Medical Study

Centre

6
01
-2
Session 2011-2016

11
20
We the team of medical study centre session

n
io
2011-2016 have copmiled these pharma
ss
mnemonics unit wise. We hope our effort of
mnemonics collection will help you all in proff.
se

We want that this collection must be shared with

re

your friends and fellows .please give us your feed

nt

back about this collection in our group and page

ce

Regards: admin Panel

dy

ALI Zeeshan(QAMC)
tu

ATHAR ALI (QAMC)

ls

Noreen FATIMA (FJMC)

a

https://www.facebook.com/groups/Medical.study.ce
ic

ntre/
ed

http://atharali187.blogspot.com/
M

atharali187.blogspot.com
 Pharmacology
Mnemonics

6
01
-2
General pharma

11
20
n
io
ss
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 1. Zero order kinetics drugs in high doses

APE

Aspirin

6
Phenytoin

01
Ethanol

-2
11
2. P450 inhibitors

20
IQ SMACKD

Isoniazid

n
Quinolones io
ss
Spironolactone
se

Macrolides
re

Amiodarone
nt

Cimetidine
ce

Ketoconazole
dy

Dapsone
tu
lsa
ic
ed
M

atharali187.blogspot.com
 3. P450 inducers

6
GTQ CRABS

01
Grisofulvin

-2
Tetracyclin

11
Quinidine

20
Carbamazepine

Rifampin

n
Alcohol io
ss
Barbiturates
se

Sulfa drugs
re

4. Enzymes Inhibitors
nt

"Vit. K Cannot Cause Enzyme Inhibition"

ce

 Valproate
dy

 Ketaconazole
tu

 Cimetidine
ls

 Ciprofloxacin
a
ic
ed
M

atharali187.blogspot.com
  Erythromycin

 INH

6
5. ototoxicity causative agents

01
A+.B.C.D. "

-2
 Aminoglycosides* (Profound and irreverible hair cell

11
loss)

20
 Barbiturates

 Cytotoxic drugs-Nitrogen mustard & cisplatin affect

n
Organ of corti (irreversible)
io
ss
 Diuretics-Ethacrynic acid, frusemide cause Ionic changes
se

(reversible)
re

6. enzymes inhibitor
nt

COMIC CASE '

ce

 Cimetidine
dy

 Omeprazole
tu

Metronidazole
ls


a
ic
ed
M

atharali187.blogspot.com
  Isoniazid

 Chloramphenicol

 Ciprofloxacin

6
 Allopurinol

01
 Sulphonamides

-2
 Erythromycin

11
20
7. drugs metabolized by acetylation

n
SHIP'
io
Sulfonamides including dapsone
ss

se

 Hydralazine

Isoniazid (INH)
re

Procainamide
nt


ce

8. teratogenic drugs :major non-antibiotics

dy

TAP CAP:
tu

Thalidomide
ls


a
ic
ed
M

atharali187.blogspot.com
  Androgens

 Progestins

 Corticosteroids

6
 Aspirin & indomethacin

01
 Phenytoin

-2
11
9. therapeutic index formula

20
'TILE':

n
TI = LD50 / ED50
io
ss
se

10. drug with low therapeutic index

re
nt
ce

'The Queen Likes to Dig Low'

 Theophylline
dy

 Quinine
tu

Lithium
ls


a
ic
ed
M

atharali187.blogspot.com
  Digoxin have

11. G protein for receptors

6
"QISS & QIQ" (Kiss and Kick):

01
G-proteins and their respective receptors in alphabetical order:

-2
 G-protein Q: alpha 1 receptor,

11
 G-proteins I: alpha 2 receptor ,

20
 G-proteins S: beta 1 receptor ,

n
 G-protein S: beta 2 receptor
io
ss
&
se

 G-protein Q: M1 receptor,

 G-protein I: M2 receptor,
re

G-protein Q: M3 receptor.
nt


ce
dy

12. oral drugs forming insoluble complexes

tu

TIAPS '
ls

Read as “Tie-ups”.
a
ic
ed
M

atharali187.blogspot.com
  Tetracycline with Iron compounds

 Antacids/Phenytoin with Sucralfate

6
01
13. autoinduction

-2
Drugs that induce their own metabolism

11
Auto,Car & Rickshaw

20
Autoinduction -Carbamazepine & Rifampin

n
io
ss
14. orally ineffective or less effective drugs
se
re

"Dont put PINS inside the mouth!"

nt

 Pencillin-G
ce

 Insulin
dy

 Neostigmine
tu

 Streptomycin
ls

15. non-competitive inhibitor drugs

a
ic
ed
M

atharali187.blogspot.com
 A LIVE TIPS AD

A. acetazolamide

Live. Lovastatin

6
t. theophylline

01
I. Indomethacin

-2
P. Propyl thiouracil

11
S. Sildenafil

20
A. Aspirin

n
D. Disulfiram
io
ss
se

16. drygs metabolised by Acetylation

re

PHC IS Primary
P-Procainamide
nt

H-Hydralazine
ce

C-Clonazepam
I-INH
dy

S-Sulphonamides
P-Phenelzine
tu
lsa
ic
ed
M

atharali187.blogspot.com
 17. zero order kinetic

SWAT - Salicylate, Warfarin, Alcohol,

Theophylline
Police - Phenytoin

6
Team – Tolbutamide

01
18. LIVER ENZYME INDUCERS

-2
SB CCPR

11
20
SULFAPYRAZONE
BARBITURATES

n
CHRONIC ALCOHOL
CARBAMEZEPINE
io
ss
PHENYTOIN
RIFAMPICIN
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 19. Enzyme inducers

GPRS Cell Phone

G-Griseofulvin

6
P-Phenyton

01
R-Rifampicin
S-Smoking

-2
C-Carbamazepine

11
P-Phenobarbitone

20. acetylation drugs

20
DSHIP=DAPSONE,SULPHONAMIDE,HYDRALAZINE,INH,;;;PROC

n
AINAMIDE
io
ss
21. . Gi mediated receptors
se

MAD 2
re

Type 2 receptor of
nt

Muscarinic
ce

Alpha
Dopamine
dy
tu

Act through GPCR with Gi as Gprotein

lsa
ic
ed
M

atharali187.blogspot.com
 22. camp as second messenger

beta c amp glue lubricates so many thyroids

6
Beta- beta agonists,

01
C-CRH,calcitonin,hCG,
a-alpha2 agonist, ACTH,ADH,

-2
m-MSH,
p-PTH,

11
glue-glucagon,
Lubricates-LH,

20
somany-somatostatin,
Thyroid-TSH

n
23. TORSADES DE POINTES
io
ss
QUEEN IS SONALI, , PRIYANKA, ASIN, AMRITHA, or KAZOLE:
se

QUINIDINE
re

DISOPYRAMIDE
nt

SOTOLOL
PROCAINAMIDE
ce

ARSENIC OXIDE
AMIADARONE
dy

AZOLES
tu
lsa
ic
ed
M

atharali187.blogspot.com
 24. microsomal enzyme inhibitor

PEACOCK VALA

6
01
P: PHENYLBUTAZONE

-2
E: ERYTHROMYCIN
A: ALLOPURINOL

11
C: CIPROFLOXACIN
O: OMEPRAZOLE

20
C: CIMETIDINE
K: KETOCONAZOLE

n
VALA: VAPROATE
io
ss
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 25. Drugs with high hepatic extraction ratios

"I've pickl'd Pam" or "I pickled vamp" if you prefer.

Imipramine

6
Verapamil

01
Etomidate

-2
Propofol

11
Isoniazid
Chlorpromazine

20
Ketamine
Lidocaine
Diltiazem

n
io
ss
Propranolol
Amitriptyline
se

Morphine
re

Also might help to remember there are three induction agents -

nt

propofol/ketamine/etomidate, four antiarrhythmics -

verapamil/diltiazem/propranolol/lidocaine and five nerve-y drugs -
ce

amitriptyline/imipramine/chlorpromazine/morphine/isoniazid
(neurotoxic!)
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 26. competitive inhibition

Km is increased in Kompetitive inhibition

27. hit n run drugs

6
01
ROGI -
R- RESERPINE

-2
O-OMEPRAZOLE
G-GUANTHIDINE

11
I-INHIBITERS[MAO]

20
28. EXAMPLES OF ACTIVE DRUG PRODUCING ACTIVE
METABOLITES

n
Chief Minister ADD CIA
io
ss
trichloroethanolChlorhydrate
se

Morphine 6-glucuronideMorphine
re

AlloxanthineAllopurinol
nt

oxazepamDiazepam
ce

digoxinDigitoxin
dy

morphineCodeine
desipramineImipramine
tu

NortriptylineAmitriptyline
lsa
ic
ed
M

atharali187.blogspot.com
 29. EXAMPLES OF PRODRUG PRODUCING ACTIVE
METABOLITES

LEADS

6
Levodopa dopamine

01
Enalapril enalaprilat

-2
11
Alphamethyldopa alphamethylnorepinephrine.

20
Dipivefrine epinephrine

Sulindac sulfide metabolites

n
io
30. DRUGS METABOLISED BY METHYLATION
ss
se

Cindy Has A New Motor

C aptopril
re

H istamine
A drenaline
nt

N icotinic acid
ce

M ethyldopa
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 Ans Pharma

1. beta 1 selectibe bloker

A-BEAM

6
Acebutalol

01
Betaxolol

-2
Esmolol

11
Atenolol

20
Metprolol

n
2.uses of propranolol io
ss
se

HATE THE PAST

re

Headach
nt
ce

Angina

Tension
dy

Essential trmors
tu

Tensional headach
lsa
ic
ed
M

atharali187.blogspot.com
 Hyperthyroidism

Elevated B.P

Phobia

6
Anxiety

01
Stress

-2
Traumatic stress

11
20
3.contraindication of propranolol

n
ACID

Asthma io
ss
se

COPD

Imbalance of electrolyte
re

Diabetic mellitus
nt
ce

4. adverse affects of beta blockers

BBC Loses Viewera In Rawalpindi

dy

Bradycardia
tu
ls

Bronchospasm
a
ic
ed
M

atharali187.blogspot.com
 Lipids (increased)

Vivid dreams

Impotency

6
Reduced sensitivity to hypoglycemia

01
-2
5. non –selective beta blockers

11
PANTOP

20
Prapranolol

n
Alprenolol

Nadolol io
ss
se

Timolol

Oxprenolol
re

Pindolol
nt
ce

6. cardioselective beta blockers

dy

CaN BEAM"
tu

Celiprolol
ls


a
ic
ed
M

atharali187.blogspot.com
  Nebivolol (most selective)

 Bisoprolol, Betaxolol

 Esmolol

6
 Atenolol, Acebutolol

01
 Metoprolol

-2
7. beta blockers with instrinsic sympathetic activity (ISA)

11
Think: They "COntain Partial Agonistic Activity"

20
 Celiprolol, Oxprenolol

n
 Pindolol, Penbutolol
io
ss
 Alprenolol
se

 Acebutolol

8. receptors of heart
re
nt

2 Beautiful hearts Marry 2 Be 1"

ce

 B2 receptor (adrenergic)

M2 receptor (cholinergic) and

dy

B1 receptor (adrenergic)
tu


ls

9. morphine vs amphetamine. Pupils in overdoses

a
ic
ed
M

atharali187.blogspot.com
 MorPHINE is Fine & AmPHETamine is Fat !"

6
 Morphine overdose: pupils constricted (fine)

01
 Amphetamine overdose: pupils dilated (fat)

-2
10. anticholinergic side effects

11
20
"Know the ABCD'S of anticholinergic side effects":

n
 Anorexia

Blurry vision io
ss

se

 Constipation/ Confusion

 Dry Mouth
re

Sedation/ Stasis of urine

nt


ce

11. antimuscrinic drugs and their action

Inhibits Parasympathetic And Sweat ":

dy

 IIpratropium
tu

Pirenzepine
ls


a
ic
ed
M

atharali187.blogspot.com
  Atropine

 Scopolamine

12. edrophonium vs pyridostigmine in myasthenia gravis

6
eDrophonium is for Diagnosis

01
And pyRIDostigmine is to get RID of symptoms

-2
11
13. MOA of tacrine and edrophonium

20
n
TEA ":
io
Tacrine and Edrophonium attach only to Anionic site of
ss
enzyme,Cholinesterase(ChE)
se

( Organophosphates attach only to the estatrtic site of

re

Cholinesterase )
nt
ce

14. reversible anticholinesterases

dy
tu
ls

Car PPENDoRi ": Read as "carpentry"

a
ic
ed
M

atharali187.blogspot.com
 Reversible Anticholiesterases belonging to Carbamates are

 Physostigmine

 Pyridostigmine

6
 Edrophonium

01
 Neostigmine

-2
 Donepezil

11
 Rivastigmine

20
15. Muscarinic effects

n
SLUG BAM ": io
ss
se

 Salivation/ Secretions/ Sweating

Lacrimation
re

Urination
nt


ce

 Gastrointestinal upset

Bradycardia/ Bronchoconstriction/ Bowel movement

dy

Abdominal cramps/ Anorexia

tu


lsa
ic
ed
M

atharali187.blogspot.com
  Miosis

16. nicotinic affects

6
" MTWThF in rhythm "(days of week):

01
 Mydriasis/ Muscle cramps

-2
 Tachycardia

11
 Weakness

20
 Twitching

n
 hypertension/ hyperglycemia

Fasiculation io
ss

se

17. cholinergic affects on bowl and bladder

re

Call inergic/Cholinergic makes us attend natures call ! ":

nt
ce

ie.,Evacuation of Bowel and Bladder

dy

18. organophosphates eefects ( Cholinergic)

tu
lsa
ic
ed
M

atharali187.blogspot.com
 "If you know these, you will be LESS DUMB Choline ":

 Lacrimation

 Excitation of nicotinic synapses

6
 Salivation

01
 Sweating

-2
 Diarrhea

11
 Urination

20
 Micturition/Miosis

n
 Bronchoconstriction
io
ss
19. cholinergic agonists
se

Esters: A-MCB
re

ACh ,Methacholine ,Carbechol ,Bethanechol

nt
ce

Alkaloids: PMA

:Pilocarpine, Arecoline, Muscarine

dy
tu

20. autoreceptors
lsa
ic
ed
M

atharali187.blogspot.com
 Au to receptors ":

The' to' rhymes with 2.

So the Autoreceptors are Alpha 2 (for adrenergic pathway)
and M2 (for cholinergic pathway)

6
01
21. cholinergic receptor

-2
MuGNiL":

11
Muscarinic :G protein coupled

20
Nicotinic :Ligand gated ion channel

n
io
ss
22. botulinus toxin action
se

Think: Botulinum toxin Bottles up Acetyl choline (ACh).

re

It means, botulinum toxin blocks exocytic release of ACh

nt

from the synaptic vesicles at the neuromuscular junction

ce

leading to flaccid paralysis.

dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 23. inhibiton of choline uptake during Ach synthesis

H-I-C-Up "
Hemicholinium Inhibits Acetyl Choline Uptake

6
01
-2
24. site of acetyl choline release

11
"PreACh ":

20
Acetyl Choline ( ACh ) is released from all Pre ganglionic
fibres of ANS

n
io
ss
se

25. physostigmine vs neostigmine

re

"LMNOP":
nt

 Lipid soluble
ce

 Miotic

Natural
dy


tu

 Orally absorbed well

lsa
ic
ed
M

atharali187.blogspot.com
  Physostigmine

26. atropine use : tachycardia or bradycardia

6
A goes with B":

01
Atropine used clinically to treat Bradycardia.

-2
11
27. reserpine action

20
Reserpine depletes the Reserves of catecholamines [and

n
serotonin].
io
ss
se

28. ipratropium action

re
nt

Atropine is buried in the middle: iprAtropium, so it behaves

like Atropine.
ce
dy

29. succinylcholine uses

tu
lsa
ic
ed
M

atharali187.blogspot.com
 Succinylcholine gets Stuck to Ach receptor, then Sucks ions
in through open pore.
You Suck stuff in through a mouth-tube, and drug is used for
intubation.

6
01
30. depression causing drugs

-2
PROMS:

11
Propranolol
Reserpine

20
Oral contraceptives
Methyldopa

n
Steroids
io
ss
se

31. direct sympathomimetic catecholamine

re

DINED:
nt

Dopamine
ce

Isoproterenol
Norepinephrine
dy

Epinephrine
tu

Dobutamine
lsa
ic
ed
M

atharali187.blogspot.com
 32. Morphine: side-effects MORPHINE:
Myosis
Out of it (sedation)
Respiratory depression
Pneumonia (aspiration)

6
Hypotension

01
Infrequency (constipation, urinary retention)
Nausea

-2
Emesis

11
20
33. Bromocriptine [for USA gang members] The CRYPTS are
an LA street gang that likes to smoke DOPE.

n
BromoCRYPTine is a DOPamine agonist.

io
ss
se

34. Guanethidine: mechanism GuaNEthidine prevents NE

(norepinephrine) release.
re
nt

35.
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 Parasympathetic vs. sympathetic neurotransmitters "No
sympathy for a Pair of Aces":
Norepinephren is secreted in by the Sympathetic nervous system
while Acetylcholine is secreted in the Parasympathetic nervous
system.

6
01
36.

Morphine: effects at mu receptor PEAR:

-2
Physical dependence

11
Euphoria
Analgesia

20
Respiratory depression

n
37. io
ss
Prazocin usage Prazocin sounds like an acronym of "praszz
se

zour urine".
Therefore Prazocin used for urinary retention in BPH.
re
nt

38.
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 Beta blockers with CYP2D6 polymorphic metabolism "I Met
Tim Carver, the metabolic polymorph":
· The following beta blockers require dose adjustment due to CYP2D6
polymorphic
metabolism:

6
Metoprolol

01
Timolol
Carvedilol

-2
(in patients with lower or higher than normal CYP2D6 activity)

11
20
39.

alpha blockers uses

n
harry potter sees 2 BP and PIPE io
ss
se

harry=hypertension
potter=pheochromocytoma
re

sees2= secondary shock

BP= benign hypertrophy of prostate
nt

PIPE= penile impotence

ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 40. Parasympathetic action

Parasympathetic action
@SLUDD + 3D’s
Salivation

6
Lacrimation

01
Urination (so Anticholinergics cause urinary retension)
Digestion

-2
Defecation

11
3 important Decreases
Decrease in heart rate and contractility

20
Decrease in pupil size i.e. Miosis
Decrease in airway size (so anticholinergics given in COPD)

n
io
ss
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 41. Physostigmine vs. neostigmine

@ LMNOP:
Lipid soluble
Miotic

6
Natural

01
Orally absorbed well
Physostigmine

-2
• Neostigmine, on the contrary, is:

11
Water soluble
Used in myesthenia gravis

20
Synthetic
Poor oral absorption

n
42. cholinergic classification io
ss
se

MAP of ABC
M= muscarine
re

A= arecoline
P= pilocarpine
nt

of
ce

A= acetylcholine
B= bethanechol
dy

C= carbachol
tu
lsa
ic
ed
M

atharali187.blogspot.com
 43. reversible anticholinesterase

NEW GALLANT DON ED TAKES REVERSE SPY

NEW= neostigmine

6
GALLANT= galantamine

01
DON= donepezil
ED= edrophonium

-2
TAKES= tacrine

11
REVERSE= rivastigmine
SPY= pyhsiostigmine/ pyridostigmine

20
( gallant means brave)

n
io
ss
44. alpha 1 agonists
se

M.MNOP
re

M-methoxamine
nt

M-midodrine
N-naphazoline
ce

O-oxymetazoline
P-phneylephrine
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 45. beta-1 selective blocker

NAME-ABC

N-nebivolol

6
A-atenolol

01
M-metoprolol*
E-esmolol

-2
11
A-acebutanolol**
B-betaxolol

20
C-celiprolol**

*drug having membrane stabilising activity also.

n
io
ss
** drug having membrane stabilising as well as intrinsic
sympathomimic action
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 46 Cardioselective Beta Blockers

New Beta Blockers Acting Exclusively At Myo Cardium

Nebivolol(most cardioselective)
Betaxolol

6
Bisoprolol

01
Atenolol
Esmolol

-2
Acebutolol

11
Metoprolol
Celiprolol

20
n
47. cholinergic crisi
io
ss
DUMBELSS
se

Diarrhoea
Urination
re

Miosis
nt

Bronchospasm
Excitation cns and neuromuscular
ce

Lacrimation
Sweating
dy

Salivation
tu
lsa
ic
ed
M

atharali187.blogspot.com
 48. lipid insoluble b blocker

Not soluble a b c

Nadolol

6
Sotalol

01
Atenolo acebutolol
Betaxolol bisoprolol

-2
Celiprolol

11
49. CARDIOSELECTIVE B BLOCKER

20
ameba

n
ATENOLOL
METOPROLOL io
ss
ESMOLOL
se

BETAXOLOL
ACEBUTALOL
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 50. reversible Anticholinestrases

ANTI- ANTICHOLINESTERASE
RaGING -

6
REVERSE,RIVASTIGMINE POLICE- PHYSIOSTAGMINE

01
TAKE -TACRINE

-2
GREAT -GALANTAMINE

11
DON –DONEPEZIL

20
n
io
ss
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 51. Uses of beta blockers

HM HAT CM CD PAGE
H-Hypertension
M-Myoardial infarction

6
H-Hypertrophy obstructive cardiomyopathy

01
A-Angina pectoris
T-Thyrotoxicosis

-2
C-Congestive Heart failure

11
M-Migraine
C-Cardiac arrythmias

20
D-Dissecting aortic aneurysm
P-Pheochromocytoma
A-Anxiety

n
G-Glaucoma
io
ss
E-Essential tremors
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 52. Effects of Beta blockers on Heart and Bloodvessels

SORAB got CHF

S- Prolong Systole
O- Dec Oxygen consumption

6
R- Dec Refractory period of myocytes

01
A- Dec automaticity
B- Dec SBP nd DBP on Chr Administration

-2
C- Dec Cardiac output, Cardiac work & total coronary blood flow

11
H- Dec Heart rate
F- Dec Force of contraction

20
53. Beta blockers contra in renal failure

n
"ANS"
io
ss
Atenolol
se

Nadolol
Sotalol
re

54. sympathomimetic hypertensives

nt

Many- Mephenteramine
ce

People- Phenylephrine
Never- Noradrenaline
dy

Marry- Methoxamine
tu
lsa
ic
ed
M

atharali187.blogspot.com
 55. zero order kinetics-ITS AWESOM

text WHATT are these drugs.

W- warfarin

6
H- hydantoin

01
A- aspirin
T- tolbutamide

-2
T- theophylline

11
56. ADRENALIN

20
ADRENALIN USES
ABC HIL

n
A-ANAPHYLACTIC SHOCK
B-BRONCHOSPASM io
ss
C-CARDIAC ARREST
se

H-HEAMOSTATIC AGENT
I-INSULIN INHIBITION
re

L-LOCAL ANAESTHETIC
nt

57. AGONISTS OF DOPAMINE

ce

B-BROMOCRIPTINE
A-ANTICHOLINERGICS(CENTRAL)
dy

L-LEVODOPA
tu
lsa
ic
ed
M

atharali187.blogspot.com
 CVS PHARMA

1. aspirin side affects

"ASPIRIN"

6
 Asthma

01
 Salicylism

-2
 Peptic ulcer / Premature closure of PDA

11
 Intestinal blood loss

20
 Reye's syndrome

n
 Idiosyncracy

Noise (tinnitus) io
ss

se

2. hypertension management

"ABCD"
re

ACE inhibitors/Angiotensin receptor blockers

nt


ce

 Beta blockers

 Calcium channel blockers

dy

 Diuretics
tu

3. amiodarone : adverse affects

lsa
ic
ed
M

atharali187.blogspot.com
 Plz Check PFT, LFT, TFT "

 Plz- Photosensitivity, Pigmentation

 Check for Corneal deposits

6
 PFT- Pulmonary fibrosis

01
 LFT- Liver damage (pseudoalcoholic liver injury)

-2
 TFT- Thyroid dysfunction

11
4. antihypertensive : contraindicated in pregnancy

20
DARSAN '

n
 Diuretics
io
ss
 Angiotensin I antagonists
se

 Reserpine

Sodium nitroprusside
re


nt

 ACE inhibitors
ce

 Non selective β blockers

5. antiarrythmic drugs: clases

dy

" i' M BAC in rhythm ":

tu
lsa
ic
ed
M

atharali187.blogspot.com
 I.Membrane stabilizing agents (Na channel blockers)
II.Beta blockers (Antiadrenergic agents)
III.Agents widening AP
IV.Calcium channel blockers

6
01
6. receptors of heart

-2
11
"2 Beautiful hearts Marry 2 Be 1"

20
 B2 receptor (adrenergic)

M2 receptor (cholinergic) and

n


B1 receptor (adrenergic) io
ss

se

7. patent ductus arteriosus treatment

Come IN and Close the Door":

re
nt

INdomethacin is used to Close the PDA.

ce

8. ca ++ channel blocker:uses

Ca++ MASH:
dy

Cerebral vasospasm/ CHF

tu


lsa
ic
ed
M

atharali187.blogspot.com
  angina

 Migraine

 Atrial flutter, fibrillation

6
 Supraventricular tachycardia

01
 Hypertension

-2
9.   > Captopril (an ACE inhibitor): side effects CAPTOPRIL:

11
Cough
Angioedema/ Agranulocystosis

20
Proteinuria/ Potassium excess
Taste changes

n
Orthostatic hypotension
io
ss
Pregnancy contraindication/ Pancreatitis/ Pressure drop (first dose 
hypertension)
se

Renal failure (and renal artery stenosis contraindication)/ Rash
Indomethacin inhibition
re

Leukopenia/ Liver toxicity
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 10.  > Warfarin: metabolism SLOW:
∙ Has a slow onset of action.
∙ A quicK Vitamin K antagonist, though.
Small lipid­soluble molecule
Liver: site of action

6
01
Oral route of administration.
Warfarin

-2
11.  > Amiodarone: action, side effects 6 P's:

11
Prolongs action potential duration
Photosensitivity

20
Pigmentation of skin
Peripheral neuropathy

n
Pulmonary alveolitis and fibrosis
io
ss
Peripheral conversion of T4 to T3 is inhibited ­> hypothyroidism
se

12. > Clopidogrel: use CLOPIdogrel is a drug that prevents
CLots, an Oral Platelet Inhibitor (OP
re
nt

13.  > Warfarin: action, monitoring WePT:
ce

Warfarin works on the extrinsic pathway and is monitored by PT.
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 14.  Enoxaprin (prototype low molecular weight heparin): action, 
monitoring EnoXaprin only acts on factor Xa.
Monitor Xa concentration, rather than APTT.

6
01
14.  > Thrombolytic agents USA:
Urokinase

-2
Streptokinase
Alteplase (tPA)

11
20
15.  > Antiarrhythmics: classification I to IV MBA College

n
∙ In order of class I to IV:
Membrane stabilizers (class I) io
ss
Beta blockers
se

Action potential widening agents
Calcium channel blockers
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 16.  > HMG­CoA reductase inhibitors (statins): side effects, 
contraindications, interactions HMG­CoA:
∙ Side effects:
Hepatotoxicity
Myositis [aka rhabdomyolysis]

6
01
∙ Contraindications:
Girl during pregnancy/ Growing children

-2
∙ Interactions:
Coumarin/ Cyclosporine

11
20
17.  > Antiarrhythmics: class III members BIAS:

n
Bretylium
Ibutilide io
ss
Amiodarone
se

Sotalol
re
nt

18.  > ACEI: contraindictions PARK:
Pregnancy
ce

Allergy
Renal artery stenosis
dy

K increase (hyperkalemia)
tu
lsa
ic
ed
M

atharali187.blogspot.com
 19. > Endotrachial tube deliverable drugs O NAVEL:
Oxygen
Naloxone
Atropine
Ventolin (albuterol)

6
01
Epinephrine
Lidocaine

-2
∙ If you can't get IV access established, and have necessity to 
administer resuscitative meds, remember you have the airway and 

11
can give the above drugs.

20
∙ Drug delivery is enhanced if diluted with 10cc NS and rapid 
introduced for aeresolization.

n
∙ Alternatively, bare bone version is ALE, as above.
io
ss
se

20. SVT Causes SNAP
Sinus tachy, nodal tachy, a fib, paroxysmal atrial tachy
re
nt

21.  Arrhythmias
ce

ARHYTHMIAL 4PC
dy

Atrial Myxoma
tu

Rh heart dis
lsa
ic
ed
M

atharali187.blogspot.com
  Hypertension

 THyrotoxicosis

Mitral valve dis

6
 IHD,

01
Alcohol

-2
Pneumonia / PE / Pericardial eff, cardiomyopathy

11
20
22. > Atrial Fibrillation

n
ARITHMATIC
io
ss
Alcohol
se

Rh fever
re

 IHD
nt

 Thyrotoxicosis
ce

Hypertension
dy

 Mitral stenosis / MI / Myxoma
(atrial)
tu
ls

ASD
a
ic
ed
M

atharali187.blogspot.com
 Toxins,

Idiopathic/Infective endocarditis

Cardiomyopathy/Constrictive pericarditis

6
01
-2
23.  Sino­atrial node: innervations

11
Sympathetic acts on Sodium channels (SS).

20
Parasympathetic acts on Potassium channels (PS).

n
io
ss
24.  > Supraventricular tachycardia: treatment ABCDE:
Adenosine
se

Beta­blocker
Calcium channel antagonist
re

Digoxin
nt

Excitation (vagal stimulation)
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 25.  > Ventricular tachycardia: treatment LAMB:
Lidocaine
Amiodarone
Mexiltene/ Magnesium
Beta­blocker

6
01
-2
11
20
n
io
ss
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 26. > Sinus bradycardia: aetiology "SINUS BRADICARDIA" (sinus 
bradycardia):
Sleep
Infections (myocarditis)
Neap thyroid (hypothyroid)

6
01
Unconsciousness (vasovagal syncope)
Subnormal temperatures (hypothermia)

-2
Biliary obstruction
Raised CO2 (hypercapnia)

11
Acidosis

20
Deficient blood sugar (hypoglycemia)
Imbalance of electrolytes

n
Cushing's reflex (raised ICP)
Aging io
ss
Rx (drugs, such as high­dose atropine)
se

Deep anaesthesia
Ischemic heart disease
re

Athletes
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 27. > Atrial fibrillation: causes PIRATES:
Pulmonary: PE, COPD
Iatrogenic
Rheumatic heart: mirtral regurgitation
Atherosclerotic: MI, CAD

6
01
Thyroid: hyperthyroid
Endocarditis

-2
Sick sinus syndrome

11
20
28.  > Atrial fibrillation: management ABCD:
Anti­coagulate

n
Beta­block to control rate
Cardiovert io
ss
Digoxin
se
re

29.  > Atrial fibrillation: management ABCD:
nt

Anti­coagulate
Beta­block to control rate
ce

Cardiovert
Digoxin
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 30. > Sinus tachycardia TACH FEVER:
Tamponade/ Thyrotoxicosis
Anemia
CHF
Hypotension

6
01
Fever
Excrutiating pain

-2
Volume depletion
Exercise

11
Rx (Theo, Dopa, Epi, etc)

20
n
31.  Vfib/Vtach drugs used according to 
ACLS "Every Little Boy Must Pray": io
ss
Epinephrine
se

Lidocaine
Bretylium
re

Magsulfate
nt

Procainamide
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 32. > Ventricular fibrillation: treatment "Shock, Shock, Shock, 
Everybody Shock, Little Shock, Big Shock, Momma Shock, Poppa 
Shock":
Shock= Defibrillate
Everybody= Epinephine

6
Little= Lidocaine

01
Big= Bretylium

-2
Momma= MgSO4
Poppa= Pocainamide

11
20
n
io
ss
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 33. > Atrial fibrillation: causes of new onset THE ATRIAL FIBS:
Thyroid
Hypothermia
Embolism (P.E.)
Alcohol

6
01
Trauma (cardiac contusion)
Recent surgery (post CABG)

-2
Ischemia
Atrial enlargement

11
Lone or idiopathic

20
Fever, anemia, high­output states
Infarct

n
Bad valves (mitral stenosis)
io
Stimulants (cocaine, theo, amphet, caffeine)
ss
se
re

34. 
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 > PEA/Asystole (ACLS): etiology ITCHPAD:
Infarction
Tension pneumothorax
Cardiac tamponade
Hypovolemia/ Hypothermia/ Hypo­, Hyperkalemia/ Hypomagnesmia/ 

6
01
Hypoxemia
Pulmonary embolism

-2
Acidosis
Drug overdose

11
20
35. > Hypertension: secondary hypertension causes CHAPS:

n
Cushing's syndrome
io
Hyperaldosteronism [aka Conn's syndrome]
ss
Aorta coarctation
se

Phaeochromocytoma
Stenosis of renal arteries
re

∙ Note: only 5% of hypertension cases are secondary, rest are primary
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 36. > Preeclampsia: classic triad PREeclampsia:
Proteinuria
Rising blood pressure
Edema

6
01
37. > Postural Hypotension

-2
HANDI

11
Hypovolaemia / hypopituitarism,

20
Addisons

n
Neuropathy (autonomic)
io
ss
 Drugs (vasodilators /TCADs, diuretics, antipsychotics),
se

 Idiopathic
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 38. > Deep venous thrombosis: genetic causes ALASCA:
Antithrombin III
Leiden (Factor V)
APC (Activated Protein C)
S­protein deficiency

6
01
C­protein deficiency
Antiphospholipid antibody

-2
11
39.  > Deep venous thrombosis: diagnosis DVT:

20
Dilated superficial veins/ Discoloration/ Doppler ultrasound
Venography is gold standard

n
Tenderness of Thigh and calf
io
ss
se

40. > Virchow's triad (venous thrombosis) "VIRchow":
Vascular trauma
re

Increased coagulability
nt

Reduced blood flow (stasis)
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 41. > Myocardial infarct, complications ABCDE x2
Arrhythmias / Aneurysm
Bradycardia / ↓BP
Cardiac failure / cardiac tamponade
Dresslers / Death!

6
01
Embolism / Extra (VSD, pap muscle rupture)

-2
42. Lines of treatment of pulmonary oedema:

11
 DOLMA

20
Digoxin, Oxygen, Lasix, Morfine, Aminophylline. (Dolma is a very 

n
famous food in the middle east.)
io
ss
43. > M.O.N.A
“MONA” treatment for acute MI.
se

Morphine, Oxygen, Nitrate, Aspirin
re
nt
ce

44. > Coronary artery bypass graft: indications DUST:
Depressed ventricular function
dy

Unstable angina
tu

Stenosis of the left main stem
Triple vessel disease
lsa
ic
ed
M

atharali187.blogspot.com
 45.

> Acute Coronary Syndrome: initial treatment ABCD:
Aspirin

6
01
Beta blocker
Coagulation (anticoagulation with heparin/LMW Heparin)

-2
Double product control (decrease heart rate and blood pressure)

11
20
46.

> MI: therapeutic treatment "O BATMAN!":

n
Oxygen
io
ss
Beta blocker
ASA
se

Thrombolytics (eg heparin)
Morphine
re

Ace prn
nt

Nitroglycerin
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 47. > Atherosclerosis risk factors "You're a SAD BET with these 
risk factors":
Sex: male
Age: middle­aged, elderly
Diabetes mellitus

6
01
BP high: hypertension
Elevated cholesterol

-2
Tobacco

11
20
48.

> Thrombus: possible fates DOPE:

n
Dissolution
io
ss
Organization & repair
Propagation
se

Embolization
re

49.
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 > Cardiovascular risk factors FLASH BODIES:
Family history
Lipids
Age
Sex

6
01
Homocystinaemia
Blood pressure

-2
Obesity
Diabetes mellitus

11
Inflammation (raised CRP)/ Increased thrombosis

20
Exercise
Smoking

n
io
50.  MI: immediate treatment DOGASH:
ss
Diamorphine
Oxygen
se

GTN spray
re

Asprin 300mg
Streptokinase
nt

Heparin
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 51. Centrally acting anti-hypertensives

M - Methyld dopa

R - Reserpine

6
01
C - Clonidine

-2
P – Propranolol

11
20
52.

AMIODARONE - IMPORTANT SIDE EFFECTS

n
PCT - PROXIMAL CONVULATING TUBULE io
ss
se

P - PULMONARY FIBROSIS
C- CORNEAL MICRODEPOSITS
re

T- THROID DISORDERS (hypo/hyperthyroidism)

nt
ce

53. diuretic decreases calcium

dy

which diuretic loses calcium in urine..

LOOPS LOSE CALCIUM
tu
lsa
ic
ed
M

atharali187.blogspot.com
 54. Side Effects of Aspirin

ASPIRIN
A: Allergy like reactions e.g. Urticaria
S: susceptibility to bleeding

6
P: Peptic ulcer

01
I: Idiosyncratic reactions
R: Reye's syndrome

-2
I: rInging in the ears(tinnitus)

11
N: Nephropathy

20
55. Side Effects of Thiazide Diuretics

n
Mnemonic : HYPER GLUC
io
ss
Hyper = Increased
se

G = Glucose
re

L = Light-headedness (orthostatic hypotension/ low vol/ low sodium)

nt

U = Uricemia
C = Calcemia
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 56. Anti-hypertensives used in emergencies

Saurav Ganguly HELP

S-sodium nitroprusside
G-Glyceryltrinitrate

6
H-hydralazine

01
E-esmolol
L-labetalol

-2
P-phentolamine

11
20
57. anti-hypertensives giving in pregnancy

n
anti-hypertensives given in pregnancy -3Cs -Ca channel
io
blocker,cardioselective b-blocker,central sympatholytic-clonidine.
ss
se

58. Nitric oxide donors

re

Highly Pro Nitric

nt
ce

H:Hydralazine
P:Propofol
dy

N:Nebivolol
tu

And the rest :Na nitroprusside,Organic nitrates,Nitrites.

lsa
ic
ed
M

atharali187.blogspot.com
 59. heparin

H=HYPERSENSITIVITY & hyperkalemia

6
E=excessive beeding

01
P=PROLONG APTT
A=ALOPECIA

-2
R=REDUCED PLATELET & BONE MASS
i.e.thrombocytopenia osteoporosis

11
I=i.v. route
N=aNtagonise by protamine sulphate

20
n
60. digitalis
io
ss
Digitalis toxicity is aggravated by KOMAR (READ IT AS KUMAR) of
se

CaLIFORNIA
re

KOM-hypoka,hypoxe,hypomag
Advance age
nt

Reanal insufficiency
ce

California in block letters suggest hyperCALCEMIA

dy

KEEP ON REVISING...
tu
lsa
ic
ed
M

atharali187.blogspot.com
 61. drugs contraindicated in heart failure

Napolean _Narcotics including Opioids

Bonaparte _Benzodiazepines
Says_Salicylates

6
Hello_Hypnotics

01
To _Tranquilizers
Don_Diuretics

-2
11
62. fibrinolytics

20
STUART

n
S-STREPTOKINASE
io
ss
T-TENECTEPLASE
U-UROKINASE
se

A-ALTEPLASE
R-RETEPLASE
re

t
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 63. Side effects of Spironolactone

I May Have Got Additional Potassium.

I=Impotence

6
M=Menstrual irregularities

01
H=Hirsuitism
G=Gynaecomastia

-2
A=Acidosis

11
P=Peptic ulcer(aggravates)

20
And last but not the least is the pnemonic itself states the main side-
effect=Hyperkalemia

n
64. antiarrythmic class I A
io
ss
Queen Proclaims Diso'sPyramid
se

QUINIDINE
PROCAINAMIDE
re

DISOPYRAMIDE
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 65. antiarrythmic class I B

IBuy Lido's Mexican Toffees

IB=

6
Lidocaine

01
Mexiletene
Tocainide

-2
11
66. antiarrythmic class I C

20
Fleeting Programme Maker
Flecainide

n
Propafenone
Moricizine
io
ss
se

67. K sparing diuretscs

re

EAST
nt

Epleranone
ce

Amiloride
dy

Spironolactone
tu

Triameterene
lsa
ic
ed
M

atharali187.blogspot.com
 Chemo-Pharma

6
01
1. Antibiotics contraindicated during pregnancy

-2
MCAT:

11
Metronidazole

20
Chloramphenicol

Aminoglycoside

n
Tetracycline io
ss
se

2. Etoposide: action, indications, side effect

re

"eTOPoside":
nt

· Action:
ce

Inhibits TOPoisomerase II
dy

· Indications:
tu

Testicular carcinoma
ls

Oat cell carcinoma of lung

a
ic
ed
M

atharali187.blogspot.com
 Prostate carcinoma

· Side effect:

Affects TOP of your head, causing alopecia

6
3. Bleomycin: action

01
"Bleo-Mycin Blows My DNA to bits":

-2
Bleomycin works by fragmenting DNA (blowing it to bits).

11
My DNA signals that its used for cancer (targeting self cells)

20
4. major side effects of isoniazid

n
io
isoniazid or isonicotinic acid hydrazide(INH)
ss
I-INSANITY(psychosis)
se

N-NEURITIS(peripheral neuritis)
H-HEPATITIS
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 5. antipseudomonal aminoglycosides

a small one. antipseudomonal aminoglycosides:

mnemonic: TAG

6
01
T: tobramycin

-2
A: amikacin

11
G: gentamycin

20
n
6. antifungals-DOCs
io
ss
amphotericin B- SAM (name)
S-Sporotrichosis
se

A-Actinomycosis
M-Mucormycosis
re

Itraconazole PChB (phy,chem,bio)

nt

P-Paracoccididomycosis
Ch-chromomycosis
ce

B-Blastomycosis
Ampho+5FC DC & CC (jingle)
dy

DC-dissem. candidiasis
tu

CC-cryptococcosis
amph/itr HP-histoplasmosis
lsa
ic
ed
M

atharali187.blogspot.com
 7. METRONIDAZOLE-SPECTRUM OF ACTION

SPECTRUM OF ACTION

6
A-Amoebiasis

01
B-Bacteroides fragilis
C-Clostridium perfringens

-2
D-Dracunculus medinensis
E-Pseudomembranus Enterocolitis

11
F-Fusobacterium
G-Giardiasis

20
H-Helicobacter Pylori
S-Anaerobic Streptococci

n
T-Trichomonas
io
ss
8. Rifampin
se

4R's
RNA polymerase inhibitor
re

Revs up Microsomal P450

nt

Red/Orange body fluids

Rapid Resistance if used alone
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 9. Uses of cotrimoxazole

Utre: Urinary Tract Infections

Reti: Respiratory tract infections
par

6
Tight: Typhoid

01
Body: Bacterial Diarrhoeas & Dysentery
lekar, jab

-2
Chance: Chancroid

11
Gine: Granuloma Inguinale
Ap: Agranulocytosis patients

20
PC: Pneumocystis carinii
par

n
10. s/e of tetracyclines
io
ss
KAPIL DeV to BAT
se

K - Kidney damage
A - Antianabolic effect
re

P - Photoxicity
I - Increased intracranial pressure
nt

L - Liver damage
ce

De - Diabetes insipidus
V - Vestibular toxicity
dy

to
BAT - Bones And Teeth
tu
lsa
ic
ed
M

atharali187.blogspot.com
 11. Adverse effects of chloramphenicol

Adverse effects of Chloramphenicol-

BIG Super Hypersensitivity

6
01
B- Bone marrow depression

-2
I- Irritative effects like nausea, vomiting, diarrhoea, pain on injection

11
G- Gray baby syndrome

20
Super- super infections

n
io
Hypersensitivity reactions like rashes, fever, angioedema
ss
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 12. uses of tetracyclines

Uses of tetracyclines - (used as 1st choice drugs in- )

V Are B.R. Chopra Productions

6
V -Venereal diseases (lymphogranuloma venerum and granuloma

01
inguinale)

-2
Are- Atypical pneumonia due to mycoplasma pneumoniae

11
B - brucellosis tretment

20
R- Rickettsial infections, Relapsing fever

n
Chopra- Cholera
io
ss
Productions- Plague
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 13. bactericidal drugs

I M Bactericidal Because A Very Quiet Person is Rarely Protected

Isoniazid

6
Metronidazole

01
Beta lactams
Bacitracin

-2
Aminogycosides

11
Vancomycin
Quinolones

20
Pyrazinamide
Rifampin
Polymyxin

n
io
ss
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 14. bacteriostatic drugs

Static Causes Non Total Or Non Complete Though Massive

Elimination

6
Sulfonamides

01
Chloramphenicol
Nitrofurantoin

-2
Tetracyclin

11
Oxazolidinon
Novobiocin

20
Clindamycin
Trimethoprim
Macrolide

n
Ethambutol
io
ss
se

15. antibiotics c/I in pregnancy

re

SAFETY
nt

S - SULPHONAMIDES
A - AMINOGLYCOSIDES
ce

F - FQs
E - ERYTHROMYCIN ESTOLATE
dy

T - TETRACYCLIN
tu

Y – clindamYcin
lsa
ic
ed
M

atharali187.blogspot.com
 16.antitubeculosis drugs

SPIRE

S..............STREPTOMYCIN

6
P...............PYRIZINAMIDE

01
I...............ISONIAZIDE
R,.............RIFAMPICIN

-2
E...............ETHAMBUTOL

11
17. macrolides

20
RACE
R-roxithromycin

n
A-azitromycin
C-clarithromycin
io
ss
E-erythromycin.
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 18. Antitubercular drugs. K.D.Tripathi

¤First line drugs.

(PRIEST)
Pyrazinamide

6
Rifampin

01
Isoniazid
Etambutol

-2
STreptomycin

11
¤second line drugs
(Please TAKE Carbon Copy)

20
Paraamino salicylic acid
Thiacetazone
Amikacin

n
Kanamycin
io
ss
Ethinamide
Capreomycine
se

Cycloserine
¤Newer drugs.
re

(CAR Of Century)
nt

Ciprofloxacin
Azithromycin
ce

Rifabutin
Ofloxacin
dy

Clarithromycin
tu
lsa
ic
ed
M

atharali187.blogspot.com
 19. anti psedomonal drugs

Amin Beta Pseudo Polyp Roq!

6
Amin-Aminoglycosides

01
Beta-beta lactams

-2
11
Pseudo-pseudomonas

20
Roq-fluoROQuinolones

n
20. ADR of Interferons
io
ss
MY FAITH is NEUROTOXIC
se

MY-MYelosuppression
F-Flu like symptoms
re

A-Alopecia
nt

I-Interstitial nephritis
T-Thyroiditis
ce

H-Hepatotoxicity
is
dy

NEUROTOXIC
tu
lsa
ic
ed
M

atharali187.blogspot.com
 21. Penicillin DOC in

"P.M.(Prime Minister) Pass List of An Strict Act of Superfast Train's Tt."

P-Pneumococci
M-Meningococcal meningitis

6
Pass-Pasturella multocida

01
List-Listeria
An-Anthrax

-2
Strict-Streptococci

11
Act-Actinomyces
Superfast-Syphillis

20
Train's-Trench fever
Tt-Tetanus

n
io
ss
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 22. Anticancer drugs

From K.D. Tripathy

ALKYLATING AGENTS: TANEN / NEAT N
Triazine: Dacarbazine

6
Alkyl Sulfonate: Busulfan

01
Nitrosoureas: Carmustine
Lomustine

-2
Ethylenimine: Thio- TEPA

11
Nitrogen Mustards: MCI CM
Mechlorethamine

20
Cyclophosphamide
Ifosfamide
Chlorambucil

n
Melphalan
io
ss
VECTA
Vinca Alkaloids: Vincristine
se

Vinblastine
Epipodophyllotoxin: Etoposide
re

Camptothecin Analogues: Irinotecan

nt

Topotecan
Taxanes: Paclitaxel
ce

Docetaxel
Anti metabolites:
dy

Folate Antagonist: Methotrexate

Purine Antagonist: F ATM
tu

Fludarabine
ls

Azathioprine
6- Thioguanine
a

6- Mercaptopurine
ic

Pyrimidine Antagonist: 5- FU
ed

Cytarabine
M

atharali187.blogspot.com
 Antibiotics: ADD MMB/ DMD MBA
Actinomycin D
Doxorubicin
Daunorubicin
Mitomycin C

6
Mitoxantrone

01
Bleomycin
Misc: HPCL I

-2
Hydroxyurea

11
Procarbazine
Cisplatin

20
Carboplatin
L- Asparaginase
Imatinib

n
Lastly Drugs altering Hormonal Milieu
io
ss
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 23. erythromycin uses

it is used against..
' pure dairy white chocolate'
pure- pneumonia

6
dairy- diphtheria

01
white- whooping cough
chocolate- chancroid

-2
24. ANTI-MALARIAL DRUGS

11
"A Q can B D Answer Surely bt Teacher make's Answer NonSense"

20
4-aminoquinolines

n
quinoline-methanol
cinchona alkaloids io
ss
biguanades
se

diaminopyramidines
8-aminoquinoline
re

sulfonamides nd sulfone
tetracyclines
nt

amino alcohols
ce

naphthoquinone
sesquiterpine lactones
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 25. SULPHONAMIDES

SULPHONAMIDES
S=Steven johnson syndrome
U=urtecaria

6
L=Leukopenia

01
P=Photo-sensitivity
H=Haemolytic anemia/Hepatitis

-2
O=Oobstruction of urinary tract

11
N=Nausea,Vomiting,diarrhea?Nephritis
A=Agranulocystosis

20
M=Malaise/Megaloblastic aneamia
I=Increase risk of Kernicterus in new born
D=Depression?drug fever

n
E+Eosinophilia
io
ss
S=Skin rashes
se

26. antibiotic action on protien synthesis

re

Buy at 30 sell at 50
nt

At aminogycoside tetracycline 30 s ribosome

ce

Sell streptomycin erythromycin lincosamide linasolide 50 s ribosome

dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 27. Doxycycline DOC

RELY on RICH doxy

RElapsing fever
LYmes disease

6
RIkketsial infections

01
CHlamydial infections

-2
conditions where Doxycycline is drug of choice

11
28. penicillinase resistant penicillin

20
C - cloxacillin

n
O - oxacillin
io
ss
N - nafcillin
se

D - dicloxacillin
re

O
nt
ce

M – mezlocillin
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 29. Oncology (Monoclonal antibodies in chemotherapy)

BAC TIGeR

B-BeVacizumab

6
A-Alemtuzumab

01
C-Cetuximab

-2
T-Trastuzumab

11
I-Ibrituximab
G-Gemtuzumab

20
R-Rituximab

30. cepholo against bacteroids

n
T drugs against bacteroids io
ss
CefaTetan
se

CefameTazole
CefaxiTin
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 31. DAPTOMYCIN

DAPTOMYCIN
D-depolarisation ( MOA)
A-all infections

6
P-pulmonary surfactant is it's inhibitor

01
TO-TO be avoided in pneumonia
MY- Myopathy

-2
CIN-CI dal (bactericidal )

11
32. MRSA

20
Drugs effective in MRSA
Victoria Terminal Se Lekar Dadri Root is Closed

n
Vancomycin
Teicoplanin io
ss
Streptogramins
se

Linezolide
Daptomycine
re

Cotrimoxazole
Rifampicin
nt
ce

33. AMPHTERICIN B
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 A nemia
M uscle spasms
P hlebitis
H eadaches/hypotension/hypokalemia
T hrombocytopenia

6
E mesis, encephalopathy

01
R espiratory strida
I ncreased temperature (fever)

-2
C hills

11
I mmediate hypersensitivity (anaphylaxis)
N ephrotoxicity—important!

20
B ronchospasm

n
34.NNRTIs (Edited, New)
io
ss
Isha Virani never remembers to pin up her dress
se

Isha virani is for ifavirenz,

re

never remembers is for nevirapine

nt

d in the dress means delaviridine.

ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 35. NRTIs (New, edited)

Its for remembering NRTIs category drugs,

Abaca's (Abaca is an african negro man! just to remember) African

6
Zoo for Ass , Lambs and Dianosaurs .

01
Abaca is for abacavir!

-2
Zoo is for Zalcitabine!

11
Ass that is "a" is for "azt" and "S" is for stavudine!
Lambs is for Lamivudine!

20
Dianosaures is for Didanosine

n
36. ANTIVIRAL drugs are:
io
ss
A Acyclovir | in herpes infection except
se

N Nevirapine & Nelfinavir | Nevirapine & Nelfinavir

re

T Trifluridine | which are used in HIV

nt

I Idoxuridine | infection
ce

V Vidarabine |
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 I Indinavir | Protease |

R Ritonavir | inhibitors |

6
| in HIV

01
| infection

-2
A AZT or Zidovidine | Reverse transcriptase |

11
L Lamivudine | inhibitors |

20
37. Uses of Fluoroquinolones (shared by Gajanan Taywade)

n
{3G SPECTRUM CT} io
ss
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 3G: Gonorrhoea, Gastroenteritis & Gram -ve Infections
S: Septicemia
P: Prophylaxis
E: Enterocolitis
C: Chancroid

6
T: Typhoid

01
R: RTI
U: UTI

-2
M: Meningitis

11
C: Conjunctivitis
T: Tuberculosis

20
38. RIBAvirin:

n
RSV io
ss
se

Influenza B

Arenaviruses (Lassa, Bolivian, etc.)

re
nt

39. Cephalosporins are active against many bacteria, but these

ce

special bacteria make them CALM (Ineffective)

dy

remembr: CALM
tu

C=CLAUSTRIDIUM
lsa
ic
ed
M

atharali187.blogspot.com
 A=ACTIVE ENTEROCOCCI
L=LISTERIA MONOCYTOGENES
M= MRSA (METHICILLIN RESISTENT STAPHYLOCOCCI

6
01
40. antihelmenthic

-2
for tapeworm

11
DIFFICULT - DISCHLORPHEN

20
QUESTION - QUINACRINE
NOT - NICLOSAMIDE
ANSWERED – ASPIDIUM

n
41. antihelminthic io
ss
se

for roundworm
PRESS -PIPERAZINE
THE -THIABENDAZOLE
re

HANDLE - HEXYLRESORCINOL
nt

OF - OIL OF CHENOPODIUM
ce

SIDE - SENTONIN
DOOR – DIETHYLCARBAMAZINE
dy
tu

42. antibiotics,atntiviral and antifungal causing nephrotoxicity

lsa
ic
ed
M

atharali187.blogspot.com
 Mnemonic: SIGMA CAT FAG

6
Sulfonamides

01
Indinavir

-2
Ganciclovir

11
Metronidazole

20
Acyclovir

n
Cidofovir io
ss
Aminoglycosides
se

Tetracyclines
re
nt

Foscarnet
ce

Amphoterican B
dy

Glycopeptides (Vancomycin)
tu
ls

44.antibiotics inhibiting 30s vs 50s

a
ic
ed
M

atharali187.blogspot.com
 buy AT 30, CCELL at 50

30S:
Aminoglycosides (gentamicin, amikacin, streptogramin, tobramycin)
[bacteriocidal]

6
Tetracyclines [bacteriostatic]

01
50S:

-2
Chloramphenicol [bacteriostatic]

11
Clindamycin [bacteriostatic]
Erythromycin [bacteriostatic]

20
Lincomycin [bacteriostatic]
Linezolid [variable]

n
io
ss
45.target of first generation cephalosporins
se

PEcK
re
nt

Proteus
ce

E. coli
Klebsiella
dy
tu

46.target of 2nd generation cephalosporins

lsa
ic
ed
M

atharali187.blogspot.com
 HEN PEcKS

H. flu

6
Enterobacter

01
Nesseria

-2
Proteus
E. coli

11
Klebsiella
Serrati

20
n
io
ss
47.side effects of vancomycin
se
re

NOT
nt

Nephrotoxicity
Ototoxicity
ce

Thrombophlebitis ("red man" syndrome)

dy
tu

48.drugs for pseudomonas

lsa
ic
ed
M

atharali187.blogspot.com
 TCP

Ticarcillin
Carbenicillin
Piperacillin

6
01
Also 3rd gen cephs

-2
49.spectrum of ampicillin/amoxicillin

11
20
Ampicillin/amoxicillin HELPS kill enterococci

H. flu

n
E. coli
Listeria io
ss
Proteus
se

Salmonella
enterococc
re
nt

50.properties og aminoglycoside
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 Mean" GNATS cannot kill anerobes

"Mean" = bacteriocidal
Gentamicin
Neomycin

6
Amikacin

01
Tobramycin
Streptomycin

-2
11
Require O2 for uptake, therefore they are not effective against
anaerobes

20
NOT

n
Nephrotoxic (esp when used with cephs)
io
ss
Ototoxic (esp when used with diuretics)
Teratogen
se
re

51.tetracyclin are effective against

nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 VACUUM THe BedRoom

Vibrio
Acne
Chlamydia

6
Ureaplasma

01
Urealyticum
Mycoplasma

-2
Tularemia

11
H. pylori
Borrelia

20
Rickettsia

n
52. ChloramPhenicol:
io
ss
The only one with a “P”, thus the only one inhibiting Peptide
bond formation (by peptidyltransferase).
se

53. Macrolides:
re

Prevent the Movement of ribosomes.

Prevents translocation.
nt
ce

54. Tetracyclines (TTC):

tRNA Tries but can’t.
Prevents the aminoacyl-tRNA from attaching to the A site of the
dy

ribosome.
tu
lsa
ic
ed
M

atharali187.blogspot.com
 55. Clindamycin:
Makes ribosomes Cling to mRNA.
Prevents translocation

6
CNS Pharma

01
-2
1.effects via Mu opiates receptors

11
"SACRUM"

20
 Sedation

n
 Analgesia

Constipation io
ss

se

 Respiratory depression

 Euphoria
re

 Miosi
nt

2.antipsychotics:uses
ce

S.O.M.A.T.I.C "
dy
tu

 Schizophrenia
ls

 Organic brain syndromes

a
ic
ed
M

atharali187.blogspot.com
  Mania

 Anxiety

 Tetanus

6
 Intractable cough

01
 Control of vomiting

-2
11
3.lithium adverse effects

20
LITHIUM"

n
 Lethargy / Leucocytosis io
ss
 Intentional Tremor
se

 Teratogenicity
re

 Hypothyroidism
nt

 Insipidus [Diabetes insipidus]

ce

 Urine excess
dy

 Metallic taste
tu
ls

4.morphine adverse effects

a
ic
ed
M

atharali187.blogspot.com
 MORPHINE "

 Miosis

 Oliguria

6
 Respiratory depression

01
 Pruritus

-2
 Hypotension

11
 Infrequency (constipation)

20
 Nausea

Emesis (Vomiting)

n


io
ss
5.lithium uses
se

LIBRA '
re

 Leukopenia
nt

 Inappropriate ADH secretion syndrome (SIADH)

ce

 Bipolar disorder
dy

 Recurrent neuropsychiatric syndrome

tu

 Agranulocytosis
lsa
ic
ed
M

atharali187.blogspot.com
 6. drugs for alzheimer

DR.GangaTejwani
d=donepezil
r=rivastigmine

6
g=galantamine

01
t=tacrine

-2
11
7. s/e phenytoin

20
adverse effect of phenytoin:

n
PHENYTOIN
io
ss
P-450 interaction
Hirsutism
se

Enlarged gums
Nystagmus
re

Yellow skin(discolouration)
nt

Teratogenicity
Osteomalacia
ce

Interference with B-12 metabolism

Neuropathies-ataxia,vertigo
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 8. antiepileptics' classification

B - barbiturates D-deoxybarbitarates
H - hydantoin I - iminostilbene
S - succinamide A-aliphatic carbxylic acid

6
B -benzodiazepines

01
C - cyclic GABA analogue
P - phenyl triazine

-2
N - newer drugs

11
BD HISAB Ce PiNa

20
9. ATYPICAL ANTIPSYCHOTICS

n
ORCAS (Brand names in parentheses)
io
ss
Olanzapine (Zyprexa)
se

Risperidone (Risperdal)
Clozapine (Clozaril)
re

Aripiprazole (Abilify)
(Seroquel) Quetiapine
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 10. Side effects of clozapine

Side effects of clozapine MASS

M myocarditis
A agranulocytosis*

6
S seizures

01
S sialorrhea

-2
11. short acting BZDs
TOM

11
Triazolam
Onazelam

20
Midazolam

n
12. Adverse effects of Diazepam
io
ss
ADVERSE effects of Diazepam-DIAzEPAN
D-Dizziness,disorientation,dry mouth
se

I-impaired vision
A-Amnesia
re

z
nt

E-elderly
P-Psychomotor skill impairment
ce

A-Ataxia, apnoea in sleep

N-Neonatal resp depression, night awakening
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 13. PHENYTOIN ADVERSE EFFECT

HOT MALIKA
H- HIRSUTISM N HYPERTROPHY OF GUM
O- OSTEOMALACIA

6
T-TERATOGENICITY

01
M- MEGALOBLASTIC ANEMIA

-2
A- ATAXIA

11
L- LYMPHDENOPATHY
I- INHIBIT INSULINE

20
K- VIT K DEFICIENCY
A- ARRYTHMIA

n
14. Adv. effects of Carbamazepine
io
ss
Adv effecta of Carbamazepine(anti-epilepsy)
se

Mnemonic- CARBA MEAN

re

C-Confusion
A-Ataxia
nt

R-Rashes
ce

B-Blurring of vision
A-Aplastic anaemia
dy

15.Parkinsonism management
tu

SALAD
lsa
ic
ed
M

atharali187.blogspot.com
 Selegline

Anticholinergics(trihexyphenidyl,benztropine)

L.dopa +decarboxylase(carbidopa)

6
Amantididne

01
Dopamine receptor agonists(bromocriptine,pergolide)

-2
16. MAOIs: indications MAOI'S:

11
Melancholic [classic name for atypical depression]
Anxiety

20
Obesity disorders [anorexia, bulemia]
Imagined illnesses [hypochondria]
Social phobias

n
io
· Listed in decreasing order of importance.
ss
· Note MAOI is inside MelAnchOlIc.
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 17. Opioids: effects BAD AMERICANS:
Bradycardia & hypotension
Anorexia
Diminished pupilary size
Analgesics

6
Miosis

01
Euphoria
Respiratory depression

-2
Increased smooth muscle activity (biliary tract constriction)

11
Constipation
Ameliorate cough reflex

20
Nausea and vomiting
Sedation

n
18. SSRIs: side effects SSRI:
Serotonin syndrome io
ss
Stimulate CNS
se

Reproductive disfunctions in male

Insomnia
re

19. Inhalation anesthetics SHINE:

nt

Sevoflurane
Halothane
ce

Isoflurane
Nitrous oxide
dy

Enflurane
tu

· If want the defunct Methoxyflurane too, make it MoonSHINE.

lsa
ic
ed
M

atharali187.blogspot.com
 20. Benzodiazapines: ones not metabolized by the liver (safe to use in
liver failure) LOT: Lorazepam Oxazepam Temazepam

21. Benzodiazepines: actions

"Ben SCAMs Pam into seduction not by brain but by muscle":

6
Sedation

01
anti-Convulsant
anti-Anxiety

-2
Muscle relaxant
Not by brain: No antipsychotic activity.

11
22. Benzodiazepenes: drugs which decrease their metabolism

20
"I'm Overly Calm":
Isoniazid

n
Oral contraceptive pills
Cimetidine
io
ss
· These drugs increase calming effect of BZDs by retarding
metabolism.
se

23. Anesthesia: 4 stages "Anesthesiologists Enjoy S & M":

re

Analgesia
Excitement
nt

Surgical anesthesia
ce

Medullary paralysis
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 24. Sodium valproate: side effects VALPROATE:
Vomiting
Alopecia
Liver toxicity
Pancreatitis/ Pancytopenia

6
Retention of fats (weight gain)

01
Oedema (peripheral oedema)
Appetite increase

-2
Tremor

11
Enzyme inducer (liver)

25. Methyldopa:

20
side effects METHYLDOPA:
Mental retardation

n
Electrolyte imbalance
Tolerance io
ss
Headache/ Hepatotoxicity psYcological upset
se

Lactation in female
Dry mouth
re

Oedema
Parkinsonism
nt

Anaemia (haemolytic)
ce

26.benzodiazepine actions
dy

SAMA
tu

Sedation
lsa
ic
ed
M

atharali187.blogspot.com
 Anticonvulsive

Muscle relaxant

Anti-anxiety

6
27.Benzodiazepine side effects

01
5 As

-2
Addiction

11
Additive sedation

20
Amnesia

Ataxia

n
Abjection (depression) io
ss
28. Gen anesthetics
se

SHINED
re

Sevoflurane
nt

Halothane
ce

isoflurane
dy

NO
tu

Enflurane
ls

Desflurane
a
ic
ed
M

atharali187.blogspot.com
 Endocrinology

6
1.Pituitary hormones

01
FLAGTOP:

-2
Follicle stimulating hormone
Lutinizing hormone

11
Adrenocorticotropin hormone
Growth hormone

20
Thyroid stimulating hormone
Oxytocin

n
Prolactin
io
ss
2.progestorone actions
se

PROGESTE:
Produce cervical mucous
re

Relax uterine smooth muscle

Oxycotin sensitivity down
nt

Gonadotropin [FSH, LH] secretions down

ce

Endometrial spiral arteries and secretions up

Sustain pregnancy
dy

Temperature up / Tit development

Excitability of myometrium down
tu

3.Hyperthyroidism sign and symptoms

lsa
ic
ed
M

atharali187.blogspot.com
 THYROIDISM:
Tremor
Heart rate up
Yawning [fatigability]
Restlessness

6
Oligomenorrhea & amenorrhea

01
Intolerance to heat
Diarrhea

-2
Irritability

11
Sweating
Musle wasting & weight loss

20
4.adrenal gland functions

n
ACTH:
Adrenergic functions
io
ss
Catabolism of proteins/ Carbohydrate metabolism
T cell immunomodulation
se

Hyper/ Hypotension (blood pressure control)

re
nt

5.oestrogen functions
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 OESTROGEN SUX:
Organ development (sex organs)
Endocrine: FSH and LH regulation
Secondary sex characteristics development
Tropic for pregnancy

6
Receptor synthesis (of progesterone, oestrogen, LH)

01
Osteoporosis decrease (inhibits bone reabsorption)
Granulosa cell development

-2
Endocrine: increases prolactin secretion, but then blocks its effect

11
Nipple development
Sex drive increase

20
Uterine contractility increase
oXytocin sensitivity increase

n
6.aldosterone:regulation of secretion from adrenal cortex
io
ss
RNAs
Renin-angiotensin m echanism
se

Na concentraton in blood
ANP (atrial natriuretic peptide)
re

Stress
nt

7.Hypercalcemia
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 Bones, Stones, Groans, Moans":
Bones: pain in bones
Stones: renal
Groans: pain
Psychic moans/ Psychological overtones: confused state

6
01
8.Pheocromocytoma

-2
PHEochromocytoma":
Palpitations

11
Headache
Edisodic sweating (diaphoresis)

20
9.Thyroid carcinoma

n
Most Popular is Papillary.
· Clinical features: io
ss
Papillae (branching)
se

Palpable lymph nodes

"Pupil" nuclei (Orphan Annie)
Psammoma bodies within lesion (often)
re

· Also, has a Positive Prognosis (10 year survival rate: 98%)

nt

10.thyroid storm
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 Storm HITS girls cAMP":
Thyroid storm due to:
Hyperthyroidism
Infection or Illness at childbirth
Trauma

6
Surgery

01
· girls: Thyroid storm more common in females.
· cAMP: Tx involves high dose of beta blockers (beta receptors work

-2
via cAMP)

11
11.hypothyroidism

20
A SCHISM among the Axis during WWII":
Addison disease

n
Subacute thyroiditis
io
Cretinism/ Cold intolerance/ Constipation
ss
Hashimoto's disease
Infectious-subacute thyroiditis
se

Silent thyroiditis
Myxedema coma
re

12.cushing synjdrome
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 CUSHING:
Central obesity/ Cervical fat pads/ Collagen fiber
weakness/ Comedones (acne)
Urinary free corisol and glucose increase
Striae/ Suppressed immunity

6
Hypercortisolism/ Hypertension/ Hyperglycemia/ Hirsutism

01
Iatrogenic (Increased administration of corticosteroids)
Noniatrogenic (Neoplasms)

-2
Glucose intolerance/ Growth retardation

11
13.addison disease

20
ADDISON:
Autoimmune

n
DIC (meningcoccus)
io
Destruction by cancer, infection, vascular insufficiency
ss
Iatrogenic
Sarcoidosis, granulomatous such as TB histiomycosis
se

hypOtension/ hypOnatermia
Nelson's syndrome [post adrelectomy, increased ACTH]
re

14.Goiter
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 GOITRE:
Goitrogens
Onset of puberty
Iodine deficiency
Thyrotoxicosis/ Tumor/ Thyroiditis [Hashimoto's]

6
Reproduction [pregnancy]

01
Enzyme deficiencies

-2
15.dibetes complicatins

11
SHAKE:
Stroke

20
Heart attack
Amputations

n
Kidney disease
Eyes (vision loss)
io
ss
16.steroid side effects
se

CUSHINGOID
re

 Cataracts
nt

 Ulcers
ce

 Skin: striae, thinning, bruising

dy

 Hypertension/ Hirsutism/ Hyperglycemia

tu

 Infections
ls

 Necrosis, avascular necrosis of the femoral head

a
ic
ed
M

atharali187.blogspot.com
  Glycosuria

 Osteoporosis, obesity

 Immunosuppression

6
 Diabetes

01
-2
17.growth hormone toxicity

11
HE-SSP

20
Hyperglycemia

Edema

n
Scoliosis io
ss
Slipped capital femoral epiphysis
se

Pseudomotor cerebri
re
nt

18.growth hormone toxicity in adults

ce

PMA
dy

Peripheral edema
tu

Myalgia
ls

Athralgia
a
ic
ed
M

atharali187.blogspot.com
 19.Follitropin alfa and Hcg toxicity

OMG-Humna Doing Exercise

6
Ovarian hyperstimulation

01
Multiple pregnencies

-2
Gynecomestia in MEN

11
Headach

20
Deoression

Edema

n
20.amidarone side effects io
ss
6 P's:
se

Prolongs action potential duration

Photosensitivity
re

Pigmentation of skin
nt

Peripheral neuropathy
Pulmonary alveolitis and fibrosis
ce

Peripheral conversion of T4 to T3 is inhibited -> hypothyroidism

dy

21.oxytocin side effects

tu

Hair-PUFF
lsa
ic
ed
M

atharali187.blogspot.com
 Hypotension

Placental abruption

Uterine rupture

6
Fetal distress

01
Fluid retension

-2
22.prednisone –toxicity

11
BG-SMOAG

20
Behavioural changes

Glucose intolerance

n
Salt retension io
ss
Muscle wasting
se

Osteoprosis
re

Adrenal suppression
nt

Growth Inhibition
ce
dy

23.Fludocortisoe-toxicity
tu

CSS
ls

Cogestive heart failure

a
ic
ed
M

atharali187.blogspot.com
 Salt and fluid retension

Symptoms of glucocorticoid

23.Tamoxifere-toxicity

6
THE

01
Thromboembolism

-2
Hot flushes

11
Endometrial

20
24.Anastrozole-toxicity

A-ROAD-MATCH

n
Athralgia io
ss
Reduced bone mineral density
se

Osteoarthritis
re

Arthritis
nt

Disk herniation
ce

Musculoskeletal Disorders
dy

Arthrosis
tu

Cervical spondylosis
ls

Hot flushes
a
ic
ed
M

atharali187.blogspot.com
 25.Prednisone –clinical applications

HOM

Hematalogic cancer

6
Organ transplantation

01
Many inflammatory conditions

-2
26. Hormones that Increase Blood Glucose

11
"STENGG"

20
Somatotropin (growth hormone)
Thyroid hormones (thyroxine and triiodothyronine)

n
Epinephrine
Norepinephrine
io
ss
Glucagon
Glucocorticosteroids
se
re

27.PTU-mechanism
nt

It inhibits PTU:
ce

Peroxidase/ Peripheral deiodination

Tyrosine iodination
dy

Union (coupling)
tu
ls

28.steroid side effects

a
ic
ed
M

atharali187.blogspot.com
 BECLOMETHASONE:
Buffalo hump
Easy bruising
Cataracts
Larger appetite

6
Obesity

01
Moonface
Euphoria

-2
Thin arms & legs

11
Hypertension/ Hyperglycaemia
Avascular necrosis of femoral head

20
Skin thinning
Osteoporosis
Negative nitrogen balance

n
Emotional liability
io
ss
se
re

29.insulin mixing
nt

"Not Ready, Ready Now":

ce

Air into NPH

Air into Regular
Draw up Regular
dy

Draw up NPH
tu

30.coricosteroid side effects

lsa
ic
ed
M

atharali187.blogspot.com
 CUSHINGS BAD MD:
Cataracts
Up all night (sleep disturbances)
Suppression of HPA axis
Hypertension/ buffalo Hump

6
Infections

01
Necrosis (avascular)
Gain weight

-2
Striae

11
Bone loss (osteoporosis)
Acne

20
Diabetes
Myopathy, moon faces
Depression and emotional changes

n
GIT-Pharma io
ss
se

1. the PPIs
re

OLPER(milk )
nt

Omeprazole
ce

Lansoprazole
dy

Pantoprazole
tu

Rabeprazole
lsa
ic
ed
M

atharali187.blogspot.com
 Esomeprazole

2.types of laxatives

Types of laxatives

6
"Boss"

01
-2
Bulk laxatives.
Osmotic laxatives.

11
Stimulant(irritant)laxatives.

20
Stool Softeners.

n
Or "Bios"
io
ss
Bulk laxatives.
se

irritant(Stimulant)laxatives.
Osmotic laxatives.
re

Stool Softeners.
nt
ce
dy
tu
ls

ASTHMA-PHARMA
a
ic
ed
M

atharali187.blogspot.com
 1.management of asthma

ASTHMA

Adrenergics
Steroids

6
Theophyllines)

01
Hydration

-2
Mask

11
2.asthma participating agents

20
DIPLOMAT:
Drugs (aspirin, NSAIDs, beta blockers, etc)

n
Infections (URTI/LRTI)
io
ss
Pollutants (at home, at work)
Laughter(emotion)
se

Oesophageal reflux (nocturnal asthma)

Mites
re

Activity and exercise

nt

Temperature (cold)
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 3. Asthma acute attack: 5 life threatening signs SHOCK:
Silent chest
Hypotension
One third of best/predicted PFR
Cyanosis

6
Konfusion

01
-2
4. Asthma: management of acute severe “O SHIT“:

11
Oxygen (high dose: >60%)
Salbutamol (5mg via oxygen-driven nebuliser)

20
Hydrocortisone (or prednisolone)
Ipratropium bromide (if life threatening)

n
Theophylline (or preferably aminophylline-if life threatening
io
ss
se

5. AAAA PPPP:
Airway obstruction
Angina
re

Anxiety
nt

Asthma
ce

Pneumonia
Pneumothorax
Pulmonary Edema
dy

Pulmonary Embolus
tu
lsa
ic
ed
M

atharali187.blogspot.com
 NSAIDS-PHARMA

1. NSAIDs-classification:
SOFIA PaBe..
S-salicylate

6
O-oxicame derivatives

01
F-fenamic acid deri
I-indol deri

-2
A-aryl acetic acid deri
P-propionic acid deri

11
-pyrrolo pyrrolo deri
-pyrazolon deri

20
-paramine phenol deri
B-benzoxazocin deri

n
io
ss
2. NSAIDs: contraindications
se

NSAID:
N-ursing and pregnancy
re

S-erious bleeding
nt

A-llergy/ Asthma/ Angioedema

ce

I-mpaired renal function

D-rug (anticoagulant)
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 Prostaglandin-pharma

6
01
-2
11
20
n
io
ss
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 PROSTAGLANDINS confusion

A)All have "1 MISS"

means
MISoprostol is PGE1.

6
01
B)cErviprimE has 2E so
cErviprimE is PGE2.

-2
11
C)DInoproSTONE
DI=2

20
Remember that "stonE" in both(2) kidney n "stonE" has "E".
So DINOPROSTONE is PGE2.

n
D)DINO mario has 2 FArari CAR.
io
ss
DINO-DINOPROST
2 FArari-F2A [A for Alpha]
se

CAR-CARBOPROST
so
re

DINOPROST n CARBOPROST r PGF2alpha

nt

Note: DINOPROSTONE is PGE2 which is remember by 2 kidney

ce

stonE bt DINOPROST is PGF2alpha.

dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 By

ALI Zeeshan (QAMC)

6
01
-2
ATHAR ALI (QAMC)

11
NOREEN FATIMA(FJMC)

20
n
io
ss
our group, page and blog
se
re
nt

GROUP
ce

https://www.facebook.com/gro
dy
tu

ups/Medical.study.centre/
lsa
ic

PAGE
ed
M

atharali187.blogspot.com
 https://www.facebook.com/pa
ges/Medical-study-centre-
session-2011-

6
01
2016/1451699768417480

-2
11
BLOG

20
http://atharali187.blogspot.com/

n
io
ss
se
re
nt
ce
dy
tu
lsa
ic
ed
M

atharali187.blogspot.com
 M
ed

.
4
ic
als
tu
dy
ce
nt
re
se
ss
io
n
20
11

atharali187.blogspot.com
-2
01
6
 M
ed
ic
als
tu
dy
ce
nt
re
se
ss
io
n
20
11

atharali187.blogspot.com
-2
01
6