponsor :UDCT Golden Jubilee Research Fund

Title : Synthesis and evaluation of terpolymer for transdermal therapeutic system

Total Amount : Rs. 22,000/-

7. Sponsor : Unichem Laboratories

Title : Development of Novel drug delivery system

Total Amount : Rs. 1 lakhs

8. Sponsor : Department of Atomic Energy (DAE), BRNS

Title : Development of medicated polymeric controlled release films of cardiac and

Total Amount : Rs. 6.8 lakhs

Title : Development of novel and industrially feasible transdermal drug delivery

Total Amount : Rs. 10 lakhs

10. Sponsor : Janssen Cilag Pharmaceuticals, Johnson & Johnson, USA

Total Amount :US$ 20,000/-

11. Sponsor :Bayer India

Title : Development of double layer tablet of pseudoephedrine and cetirizine

Total Amount : Rs. 1 lakhs

12. Sponsor : Bayer India

Title : Development of Moxifloxacine Tablets

Total Amount : Rs. 1 lakhs

13. Sponsor : Mac Laboratories

Title : Development of Novel drug delivery system

Total Amount : Rs. 2.5 lakhs

14. Sponsor :Rohm Pharma, Germany

Title : Eudragit RL PO based drug-in-adhesive transdermal system of estradiol

15. Sponsor : Cipla Limited

Title : Evaluation of Diclofenac Sodium Topical Gels

Total Amount : Rs. 1 lakhs